• Worldwide mobile payment market expected to grow at a CAGR of 33.8 percent from 2017 to 2023 to a market size of $4.5 trillion
• Net Element ranked in Deloitte’s Technology Fast 500 list as one of North America’s fastest-growing companies in 2018
• Net revenue for Q3 2018 increased 15.7 percent to reach $17.2 million, with overall net revenue for first nine months of 2018 reaching $49.7 million

Global technology and value-added solutions group Net Element, Inc. (NASDAQ: NETE) is answering the call for hassle-free purchase of goods and services as consumers and businesses seek the security and ease of digital and cashless payments. New strategies, such as Net Element’s recent announcement to bundle Netevia Light Point-of-Sale (“POS”) mobile payments acceptance software in PAX A920 and A80 smart terminals developed by PAX Technology, are seen as a robust solution to market demands, a news release notes (http://ibn.fm/PXgRD).

“Mobile payments market is growing rapidly and we are taking advantage of this trend by launching our proprietary software on multiple mobile touch points including PAX Technology smart terminal platform,” Vlad Sadovskiy, president of integrated payments for Net Element, stated in the release. “Our robust application and PAX’s powerful hardware will enable business owners to process payments with greater ease and more flexibility than ever before.”

Allied Market Research reports that the mobile payments market is anticipated to reach a market size of $4.5 trillion by 2023, growing at a compound annual growth rate of 33.8 percent from 2017 to 2023 (http://ibn.fm/nkNaJ). The retail segment currently holds a dominant position in the global payment market and is expected to lead all categories by 2023, the report adds.

The combination of Netevia Light POS application and PAX Technology’s Android-based interactive smart payment terminals offers a flexible, state-of-the-art solution aimed at helping merchants conduct transactions in a seamless, convenient way that also provides a user-friendly experience to the consumer. Netevia Light POS application on Smart Terminals by PAX Technology brings all the functions and payment types of a classic point-of-sale terminal with the addition of:

• An easy setup on an all-in-one platform;
• A fully compliant cloud-based solution with real-time reporting;
• Smart inventory management with tip adjustment, discounts and loyalty management;
• Client management, invoicing and on-screen signature; and
• A complete back office solution via Netevia HQ.

Existing PAX technology clients can download the Netevia Light POS application via the smart terminal by PAX Technology without additional hardware, while United Payments clients have effortless access to the Smart Terminals by PAX Technology, as well. As part of United Payments’ comprehensive offerings, merchants can take advantage of the Unified Payments cash discount program in addition to other innovative programs that help merchants reduce fees and expenses while increasing sales.

Net Element supports electronic payments acceptance in a multi-channel environment, including point-of-sale, e-commerce and mobile devices. The company operates a payments-as-a-service transactional and value-added services platform for small to medium enterprise in the U.S. and selected emerging markets. Internationally, Net Element’s strategy is to leverage its omni-channel platform to deliver flexible offerings to emerging markets with diverse banking, regulatory and demographic conditions. Net Element was ranked as one of the fastest-growing companies in North America on Deloitte’s 2018 Technology Fast 500 (http://ibn.fm/xsTkS) and was listed among the South Florida Business Journal’s 2016 fastest-growing technology companies.

For more information, visit the company’s website at www.NetElement.com

• Recently released Q3 2018 results provide evidence of production capacity enhancement and strengthening of the company’s international position
• To support its growth, The Green Organic Dutchman has also hired a number of reputable senior executives to fill key positions in the management team
• Milestones achieved throughout 2018 have granted the company a positive review from one of the world’s leading global investment banking entities
• Recent passage of the U.S. government’s farm bill legalizes hemp production

Recent company announcements reveal the numerous important milestones that The Green Organic Dutchman Holdings Ltd. (TSX: TGOD) (OTCQX: TGODF), a cannabis-focused research and development company, has managed to fulfill in 2018.

• Through the year, the company continued constructing its Hamilton, Ontario, and Valleyfield, Quebec, facilities. In the third quarter of 2018 alone, TGOD deployed $33 million in capital expenditure for this purpose. The company has also focused on optimizing commercial cultivation at its operational facility in Hamilton. The development of five new strains for placement on both the medical and the recreational markets will soon enable The Green Organic Dutchman to provide customers with consistently reliable services.
• In addition, The Green Organic Dutchman is focusing on the expansion of its international footprint. On October 1, 2018, TGOD finalized the HemPoland acquisition, gaining access to established production and sales of CBD oil and industrial hemp products across Europe (http://ibn.fm/C47Xo).
• Also in October, TGOD announced a strategic joint venture with LLACA Grupo Empresarial to create a 50/50-owned company to enter the medicinal cannabis market in Mexico (http://ibn.fm/13Q0R). The agreement will give The Green Organic Dutchman access to a network of 4,500 pharmacies and 3,100 supermarkets throughout Mexico.
• The company invested in Jamaica, as well, through Epican Medicinals (http://ibn.fm/ZNz1H). Sales are currently being run via its store in Kingston, and further expansion via four additional retail stores is anticipated. The Jamaican expansion is expected to increase production capacity by 14,000 kilograms.

With these improvements, The Green Organic Dutchman is anticipating its annual capacity across Canada and Jamaica to reach 170,000 kilograms. The scalable hemp capacity in Poland will add to the company’s international strategic advantage.

These expansion efforts have created a need for the strengthening of The Green Organic Dutchman team. In October 2018, Sean Bovingdon joined TGOD as the company’s new CFO. Bovigndon has over 30 years of experience in the financial management of both public and private companies (http://ibn.fm/rEL3r).

In November 2018, the company announced new additions to its senior management team in an attempt to fortify marketing and compliance efforts. Emily Demeo was appointed as the company’s marketing brand director and Terry Reid was chosen for the legal and compliance director position. Both experts have significant experience and an excellent reputation in their respective fields.

Because of these strategic milestones, TGOD earned a ‘Buy’ rating from Canaccord Genuity – a top investment bank whose analysts believe that the company deserves a speculative buy rating and a price target of C$7.00 ($5.40), almost double the present value (http://ibn.fm/GoVqv).

The Cannacord Genuity analysis points out that The Green Organic Dutchman differentiates itself from the competition on the basis of its organic production.

A recent survey suggests that 43 percent of Canadian recreational cannabis users prefer organic products over standard options. Based on this information, The Green Organic Dutchman’s production capacity is expected to translate to annual revenue in the range of $1.1 to $1.4 billion.

In addition, the recently announced U.S. passage of a comprehensive farm bill provides for the legalization of hemp production in the U.S., opening the door to even greater growth for the hemp industry in general. With presidential approval and imports being eventually allowed, TGOD could be able to export product from HemPoland into the U.S.

The Green Organic Dutchman is a premium organic cannabis company with operations focusing on the legal medicinal and recreational cannabis markets in Canada, Europe and Latin America. The company follows sustainable, all-natural principles in its cannabis production. All TGOD products are laboratory tested to ensure quality, standardization and safety.

For more information, visit the company’s website at www.TGOD.ca

• Youngevity International offers unique products and a compelling business opportunity
• The company offers an array of products under one corporate entity
• Youngevity has its innovative HempFX product line

A foremost omni-direct lifestyle company, Youngevity International, Inc. (NASDAQ: YGYI) offers products from the top eight selling retail categories. In addition, it offers a fusion of the direct selling business model. The company has a growing line of products coupled with its innovative business opportunity. Youngevity International is based in Chula Vista, California. The company was added to the Russell Microcap Index in June 2018.

Fundamentally, Youngevity International is a virtual global Main Street of products and services under one corporate entity. The company offers products in the health and nutrition, home and family, food and beverage, spa and beauty, fashion, essential oils, photo and innovative services categories. Regarding beverages, Youngevity has its wholly owned subsidiary, CLR Roasters. This subsidiary focuses on green coffee distribution, private-label roasting and the sale of owned brands.

Concerning Youngevity’s direct selling business model, it involves person-to-person selling relationships that comprise a “network of networks.” This model advances e-commerce and the strength of social selling. The company’s products and services undergo distribution through an international network of preferred customers and distributors.

Youngevity provides its direct sellers with its inventive YoungevityGo2 app. This distributor app makes the selling process easier for Youngevity’s representatives. Features of the app include data analytics, social media campaigns, digital flipcharts, customer retention and distributor education, digital magazines and engaging videos. For distributors, Youngevity offers low cost entry in three business categories. These consist of its Business Startup Kit, Business Essentials Kit and Business Builder Kit, as suits each individual’s needs.

Youngevity International is in the midst of its worldwide expansion, which includes manifold product approvals set for market. The company has more than 2,000 SKUs (Stock Keeping Units) that are fostering revenue growth (http://ibn.fm/UPsPN). Additionally, its new technology driven web-platform is driving international growth. This platform features a proprietary web-based acquisitions gateway that enables easy on-boarding of products, distributors and customers.

Furthermore, Youngevity is developing a comprehensive line of proprietary hemp-derived cannabidiol oil products. It is expanding its HempFX line. The company recently launched two new hemp-derived cannabidiol products: HempFX Hydration and Sleep and HempFX Hydration – Pure. Youngevity’s HempFX products are available for purchase at www.HempFX.com.

Steve Wallach, Youngevity’s chief executive officer, said in a recent news release (http://ibn.fm/a841g), “HempFX is an ideal representation of our plant-based approach to product development.” The company’s hemp-derived cannabidiol product line-up includes Uplift, Relax, Soothe and Hydration. HempFX sources its hemp-derived cannabinoid oil in Colorado at registered industrial farms. These farms are tested by the Colorado State Department of Agriculture for state and federal regulation compliance (http://ibn.fm/OgFXk).

Among the Top 100 Global Direct Selling Companies, Youngevity International’s commitment is to aggressive expansion. Its strategy to accomplish this includes organic growth, as well as mergers and acquisitions. Youngevity offers investors opportunities in the high-growth industries of direct selling, premium coffee and hemp-derived cannabidiol oil products.

For more information, visit the company’s website at www.YGYI.com

• The Supreme Cannabis Company’s five-year partnership with KKE Canada will include brand management and cultivation consulting
• Deal marks the international expansion of popular Khalifa Kush premium brand
• Agreement builds on Supreme Cannabis’ development of 342,000-square-foot facility
• Supreme Cannabis’ 7ACRES subsidiary recently received ‘Brand of the Year’ honors from 2018 Canadian Cannabis Awards

Premium cannabis brand The Supreme Cannabis Company Inc. (TSX.V: FIRE) (OTC: SPRWF) (FRA: 53S1) is building on the successes of an expansion and marketing effort that brought in a 229 percent year-over-year sales growth during the past year, thanks largely to its high-quality 7ACRES brand. The company announced this month that it will develop and launch an additional lineup of premium products in conjunction with Khalifa Kush Enterprises Canada ULC (“KKE Canada”).

The products are expected to include pre-rolls, extracts, capsules and cannabis oils to be sold by Supreme Cannabis under the KKE brand, based on KKE’s flagship “Khalifa Kush” strain established in the United States market, according to a December 6 news release (http://ibn.fm/GhqtX).

“With the idea for ‘Kush and Orange Juice’ being created in Toronto, it’s the perfect start for the international expansion of Khalifa Kush. My team and I have spent the past year finding a partner that shares our vision, values and passion for cannabis,” KKE principal Wiz Khalifa stated in the release. “The team at Supreme Cannabis understands the importance of high quality cannabis and how to produce high quality cannabis at scale. I am very excited to be working with them.”

The new premium cannabis brand will be offered in Canada and some additional international markets, excluding the United States. Under the terms of the five-year partnership, KKE Canada will provide Supreme Cannabis with consulting services on brand management and cultivation, including cannabis strain selection and consumer education services.

During the course of the renewable five-year partnership, Supreme Cannabis will have exclusive right to commercialize cannabis products under the KKE brand internationally (excluding the United States) for three years, subject to market approval by KKE and a legal framework in which to operate.

KKE Canada will receive more than 5.7 million common shares of Supreme Cannabis and an initial cash payment of C$1 million, followed by annual royalty payments based on the sale of products developed under the partnership.

“Wiz is a globally-recognized cannabis taste maker and connoisseur,” Supreme Cannabis Founding President John Fowler stated. “KKE has had incredible success in U.S. adult-use markets, establishing a brand that is synonymous with ultra-premium quality, based on world-leading genetics… We’re excited to be working with KKE Canada to build another brand with the same commitment to quality (as 7ACRES) to continue the premiumization of our brand portfolio.”

7ACRES flower is focused on pleasing three primary senses: aroma, visual appeal and flavor, according to Fowler. It is cultivated in a 342,000-square-foot facility that is building toward an annual output of 50,000 kilograms of capacity by the new year. The company has also reached an agreement to acquire communications firm Bayfield Strategy, Inc., which is expected to help with brand marketing (http://ibn.fm/2vzEu). The 2018 Canadian Cannabis Awards presented by Lift & Co. (TSX.V: LIFT) recently honored 7ACRES as the ‘Brand of the Year’ in its fifth annual proceedings (http://ibn.fm/EVXQy).

For more information, visit the company’s website at www.Supreme.ca

• Direct sales industry includes a record 20.5 million involved individuals, promising great potential for entrepreneurs
• Sharing Services, Inc. empowers its team of ‘Elepreneurs’ with mentorship and support
• The company’s Blue Ocean Strategy seeks to set the company apart from the competition

Sharing Services, Inc. (OTCQB: SHRV), a diversified holdings company committed to redefining how entrepreneurs succeed, is reshaping the methodology and strategy inside the direct sales industry.

In an age when many are saying goodbye to the local department store in lieu of more personalized shopping done from the ease of their home computer screens, the direct selling industry promises great potential for entrepreneurs. In 2016, the industry saw a record 20.5 million people involved in direct sales, and that same year’s direct retail sales earnings estimate of $35.54 billion is the second highest in the industry’s history (http://ibn.fm/jkeP4).

Through its Blue Ocean Strategy, Sharing Services, Inc. seeks to redefine the direct selling methodology. Its three pronged approach includes supporting its team of home-based entrepreneurs (called ‘Elepreneurs’) by “utilizing the direct selling channel to generate 100% organic growth,” and cultivating as many new business leaders as possible (http://ibn.fm/8Vq8g). By emphasizing home-based entrepreneurial businesses, Sharing Services, Inc. is creating new factors to its industry that have never been offered, including flexibility and new product offerings, thus innovating the market.

SHRV’s Blue Ocean Strategy alludes to a book by two Harvard Business School professors, titled ‘Blue Ocean Strategy: How to Create Uncontested Market Space and Make Competition Irrelevant’. By improving how business is done in its industry, a company can “swim” away from a bloody “red ocean” to discover a non-competitive ocean, in effect claiming the “waters to itself” (http://ibn.fm/QOKZF). Incidentally, Sharing Services, Inc. is constantly expanding its team of Elepreneurs, as it has added roughly 10,000 independent sales representatives in the last few months alone.

One benefit of direct sales to the customer is a more personalized sales experience. Customers are able to receive “personal demonstration and explanation of products, home delivery,” and a greater emphasis on satisfaction guarantee (http://ibn.fm/RUFGv). Smaller entrepreneurial businesses have a larger investment in their customers’ happiness than do large box stores, so they more often take strides to ensure that the overall buying experience is a positive one to ensure that customers return.

Sharing Services, Inc. embraces this paradigm shift by empowering its entrepreneurs through training and mentorship. It is led by a team of businesspeople with decades of experience. The company’s chairman, Robert Oblon, boasts over 22 years in the online travel industry and many years observing a variety of business models. His experiences observing varying business concepts ultimately led to the company’s emphasis on Elepreneurs. Finding that individuals thrive from positive selling experiences with friendly people willing to add a personalized touch, Oblon encourages his team to consider the role that positive psychology and personal development have in direct sales.

Looking ahead, the company’s growth plan includes international expansion by the end of the fourth quarter of 2018.

For more information, visit the company’s website at www.SHRVInc.com

• REFG’s Go delivers a compliant cashless and digital world for legalized cannabis transactions by dispensaries and merchants; retailers and consumers can sign up for Go online
• REFG is a hemp grower that owns SpeedyGrow, licensed in Colorado; it has established itself as a leader in payment processing by handling some 60 million transactions monthly
• The company’s goal is transactional safety and accuracy; it operates within Financial Crimes Enforcement Network (FinCEN) guidelines and offers a transparent and approved environment

Medical Cannabis Payment Solutions’ (OTC: REFG) ‘Go’ is a processing system which offers cannabis dispensaries, merchants and customers a digital payment program that ensures the safety and accuracy of legalized marijuana transactions (www.PayWithGo.com).

REFG is active in the industry as both a payment processor and hemp grower, as a growing number of U.S. states have legalized cannabis and Canada recently approved its use throughout the country (http://ibn.fm/fsh2N). Medical marijuana is now legal in 33 states plus D.C., and 10 states and D.C. have legalized both medical and recreational marijuana (http://ibn.fm/tzkMf). That bodes well for REFG’s activity in the cannabis industry.

REFG’s Go offers legalized cannabis dispensaries and merchants safety, accuracy and easy online sign-up. It is now available to the entire cannabis market. In addition to creating a cashless environment, Go can handle all payments necessary for a small business retailer, such as payroll and vendor disbursements, accounts payable and any other invoices.

Go is capable of processing cryptocurrency payments. The customer or patient can also pay directly from a bank account without requiring cash. REFG, in addition to processing legalized cannabis transactions through Go, is directly involved in growing and processing hemp. A Nevada-based company, it earlier acquired SpeedyGrow, a Wyoming-based firm licensed to grow and process hemp in Colorado (http://ibn.fm/NNMCi).

For more information, visit the company’s website at www.PayWithGo.com

• Flagship Irgon Lithium Mine Project recently identified additional significant spodumene mineralization
• Global lithium-ion battery market forecast to reach $71 billion by 2025
• Worldwide sales of EVs expected to almost quadruple to 4.5 million units by 2020

An undeniable opportunity exists when referring to the Irgon Lithium Mine Project, wholly owned by Vancouver-based QMC Quantum Minerals Corp. (OTC: QMCQF) (TSX.V: QMC) (FSE: 3LQ). As part of QMC’s ongoing exploration and development of the Irgon Project, located in southern Manitoba’s bountiful Cat Lake-Winnipeg River Pegmatite Field (http://ibn.fm/mDEzR), the company’s geotechnical field crews recently identified additional significant spodumene mineralization. This discovery is a significant one, since spodumene mineralization is known as being the primary source of hard-rock lithium. Pegmatites hosting spodumene mineralization may contain large amounts of lithium and, in addition, can host other rare-element-bearing minerals (http://ibn.fm/Umu8P).

Lithium is the main ingredient in the lithium-ion batteries used for energy storage and power provisioning. The global appetite for electric vehicles and the rise of modern devices that rely on lithium-ion batteries are expected to drive the lithium-ion battery market to reach $71 billion by 2025, according to a report by Research and Markets (http://ibn.fm/orEax). Almost all computer electronics, smartphones, tablets and other consumer electronic devices are powered by the lithium-ion battery; however, an article in Bloomberg states (http://ibn.fm/gTTEr) that it is the electric/hybrid vehicle market that is projected to require massive amounts of lithium. “Benchmark Minerals Intelligence, a research and data firm, projects demand to rise from about 220,000 tonnes of lithium-carbonate equivalent last year to more than 900,000 in 2025 and around 2 million by the early 2030s,” the article reads.

QMC has invested two years exploring the potential of the Irgon Lithium Mine Property and is working toward updating the historic 1950s resource estimate (1.2 MT at 1.51 percent Li2O). Channel sampling on the Irgon Dike returned results of 1.73 percent lithium-oxide over 14 meters (45.9 feet), which are higher than the historical numbers. Sampling elsewhere on additional targets in the area has produced concentrations of over 1.90 percent lithium-oxide and one that returned 2.62 percent (http://ibn.fm/cbqrz).

Hard rock mining of spodumene as a source for lithium has distinct advantages over reaping elemental lithium from brines, since only highly concentrated brines produce lithium economically and the process to extract the lithium is glacial. The company states (http://ibn.fm/cJL9f) that once the initial exploration phase has been completed on hard rock lithium pegmatites, such as at its Irgon Project, hard rock pegmatite deposits are faster to mine and production is more reliable. QMC is nearing the final stage of this exploration phase and approaching the point at which an updated NI 43-101 can be filed, which will likely lead the company closer to its goal of actively mining the Irgon Lithium Mine Property.

For more information, visit the company’s website at www.QMCMinerals.com

• LXRP is putting its growth plan into effect, adding a new corporate controller, a head of its legal division and more office staff; in 2019, it will also be increasing its lab personnel
• As a result of the latest positions created, the company is issuing 240,000 new stock options with an exercise price of $1.06 that will vest as to 80,000 per year until April 15, 2021
• LXRP has a growing IP portfolio of 10 patents granted in the U.S. and Australia; it has filed for more than 50 patents worldwide across 10 patent families

Lexaria Bioscience Corp. (CSE: LXX) (OTCQX: LXRP), a drug delivery platform innovator, has announced aggressive growth plans, including the addition of key personnel, a special focus on its lab R&D activities in 2019 and the issue of new stock options.

It has added a new corporate controller, a head of its legal division and additional office staff. In addition, LXRP anticipates adding more lab personnel next year as it intensifies its R&D activities. As a result of the latest positions created, LXRP is issuing 240,000 new stock options with an exercise price of $1.06 that will vest as to 80,000 per year until April 15, 2021, it announced.

Based in British Columbia, Canada, LXRP is a biotechnology company that out-licenses its disruptive delivery technology that promotes healthier ingestion methods. LXRP holds a patent for oral delivery of all cannabinoids and has a growing IP portfolio. DehydraTECH is its proprietary absorption technology platform.

LXRP has received $110,000 from exercised warrants (http://ibn.fm/9vz2Y). The company has also received for exercise a total of 250,000 previously granted warrants with an exercise price of $0.44. Proceeds will be used for general corporate purposes, the company said. No commissions or placement fees were paid related to the funds received from these warrants. LXRP added that the warrants were exercised by third parties, not officers or directors of the company.

For more information, visit the company’s website at www.LexariaBioscience.com

• The safety of a novel combined advanced breast cancer treatment has proven to be excellent, BriaCell announced at a major breast cancer conference
• The monotherapy (i.e. drug on its own) clinical trial showed positive anti-tumor activity in patients with advanced breast cancer and metastases
• Further information about the efficiency of the Bria-IMT/KEYTRUDA combined treatment will be provided in the first quarter of 2019

Initial data from a combination study of Bria-IMT and KEYTRUDA (pembrolizumab) demonstrated an excellent safety profile, BriaCell Therapeutics Corp. (OTCQB: BCTXF) (TSX.V: BCT) announced at the 2018 San Antonio Breast Cancer Symposium (http://ibn.fm/ehRA0). During the conference, the immuno-oncology focused biotechnology company also presented positive proof of concept data for Bria-IMT as a monotherapy for the treatment of advanced breast cancer.

“The robust biological activity of Bria-IMT demonstrated through the trials is very exciting,” BriaCell’s president and CEO, Dr. William Williams, said in a news release. “The findings also reinforce the product development strategy for Bria-OTS – BriaCell’s off-the-shelf personalized immunotherapy solution.”

Studies so far have demonstrated the ability of Bria-IMT to promote a powerful immune response that causes tumor regression in patients with advanced stage breast cancer. “We are highly confident of our strategy to use Bria-IMT in combination with KEYTRUDA, an approved treatment for multiple cancer indications, and expect synergistic activity of this combination in patients with advanced breast cancer. We look forward to additional clinical data and expect to share details at upcoming scientific meetings,” Dr. Williams added.

Presenting the poster was Saveri Bhattacharya (http://ibn.fm/k4uAG), DO, assistant professor of medical oncology at Thomas Jefferson University (http://ibn.fm/fVi7N), researcher at the NCI-designated Sidney Kimmel Cancer Center (http://ibn.fm/2T9hs) at Jefferson Health (http://ibn.fm/7nxXg) and principal investigator (PI) of the study.

In the combination therapeutic study, five patients were treated with Bria-IMT and Merck & Co., Inc.’s (NYSE: MRK) KEYTRUDA. The combination was tolerated very well, and the study is still ongoing to provide further data on the safety of the therapeutic approach. More information about the efficacy of the combination is to be presented in the first quarter of 2019.

Additionally, examination of Bria-IMT’s efficacy in the treatment of advanced breast cancer is ongoing. The Bria-IMT phase I/IIa monotherapy study involved 23 patients who were very heavily pre-treated (a median of four previous systemic therapy regiments per patient). The treatment with Bria-IMT was well-tolerated, with minor local irritation at the injection site being reported as the most common adverse effect.

More importantly, Bria-IMT contributed to tumor shrinkage in three of the patients. The top respondent previously received seven rounds of chemotherapy and had tumor metastases at various sites. The patient’s three-month follow-up showed shrinkage in all 20 metastatic formations in the lungs. After six months, the response was still maintained. Two other patients also showed tumor reduction. All of the patients with tumor reduction matched Bria-IMT at one or more HLA types, validating BriaCell’s approach to selecting patients most likely to respond (BriaDx). Biological activity was observed in several other of the patients, and there was a noted decrease in circulating cancer-associated cells.

Bria-IMT works by stimulating T-cell activity. T-cells are an important immune response component, and their activation is expected to increase the body’s natural ability to recognize and destroy cancer cells.

BriaCell is also focusing on the development of Bria-OTS – a personalized immunotherapy solution that matches the needs of the patient without a specialized manufacturing process. This personalized treatment is expected to be safe and highly effective while avoiding the high costs of creating personalized treatments for advanced cancer patients. In addition, Bria-OTS is created to produce a selective immune response that’s tailored to the specific needs of the cancer patient. Bria-OTS is expected to cover approximately 90 percent of the patient population.

For more information, visit the company’s website at www.BriaCell.com

• Global legal marijuana market to reach $146.4 billion by 2025
• Aeroponic systems produce higher quality at lower cost
• Green has low-cost aeroponic cannabis cultivation system

The global cannabis market is proving to be a precocious new kid on the block. In 2010, respected Harvard economist Jeffery Miron conservatively estimated the U.S. marijuana market to be around $14 billion. Back then, just 11 states – Arizona, California, Hawaii, Michigan, Montana, Nevada, New Jersey, New Mexico, Rhode Island, Vermont and Washington – had legalized medical marijuana, and no state had legalized adult recreational use. However, in April 2018, a report from Grand View Research estimated that the value of the global legal marijuana market – medical and recreational – would reach $146.4 billion by the end of 2025 (http://ibn.fm/7Ylht). Such growth, if realized, would certainly merit the marker of maturity. As the market grows and competition intensifies, efficiency in cultivation and production methods will be a crucial aspect of the value chain, making cost-effective grow solutions like those offered by Green Hygienics Holdings Inc. (OTC: GRYN) increasingly important.

Green Hygienics is a full-scope, premium cannabis cultivation company targeting the high-end medical and adult-use recreational markets. Its strategy revolves around hygienics, the science of preserving and promoting the health of individuals, communities and the planet. Green Hygienics entered the commercial indoor cultivation industry in 2015 and is currently seeking contracts to build marijuana-growing operations utilizing aeroponics, the optimal method for cultivating cannabis.

Essentially, there are three distinct methods of indoor cultivation. For flowers and shrubs, peat-based soil mixtures for roots are best. For wet-weight produce, such as tomatoes, peppers and cucumbers, hydroponics, where the roots are immersed in nutrient-rich liquids, is ideal. However, for dry-weight produce, such as leafy greens, herbs and cannabis, aeroponics, where the roots hang in air permeated by a mist of nutrients, is best. This is Green Hygienics’ forte. The company has developed expertise in aeroponics, and its proprietary aeroponics cultivation system provides a direct feed to plant roots in an enclosed system. A centralized monitoring system ensures that the right temperature and the optimal mix of nutrients is delivered continuously and consistently to plants. This results in benign growing conditions, superior quality and superior yields.

There are many advantages to aeroponics systems. Since they operate in a controlled, protected environment, they escape attack from pests and contamination from toxic agents. In addition, they typically enable faster growth, higher yields and superior quality; are easily scalable; and provide crops that are easier to harvest. They also reduce labor cost, costs of nutrients, grow area and water requirements. Through Green Hygienics’ earlier acquisition of some very important technology, the company has the capacity to become a low-cost producer. Its production cost per gram is estimated to be under $1, while direct competitors cultivating a higher-end indoor product will generally have costs in the range of $2 to $4.

Green Hygienics is establishing itself as a leader in the advancement of science-driven cannabis cultivation systems with the objective of providing the medical and recreational markets with the best possible product and experience. The company aims to grow by generating revenues from the cultivation and sales of premium grade cannabis and derived products, developing and licensing valuable intellectual property assets, making strategic acquisitions and creating trusted global consumer brands.

For more information, visit the company’s website at www.GreenHygienicsHoldings.com