Freedom Leaf, a leading marketing and business resource for the cannabis, industrial hemp, and medical marijuana industries, has its roots in the vision of its founders, representing decades of experience in the marijuana legalization movement. The company does not handle, grow, sell, or dispense marijuana or related products, but rather is a movement marketing company bringing together a fast-growing industry and the public. It does this through a variety of media resources, providing news and industry information, while offering a range of business services, including marketing, advertising, and consulting, to help the many young companies in the industry develop.

In addition to Freedom Leaf’s popular Freedom Leaf magazine, now available in 32 states, the company is also growing on the Internet, with a number of current and developing online sites, all designed to help educate, advocate, and assist in the burgeoning industry:

• FreedomLeaf.com
• MarijuanaNews.com
• LadyCannabis.com
• Cannabis Business University
• CannabisSeminars.com
• CampusCannabisDebate.com
• CannaSpa.com
• Vegasterdam.com

According to the company, Freedom Leaf’s three essential areas of operation are:

1) Licensing of brands, in which licensees can market and sell Freedom Leaf magazine, website advertising, products, services, seminars, musical festivals, and other branded products
2) Acquiring and incubating new and existing businesses entering into the cannabis/hemp industry – ultimately purposed for spin-off
3) Entering into branding, marketing, and promotion contracts, with both profit and non-profit organizations, for which Freedom Leaf has extensive and far-reaching promotional capabilities

In the words of the Freedom Leaf founders:

Richard Cowan (Founder) – “Freedom Leaf, the Marijuana Legalization Company, is focused on ending marijuana prohibition. But this is also an experiment in a new form of social – not just political – activism. We are combining the motivation of entrepreneurial spirit with a devotion to personal liberty. You can’t get more American than that!”

Clifford Perry (CEO, President, Co-Founder) – “The Freedom Leaf vision is to build brands associated with the legalization of marijuana. We are growing a marketing network from the roots up. Our goal is to support the movement. We are focused on advocacy and publishing stories that promote legalization, while appealing to the broader, non-consuming population at the same time.”

For more information, visit http://freedomleaf.com

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Alternet Systems, Inc. (OTCQB: ALYI) is preparing people for a new age of digital living. The company, which invests in technological tools that enable and expedite commerce, is focused on elevating its customers’ – and partners’ – experience with multichannel payments, digital commerce and predictive analytics. By concentrating on improving efficiency, the company is pushing to become a leading global provider in these industries.

As an enterprise accelerator company, Alternet maintains a vigilant eye on the fast growth markets that surround newly-adapted Internet technologies and platforms, such as Internet and mobile commerce, digital currency and cyber-security products and services. Once it spies a high growth opportunity in these markets, the company and its subsidiaries pursue and aim to convert them into income streams.

One key initiative that Alternet has been pursuing and developing is a plan to offer multi-channel payment solutions, as well as Near Field Communication (NFC) point of sale solutions, electronic point of sale modernization and financial services software for the mobile finance and payment processing industry.

This past August, the company achieved a milestone in the multi-channel payment space. Alternet Payment Solutions, a subsidiary of Alternet Systems, joined forces with MUXI to provide U.S. payment processors and independent sales organizations with a flexible, maintained multi-channel point-of-sale payment processing solution. With a prospective market reach that includes over 20 million merchants in the U.S., this is a potentially disruptive offering in the nation’s omni-channel payment processing space and one that is in high demand from small- and medium-sized enterprises who appreciate the affordability of mobile point of sale terminals, as compared to fixed point of sale terminals.

For MUXI, a subsidiary of APPI Group, Alternet makes a formidable partner as it embarks on a run to expand globally. The affiliation with Alternet will enable MUXI to stretch its sales and support presence within the U.S. while relying on the Alternet management team’s century worth of experience and understanding of the payments market.

How does the MUXI technology work? The company’s solution offers customers a point of sale admin platform that gives them complete control over their network and assets, and by complete control, the MUXI means complete control. The platform runs independently of point of sale manufacturers. At the same time, it enables remote and improved application updates across all point of sale platforms. In fact, applications within the platform extend the functions of the point of sale foundation across mobile devices (e.g. smartphones and tablets).

For more information, visit www.alternetsystems.com

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International Stem Cell Corp., a clinical stage biotech company developing novel stem cell-based therapies, has signed a master clinical research agreement with the Florey Institute of Neuroscience and Mental Health to conduct phase I/IIa clinical trial, dose escalation trial of human parthenogenetic stem cells-derived neural stem cells (ISC-hpNSC) in Parkinson’s disease (PD) patients. ISCO said it expects to enroll all patients into the clinical trial in the first quarter of 2016, with interim results available in October.

ISCO is well-paired with the Florey Institute, which is staffed with the largest neuroscience research team in Australia and ranked as one of the world’s leading brain research centers. Also participating in the clinical study is Dr. Andrew Evans, M.D., director of the Movement Disorders Service at the Royal Melbourne Hospital, who will be the study’s principal investigator. Dr. Evans heads numerous clinical research trials, and has extensively published on PD, particularly addressing symptoms that impact on the quality of life of sufferers. He is also a member of the Melbourne Health Ethics Committee.

“We recently received authorization to initiate phase I/IIa and now we are moving forward towards formal engagement of the clinical site to conduct this study. We are excited to work together with the Florey to conduct the clinical trials of ISC-hpNSC at the Royal Melbourne Hospital,” Russell Kern, PhD, executive vice president and chief scientific officer of ISCO, stated in the news release.

ISC-hpNSC consists of a highly pure population of neural stem cells derived from human parthenogenetic stem cells. Preclinical studies in rodents and non-human primates have shown improvement in PD symptoms and increase in brain dopamine levels following the intracranial administration of ISC-hpNSC. ISC-hpNSC are safe, well-tolerated and do not cause adverse events such as dyskinesia, systemic toxicity or tumors in preclinical models.

ISCO is also exploring ISC-hpNSC’s potential in broad therapeutic applications for many neurological diseases affecting the brain, the spinal cord and the eye.

For more information, visit www.internationalstemcell.com

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The American Cancer Society estimates that about 21,290 new cases of ovarian cancer will be diagnosed in 2015, and roughly 14,180 women will die from the illness within the United States. These figures outline the severity of ovarian cancer, which is currently the eighth most common cancer among women, as well as the fifth leading cause of cancer-related death among women, according to data from SEER. Over the past forty years, mortality rates for ovarian cancer have recorded a mild decline as a result of the ongoing ‘War on Cancer’, but these improvements pale in comparison to the progress made on some other forms of the disease. Today, nearly half of all cancer patients can expect to live for five or more years after diagnosis with proper treatment.

With this data in mind, the question regarding ovarian cancer becomes clear: Why hasn’t more progress been made toward improving survivability? To understand the answer to this question, one needs to take a closer look at the illness.

Ovarian cancer begins when healthy cells in an ovary mutate and begin to grow uncontrollably, forming a mass known as a tumor. Tumors come in two basic forms – cancerous and benign. While benign tumors can cause problems by continuing to grow, cancerous tumors are, by far, the more dangerous form. Cancerous tumors on the ovaries are malignant, meaning they can continue to grow and spread to other parts of the body. For this reason, catching the disease in its early stages is paramount to improving survivability rates.

When diagnosed early, ovarian cancer is actually an extremely survivable disease. According to data from the American Cancer Society, individuals with ovarian cancer that’s diagnosed in stage I boast a five-year survivability rate of approximately 90 percent. However, this outlook is significantly worse when the illness isn’t discovered until the later stages. In stage II, the five-year survivability rate for invasive epithelial ovarian cancer, which accounts for roughly 85 percent of all cancers of the ovaries, falls to 70 percent. In stage III, survivability is just 39 percent.

With the importance of early detection clearly illustrated, a massively underserved indication within the diagnostic market becomes evident. The National Ovarian Cancer Coalition reports that almost 70 percent of women diagnosed with the common epithelial ovarian cancer are not diagnosed until the disease is advanced in stage.

Current ovarian cancer detection methods are hampered by a variety of factors. The simplest check, a pelvic exam, consists of a health care professional feeling the ovaries and uterus for size, shape and consistency. While these tests are relatively effective for some reproductive system cancers, most early ovarian tumors are difficult or impossible for even the most skilled examiner to feel. Screening tests and exams are also used for detection in people who don’t display any symptoms. However, both transvaginal ultrasound (TVUS) and the CA-125 blood test have drawbacks.

In the case of TVUS, sound waves are used to study the reproductive system. These waves can help physicians locate tumors on the ovaries, but they doesn’t help determine if the mass is cancerous or benign. The CA-125 blood test, on the other hand, checks the patient’s blood for high levels of the CA-125 protein, which is commonly associated with ovarian cancer. The effectiveness of this test is also hindered, because many common conditions other than cancer can cause high levels of CA-125.

Avant Diagnostics, Inc. (OTCQB: AVDX) is developing a novel approach to ovarian cancer screening that has the potential to fill this underserved need in the medical community. OvaDX® is a sophisticated microarray-based test that measures the activation of the immune system in blood samples in response to early stage ovarian tumor cell development. In clinical research, OvaDX has displayed high sensitivity and specificity for all types and stages of ovarian cancer – including stage IA-IV borderline serous, clear cell, endometrioid, mixed epithelial, mucinous, serous and ovarian adenocarcinoma. Following FDA approval, Avant plans to market OvaDx to doctors as a supplement to existing tests for women seeking greater wellness, as well as those in the elevated risk category for ovarian cancer.

As of its latest update, Avant had received FDA approval for ovarian cancer specimens to be used in a forthcoming validation study to support a pre-submission package to the FDA. After this package is submitted and reviewed, the company will look to commence the OvaDx 510(k) trial, which it plans to conduct in a double-blinded environment supervised by an independent clinical research organization.

For more information, visit www.avantdiagnostics.com

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Cherubim Interests, Inc. (OTC: CHIT) is an investment company with its energy and resources centered on single and multi-family dwellings for purchase. The company also targets undervalued commercial assets. Cherubim’s business model is geared toward becoming a leader in property management, alternative construction, multifamily real estate, and investment opportunities. A trademark of the company is its hands-on involvement with each project from start to finish, addressing general management, acquisitions and construction. Company initiatives promote safer living and enhanced lifestyles that drive maximized shareholder value for its investors.

In a recent adjunct move to facilitate its growth plans, Cherubim signed a Memorandum of Understanding (MOU) with United Cannabis Corp. (OTCQB: CNAB) to supply, deploy and provide the technical means to cultivate cannabis.

“This industry is moving very rapidly,” stated Patrick J. Johnson, CEO of Cherubim Interests, Inc., in a recent news release. “As we see the front of legalization push across states and even into the platforms of the next presidential election, companies are scrambling to catch up. The market is there, the demand is high, but the supply from legal cultivators is low. Cherubim Interests and BudCube are uniquely positioned at this perfect apex of an emerging, billion dollar market; we are positioning ourselves to meet the impending demand by supplying the facility necessary to bring existing as well as start-up companies into full scale production in a matter of months.”

Cherubim will own, manage and develop new properties while BudCube will oversee the technology and cannabis cultivation system application. Both companies will partner to deliver single and multi-tenant solutions for prospective cannabis growers. This strategy is expected to deliver handsome financial growth numbers for both companies.

Cherubim is led by a group of highly experienced directors and a management team with expertise in a variety of disciplines ranging from property management and construction to finance. CHIT is determined to fulfill its vision of becoming a leader in the fields of alternative construction, multi-family real estate development, property management, and investment.

For more information, visit www.cherubiminterests.com

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Environmental awareness, recycling, saving the rain forests, reducing carbon emissions and lowering carbon footprints are all much needed practices for running a business in the 21st century. Contradictory to so many popular science fiction blockbusters, there is only one planet that we can call home, so it is refreshing to see more and more people and businesses implementing environmentally friendly operations into their business strategies. Legacy Ventures International, Inc. (OTCQB: LGYV) spearheads this effort with its Boxed Water product.

Since ‘Being Green’ is in and a recent climate agreement in Paris was reached, Legacy Ventures is in a prime position for growth with its Boxed Water product. Boxed Water provides an alternative sustainable package for water consumption, as it is packaged in a 100 percent recyclable carton and not a plastic bottle. In shipping alone, Boxed Water significantly lowers the carbon footprint of traditional portable water solutions. One truckload of Boxed Water cartons is equivalent to twenty-six truckloads of plastic bottles. Boxed Water supports world water relief, reforestation, and environmental protection projects.

Political changes like the agreements reached at the 2015 United Nations Climate Change Conference in Paris are springboards for companies to alter and change the way they do business in order to comply with upcoming requirements and legislation. Legacy Ventures had the foresight to position itself to capitalize on this evolving landscape with a game-changing product like Boxed Water.

‘Waste not, want not’ should be one of the slogans for Boxed Water. Making bottles to meet America’s demand for bottled water uses more than seventeen million barrels of oil annually, enough to fuel 1.3 million cars for a year. Americans used about fifty billion plastic water bottles last year. However, the U.S.’s rate for recycling plastic is only 23 percent, which means 38 billion water bottles – more than $1 billion worth of plastic – are wasted each year, according to a ban the bottle website.

Boxed Water is the future, and Legacy Ventures is positioned for serious growth, especially, considering recent developments around the globe.

For more information, visit www.legacyventuresinc.com

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Healthy grocery shopping can be hard enough when it’s just for you. Now imagine the headaches that accompany shopping for your entire family, while avoiding potentially dangerous foods due to your family members’ allergies and dietary requirements. Luckily, a cutting-edge company, Content Checked Holdings, Inc. (OTCQB: CNCK), has done all the research for you and created a suite of easy-to-use apps readily available to download on your smartphone or tablet.

ContentChecked is an app that will help users make better food choices for their food allergy and intolerance needs. When in the grocery store, users can scan a product barcode on a food or beverage product. The app will then tell the user whether or not that product is suitable for them based on their allergy settings and will provide the user with similar alternatives if the product does contain one or more of their allergens. Educating consumers about food ingredients and helping them avoid trips to the emergency room are two of the company’s goals when developing apps.

The company began with a simple idea: to ease the frustration of a father trying to grocery shop for his daughter and her friends while taking into consideration their countless food allergies and intolerances. Transforming the trudging task of picking out groceries into a fun, interactive and educational scavenger hunt is the ultimate goal of Content Checked Holdings.

In today’s health conscience world where consumers test diet after diet, it is refreshing to find a company like Content Checked whose mission is to educate the consumers on products readily available in most local grocery stores throughout the U.S. Once we inculcate ourselves on what foods are bad for our diet and which alternatives we should put in the shopping cart instead, our lives will become much healthier and food will become more fulfilling.

For more information, please visit the company’s website at www.ContentChecked.com.

In a world where alternative energy trends are increasingly becoming essential, Dominovas Energy Corporation (OTCQB: DNRG) seeks to lead the way with its clean electricity technology. The company focuses its innovative endeavors on providing green electricity to areas all over the world while promising low-costs and high-output.

Dominovas Energy uses solid oxide fuel cell (SOFC) technology as the core of its proprietary RUBICON™ system. SOFCs have a minimal environmental impact because they generate electricity without harmful emissions while keeping production costs down.

Using this technology, RUBICON™ converts practically any hydrocarbon fuel into usable, clean electricity, resulting in a more efficient, and environmentally friendly operational system, when compared to standard power productions. This innovative fuel cell system emits heat when generated and allows any excess to be used for heating water, producing steam, supporting cooling systems, and any other additional energy uses. All the while, the RUBICON™ produces less greenhouse gas pollutants, which can damage the environment.

Dominovas Energy can also place its power generating fuel cell systems in immediate proximity to the end user to ensure lower operational costs by avoiding costly infrastructure, transmission line maintenance, vandalism and sabotage, and unrecoverable transmission degradation and other typical challenges. The company has also built-in the ability to remotely monitor its system and promises 100% reliability of the energy produced. The company will have the capability to identify and correct systems errors long before clients realize there is any complication, and, because the systems are modular, the entire megawatt complex does not have to be shut down, which means the client never loses power. This monitoring system uses a customized 5G wireless transmission that trumps the average 3G and 4G speeds.

Led by scientist and engineer, Dr. Shamiul Islam, the company says its RUBICON™ fuel system technology is “quickly becoming the ‘Platinum Standard’ by which all other fuel technologies are measured.”

Dominovas Energy believes in creating alternative green energy solutions that are cost effective and highly efficient. The company’s proprietary RUBICON™ system exemplifies these goals by demonstrating its value as a superior-grade product that keeps clients confident that their green energy is of the highest quality.

For more information, visit www.dominovasenergy.com

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There are more choices available today than ever before for consumers who want to enjoy a night out, either with their friends and colleagues or their families. One might even say there are too many options competing for consumer’s entertainment dollar, making the very task of selecting a venue something that routinely becomes an open debate, as a given party’s tastes and interests all jockey for position. Hence a continuing trend within the industry toward consolidating more options into a single location.

One of the segments of the market where this is especially clear is at the box office, which saw slight declines in ticket sales last year to around $10.4 billion in North America and $36.4 billion worldwide, according to the MPAA, as pressure from streaming sources like Netflix (NASDAQ: NFLX) and Amazon (NASDAQ: AMZN) Video continue to mount. This trend has meant big business for innovative private companies like Alamo Drafthouse Cinemas, one of the first movers when it comes to dine-in theaters combining more comfortable seating with casual dining and alcoholic beverage choices in order to win over increasingly difficult to court movie goers.

The sector’s largest players, such as AMC Entertainment Holdings (NYSE: AMC), are also gravitating more and more in this direction, with an increasingly prominent bottom line component that consists of dine-in theaters. This move has been tracked closely and emulated by other motion picture exhibitors such as Regal Entertainment Group (NYSE: RGC) and more globally-focused players like Cinemark (NYSE: CNK), which recently opened a new 14-screen theatre in Roanoke, Texas, based on its NextGen cinema design concept, featuring luxury recliners and a larger menu, including a full selection of alcoholic beverages. A recent survey by RBC indicates that nearly half of all respondents do not have a favorite theater chain, but the overwhelming majority did express a desire to patronize locations that featured upgraded seating and concession options, as well as those venues which offered alternative content. To wit, 24 percent of respondents in the RBC survey cited AMC by name, likely due to its continuing emphasis on improving the overall customer experience by offering precisely such expanded offerings.

But why stop at dinner and a movie? Still quite rare, but increasingly prominent up-and-comers such as award-winning pioneer Latitude 360 (OTC: LATX) have already jumped ahead a page. Latitude 360 fuses together just about every option consumers have to choose from into a winning package that elegantly combines diverse entertainment options under a single roof. Sure, consumers can enjoy an exceptional meal and drinks off of a giant menu, alongside a Hollywood blockbuster displayed on a 25 by 11 foot screen backed up by over 10,000 watts of thumping DTS™ digital surround sound at a luxurious, yet intimate, dine-in Cinegrille® cinema at one of Latitude 360’s growing footprint of 35,000 to 85,000 square foot locations – but they can also take in the numerous other entertainment options as well. Options ranging from a full sports bar with HD screens and a separate sports theatre, to Las Vegas-style live entertainment such as music and comedy, as well as dancing, premium bowling, a game arcade, and even a luxury cigar lounge.

This mega fusion of entertainment venue options, which the company touts as the “360 Experience,” takes brilliant advantage of economies of scale, while also offering consumers the most compelling entertainment one-stop-shop available anywhere. No longer must families or coworkers argue over where to go for lunch, or for dinner and a movie, so long as there is a Latitude 360 in their town. The company has even been breaking new ground in terms of the options available, with recent additions such as a cutting edge real money fantasy sports gaming platform called 360 Fantasy Live, which gives guests the ability to participate in daily contests while watching the game on massive HD screens in comfort. This one option is a huge advantage for LATX, given that there are now nearly 52 million players in North America alone, according to 2015 data from the Fantasy Sports Trade Association, and daily fantasy sports games will generate some $2.6 billion in entry fees this year, with the market growing at a rate of 41 percent per annum through 2020 to over $14.4 billion (Eilers Research).

Tack on how LATX has recently embraced an on-premise integration of a branded ordering and payment app via partnership with mobile payments solution provider MyCheck, and it becomes readily apparent how this incredibly investor-accessible company with five locations throughout the U.S. is laser-focused on maximizing the customer experience. Set to debut in the coming months, the branded app will not only revolutionize the customer experience by allowing guests to easily order/reorder from the menu, it will also allow them to review and split the bill amongst friends from their smartphone(s), subsequently giving them access to such emerging payment methods as Apple’s (NASDAQ: AAPL) Apple Pay – the app will also provide LATX’s business model with overhead shearing benefits.

Latitude 360 is clearly ahead of the curve when it comes to the entertainment venue market, fully answering questions that many consumers have not yet even begun to ask, but one of the driving reasons behind the success of the company’s upscale multi-dimensional entertainment eateries is an overarching commitment to top shelf customer service. The company’s highly trained and attentive staff will have their jobs made easier by the addition of the new branded app, opening doors to enhanced service capabilities in other areas, likely leading to an even stronger rapport with local markets, such as those surrounding existing Latitude 360 locations in Jacksonville, Pittsburgh and Indianapolis, as well as its newly acquired locations in Syracuse, and Bethlehem, PA. The company has also signed a deal with established restaurant and hospitality group, Al Sedriyah, opening up the Latitude 360 brand for franchise locations in Qatar and Saudi Arabia, showing that this business model not only has universal appeal, but that management has no intentions of slowing down.

For more information on the company visit www.latitude360.com

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GTX Corp. (OTC: GTXO) provides GPS, cellular, and BLE solutions through wearable technology. The company believes in giving the global community tracking technology that empowers families and businesses to locate anyone they need. Not only does GTX Corp. deliver GPS solutions, it also markets a simpler, yet lifesaving product called Code Amber Alertag. This is a small tag that attaches to keychains and gives access to the wearer’s medical information in case of an emergency.

First responders are trained to look for the medical information of injured individuals upon arriving at the scene. Unfortunately, this important information is rarely found, which leads many people to suffer from preventable medical errors, the fifth leading cause of death in the United States. Fortunately, Alertag provides EMTs with a special code that can be entered into the IDAmber.com website in order to retrieve any medical information on allergies or pre-existing conditions that could help during an emergency.

Code Amber Alertag also offers multiple tiers of privacy protection for wearers. First, the security code on the back of the tag only gives public access to medical information such as allergies and chronic conditions. For a full medical history, a special key code is required that should be given to the wearer’s emergency contacts. The wearer also has a password to log in and edit any of this information. Alertag wearers can include any information they want when signing up, such as photos, documents, and contact information.

Interestingly, one out of four people have medical conditions that could complicate emergency treatments. Having this information on hand gives first responders the ability to quickly assess the situation and determine a proper treatment. Holding this product also helps when friends and family are too overwhelmed to recall pertinent health information during an emergency. Similarly, if an injured person is found alone, he/she may not be able to communicate these details.

GTX Corp. aims to cut down on the number of medical errors through its Code Amber Alertag, which can help children, adults, seniors, workers, and even animals.

For more information, visit www.gtxcorp.com

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