The global wound care market recently reached revenues of more than $20 billion (http://dtn.fm/W1wjB) at the end of 2016, based on sales at the manufacturer’s level. Specifically, the burn care market is expected to grow at a CAGR of 6.8% from $1.68 billion in 2016 to more than $2.33 billion by the end of 2021 (http://dtn.fm/I6abR). The growth in these markets has been largely attributed to factors such as the rising number of burn accidents, an aging population, and the rise in cardiovascular diseases, diabetes, obesity, and other diseases that can cause skin-related problems.

Currently, wound care ranges from anti-infectives, ulcer wound management, moist dressings, and negative pressure wound therapy to wound closure and even conventional skin grafts. These treatments can be extremely painful, slow-to-heal, and are more likely to face complications along the way. Today, more is being done to help patients suffering from skin problems, some of which include a rise in health care expenditure, more government initiatives, an increase in the number of emergency centers and burn units, and a growing understanding of the various treatment options.

In addition, more innovative forms of treatment are slowly being introduced. RenovaCare, Inc. (OTCQB: RCAR), a development stage biotechnology company focused on acquiring, researching, developing, and commercializing first-of-their-kind self-donated stem cell therapies for the regeneration of human organs, is in the process of developing a product that targets issues relating to the human body’s largest organ, the skin.

The company’s CellMist™ system uses a patient’s own stem cells and is applied onto wounds and burns using its SkinGun™. The technology is able to regrow the skin across wounds by spreading numerous regenerative islands over the affected area, rather than the wound healing from the outside in. Although still part of an experimental setting, the system has been tested on patients such as Matt Uram, a victim of a fire-related accident during a July fourth celebration, who, within three days witnessed incredible results, with burns almost completely healed and no risk of infection or scarring (http://dtn.fm/uXAR5).

RenovaCare believes the SkinGun™ could replace today’s standards of care, decreasing the need for patients to go through the process of having complicated skin grafts, mesh skin grafts, and other forms of painful treatment.

The company is aiming to get the SkinGun™ FDA-approved in the near future, and research is already underway at RenovaCare to enable the treatment of third degree burns, which are more complex in nature and often come with damage to the muscles and tissue below the skin.

For more information, visit www.RenovaCareInc.com

In the first few months of 2017, MGX Minerals, Inc. (OTC: MGXMF) announced a cheaper lithium extraction process (http://dtn.fm/5xqMc) that yielded 1600mg/L of lithium and also recovered potentially saleable by-products of magnesium, boron and potassium.

The market for lithium-ion batteries is expected to grow in value to $46.21 billion annually within the next five years thanks to growing demand from electric car manufacturers such as Tesla, Nissan and BAIC Motor.

Thanks to its unique characteristics, lithium provides the most energy per weight or volume, so batteries can be made smaller and more efficient. The demand is growing rapidly, and Deutsche Bank (NYSE: DB) and Macquarie Research predict growth rates between 60 and 250 percent in the next few years alone.

Electric cars and consumer products utilizing lithium-ion batteries are not the only reason for lithium’s explosive growth prospects. Renewable energy sources such as wind and solar are also becoming increasingly reliant on lithium-ion battery storage. Without the ability to store clean energy for on-demand delivery to the grid, renewable sources will remain unable to compete with fossil fuel sources.

The increasing demand suggests increased pressure on suppliers, who have been slow to respond with opening up new supply chains. According to a Bloomberg press release (http://dtn.fm/3GtkQ) that quoted the world’s largest lithium producer, Albemarle Corp. (NYSE: ALB), lithium carbonate prices spiked in China from $4,000 in 2014 to over $20,000 per metric ton in 2016.

A lithium mining boom is currently underway. Many companies exploring for lithium have set their sights on Clayton Valley, Nevada, which is home to the only lithium-producing mine in North America. Clayton Valley is attractive, because lithium can be extracted from brine aquifers, rather than high cost hard rock mining. The brine is evaporated in large settling ponds in a process that can take 18-24 months. The low grades at Clayton Valley are offset by large quantities and low costs of the evaporation technique.

MGX, however, has banked on decreasing the evaporation timeline to less than one day. Its patent-pending PetroLithium™ methodology separates valuable minerals from salt water (brine) that accompanies oil and gas production. Until now, petroleum brine has been discarded as a waste product, but MGX is working to develop technology that will extract lithium and other valuable minerals in less than one day while also cleaning the wastewater brine and making it safe for the environment.

In early March, MGX reported that it had concentrated 20 times more lithium than was concentrated through earlier extraction methods (http://dtn.fm/gY6tB), while contaminants were removed using less energy. The company has expanded its mining operations from Alberta into the Lisbon Valley oil and gas field located in the Paradox basin, near Moab, Utah. MGX has also signed an agreement to earn a 50 percent interest in the Paradox Basin Lithium Brine Property, thanks to a recently announce joint-venture with Scientific Metals Corp.

In total, MGX has built a lithium portfolio spanning over 175 million acres, or 2,400 square miles, throughout North America. At current prices, it’s estimated that there could be $18 billion worth of lithium to be mined. The pace appears to be picking up for MGX and lithium mining in general.

For more information, visit the company’s website at www.MGXMinerals.com

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Recent studies undertaken by PWC (http://dtn.fm/dD48p) show that excellent training and development programs are key factors that make an attractive employer, next to opportunities for career progression and financial incentives. The economic landscape in the U.S. is changing, and people are putting more thought into the skills and training they need to succeed in their workplaces.

A Pew Research Center survey (http://dtn.fm/w6J2m) showed that the majority of employees see ongoing training as a very important factor for a successful career. This belief has, in some ways, been confirmed, as a Pew Research Center analysis of government jobs data showed that employment has been rising in professions where more training, education, and experience are required.

The research center also highlighted that “The number of workers in occupations requiring average to above-average education, training and experience increased from 49 million in 1980 to 83 million in 2015, or by 68%. This was more than double the 31% increase over the same period in employment, from 50 million to 65 million, in jobs requiring below-average education, training and experience.”

An article from ERC (http://dtn.fm/k5jMW) highlights the top 7 trends in employee training and development for 2016, two of which were the continued growth of employee training and the fact that companies that perform better also spend more on training their teams. ProBility Media Corp. (OTCQB: PBYA) recognizes the gap in the training and certification market and is disrupting it by building the first full-service training and career advancement brand specifically for the skilled trades.

ProBility Media Corp. is a provider of training and education content to customers in the skilled trades industries. Historically, high quality training has only been available to enterprise-level companies, however, PBYA offers them to everyone, from trades people to small businesses and enterprise level corporations. PBYA offers consistent, high-quality online training to individuals, from high school graduation to career placement, and it is preparing the workforce for excellence.

ProBility Media offers its services through multiple divisions, including Brown Technical Media Corp., Brown Technical Publications Inc., 1 Exam Prep LLC, Brown Book Shop, and National Electrical Wholesale. Currently, ProBility is working under a disruptive strategy, acquiring other companies that fit into its sector in order to create synergies that will organically grow its revenue and allow it to provide the best set of educational and training content to all of its clients.

For more information, visit the company’s website at www.ProBilityMedia.com

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ChineseInvestors.com, Inc. (OTCQB: CIIX) attended the ‘Invest 2017’ exhibition in Stuttgart, Germany, on April 7-8, 2017, anticipating that the conference would be an opportunity for CIIX to introduce its hemp companies and products to German investors, but CIIX is not alone in seeing the growth opportunities for medical cannabis in that market. CIIX operates a website for Chinese-speaking investors. It has also opened, in the Shanghai Free Trade Area, a store that distributes CBD health oil products to the global Chinese-speaking population.

Germany permits the use of medical marijuana, and it recently further loosened its regulations. Earlier this year, the country legalized medical cannabis, but it has tightly limited its prescriptions to individuals with illnesses such as chronic pain, nausea related to cancer treatments, multiple sclerosis, and epilepsy.

Germany’s Federal Institute for Drugs and Medical Devices (BfArM) has established a special marijuana agency to control the distribution of medical marijuana. The agency will oversee the cultivation and distribution of marijuana in that country. Berlin plans to have its own program by 2019 to grow cannabis at home, and the German government will solicit bids from EU countries to operate the cultivation process. Germany says it will work to ensure that only pharmaceutical grade hemp should reach patients, as noted by Lutz Stroppe, State Secretary of the Federal Ministry of Health.

CIIX sees an opportunity to participate in the German market, and it is also targeting expansion within China and throughout North America and Asia. The ‘Invest 2017’ conference was a chance to showcase the company’s hemp-based product line to the German financial community.

For more information, visit the company’s website at www.ChineseInvestors.com

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MGX Minerals, Inc. (OTC: MGXMF) (CSE: XMG) (FRA: 1MG) may not be spinning straw into gold the way Rumpelstiltskin did, but it’s coming close with a novel technology that promises to produce ‘white gold’, or lithium from petroleum production brine. Its PetroLithium™ technology extracts lithium carbonate from the salt water that accompanies crude oil as it is pumped to the surface. Lithium carbonate represents a major source of lithium used extensively in batteries for electronic devices, and demand for the mineral is set to expand as sales of electric cars increase.

MGX has acquired working interests in over 1.7 million acres of lithium-bearing brine formations throughout North America. This includes massive land positions throughout the Province of Alberta, as well as the Paradox Basin in Utah. In Utah, the company has acquired a dominate land position in the Paradox Basin, where historic wells reported lithium values as high as 730ppm lithium. The company just announced plans to consolidate oil and gas rights within its Lisbon Valley project and permit the petrolithium #1 borehole well.

Lithium first came into use as a medicinal aid in the middle of the nineteenth century. Lithium carbonate was prescribed to dissolve stones in the bladder, while other lithium salts were recommended for use against gout, rheumatism and depression. Lithium carbonate has been used extensively to treat mania associated with bipolar disorder. However, in 1991, after Sony commercialized the lithium-ion battery, the future of lithium was redefined.

Now, the metal has become so lucrative that it’s being touted as ‘white gold’. Lithium carbonate, from which it is isolated, is a white crystalline powder. Its rising value is buoyed by rapidly growing global demand for rechargeable lithium-ion batteries used to power mobile electronic devices and, increasingly, electric vehicles such as the Nissan Leaf and Tesla Model S. All told, the global lithium-ion battery market is forecast to grow at a CAGR of 10.8% and reach $46.21 billion by 2022, according to Allied Market Research (http://dtn.fm/Jjl8r).

At present, though, as a supplier of lithium, the U.S. looks likely to be left out. Global production of lithium comes mainly from Australia (36%) and Chile (36%), with supplies from China (14%), Argentina (8%), Zimbabwe (3%), Portugal (2%) and Brazil (1%) making up the balance, according to data provided by Australian mining company Dakota Minerals (http://dtn.fm/M4djJ). Notably, the U.S. is absent from that list. The only viable U.S. lithium operation is the Silver Peak mine owned by chemical giant Albemarle in Clayton Valley, Nevada. The dearth of domestic lithium mining operations, consequently, presents a great opportunity for MGX.

MGX’s patent-pending PetroLithium™ technology, being developed in collaboration with PurLucid Treatment Solutions (http://dtn.fm/B83d8), extracts lithium carbonate from the brine associated with petroleum deposits while also treating the resulting wastewater for reuse as clean water.

Much of the petroleum and natural gas found in the U.S. was created in the Earth’s crust at the site of ancient seas by the decay of sea life. As a result, these shale, petroleum and gas deposits often occur in aquifers containing brine (salt water).

The company recently reported a major advancement in the development of its filtration and extraction technology (http://dtn.fm/YZlI9) after PurLucid successfully upgraded petrolithium brine from one of the company’s largest assets – the Sturgeon Lake Petro Lithium Project in Alberta, Canada (http://dtn.fm/nT6Tv). By using a new design process that concentrates lithium while removing contaminants, PurLucid was able to upgrade brine from a concentration of 67mg/L Li to 1600mg/L Li during the filtration and pre-treatment stage of the extraction process.

Extracting lithium from petroleum brine is also faster and less costly than conventional methods, like the solar evaporation used at Silver Peak by Albemarle. In the recovery process specifically designed for the highly-mineralized brine associated with petroleum, lithium brine evaporation times are expected to fall to less than one day, while traditional solar evaporation techniques take up to 18 months. This is technology that could revolutionize the energy sector.

For more information, visit the company’s website at www.MGXMinerals.com

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Moxian, Inc. (NASDAQ: MOXC), on March 17, 2017, filed a form S-3 with the SEC (http://nnw.fm/wgv8G), using a ‘shelf’ registration process, for its securities, with an aggregate initial offering price of up to $50 million. These future offerings could be made from time to time, in one or more offerings. Moxian is in the O2O business in China, providing an online platform for small- and medium-sized enterprises (SMEs) with brick-and-mortar stores to compete online, interact with existing customers, and obtain new customers. At the same time, it offers an app to consumer users.

Moxian is a high technology firm which is transitioning away from non-paid beta platforms to paid Moxian+ for its 31,600 SME clients. It will offer them a comprehensive suite of paid online services. The company will also offer its 300,000+ consumer base the Moxian+ User app. Moxian’s revenue streams come from premium subscription services, 3-5% payments on transactions through its platform, mobile advertising and distribution license fees. The company is based in Shenzhen, China, and it is expanding into Shanghai and Guangzhou.

In November 2016, the company was uplisted to NASDAQ after raising $8.5 million net in a public equity offering. Future offerings described in the SEC S-3 filing can involve any combination of securities, including Moxian common shares, senior debt, subordinated debt, warrants, debt securities, or other securities. No new offering is effective yet.

Moxian intends to use the proceeds from these future offerings for general corporate purposes. The precise use would be determined at a future date, based upon funding requirements and the cost of capital, and they would be detailed in a future prospectus supplement for a specific offering, the company said.

For more information, visit www.Moxian.com

Today, AIDS is not the bulletproof killer it appeared to be in the 1980s. Current treatments for those infected by the human immunodeficiency virus (HIV), known collectively as Highly Active Antiretroviral Therapy (HAART), have not destroyed the beast, but they have certainly tamed it. Although the infection still claims thousands of lives every year, for the majority of HIV-positive patients it is now a controllable chronic condition.

Yet, while significantly decreasing mortality, HAART is plagued with complications that run the gamut from issues of toxicity and resistance, to patient compliance and adherence to treatment regimens. Nevertheless, PRO 140 from CytoDyn Inc. (OTCQB: CYDY) holds the promise of resolving those issues. PRO 140 is a humanized monoclonal antibody for HIV treatment that, in trials, has shown no serious side effects and hardly any toxicity in over 200 patients.

HAART, in use since 1996, is a combination of different classes of medications that is prescribed based on such factors as the patient’s viral load (how much virus is in the blood), the particular strain of the virus, the CD4+ cell count, and other considerations, and it is designed to slow the rate at which the HIV makes copies of itself. The HIV life cycle, or replication process, takes place in seven stages and particular drugs interfere with the process by attacking one of those stages. HAART, being a ‘cocktail’ of drugs, attacks on several fronts at different stages in the HIV development process.

Various HAART regimens are currently recommended by the U.S. National Institutes of Health (http://nnw.fm/p2iPW). However, because HAART cannot rid the body of HIV, it must be taken every day for life, and that is a tall order for most patients. Consequently, one flaw of HAART is a lack of ‘medication adherence’, or patients not taking HIV medication every day and as exactly as prescribed.

A common reason for this failure to follow doctor’s order is that the drugs used in HAART can be intensely toxic, to the point of being life threatening, with the prescription, in some cases, being just as bad as the malady. Drug resistance further complicates HIV regimens, although, since HAART is a mix of drugs, there is usually less chance of patients developing resistance.

Unlike HAART, which works to slow HIV replication by inhibiting viral enzymes within cells already affected by HIV, a new class of drugs, known as viral entry inhibitors, is being developed to protect healthy cells from HIV infection by blocking early steps in the viral life cycle. PRO 140 works by attaching to the same portion of the CCR5 co-receptor to which HIV normally binds and by blocking the HIV from attaching to the CCR5 co-receptor, thus denying the virus entry.

This mechanism offers distinct advantages over HAART. The normal function of CCR5 is to bind chemokines, or molecules that regulate inflammation. Other HIV drugs that target CCR5 interact with the pocket of the receptor and thereby inhibit binding of both HIV and chemokines, which may have a number of adverse consequences because of the disruption of the chemokine inflammatory response. However, PRO 140 blocks HIV, yet permits normal chemokine binding, potentially leading to less side effects.

Early clinical testing indicates that PRO 140’s half-life contributes to the masking of CCR5 receptors for up to two months. Thus, infrequent dosing with PRO 140 may be possible compared to small molecule drugs, which require daily dosing.

In addition, being an antibody and not a synthetic drug means that PRO 140 will likely (as it has demonstrated in past clinical trials) have fewer issues with toxicity. In addition, previous short- and long-term trials (as long as 2.5 years) have shown that PRO 140 is less likely to induce the development of resistant viruses.

Last December, CytoDyn Inc. announced that several patients had been treated in the first Phase III clinical trial with PRO 140 as a single-agent maintenance therapy in virally suppressed subjects with HIV. PRO 140 is considered one of the most advanced experimental monoclonal antibodies for HIV treatment and has been used in more than 140 HIV-infected subjects in placebo-controlled and open label FDA-approved clinical trials. The drug has been the subject of seven clinical trials, each demonstrating efficacy by significantly reducing or controlling HIV viral load in human test subjects, and it has been designated a “fast track” product by the FDA.

In January, CytoDyn filed a request for Breakthrough Therapy Designation with the FDA for PRO 140 as a treatment for HIV-1 infection in treatment-experienced patients with virologic failure.

For more information, visit www.CytoDyn.com

From its initial founding in 1946 as a brick-and-mortar bookstore in Houston, Texas, ProBility Media Corp. (OTCQB: PBYA) has taken off, migrating its services online to the cloud. As a result, its revenues have moved up, too. The company’s latest filing reports that net sales for the quarter ended January 31, 2017, rose year-over-year by 24 percent. Now the EdTEch company, aiming to become one of the largest providers of skilled trades education and training in the United States, has begun to explore international expansion to the countries that have adopted U.S.-based codes and training. ProBility Media Corp. continues its strategy to build the first full service training and career advancement brand for the skilled trades.

The company’s latest quarterly (10-Q) filing, for the quarter to January 31, 2017, shows management has been aggressive. Apart from achieving record quarterly sales that crossed the million-dollar mark for the first time, they have been actively engaging in the art of the deal by completing two acquisitions, including the acquisition of One Exam Prep LLC, which offers low-cost yet effective exam prep courses in the construction industry. One Exam Prep, based in Coconut Creek, Florida, owns more than 70 domains related to contractor licensing and continuing education and has created hundreds of courses offered either online or in traditional classroom settings in more than 20 states.

ProBility also signed off on its acquisition of Premier Purchasing and Marketing Alliance LLC. Premier, doing business as National Electrical Wholesale Providers (NEWP), services electrical wholesalers throughout the United States with study materials for electricians, including the National Electrical Code. The company provides a complete line of printed reference materials in addition to e-books, downloadable digital formatting and mobile applications to all distributors. NEWP also provides HVAC, plumbing, industrial and residential trade reference materials with online training for product education, certification and current code practices.

NEWP has significant corporate accounts with electrical wholesale conglomerates, making it one of the largest wholesalers of National Electrical Codes in the United States. It services several multibillion-dollar companies such as Consolidated Electrical Distributors and Home Depot, reaching thousands of accounts in locations throughout the United States.

ProBility also signed an exclusive publishing and distribution deal with All Purpose Crane Training (AP), which provides nationwide crane-rigging training and certification that meets OSHA-ANSI requirements. OSHA is the Occupational Safety and Health Administration; ANSI is the American National Standards Institute.

The courses, customized to meet the specific needs of customers, can be taken either at the customer’s site or at AP’s training centers around the country. They include aerial lift operator training, forklift operator certification, crane rigging instructor courses, mobile crane operator certification, crane operator training, overhead crane training, and rigging and signal-person qualification training.

In addition to these major deals, ProBility has entered into two new publishing contracts. The first is with Ralph Dewey, author of the most widely-distributed instrumentation texts in the industry. Titles include The Purdy’s Instrument Handbook, The Purdy’s Instrument Handbook #2, and Dewey’s Troubleshooting Handbook, all of them staples for professionals who operate in instrumentation or related fields. ProBility will also be the exclusive distributor and publisher of the new release of The Purdy’s Instrument Pocket Guide, to be released soon. This guide will include all the highlights from the three handbooks in a pocket-sized edition.

The company’s second contract is with Pat Ginther for his bestselling book, The Sheet Metal Pocket Guide, created for engineers who design in sheet metal and who are looking for the latest techniques and best practices.

ProBility has signaled its rise to the top with an uplisting to the QB Tier of the OTC Markets. To qualify for the listing, a company must demonstrate that it is current in its reporting requirements to the Securities and Exchange Commission and commits to undergo an annual management certification process to verify officers, directors, controlling shareholders and shares outstanding.

ProBility Media Corp. may have taken off, but it hasn’t left transparency behind.

For more information, visit the company’s website at www.ProBilityMedia.com

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One Step Vending Corp. (OTC: KOSK) is focused on growing through acquisitions and cooperative agreements with companies that have potential and capabilities of achieving sustainable growth and rapidly capturing market share. The company provides financing and operational business support while also helping build key growth strategies. Key business sectors actively targeted include food and refreshment services, self-checkout systems and mobile vending machines.

Corporate Refreshment Services (CRS) Micro Markets Inc., a subsidiary of One Step Vending, is a self-checkout retailer that offers a wide range of food and beverages. Regardless if a traditional vending machine or the high-tech micro market is chosen, the location’s patrons enjoy gourmet market deliciousness and quick market convenience.

Mainly targeting the office environment, the micro markets offer a fresh market-grab and go-food concept that doesn’t cost the business anything to host. Each micro market can be customized for any size or look and feature an easy-to-use touch screen interface so anyone can easily shop, scan and pay for their items. Once installed, employees benefit from a diverse menu that includes healthy snacks, real food, classic vending favorites and much more.

The team behind this concept has been committed to staying at the forefront of vending technology for 15 years. By replacing traditional vending machines with micro markets, they experienced up to five times greater revenue in large accounts. Today, the groundwork is laid with unique capabilities and proven execution strategies.

With CRS Micro Markets Inc. setting the example, One Step Vending’s mission is to support thousands of businesses in the realization of their business goals by delivering experiences that enrich and nourish. Fostering a winning network of associates and partners and building mutually loyalty and trust is core to the company’s growth strategy.

For more information, visit the company’s website at www.OneStepVending.com

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Most businesses across numerous industries would agree that the internet has disrupted them in one way or another, either positively or negatively. Some believe the internet has led to technological advancements never seen before that have enabled them to cut costs, keep their information safe, and make certain day-to-day tasks easier. Others have seen the internet lead to an increase in unemployment, more space for security breaches, and a lack of human touch when it comes to interactions with consumers.

But how has the proliferation of the internet disrupted those in the real estate industry? Recent studies (http://dtn.fm/0wF0F) show that real estate agents in the U.S. are still receiving their usual 5% to 6% commission on home sales, and, despite the internet having had a negative impact on many of the middlemen from various industries, the commission that real estate agents receive has increased since the early 2000s. Although many assumed real estate agents would struggle because of the internet, the number of agents has actually grown by more than 50% in the past 20 years.

What many have not realized is that the internet has affected the industry as a whole, but has not affected the ever-growing need for agents. The internet has changed the way agents work and interact with their clients for the better, because, although consumers are doing more of the home buying research online, they still have a big decision to make, and therefore turn to agents and brokers for help. More has also been done by real estate companies in terms of advertising to keep the focus on their agents, for example, Century 21’s “Good Luck, Robots” TV commercial (http://dtn.fm/aDtl9).

eXp World Holdings, Inc. (OTCQB: EXPI) is showing the importance of real estate agents and brokers through a different approach, by embracing technology and using it to leverage the ability of agents. The rapidly growing company (its agent roster is expected to double in this year alone) has been referred to as the “Amazon” of real estate. It’s an agent-owned brokerage that has cut out the need for brick and mortar facilities with the use of the cloud, but without cutting out the much-needed agents that run it. Instead of using the internet to replace its brokers and agents, EXPI is using it as a tool to maximize agent-ownership, and agents love it.

EXPI is the first company to ever use 3D, fully immersive cloud-based tools and techniques that allow agents to meet colleagues, share advice, learn through virtual classes, and build strategies to further grow their businesses. EXPI has created this business model not to cut out the middleman, but to show Americans that relying less on traditional offices and adopting technological advancements offer significant benefits to both business growth and customer satisfaction.

For more information, visit the company’s website at www.eXpWorldHoldings.com

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