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Lexaria Bioscience Corp. (NASDAQ: LEXX): A Review of Its Research Developments

  • Lexaria Bioscience, the global innovator behind DehydraTECH drug delivery technology, has continuously focused on research into its patented technology
  • The company has conducted both in vitro testing and in vivo animal and human testing to evaluate the ability of DehydraTECH to improve the delivery of various APIs (active pharmaceutical ingredients)
  • Lexaria has multiple other studies lined up aimed at building sufficient data to effect meaningful industry and/or regulatory progress and sustainable increases in valuation
As it moves toward national and international implementation and commercialization of its patented DehydraTECH(TM) drug delivery technology, Lexaria Bioscience (NASDAQ: LEXX) is aware of the need to continuously advance its understanding of the technology’s capabilities and potential applications. This informs the company’s long-held commitment to its applied research and development (“R&D”) programs, which are exclusively designed to “reduce future risks of both commercial and regulatory failure by identifying weaknesses as early as possible; and to enhance the likelihood of future commercial and regulatory success by thoroughly understanding strengths and weaknesses, also as early as possible” (https://ibn.fm/RPxts). Lexaria’s DehydraTECH technology combines a lipophilic active pharmaceutical ingredient (“API”) with a carrier particle, then it is dehydrated and finally rendered as a liquid or powder. Through the years, Lexaria has proven that DehydraTECH results in additional improvements, including speed of onset, increased brain absorption, increased bioavailability, and reduced drug administration costs, thanks to extensive research the company has continuously undertaken since 2015. So far, the research journey has involved a series of controlled and well-designed in vitro pre-clinical testing and in vivo animal and human clinical studies, as well as all-encompassing molecular characterization investigations, which have been completed on APIs such as antiviral drugs, cannabinoids, nicotine and nicotine analogs, PDE5 inhibitors and non-steroidal anti-inflammatory drugs (“NSAIDs”). The company’s in vitro pre-clinical test, an absorption study, was performed to investigate unidirectional cannabidiol (“CBD”) permeability using a human epi-intestinal tissue model with multiple formulations in the presence of simulated intestinal fluid. According to Lexaria, the study evidenced a 325% and 499%, on average, in intestinal tissue permeability compared to two control groups. Lexaria has also undertaken extensive clinical research starting in 2016. Multiple independent, well-designed, and controlled human studies conducted between 2016 and 2017, for example, corroborated the results from the in vitro studies. Since then, the company has undertaken numerous other studies evaluating the performance of various APIs processed using the DehydraTECH technology. For instance, Lexaria has investigated DehydraTECH-CBD as a potential treatment for hypertension and heart disease in multiple human studies, DehydraTECH-processed nicotine (animal study), and antivirals. “Performance of total bioabsorption (directly and indirectly through surrogate biomarkers), blood-brain-barrier delivery characteristics, rapidity of onset, consumer appeal, metabolite production (an indication of first-pass liver bypass), and quality of effectiveness have all been quantified,” Lexaria’s website says of the investigation parameters (https://ibn.fm/Ni2J1). Still, Lexaria is unrelenting in its pursuit of comprehensive datasets that would answer many questions the company expects to face from potential commercial partners or regulators and is, in fact, expanding its research. Last month, Lexaria kicked off an animal study to evaluate DehydraTECH-CBD as a potential treatment to inhibit seizure activity (https://ibn.fm/sX6tE), the first in a series of additional planned animal studies tentatively set to commence this year (https://ibn.fm/4as8P). Others include:
  • HOR-A22-1: an animal study to evaluate DehydraTECH’s ability to improve the delivery characteristics of estrogen
  • DEM-A22-1: an efficacy study to investigate DehydraTECH-CBD with and without nicotine for the potential treatment of dementia
  • RHEUM-A22-1: an efficacy study to evaluate the ability of DehydraTECH-CBD to potentially impact the treatment of rheumatoid disease
  • DIAB-A22-1: an efficacy study to investigate DehydraTECH-CBD’s ability to potentially affect the treatment of diabetes
“DehydraTECH is not an EVOLUTION of existing technology – it is a REVOLUTIONARY new drug delivery platform. Expecting entire industries to change overnight to adopt a revolutionary process is not realistic: it takes time, evidence, and a lot of positive results to overcome industry inertia. We have long been hopeful that, before the end of 2022, we will have built sufficient data to effect meaningful industry and/or regulatory progress and sustainable increases in valuation,” Lexaria CEO Chris Bunka wrote in a recent letter to shareholders. And with the planned and ongoing human and animal studies, Lexaria hopes to achieve precisely this. For more information, visit the company’s website at www.LexariaBioscience.com. NOTE TO INVESTORS: The latest news and updates relating to LEXX are available in the company’s newsroom at https://ibn.fm/LEXX

InMed Pharmaceuticals Inc. (NASDAQ: INM) Gaining Advantage on Processing Rare Cannabinoids with the Help of Subsidiary Bay Medica

  • There is an urgent need for large-scale biosynthetic processing that preserves the purity and consistency of cannabinoids
  • Acquired by InMed in October 2021, Bay Medica is a private U.S. firm specializing in the manufacturing and commercialization of rare cannabinoids for the health and wellness sector
  • InMed has two cannabinol formulations currently in development for ocular and dermatological diseases – INM-088 (ocular for glaucoma) and INM-755 (dermatological cream for epidermolysis bullosa)
The global cannabis market increased exponentially after the pandemic hit, and is anticipated to continue its upward trend over the next few years. The market was valued at $20.47 billion in 2020, reporting a growth rate of 50.92% that year. The sector reached $28.66 billion in 2021 and is anticipated to hit $197.74 billion in 2028, expanding at a CAGR of 32.04% (https://ibn.fm/2o10w). The market growth is paired with an increased demand for rare cannabinoids, with research showing that the biosynthesis of rare cannabinoids is projected to reach $25 billion in 2025 and up to $40 billion by 2040 (https://ibn.fm/jBXUs). The problem faced by companies looking to work with rare cannabinoids on an industrial scale is the lack of efficient biosynthetic production methods that can ensure purity and consistency at high levels of production. Many companies find small-scale processing efficient for maintaining purity and consistency, but InMed Pharmaceuticals (NASDAQ: INM), which sees the potential of rare cannabinoids, is looking to scale up their production to commercial levels, and advanced biosynthetic production methods are necessary to ensure purity and consistency at such levels. InMed is a clinical-stage company that is currently developing a pipeline of cannabinoid-based pharmaceutical drug candidates to treat several diseases with high, unmet medical needs. The company’s focus is on rare cannabinoids, many of which have variants that are not yet available in commercial-size quantities, such as cannabidivarin – CBDV and tetrahydrocannabivarin – THCV. The acquisition of Bay Medica in October 2021 has provided an advantage for InMed in the rare cannabinoid biosynthesis industry. Bay Medica is a private U.S. firm specializing in the manufacturing and commercialization of rare cannabinoids for the health and wellness sector and now operates as a subsidiary of InMed. Bay Medica is comprised of a team of key scientists and professionals from large-scale producers, which gives InMed the unique opportunity to use the technology to scale up the rare cannabinoid synthesis production. In a January news release, Shane Johnson, SVP and General Manager of Bay Medica, said the company was delivering on its objective to launch additional rare cannabinoids in early 2022 in response to inbound demand. “By midyear, we expect to have at least four rare cannabinoids available for the health and wellness markets, positioning us as a leading large-scale supplier of high-quality rare cannabinoids in these sectors,” Johnson explained. Evidence suggests that rare cannabinoids may produce exceptional therapeutic value. One of the rare cannabinoids that InMed has been working with is cannabinol (“CBN”). CBN is the active pharmaceutical ingredient (“API”) in two lead programs being pursued by the company for ocular and dermatological diseases. The company’s most advanced compound currently pursued is INM-755, a CBN topical cream under clinical development for treating epidermolysis bullosa (“EB”), a severe genetic skin disorder. InMed is also developing INM-088, an ocular CBN formulation researched for glaucoma treatment. INM-755 commenced a Phase 2 EB study across 13 sites in eight European countries in 2021. For more information, visit the company’s website at www.InMedPharma.com. NOTE TO INVESTORS: The latest news and updates relating to INM are available in the company’s newsroom at https://ibn.fm/INM

Mydecine Innovations Group Inc. (NEO: MYCO) (OTC: MYCOF) (FSE: 0NFA) Provides Business Update, Marking 2021 Achievements

  • In 2021, Mydecine made significant progress in creating and commercializing new treatments for mental health and addiction disorders
  • It also made a noteworthy shift in focus to reducing expenses and increasing efficiencies for continued clinical trials and the expansion of its IP portfolio
  • For 2022, the company plans to build on the progress achieved in 2021
  • With new additions to its board, its conditional IRB approval, and the clinical research it has lined up for the new year, Mydecine is confident that it will meet its anticipated capital markets initiatives for 2022
Founded in 2020, Mydecine Innovations Group (NEO: MYCO) (OTC: MYCOF) (FSE: 0NFA) has pushed the envelope, particularly in innovating both first- and second-generation novel therapeutics for the treatment of unmet needs in mental health and addiction disorders. Over the past couple of years, it has pursued indications including, but not limited to Post-Traumatic Stress Disorder (“PTSD”), addiction and anxiety, and has made significant progress while at it. In 2021 the company made significant strides toward creating and commercializing new treatments for mental health and addiction disorders, and received conditional IRB approval to advance its Phase 2b smoking cessation study, which the company is confident will yield FDA Investigational New Drug (“IND”) approval in Q2 2022 (https://ibn.fm/sv7UB). More importantly, the year marked a significant shift for the company, focusing on reducing its expenses and increasing efficiencies in a bid to continue progressing its clinical trials and expanding its intellectual property (“IP”) portfolio. As of December 31, 2021, Mydecine had $1.5 million in cash and cash equivalents. Additionally, the company secured additional funding for its clinical trials and its IP portfolio expansion projects. Going forward, Mydecine plans to focus on clinical research, particularly Phase 2b of its smoking cessation clinical study, along with drug development, mainly highlighted by its Artificial Intelligence (“AI”) drug discovery program. “Over the last year, our new chemical entity (“NCE”) program has produced multiple patents covering several second-generation novel molecules that we believe will offer significant improvements over classic psilocybin and MDMA,” noted Rob Roscow, the Chief Scientific Officer at Mydecine. “We’re using a modular development approach to our patent strategy, which gives us the flexibility to license, partner or develop our lead drug candidates from our multiple families of NCEs, all wholly owned by Mydecine,” he added. In 2021, the company filed several provisional and full patent applications for novel molecules with the potential to outperform first-generation compounds safely. These applications covered novel MDMA analogs, improved psilocybin, other tryptamines, and potential heart-safe micro-dosing drugs, among others. Its management is confident that these patents will aid in taking the company to the next level in terms of performance and creating value for its shareholders. Mydecine also announced new independent board member appointments, including Gordon Neal, Josephine Wu, Dr. Saeid Babaei, and Dr. Victoria Hale. They bring a wealth of experience in drug development, clinical trials, and technology, and will be integral to the company meeting its anticipated capital markets initiatives for 2022. Mydecine is optimistic about the new year. With great things lined up, from clinical trials to new drug developments, the company is confident that it will help push the industry forward and create incredible value for its shareholders. “I’d like to personally thank our shareholders, board members, and highly dedicated team for enabling Mydecine to reach these significant milestones, and we look forward to another successful year,” noted Josh Bartch, Mydecine’s Chief Executive Officer (“CEO”). For more information, visit the company’s website at www.Mydecine.com. NOTE TO INVESTORS: The latest news and updates relating to MYCOF are available in the company’s newsroom at https://ibn.fm/MYCOF

Advanced Container Technologies Inc. (ACTX) Makes Mark at CannaCon Conference, Strengthens Foothold in Growing Market

  • The company exhibited at the premier event, held March 31–April 1, 2022
  • ACT has worked to strengthen its presence in the cannabis space
  • This strategic positioning comes as the global cannabis packaging market is projected to reach $297.51 billion by 2026
Advanced Container Technologies (OTC: ACTX) recently wrapped up a successful appearance at the CannaCon Conference, showcasing its new product line and strengthening brand awareness. The company exhibited at the premier event, held March 31–April 1, 2022, alongside Grassfire Distro, ACT’s exclusive packaging reseller (https://ibn.fm/WqmI3). Prior to the two-day event, Advanced Container Technologies CEO Doug Heldoorn noted that ACT had experienced “tremendous success” at last year’s CannaCon Conference. “We have an extensive line of new and exciting products that can help cannabis companies maximize profits throughout the ecosystem — from the cultivator to the retailer,” he stated. Since its participation in CannaCon last year, Advanced Container Technologies has worked to strengthen its presence in the cannabis space. Recognizing that safe, quality packaging in the sector is essential, ACT offers an impressive line of products, including an array of options for virtually every type of cannabis and hemp product, branding solutions, controlled environment cultivation systems, lighting, nutrients and a variety of other essential items. Most recently, the company launched its Store ‘n Seal bags, a new line of premium-quality packaging (https://ibn.fm/O4KVM). The new commercial-grade bags are leak proof, odor proof and watertight, and are designed to store vegetables, lettuce, leafy greens and even cannabis safely. The bags, which feature thick 5ml plastic with a resealable zipper across the top, are available in two varieties: a silver bag with a see-through window and a black-out bag. Each bag holds up to two pounds of product. This strategic positioning comes as the global cannabis packaging market is projected to reach $297.51 billion by 2026, with a CAGR of 22.59% (https://ibn.fm/yf57Z). ACT’s quality options aren’t going unnoticed; the company recently reported year-over-year revenues that show a 209% increase over the prior period, and company management expects that trend to continue. “We believe that we are in a stronger position than most of our competitors who are hampered by enormous operating expenses and dwindling growth rates,” says Heldoorn. “With our focus on remaining nimble and keeping costs and operating expenses as low as possible, we are in an excellent position to continue to grow rapidly outperform our competition in many key indicators.” “As the cannabis market continues to become more competitive, it becomes even more important for companies to find new ways to increase profitability,” Heldoorn added. “Our unique product line can help companies grow brands, deepen customer loyalty, and increase profits.” Advanced Container Technologies is in the business of selling and distributing self-contained, automated, indoor “micro-farms” called Grow Pods, along with related equipment and supplies. Additionally, the company designs and sells patented, proprietary medical-grade plastic containers, known as the Medtainer(R), that store and grind pharmaceuticals, herbs, teas and other solids or liquids. For more information, visit the company’s website at www.AdvancedContainerTechnologies.com. NOTE TO INVESTORS: The latest news and updates relating to ACTX are available in the company’s newsroom at https://ibn.fm/ACTX

Energy Fuels Inc. (NYSE American: UUUU) (TSX: EFR) Watching Nuclear-Energy Action on Capitol Hill

 
  • NEI reports strong bipartisan support for nuclear energy throughout the 117th Congress
  • Hallmark pieces of legislation have demonstrated that carbon-free, always-on nuclear power is an indispensable driver of our clean energy future
  • Institute notes that more can be done “to ensure gigawatts of electricity remain on the grid and new reactors are deployed”
Clean energy has become a top priority worldwide, and the U.S. is no exception. House representatives and senators in the nation’s capital have spent plenty of time talking about and voting on energy, including nuclear energy, and many companies, including Energy Fuels Inc. (NYSE American: UUUU) (TSX: EFR), are paying attention to what’s happening in Washington, DC. “There has been strong bipartisan support for nuclear energy throughout the 117th Congress,” reported the Nuclear Energy Institute (“NEI”), the policy organization of the nuclear technologies industry, in a recent blog (https://ibn.fm/evlYU). “Decarbonization efforts and the clean-energy transition have received heightened attention on the Hill, and hallmark pieces of legislation have demonstrated that carbon-free, always-on nuclear power is an indispensable driver of our clean energy future. “In November, Congress passed the bipartisan $1.2 trillion infrastructure package, which featured major investments in nuclear energy,” the article continued. “The bill contained continued funding for the Advanced Reactor Demonstration Program (‘ARDP’), a demonstration program for Regional Clean Hydrogen Hubs, and support for operating nuclear plants at risk of closure.” The blog mentioned the Build Back Better Act, which is currently on the back burner but contains “broadly supported climate provisions [that] include a production tax credit (‘PTC’) for electricity generated by nuclear power plants in operation today, as well as tax credits for all clean electricity technologies, including advanced nuclear and power uprates that begin construction after 2026,” the piece continued. “The bill also includes funding for the development of a domestic high-assay low-enriched uranium (‘HALEU’) supply, a fuel which is essential to the demonstration of advanced reactors, as well as resources to support efforts such as the coal to nuclear transition.” The NEI piece also noted that the importance of nuclear was being acknowledged in other pieces of critical legislation, including the National Defense Authorization Act (“NDAA”), which was passed in December and “recognized the role advanced nuclear will play in both our national security and climate goals. The Department of Defense will work to deploy microreactors, helping to advance these technologies into commercialization so that they can provide clean energy to remote areas.” In addition, the blog called out several smaller, nuclear-specific bills introduced during this Congress. “These sustained, bipartisan efforts to advance nuclear energy signal a push to meet our climate goals, while also providing jobs and stimulating local economies with new nuclear,” the blog stated. Those bills included the American Nuclear Infrastructure Act (“ANIA”); the Advanced Nuclear Deployment Act; the Nuclear Licensing Efficiency Act; the Modernize Nuclear Reactor Environmental Reviews Act; and the Accelerating Nuclear Innovation through Fee Reform Act; the Fission for the Future Act; the Strengthening American Nuclear Competitiveness Act; and an historic budget request for nuclear from the administration in 2021. “While a bipartisan coalition has boldly committed to supporting new nuclear and protecting operating plants, there is more to be done to ensure gigawatts of electricity remain on the grid and new reactors are deployed,” the blog concluded. “Incentivization programs that value carbon-free energy and fund the next generation of climate technologies, such as advanced nuclear, are essential to meeting our climate goals.” A member of the NEI, Energy Fuels is keenly interested in what happens on a federal level. The company operates three of America’s key uranium production centers: the White Mesa Mill in Utah, the Nichols Ranch ISR Project in Wyoming and the Alta Mesa ISR Project in Texas. The White Mesa Mill is the only conventional uranium mill operating in the U.S. today, has a licensed capacity of more than 8 million pounds of U3O8 per year. The mill is also currently in commercial production of the most advanced rare earth element material being produced in the U.S. today. The mill also produces vanadium when market conditions warrant. The Nichols Ranch ISR Project is currently on standby and has a licensed capacity of 2 million pounds of U3O8 per year. The Alta Mesa ISR Project is also currently on standby. In addition to these production facilities, Energy Fuels has one of the largest NI 43-101-compliant uranium resource portfolios in the country, along with several uranium and uranium/vanadium mining projects on standby and in various stages of permitting and development. For more information, visit the company’s website at www.EnergyFuels.com. NOTE TO INVESTORS: The latest news and updates relating to UUUU are available in the company’s newsroom at http://ibn.fm/UUUU

Knightscope, Inc. (NASDAQ: KSCP) Celebrates 9th Anniversary; Enters $100M Stock Purchase Agreement with B. Riley Principal Capital

  • The security robot market was valued at $8.87 billion in 2020 and is expected to grow to $19.77 billion by 2026
  • Knightscope’s autonomous security robots bridge the gap between unmet security needs and the security demands of a rising population
  • The committed equity facility provides Knightscope with the right to sell and issue up to $100 million of its Class A Common Stock
Since the pandemic, an increased need for autonomous technology in the private security and asset protection industries has become apparent, resulting in a growing market for these solutions. The most recent census reported 325 million people living in the United States, but there are only approximately 700,000 local, state, and federal police officers to protect the population – an industry shortage that can be compensated through the implementation of security robots, like the K5 by Knightscope (NASDAQ: KSCP). As technological developments in the industry evolve, security robots are benefited from improved automation and sensor technology capabilities. Development and improvement in neural network technology have given robots the ability to learn over time – improving overall functionality. As a result, the security robot market is constantly expanding, from $8.87 billion in 2020 to an anticipated value of $19.77 billion by 2026, registering a CAGR of close to 14% during the forecast period of 2021-2026 (https://ibn.fm/g3p7F). Knightscope is a Silicon Valley-based company specializing in advanced security technologies and constructing autonomous security robots (“ASRs”) that deter, detect, and report. Knightscope recently met the security needs of a Silicon Valley commercial real estate (“CRE”) twin-tower office complex, deploying its K5 ASR to answer the property manager’s need for a security strategy for the building’s stakeholders (https://ibn.fm/iYWwV). Knightscope’s K5 ASR is a fully autonomous outdoor security robot with over one million hours of logged, commercially operated service with the ability to run 24/7. With indoor and outdoor terrain capabilities, the K5 has a maximum speed of 3 mph, weighs 398 pounds, and measures 36” (L) x 33.5” (W) x 62.5” (H). Integrated with the Knightscope Security Operations Center (“KSOC”), a browser-based user interface, human eyes can use the real-time data for autonomous detection, including:
  • Force Multiplying Physical Deterrence
  • Eye-Level 360-Degree HD Video Streaming and Recording
  • People Detection During Certain Restricted Hours
  • Thermal Anomaly Detection
  • Automatic Signal Detection
  • License Plate Recognition
The K5 is also weatherproof, allowing outdoors operation, even in adverse conditions. The ASR was also created with ramp accessibility in mind. Knightscope is also making it possible for clients to meet their line of ASRs – through the Robot Roadshow. Clients can either visit virtually or schedule a pod visit on the company’s website. Knightscope recently marked its 9th anniversary (April 4) and announced on the occasion that it had entered into a $100 million common stock purchase agreement with B. Riley Principal Capital. The committed equity facility provides Knightscope with the right (without obligation) to sell and issue up to $100 million of its Class A Common Stock over a period of 24 months to B. Riley at its own discretion – more details can be found in the Form 8-K to be filed by Knightscope with the SEC. “I believe about 95% of startups fail, and the odds of starting a company, growing it, and taking it public are likely in the winning-the-lottery type of odds… but we stuck together and did it with the help of all of our partners! Congratulations and many thanks to the entire Knightscope team, our clients, investors, and suppliers,” Knightscope’s chairman and CEO William Santana Li said, commenting on the 9-year milestone for the company (https://ibn.fm/2TJXi). For more information about Knightscope, visit the company’s website at www.Knightscope.com, and if you are considering subscription service you can request a private demonstration of the technology at www.Knightscope.com/demo. NOTE TO INVESTORS: The latest news and updates relating to KSCP are available in the company’s newsroom at https://ibn.fm/KSCP

The Sweet Smell of Trash: EverGen Infrastructure Corp. (TSX.V: EVGN) (OTCQB: EVGIF) Growing Profits and a Dominant Position in Canada’s Renewable Natural Gas Market

  • Through three acquisitions, EverGen Infrastructure Corp. has rapidly emerged as a leading player in the RNG market with its specialization in waste-to-energy
  • EverGen owns the first producing RNG facility in Western Canada and calls municipalities and FortisBC as customers
  • EverGen recently signed an LOI to expand into Alberta through the acquisition of 67% of a RNG project that has already been contracted to supply RNG to FortisBC
To many, a waist-deep heap of rotting food and agricultural waste is just garbage, but to Chase Edgelow, Chief Executive Officer of EverGen Infrastructure (TSX.V: EVGN) (OTCQB: EVGIF), it is a valuable resource and opportunity to generate profits while doing something good for the planet. Less than two years from inception, EverGen, which brands itself as Canada’s Renewable Natural Gas (“RNG”) Infrastructure Platform, has established itself as a pioneer in the RNG market, snapping up several facilities in the process, including penning an LOI for a controlling stake in in a biogas facility in Alberta in March. RNG, a term used to describe biogas upgraded as a substitute for fossil natural gas, is critical to a clean energy future. Produced from any number of feedstocks, including municipal solid waste, livestock, food, and material from digesters at wastewater treatment plants, RNG can be used in many applications, including heating and cooling, electricity generation, and fuel for many different types of vehicles, amongst other things. This, in turn, saves not only on natural resources, but eliminates all the pollution from the extraction and downstream processes. Moreover, using the organic waste as feedstock can have a meaningful impact on the reduction of ozone-damaging methane emissions created through other disposal methods. Infinity Business Insights sees a thriving global RNG market undergoing 42.1% compound annual growth that will take it from $5.3 billion in 2021 to $62.1 billion by 2028. It is with good reason that Canadian companies including Enbridge Inc., ATCO Energy Solutions, and FortisBC have initiatives ongoing in the space. FortisBC’s has a stated target to have at least 15% of its gas supply carbon neutral by 2030. Headquartered in Vancouver, British Columbia and incorporated in May 2020, EverGen has quickly made a name for itself in its mission to own and operate a portfolio of RNG, waste-to-energy, and related infrastructure projects throughout North America.  With an initial focus in Western Canada, the company operates three facilities through its wholly owned B.C.-based subsidiaries: Net Zero Waste Abbotsford Inc. (“NZWA”), Sea to Sky Soils and Composting Inc. (“SSS”) and Fraser Valley Biogas Ltd. (“FVB”). All three companies were acquired by EverGen in a four-month span from December 2020 to April 2021. FVB has the distinction of being the first producing RNG project in Western Canada from its facility in Abbotsford. It also was the first project to produce RNG into FortisBC’s network. The facility combines anaerobic digestion and biogas upgrading to produce RNG, primarily by converting agricultural waste from local dairy farms. EverGen also generates revenue (in fact, historically most of its revenue) through processing inbound organics, yard waste and biosolids into high-quality organic compost under long-term contracts with municipalities. However, the trend towards RNG is accelerating as the push for a circular energy economy gains momentum. In its favor, EverGen has some powerful relationships and customers in municipalities and FortisBC, an electricity and natural gas distribution utility serving approximately 1.2 million British Columbians. In addition to the FVB/FortisBC agreement, the relationship was deepened last April when FortisBC and NZWA agreed to a 20-year offtake agreement. Per the agreement, which was approved by the British Columbia Utilities Commission in October, FortisBC will purchase up to 173,000 gigajoules of RNG annually from NZWA for injection into its natural gas system. The project is expected to convert municipal and commercial organic waste into enough energy to meet the needs of approximately 1,900 residential homes. From this existing platform, EverGen plans to further develop RNG facilities to provide offtake to FortisBC and other creditworthy buyers under long term contracts. With the regulatory path now clear and development and construction ongoing, NZWA expects to be supplying FortisBC with its RNG by early 2023. EverGen, which completed its initial public offering that raised CDN$20.0 million in August, generated CDN$1.94 million in revenue during the third quarter, bringing the total for the first nine months of 2021 to CDN$6.87 million. In March, EverGen took its first step to expand the next province over, executing a letter of intent with Grow the Energy Circle Ltd (“GrowTEC,” the general partner of CKPPQ Farms LP), to acquire a 67% interest in a biogas facility in Alberta. The LOI also stipulates that the two companies will collaborate on developing and expanding the renewable gas output at such facility, a “cornerstone” project allowing EverGen to continue participating in the consolidation and growth of the RNG industry. EverGen has agreed to pay CDN$6.6 million for the controlling interest though CDN$3.3 million in cash and the balance through issuance of 600,000 shares of common stock at a deemed value of CDN$5.50 per share, a 19.8% premium to the price of the stock the day before the LOI was executed. GrowTEC, located on the Perry Family farm near Lethbridge, Alberta, is a multi- faceted bioenergy venture of sustainable agriculture, integrating responsible best practices and renewable energy. The acquisition dovetails perfectly with EverGen’s growth agenda, as GrowTEC is developing a project that include a farm-scale anaerobic digester that converts biodegradable waste into biogas, subsequently upgrading it to RNG. FortisBC is again in the mix, with the utility committed to buying RNG produced at the farm under an offtake agreement. The project is currently in Phase 1, which is expected to be producing 80,000 gigajoules of RNG per annum starting in Q3 2022. Upon the EverGen investment, the two parties will work to increase production to 140,000 gigajoules of RNG annually. “We are thrilled to be partnering with GrowTEC and working with the Perry Family Farm on EverGen’s first project in the Alberta market,” said Edgelow in a press release on the LOI. “As we expand our RNG infrastructure platform, we are focused on investing in truly sustainable operations that contribute to carbon-negative energy production and positively impact climate change initiatives,” he added. EverGen shareholders will be on the lookout for the completion of the transaction, which is expected to happen before summer arrives. For more information, visit the company’s website at www.EvergenInfra.com. NOTE TO INVESTORS: The latest news and updates relating to EVGIF are available in the company’s newsroom at https://ibn.fm/EVGIF

FuelPositive Corp. (TSX.V: NHHH) (OTCQB: NHHHF) Banking on a Decentralized Agriculture Positioning Model for a Better, Healthier Planet

  • Agriculture generates approximately 19-29% of total global greenhouse gas emissions and also has the highest demand for ammonia, at 80% globally
  • This demand for ammonia is contributing to an increase in greenhouse gas emissions, through its production and additional processes
  • FuelPositive seeks to remedy this situation with its on-site green ammonia production technology
  • Through its decentralized agricultural positioning model, the company aims to reduce ammonia’s overall carbon footprint while also empowering farmers by giving them fertilizer and energy independence and control over supply and costs
Experts have noted, with great concern, that the current food production and distribution systems are already at a breaking point. They have cited the need to feed a growing global population as one of the key factors creating tremendous pressure on a structure that, they note, has been pushed to its environmental limits (https://ibn.fm/H3EIb). FuelPositive (TSX.V: NHHH) (OTCQB: NHHHF) recognizes this issue and, through its green ammonia technology, the company is trying to remedy the situation and offer solutions that are not only sustainable but also accessible, even to the ordinary farmer. Over the years, the agricultural sector has dealt with various challenges, from an aging and shrinking workforce to a significant loss of arable land and, more importantly, the potentially disastrous effects of climate change. According to a report from The World Bank, agriculture remains a significant part of the climate problem, generating approximately 19-29% of total global greenhouse gas (“GHS”) emissions (https://ibn.fm/ypSHv). In addition, agriculture is the sector with the highest demand for ammonia, accounting for over 80% globally. Ammonia is integral for adding nitrogen into the soil, an element that is essential for plant growth and plant health. Usually, the nitrogen is depleted by growing crops, prompting farmers to replenish it using ammonia. The issue, however, arises from ammonia production. Typical manufacturing of this product is energy-intensive and centralized, resulting in some of the world’s most concentrated greenhouse gas emissions. Additionally, there is an issue with supply chain interruptions and wild price fluctuations that affects farmers and adds to other processes that only increase the carbon footprint. FuelPositive seeks to remedy the situation with its decentralized agriculture positioning for its green ammonia. For starters, the company’s product aims to give farmers fertilizer and energy independence. With every farm housing a FuelPositive production unit scaled up or down based on its needs, the farmers will produce sufficient ammonia to fertilize their crops and even power their internal combustion engines in their farm equipment, and generators on the farm (https://ibn.fm/qntgM). This opens even more opportunities for farmers, including converting propane and natural gas crop-drying systems to burn green ammonia as a way to realize an exceptional environmental benefit. This decentralized approach eliminates the traditional supply chain, which is wildly unpredictable, both in supply and cost. Farmers will have control over the amount of ammonia and fuel they produce and when it will be available to them. They will be able to plan on a steady price, giving them a chance to increase their margins and improve their livelihoods from their farming activities. In addition, from an environmental standpoint, the unique ammonia production process eliminates reliance on fossil fuels, and the decentralization of the production facilities negates ammonia’s overall carbon footprint, allowing for a healthier planet. FuelPositive is able to help the agricultural sector reduce its overall greenhouse gas emissions while providing more opportunities for farmers to make a decent living from their operations. In addition, through its push for green ammonia and its push for more farmers to access it, the company is creating even more value for its shareholders. For more information, visit the company’s website at www.FuelPositive.com. NOTE TO INVESTORS: The latest news and updates relating to NHHHF are available in the company’s newsroom at https://ibn.fm/NHHHF

Silo Pharma Inc. (SILO) Emerging Leader as Psychedelics ‘on the Cusp of Entering Mainstream Psychiatry’

  • Mainstream acceptance of psychedelics took a “significant leap forward” with study results published in “Nature Medicine”
  • Many say it is only a matter of time before FDA grants approval for psychoactive compounds to be used therapeutically
  • SILO is focused on merging traditional therapeutics with psychedelic research for people suffering from underserved indications
The Psychedelic Revolution Is Coming,” proclaims a “New York Times” article, which notes that as a result, psychiatry may never be the same. This isn’t news for companies such as Silo Pharma (OTCQB: SILO). A developmental stage biopharmaceutical company focused on merging traditional therapeutics with psychedelic research, Silo has long been familiar with the potential of psychedelics. “It’s been a long, strange trip in the four decades since Rick Doblin, a pioneering psychedelics researcher, dropped his first hit of acid in college and decided to dedicate his life to the healing powers of mind-altering compounds,” reported the Times, noting that psilocybin and MDMA are poised to be the hottest new therapeutics since Prozac. “Even as antidrug campaigns led to the criminalization of Ecstasy, LSD and magic mushrooms, and drove most researchers from the field, Dr. Doblin continued his quixotic crusade with financial help from his parents. “Dr. Doblin’s quest to win mainstream acceptance of psychedelics took a significant leap forward on Monday when the journal ‘Nature Medicine’ published the results of his lab’s study on MDMA, the club drug popularly known as Ecstasy and Molly,” the article continued. “The study, the first phase 3 clinical trial conducted with psychedelic-assisted therapy, found that MDMA paired with counseling brought marked relief to patients with severe post-traumatic stress disorder.” The article observed that only a few weeks ago, the “New England Journal of Medicine” also published a study highlighting the benefits of treating depression with psilocybin, the psychoactive ingredient in magic mushrooms. These studies “have excited scientists, psychotherapists and entrepreneurs in the rapidly expanding field of psychedelic medicine. They say it is only a matter of time before the Food and Drug Administration grants approval for psychoactive compounds to be used therapeutically — for MDMA as soon as 2023, followed by psilocybin a year or two later. After decades of demonization and criminalization, psychedelic drugs are on the cusp of entering mainstream psychiatry, with profound implications for a field that in recent decades has seen few pharmacological advancements for the treatment of mental disorders and addiction. The need for new therapeutics has gained greater urgency amid a national epidemic of opioid abuse and suicides.” This urgency aligns with Silo Pharma’s mission identifying assets to license while funding transformative research for the well-being of patients and the healthcare industry. The company focuses specifically on patients suffering from largely underserved indications like post-traumatic stress disorder (“PTSD”), fibromyalgia, Alzheimer’s disease, Parkinson’s disease, and other rare neurological disorders. The company has filed four U.S. provisional patent applications and a pipeline including a research collaboration with Columbia University and UCSF; an investigator-led sponsored study with Maastricht University; an option agreement with the University of Maryland, Baltimore for patented homing peptides targeting rheumatoid arthritis; licensing for a patented novel peptide-guided drug-delivery approach for the treatment of multiple sclerosis; and upfront funding for a licensing deal for its psilocybin cancer therapeutic applications. Silo Pharma is a developmental-stage biopharmaceutical company focused on merging traditional therapeutics with psychedelic research for people suffering from indications such as PTSD, Alzheimer’s, Parkinson’s and other rare neurological disorders. Silo’s mission is to identify assets to license and fund the research that the company believes will be transformative to the well-being of patients and the healthcare industry. For more information, visit the company’s website at www.SiloPharma.com. NOTE TO INVESTORS: The latest news and updates relating to SILO are available in the company’s newsroom at https://ibn.fm/SILO

Sharing Services Global Corp. (SHRG) Travel Company Ideally Positioned as Travel Projected to Increase in 2022

  • TravelAdvisor survey shows demand for travel remains high with majority of respondents likely to travel this year
  • Survey also reports that the average spend per trip for 2022 is estimated to be beyond that of 2019
  • SHRG’s new company will offer tremendous savings, exclusive benefits to its members
Calling 2022 “the year of the travel rebound,” TripAdvisor announced results of a recent survey indicating that traveler intent for this year demonstrates high demand for booking experiences and a willingness to spend more on travel (https://ibn.fm/YL42V). This is great news for Sharing Services Global (OTCQB: SHRG), which last year launched a new travel company, a direct-selling division focused on providing exclusive benefits and first-class discount travel opportunities (https://ibn.fm/Rh3O9). The TripAdvisor report, which was conducted in partnership with Ipsos MORI, indicates how consumers are planning to travel in 2022 and beyond, and how their attitudes toward and plans for travel have changed compared to prepandemic. “While outside factors like COVID-19 variants, international travel rules and staffing shortages still can represent existential threats to traveler behaviors, year-end sentiment and search data show ongoing demand for travel remains high,” a summary of the report stated. “Who benefits from the tourism demand? As travelers spend more, cultural experience providers (tours and attractions), tourism businesses catering to domestic audiences and companies adhering to safety standards will win the hearts and minds of travelers.” The survey, which was conducted in November 2021, included more than 10,000 participants aged 18 to 75 in the United States, United Kingdom, Australia, Singapore and Japan. Respondents were asked about their sentiments regarding their future travel inclinations, when they plan to travel, and what they’re looking for in a trip when they do. Across the five markets, the majority of respondents indicated that they were either very likely or fairly likely to travel for leisure, to travel to visit friends or family, or to travel for business purposes this year. Specifically, the report noted that “respondents in Singapore were the most likely to say they will travel in 2022 at 89%, followed by respondents in the UK at 85%. Australia and the United States fell in the middle of the five markets surveyed, with 79% and 78%, respectively, saying that they are likely to travel for those reasons in 2022. Japanese respondents were the least likely to say they will travel in 2022, with 58% saying that they are likely to do so — still a healthy proportion of people despite being the lowest of the five markets surveyed.” In addition, TripAdvisor reported that the average amount spent per trip for 2022 is estimated to be beyond that of 2019, as travelers look to level up their travel experience. According to Tripadvisor, American travelers are expected to spend 29% more on their average trip in 2022 than they did in 2019, while in Australia, average booking rates are expected to be up by 16% in 2022 against 2019. Singaporean travelers’ booking values are also expected to increase this year. SHRG’s news of its travel company, one of its Hapi Brands subsidiaries, will be ideally positioned to benefit from these upward trends. According to Sharing Services, to differentiate itself from its competitors, the new company will offer its members unfettered access to tremendous savings and exclusive benefits on a level not seen in the industry before. Sharing Services Global Corporation is a publicly traded diversified company dedicated to maximizing shareholder value through the acquisition and development of innovative companies, products and technologies. The Sharing Services combined platform leverages the capabilities and expertise of various companies that market and sell products direct to the consumer. Its primary division includes Elevacity U.S. LLC, the parent company of the Happy Co. and a sales and marketing company based on utilization of independent contractors as the sales force. For more information, visit the company’s websites at www.SHRGInc.com, www.TheHappyCo.com, and www.HapiTravel.com. NOTE TO INVESTORS: The latest news and updates relating to SHRG are available in the company’s newsroom at http://ibn.fm/SHRG

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Nightfood Holdings Inc. (NGTF) Is Forging the Future of Hospitality with AI-powered Automation Across Industries

September 23, 2025

Robotics and automation are no longer futuristic aspirations; they are rapidly reshaping hospitality operations today. Nightfood Holdings (OTCQB: NGTF) is pioneering this transformation with advanced AI-enabled robotic solutions designed to elevate service quality, optimize operational efficiency and enhance guest experience across the hospitality industry. Hospitality has always thrived on prompt, personalized service, but as labor […]

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