• Pacific Software promoting its B2B ecommerce platform in China
• Food supply chain tracked using IBM Hyperledger Blockchain BaaS infrastructure
• Platform will link supply chains to “internet of things”

Whether it’s in the FX market, in precious metals or in foreign trade, fighting market forces is never a good idea, an admonition recently accentuated by a column in the Financial Times (http://ibn.fm/P4vhg). Despite the imposition of tariffs on $250 billion of Chinese imports into the U.S., those imports “rose 13.2 per cent in October (2018) from a year earlier.” Since 2013, China has been the world’s largest trading (imports plus exports) nation. The likelihood is that it will continue in that position for some time to come – a development that Pacific Software, Inc. (OTC: PFSF) is set to capitalize on. The company sported its Latin American connections at the recently concluded Autumn Canton Fair, where it demonstrated its blockchain ecommerce platform to Chinese importers and investors.

The Canton Fair, which ran from October 15 to November 4 this year, is China’s largest trade fair. The Fair presents an opportunity for the 20,000 or so vendors located in and around Guangzhou to display their wares to the 200,000 buyers, investors and other visitors in attendance. On October 31, 2018, Pacific Software’s show-and-tell took center stage, when the company hosted the Fair’s “Latin American Night” as a co-sponsor (http://ibn.fm/Z4Ab7). The event, made possible by soliciting Brazilian companies, local governments and trade associations for sponsorships, allowed the company to demonstrate its B2B e-commerce blockchain platform in an exotic setting. Presentations took place against a backdrop of cuisine and cultural events.

Development of Pacific Software’s multi-lingual ecommerce B2B and B2C trade platform kicked off in August 2018, after Pacific signed a definitive agreement with Cobalt 47 Technologies Ltd. (http://ibn.fm/wMFjD). Cobalt is a spin-off of KBQuest Group, a leading Chinese Microsoft distributor that was named “Microsoft SQL Partner of the Year 2017.” The platform is meant to ease trade between exporters in Brazil and importers in China. However, its design as an overlay to existing international distribution channels means that it could have much wider application. The technology, which will integrate blockchain components, including Pacific’s Agri-Blockchain, is slated for release by year-end.

Development of the PFSF platform will be undertaken using IBM’s Hyperledger Blockchain “Backend as a Service” (BaaS) infrastructure The IBM BaaS platform has the capability to record, store and track a range of digital product information, including farm origination details, batch numbers, factory and processing data, expiration dates, storage temperatures and shipping details.

Pacific Software is touting the benefits of its blockchain trade platform in smoothing the passage of Brazil’s substantial beef exports to China (mostly Hong Kong), presently running at a rate of about $5 billion per annum. The platform will improve transparency and trust with regard to origin, product quality and product safety and allow food contamination to be more easily detected by tracing the exact source. This will reduce costs tremendously. Under present systems, large quantities of both good food and bad are recalled and destroyed, because it is difficult to pinpoint the precise origin of an outbreak of Escherichia coli (E. coli), Salmonella enteritidis or some other contaminant. In addition, it could save lives. Every year, around 420,000 people die due to food contaminated by bacteria, chemicals, viruses, parasites and toxins.

Pacific’s B2B blockchain platform will also incorporate the capability to accept data from a variety of devices connected to the internet, such as barcode and RFID readers. Its ability to link to the “Internet of Things” will increase reliability and response time, making supply chains a great deal safer.

For more information, visit the company’s website at www.PacificSoftwareInc.com

• Advance of cannabis legalization efforts in Canada and the United States bode well for cannabis industry
• Cannabis Strategic Ventures focused on incubating enterprising new talent and, now, cultivating cannabis product
• Cannabis industry expected to see $32 billion in annual trade within next five years

Canada’s completion of its efforts to legalize cannabis for a full range of uses last month, coinciding with a few U.S. state votes on potential uses of cannabis this month, highlights the advancing popularity of adopting the plant for widespread commercialization, and Cannabis Strategic Ventures, Inc. (OTC: NUGS) is helping to foster serious businesses that want to be a part of this emerging, powerful market.

Despite marijuana’s long cultural association with dopey behavior and decreased intelligence, the cannabis plant has transformed its image in recent years to one of a calming product similar to beer that can be consumed socially, even by progressive and upscale crowds. This is nowhere more apparent than in Canada, for which October marked a line of demarcation as a variety of adult recreational uses of the drug became legal on a national scale (http://ibn.fm/yzrdd).

The United States’ mid-term elections provided the potential for an increasing number of recreational-use states, as well as growth in the somewhat less controversial medicinal and wellness use arena. Nine states and Washington, D.C. currently allow recreational marijuana use despite ongoing federal prohibition, and the vote in Michigan and North Dakota on its acceptance created the potential for legal recreational use among a quarter of the U.S. population (http://ibn.fm/Lbgh2). Meanwhile, two other states’ votes on medicinal uses of marijuana and its non-druggy hemp sibling created the potential for that use case to become legal in more than half of U.S. states.

Cannabis industry incubator Cannabis Strategic Ventures has taken the measure of the plant’s growing potential and is building a worldwide portfolio of companies in the startup and growth stages that can benefit from Cannabis Strategic Ventures’ resources and expertise while allowing investors a place to jump into the emerging market.

In late October, the company announced that it is preparing to add to its product line by entering the cannabis cultivation arena (http://ibn.fm/UNgpm) through acquisitions, beginning in California.

“Currently, the Cannabis Strategic Ventures team is targeting several locations in excess of 200,000+ square feet that have existing cultivation infrastructures in place, which will allow us to move into cultivation very quickly,” company CEO Simon Yu stated in a news release about the plans.

The strategy not only provides Cannabis Strategic Ventures a potential source for its subsidiaries’ products; it also allows the company the flexibility it needs to continue acquiring more brands.

All of this posits the company’s increasing fortunes with investors and business partners as it continues to finalize its application for recognition under the U.S. Securities and Exchange Commission to become a fully reporting participant on a national OTC exchange (http://ibn.fm/D25iE).

According to a joint 2018 executive summary authored by Arcview Market Research and BDS Analytics, the demand for legal cannabis is expected to produce revenues of about $32 billion in less than five years, according to a Cannabis Strategic Ventures news release.

“Growth is on the horizon for the cannabis industry as recreational and medical markets continue to expand, and legalization continues to spread across the country,” Yu stated in a news release. “The Cannabis Strategic Ventures team is confident that moving into cannabis cultivation will allow us to significantly expand our revenue base and provide a strong path for continued financial growth.”

For more information, visit the company’s website at www.CannabisStrategic.com

• SeeThruEquity, LLC, in coverage update, projects that ETST will reach $7.1 million in sales in FY2020 as it grows its product line and expands into full spectrum cannabinoid beverages
• ETST’s ‘As Seen On TV’ campaign, with television celebrity Kevin Harrington as spokesperson, is expected to help drive company sales in the CBD market to $2.2 million by FY2019
• Leading factors in forecast growth include company’s targeting of a fast-growing sub-segment of the market in hemp-derived CBD, as well as the expanded retail distribution of its product line, according SeeThruEquity research

Earth Science Tech, Inc. (OTCQB: ETST) is seen by research firm SeeThruEquity as having diverse capabilities that will generate its growth in the rapidly expanding CBD market, which is projected by Hemp Business Journal to reach $2.1 billion by 2020 from $202 million in 2017, with $450 million of that increase coming from hemp-based sources, according to Forbes (http://ibn.fm/y6OGz).

SeeThruEquity sees ETST’s participation in this booming industry, focusing on the hemp-derived segment, as key to it reaching volume of $7.1 million in sales by FY2020. The research report described its diversity, including its line of nutraceuticals and pharmaceuticals, TV campaign and uplisting to the OCTQB market, and calls Harrington a “potential catalyst” for sales (http://ibn.fm/CU1uY).

“ETST appears positioned to compete for its share of this market growth,” the report said, “as the company has established broad distribution for its high purity CBD product line, covering more than 90,000 retail outlets. Moreover, the company’s pipeline remains robust with an upcoming direct-to-consumer campaign with ‘As Seen On TV’ as well as planned pharmaceutical products in coming years, funding permitting.”

ETST is a biotech company based in Doral, Florida, marketing and developing CBD products, as well as dietary supplements for the pharmaceutical and nutraceutical fields. The company is focused on the cannabidiol, pharmaceutical and nutraceutical sectors, as well as the development, through subsidiaries, of medical devices and research. ETST’s goal is to become a world leader in the CBD space.

It is also moving ahead with the development of its Hygee medical device, finalizing an agreement with Groupe Opmedic, Inc. and its Procrea Fertility Laboratories for lab services to detect sexually transmitted infections (STIs) in women using Hygee (http://ibn.fm/T8NDW).

In the CBD market, ETST is in discussions with an organic grower and processor for an exclusive business/supply relationship that could offer the company its outdoor organic industrial hemp plants, mixing, extraction, bottling and packaging on an exclusive basis. The proposed deal would give ETST a consistent industrial hemp source (http://ibn.fm/y6Am1).

ETST holds several wholly owned subsidiaries. Cannabis Therapeutics is an emerging biotechnology company. KannaBidioiD manufactures and distributes in the recreational sector. Earth Science Foundation, Inc. is becoming a non-profit and accepts grants and donations to conduct additional studies. Earth Science Pharmaceutical develops medical diagnostic tools and vaccines. It also formed subsidiary Canno Inno Laboratories Inc., a strategic Montreal, Canada-based company that provides ETST with access to government grants.

For more information, visit the company’s website at www.EarthScienceTech.com

Southern Africa represents excellent unexplored investment opportunities in oil, according to Aziza Project CEO Robert Pyke.

Pyke commented on the situation in Africa after Bloomberg issued a report about the oil boom that has spread across the continent (http://ibn.fm/EA7st). Drilling has intensified in countries from Algeria to Namibia. The recovery in crude oil prices has contributed to the continuation of the exploration process after a hiatus that lasted for years, the article said.

Rich data gathered over the last three years stands as a confirmation of Africa’s potential, Pyke commented. “The uptick in activity across the continent is very exciting. We believe Southern Africa, in particular, to represent an unexplored opportunity. This is supported by rich data gathered over the last three years.”

A U.S. Geological Survey report estimates that there could be at least 319 trillion cubic feet of gas and 41 billion barrels of oil to be discovered in sub-Saharan Africa, the Bloomberg report said.

According to the Aziza CEO, the prospects of significant finds in the region are promising, regardless of the fact that geological properties necessitate an alternative approach to exploration. “Exploration requires alternative approaches due to the geological properties across much of the region, however, the prospect of significant finds is promising,” he explained.

Through the tokenizing of oil and gas assets in the region, it will become easier for both international investors and local communities to benefit from the potential of oil money, Pyke concluded.

Previously, Pyke said that, while Namibia is widely perceived as a remote destination for oil exploration, it features excellent infrastructure like tarmac roads to key ports and road and rail access to the main refineries located in Cape Town and Johannesburg in neighboring South Africa (http://ibn.fm/28CDk).

Through pre-drilling exploration, experts have established the possibility of one 22,000-square kilometer hydrocarbon concession in Namibia reaching 1.6 billion barrels of oil equivalent.

Aziza Project, which issues asset-backed security tokens known as Aziza Coins, recently launched a Security Token Offering aimed at raising $60 million to complete a 10-well drilling program at the Namibian concession. The Aziza Coin is Ethereum blockchain ERC20 compliant, and its value is derived from the assets held by the Aziza Project.

The company owns 20 percent of Africa New Energies, which has rights to the concession and, if the drilling program is successful, could create significant economic value.

For more information, visit the company’s website at www.Aziza.io

• The first medical cannabis incubator and accelerator financing medical cannabis, CBD and hemp companies through a debt facility
• Well-positioned to gain market share in the emerging cannabis market
• Global legal marijuana market projected to be $146.4 billion by 2025
• Pursuing opportunities in emerging markets and the unique market conditions in the cannabis industry enable unique growth for the company
• Robust loan portfolio consisting of diverse, successful players in the cannabis industry
• Actively looking beyond borders and creating global companies with strong fundamentals that are ready for expansion

Redfund Capital Corp. (CSE: LOAN) (OTC: PNNRF) (Frankfurt: O3X4) is a merchant bank focused on providing debt and equity funding in the mid to late stages of a target company’s development and for technologies that are developed and validated by revenues. Redfund’s current focus is on medical cannabis, hemp and cannabidiol (CBD) related and healthcare-related companies.

As the first medical cannabis incubator and accelerator financing medical cannabis, CBD and hemp companies through a debt facility, Redfund is effectively bridging finance gaps and helping revenue-producing medical cannabis-related companies grow and build their valuations without prematurely diluting their equity.

The central components of the company’s business strategy are:

• Establishing the foundation of a loan portfolio that generates revenues through monthly interest income from loans to cover all general and administrative expenses related to day-to-day operations.
• Growing shareholder value by converting all or part of loans and warrants into equity in portfolio clients as clients build their valuations by entering the public markets or becoming the high-priced targets of larger entities.

Redfund was designed by bankers and entrepreneurs possessing years of experience in business, consulting, capital markets, corporate finance and healthcare services. The company is actively looking beyond borders and creating global companies that have strong fundamentals and are ready to expand.

Redfund’s investments are deployed to companies that have demonstrated success in their business but need a capital bridge in order to expand. Redfund’s team of professionals vet every project and analyzes each prospective client’s financials and business plans. Once a project is approved, Redfund’s legal team carefully scrutinizes the collateral used to securitize the individual loans.

The strategy employed by Redfund includes:

• Diversifying investments in Canada and other countries
• Building an international footprint with established national leaders
• Funding new drug delivery systems and helping nutraceuticals become mainstream drugs
• Introducing companies to Canada as a viable option for public listings
• Becoming a premier go-to lender for established companies

The company’s revenue sources include:

• Interest-bearing debt instruments with asset-backed collateral to securitize loans
• Equity kicker of warrants coverage on original loan
• Conversion ability of loan in its entirety
• Advisory fees from contracts for consulting on growth strategies
• Right of first refusal on future financing in each company funded

For more information, visit the company’s website at www.RedfundCapital.com

• Vigorous Chinese effort to diversify trade away from reliance on U.S.
• Ecommerce platform builds bridge between China and Latin America
• Platform boasts multi-lingual B2B and B2C capabilities

The opening, on October 22, of the world’s longest bridge by Chinese President Xi Jinping marked a signal effort to improve trade between mainland China and the rest of the world. The bridge, which, together with link roads, spans 34 miles (55km), connects Hong Kong to Macau and the mainland Chinese city of Zhuhai. Its inauguration follows closely on the launch of another Chinese mega-project: a high-speed rail link between Hong Kong and Guangzhou.

The opening of the rail link in September 2018 was timely. The 124th Autumn Canton Fair kicked off the following month. Pacific Software, Inc. (OTC: PFSF) was there, building bridges and putting together links of another kind. The company served as a co-sponsor of the event’s ‘Latin America Night’, a featured event at the Canton Fair. It is presently building a proprietary e-commerce trade platform that holds the promise of developing trade between Latin America and China (http://ibn.fm/v6aeb). It seems that bridges are not always made of concrete and steel.

China is wooing the world, with overtures that have reached the U.S., Europe, Africa and Latin America. With a population of 1.4 billion, its appetite for resources is close to insatiable; this is a country that must trade. Moreover, growing trade tensions with the U.S. are prompting the Chinese to beef up trade with other countries. Chinese companies are now on the lookout for new partners. They will undoubtedly welcome the e-commerce trade platform under development by Pacific Software. The company has commissioned Cobalt 47 Technologies Ltd., a spin-off of KBQuest Group, to construct its multi-lingual e-commerce B2B and B2C trade platform.

The platform is expected to be in production by this month and will integrate blockchain components, including the company’s Agri-Blockchain. The technology, designed to work as an overlay to existing international distribution channels, is meant to facilitate trade between exporters in Brazil and importers in China, but, as may be expected, it has wider application. KBQuest Group, Inc. is a leading Microsoft distributor in China and was named ‘Microsoft SQL Partner of the Year 2017’.

Development of the PFSF platform will be undertaken using IBM’s Hyperledger Blockchain “Backend as a Service” (BaaS) infrastructure. The IBM BaaS platform has the capability to record, store and track a variety of digital product information, such as farm origination details, batch numbers, factory and processing data, expiration dates, storage temperatures and shipping details. It is ideal for tracking the tonnes of beef that makes their way from Brazil to Hong Kong.

The Canton Fair, which ran this year from October 15 to November 4, is the largest trade fair in China. The Fair showcases products manufactured by companies in and around Guangzhou and attracts participants from all over the world. Close to 20,000 vendors and about 200,000 buyers attended this year’s event. The Canton Fair is also an opportunity for local government, NGOs and commercial enterprises to exchange and promote trade, culture, tourism and food.

As a co-sponsor of the Fair’s ‘Latin American Night’ on October 31, 2018, Pacific Software had the opportunity to demonstrate its B2B e-commerce solutions and blockchain system. The company actively promoted this event by soliciting Brazilian companies, local governments and trade associations for sponsorships. Pacific Software worked alongside the delegations in disseminating information on culture and trade. However, the event wasn’t all business. It also featured presentations of food, which guests were invited to sample

For more information, visit the company’s website at www.PacificSoftwareInc.com

• GreenBox is adding strategic partners, customers and employees to prepare for growth
• New applications for GRBX services have already exceeded 2019 goal of $1 billion in annual processing volume
• The company’s proprietary blockchain technology allows processing of secure, real-time cashless transactions
• Earlier this year, GRBX acquired Sky Mids Technologies, boosting its volume and growth capacity

GreenBox POS, LLC (OTC: GRBX) is gearing up for a banner year in 2019, when the company expects to reach its goal of $1 billion in annual payment processing volume. GRBX is aggressively adding strategic partners, growing its customer base and boosting employee headcount in preparation for record growth on the horizon.

“GreenBox will continue to add to its roster of strategic partners in order to achieve the processing bandwidth it needs to support the business of its growing customer base,” Ben Errez, executive vice president of GRBX, stated in a press release. “We have new applications for our services in a total amount that far exceeds our 2019 goal of $1 billion in annual processing volume. As such, we need to grow our bandwidth accordingly.”

The company recently announced that it had initiated a new banking relationship, as well as on-boarding and processing accounts volume of more than $50 million annually. GRBX has the option to boost the processing volume for these accounts alone to $100 million by the second quarter of 2019. GreenBox is also recruiting for careers at all levels in anticipation of the rapid processing volume growth (http://ibn.fm/1giyp).

The company’s rapid growth is driven by market adoption of its proprietary technology, which has GRBX well positioned in multiple rapid growth sectors, including the global payments industry, which is forecast to record revenues of $2.2 trillion as soon as 2020; the financial technology industry, estimated to grow at nearly 55 percent CAGR through 2020; and the global point-of-sale terminals market, which is projected to hit a value of $116 billion by 2025 (http://ibn.fm/R5z9l).

Advanced blockchain technology allows GreenBox to securely process cashless transactions in real-time for all kinds of businesses. Merchants receive payment the moment a transaction occurs. The company’s payment processing solutions provide a highly customizable, end-to-end payment network designed to lower transaction costs, reduce fraud and provide stronger compliance with government regulations. For consumers, the company’s QuickCard e-wallet is a mobile app powered by blockchain technology that allows quick, easy and secure cashless payments.

GreenBox’s TrustGateway technology has proven highly effective in preventing fraud for transactions processed on the company’s payment platform. Because it owns the blockchain payment system in its entirety, GRBX has a competitive advantage in fraud prevention. There have been no successful penetrations of the GreenBox platform’s defensive walls to date, and none of the company’s customers lost money or been otherwise harmed through secure transactions across the GRBX platform.

The acquisition earlier this year of Sky Mids Technologies is a significant factor in the company’s capacity for rapid growth. GRBX absorbed the Sky engineering team, technology and book of transactional business. “Following the Sky acquisition, we will be able to accelerate the pace by which the thousands of new business applications are processed, and the best selected to join our ecosystem and enjoy the benefits of our technology,” Errez noted in a news release (http://ibn.fm/WftDQ).

GreenBox POS uses the company’s proprietary technology to build customized payment solutions for a multitude of industries. GRBX has developed the fastest and safest way to send and process money using blockchain technology and has been awarded five provisional patents. The company develops the following main products: POS (point of sale software and hardware solutions); DEL (delivery app, APIs to POS and PAY); PAY (payment app, providing financial APIs to all other components); and KIOSK (deposit, cash and E-wallet management). GreenBox POS is based in San Diego with offices in Seattle, Las Vegas, and Vancouver, British Columbia.

For more information, visit the company’s website at www.GreenBoxPOS.com

• Supply shortfalls bedevil California cannabis
• NUGS on the lookout for grow facilities with existing infrastructure
• Cultivation capability expected to complement retail and distribution divisions

The decision by enterprising California outfit Cannabis Strategic Ventures, Inc. (OTC: NUGS) to enter the cannabis cultivation space could not have come at a better time (http://ibn.fm/dllEt). Supply in California is struggling to satisfy demand, resulting in a shortage of compliant product statewide. Even though the supply bottleneck is not entirely unexpected given the size of California’s market, which is projected to cross the $5 billion mark by 2019, it has been aggravated by new, tighter regulations that, very likely, resulted in the recall and destruction of product already on the market. As a result, additions to supply like those being planned by NUGS will be welcomed by consumers, who have been beset not only by product shortages, but also by limited choice and high prices (http://ibn.fm/Q3vZP).

Cannabis Strategic Ventures has already embarked on pre-acquisition due diligence for prospective cultivation properties located in states that have legalized cannabis. The company has identified several cannabis grow facilities in California and has begun analyzing these for possible acquisition. It is targeting several locations with areas exceeding 200,000 square feet that have existing cultivation infrastructure in place, since it wants to move into cultivation very quickly. NUGS believes that an involvement in cultivation will allow it to realize synergies that will reduce costs and augment the benefits offered by its retail brands. The acquisition of grow facilities will strengthen the strategy of vertical integration and diversification. NUGS plans to operate in the cannabis HR space, leveraging the institutional expertise of the Worldwide Staffing Group, which it is in talks to acquire. The cannabis staffing services will be under the aegis of subsidiary BudHire.

Through another subsidiary – Pure Applied Sciences (PAS) – NUGS markets the PureOrganix brand. This is a line of high quality concentrate, organic and pure cannabis oils that conform to Current Good Manufacturing Practices (cGMP) and meet FDA guidelines for Active Pharmaceuticals Ingredients (API). PAS has started production of Halo Filters, a patent pending, cannabis smoke filtration pre-roll cone. The Halo Filters line is based on an internally developed filtering technology that utilizes ultra-high quality fibers and proprietary manufacturing methodologies. Halo Filters reduce the harsh taste in cannabis smoke, as well as the levels of harmful chemicals, heavy metals and other toxins, while maintaining optimum taste and cannabinoid levels. Cannabis smoke can contain up to eight times the cyanide, three times the ammonia and two times the nitrous oxide of tobacco smoke.

NUGS has also cut an agreement to acquire the Fitamins CBD brand (http://ibn.fm/QgeZO). Products under the brand consist of vitamin- and hemp-derived CBD formulations, which will be distributed through Fitamins’ network of 600+ wholesalers catering to the Asian-American market. The agreement between the companies calls for Fitamins to produce a proprietary CBD product as part of NUGS’ brand portfolio, initially targeting United States distribution networks and eventually expanding into Asian markets that have legalized CBD products.

NUGS has now completed the acquisition of The Asher House Pet CBD brand, a line of U.S. hemp-derived cannabidiol (CBD) supplements for pets that has been garnering national attention. Increased market share and revenues are expected as NUGS provides the infrastructure to support enhanced marketing programs. With a finger in so many cannabis pies, NUGS is sure to find some that are good to the taste.

For more information, visit the company’s website at www.CannabisStrategic.com

• BriaCell is on its way to developing a personalized, off-the-shelf immunotherapy for advanced breast cancer patients
• Because of the market gap and the demand for such treatments, the development and release of the product could be fast tracked
• BriaCell has obtained excellent results in clinical trials so far as Bria-IMT demonstrates the ability to shrink tumors at multiple sites in patients with advanced breast cancer

BriaCell Therapeutics Corp. (OTCQB: BCTXF) (TSX.V: BCT) is developing the first personalized, off-the-shelf advanced breast cancer immunotherapy option using its proprietary targeted immunotherapy technology, company president and CEO Dr. Bill Williams said in a recent interview with Stock Day’s Everett Jolly (http://ibn.fm/EvrXz).

The biotechnology company focuses its efforts on immuno-oncology and is known for its proprietary targeted immunotherapy technology, which makes it possible to offer off-the-shelf personalized treatments for advanced breast cancer patients. According to Williams, the off-the-shelf personalized treatment that BriaCell is developing will be similar to other forms of personalized immunotherapy that are time consuming and costly to produce due to a complex manufacturing process.

Immunotherapy is on the forefront of the battle against cancer. BriaCell is putting all of its effort and resources into the development of treatment options that are highly effective and safe at the same time, Williams explained.

Currently, BriaCell Therapeutics has two major programs – Bria-IMT and Bria-OTS. Bria-IMT is currently in the clinic, while Bria-OTS is in the process of development, Williams said. Previous clinical testing of Bria-IMT has returned promising results. In a clinical trial for the treatment of advanced breast cancer, Bria-IMT contributed to tumor shrinkage in multiple sites (in patients with metastases). Through additional patient testing, the original observations were confirmed.

The company is in Phase 2a clinical testing of its Bria-IMT in combination with pembrolizumab [KEYTRUDA®; manufactured by Merck & Co., Inc. (NYSE: MRK)]. The combination study is listed on ClinicalTrials.gov as NCT03328026.

Bria-OTS is being developed on the basis of results obtained in the Bria-IMT clinical trials. Through its development, BriaCell Therapeutics will be genetically engineering immunotherapy cell lines which will induce specific immune responses against the cancer. The aim of such therapies is to target breast cancer tumors and induce an immune response in a way that’s personalized to the patient, Williams said. Such tailoring is possible through the use of an HLA allele matching system.

According to Williams, BriaCell plans to communicate with the Food and Drug Administration (FDA) about the design of a pivotal Bria-IMT registration trial in 2019. Following the completion of this step, BriaCell plans to start a registration study in 2020. The final Bria-IMT approval is expected by 2023. The personalized, off-the-shelf version of this therapy (Bria-OTS) is approximately two years behind in schedule in comparison to Bria-IMT.

Patients with advanced breast cancer have an unmet need at the moment, Williams noted. Because of the significant demand, the company’s immunotherapies may qualify for accelerated FDA review.

While other immunotherapies are currently available on the market, some patients have seen a poor response and others have experienced serious side effects. Through the use of targeted therapies like the ones developed by BriaCell, the immune response is generated in a specific way to target solely cancerous cells. Healthy tissue is unaffected, which contributes to the excellent tolerance demonstrated in the clinical trials.

According to Williams, numerous pharmaceutical companies are interested in BriaCell’s developments, and they’re simply waiting for more clinical data. “We have that data now and are just trying to put it into a format that we can share with people who are very scientifically advanced. We should be coming back to them within the next couple of months, hopefully generating some additional excitement,” he said.

For more information, visit the company’s website at www.BriaCell.com

• For three months ended August 31, 2018, core investor relations and subscription sales generated $497,560, or 70 percent of CIIX’s $712,360 total revenue
• Warren Wang, CEO of CIIX, eyes greater FY2019 distribution of industrial hemp-based CBD products, both domestically and in China, for CBD Biotech enterprise
• SeeThruEquity, LLC, in update, sees CIIX as having upside potential if it can achieve renewed traction on investor relations and execute on cannabis and cryptocurrency strategies

ChineseInvestors.com, Inc.’s (OTCQB: CIIX) core businesses of investor relations and subscriptions drove 70 percent of its 1Q19 revenues, the company reported. It also had 70 percent higher YOY sales for its first quarter (http://ibn.fm/niMS4). At the same time, CIIX sees CBD Biotech, its wholly-owned foreign enterprise, delivering higher CBD product distribution in FY2019, both domestically and in China. It also reported an 800 percent increase in product sales led by ChineseHempOil.com, Inc. in 1Q19.

The CBD division, which includes CBD Biotech, Hemp Logic, Inc. and ChineseHempOil.com, Inc. (http://ibn.fm/fQa2J), is expected to deliver greater CBD product distribution due to larger marketing resources supplied by the company and an improved business, regulatory and political landscape in China, the company said. Prior, CIIX had also detailed plans to spin off its CBD division in the future.

CIIX presented at the National Investment Banking Association (NIBA) investment conference held at the Crowne Plaza Times Square hotel in New York City on October 31-November 1. It discussed its first quarter 2019 performance.

Wang of CIIX says that the company recorded sales of $2.35 million for FY2018, the 12 months ended May 31, 2018, up 41 percent compared to the prior year (http://ibn.fm/nO4Hd).

“CBD hemp sales in China continue to be the foundation of our focus. Our subscription services will continue to provide a steady revenue stream along with the new educational services covering the cryptocurrency market.” Wang said in a news release. “With increased marketing resources devoted to our industrial hemp-based CBD products, we anticipate a productive fiscal year 2019.”

CIIX in 1Q19 reported a YOY increase of $90,000 from its subscription revenues. Investor relations and subscriptions represent its business roots. CIIX is a diverse company with an international audience of Chinese-speaking investors. It is active in cryptocurrency education and the cannabis industry.

In an update, SeeThruEquity, LLC projected that CIIX is an investment opportunity with upside potential, if the company can provide renewed traction in its high margin investor relations services business and execute on its initiatives in both cannabis and cryptocurrency (http://ibn.fm/6P9rL).

For more information, visit the company’s website at www.ChineseInvestors.com