• Canadian metals supply company Ucore Rare Metals Inc. is focused on establishing North American independence in the production of rare earth elements (“REEs”) vital to modern computerized technologies
• China currently dominates the global market for mining, processing and product creation for REEs, raising concerns that governmental controls over its industries could hamstring supplies Western nations need for everything from cell phones to fighter jet parts
• Ucore is preparing to establish commercial operations for REE refining and processing using the company’s trademarked RapidSX(TM) solution, which has demonstrated significant economical and environmental improvement over the standard SX separation technology
• The company recently announced execution of a tax exemption contract in Louisiana, where it will build the first commercial facility, and the company has selected initial construction contractors to get the process under way

Strategic metals enterprise Ucore Rare Metals (TSX.V: UCU) (OTCQX: UURAF) is wrapping up the year by presenting its shareholders a soft construction launch for work at the Louisiana site where the company will build its important rare earth element (“REE”) processing plant.

Ucore announced on December 12 that Louisiana’s governor has executed the contract that will exempt Ucore from some $8.2 million in projected taxes over the next decade, that construction engineering services and construction contracting services subcontractors have been selected, and that members of the Louisiana site program team have begun the “copy & paste” transition process of adapting the technology tested at Ucore’s Canadian demonstration site to the Louisiana facility.

“The recent trip to Ucore’s Kingston, Ontario, RapidSX(TM) Demo Plant really reinforced the size, scale, and importance to North America of what Ucore is working to accomplish for the electric vehicle industry,” Ralph Hennessy, the director of the Louisiana “England Airpark” site, stated in the company’s news release about the progress (https://ibn.fm/dVOzc). “They have assembled a very capable team to construct their facility at the England Airpark, representing a significant milestone in Louisiana’s pathway to a multi-energy economy.”

Ucore’s “Strategic Metals Complex” (“SMC”) in Louisiana represents the fulfillment of efforts to establish a Western-nation supply chain for REEs that is not dependent on China’s industrial domination in the industry. REEs perform crucial functions in modern computerized technologies.

“Knowing that we have local, regional and state support, coupled with federal support through the U.S. Department of Defense and, most recently, from the Government of Canada truly provides a North American solution as we focus on keeping manufacturing jobs in the United States and Canada,” Ucore VP & Chief Operating Officer Mike Schrider, P.E., stated.

For months, Ucore has been demonstrating the capability of RapidSX(TM) REE processing technology in a head-to-head output challenge against the industry standard for REE solvent extraction (known as CSX, or simply SX) at the test facility in Kingston, Ontario. The SMC in Alexandria, Louisiana, will use RapidSX(TM) to produce REEs at commercial scale, building up to 7,500 metric tons of total rare earth oxide (“TREO”) production from an initial 2,000 metric tons startup.

While China has developed its REE mining and processing industries, similar industries in the Americas and other nations have virtually disappeared during recent decades because of economic factors and pollution concerns. RapidSX(TM) offers an improvement over the standard process for teasing the 17 REE metals out of their host ores — a complex process Ucore is managing with a smaller footprint and less demand for electricity.

“The (standard) rare earths refining process can be very finicky,” University of Arizona’s mining and geological engineering department chief Kray Luxbacker told The Economic Times recently (https://ibn.fm/Ltjng). “There are just so many complex steps.”

Once the Louisiana SMC is operational and receiving feedstock from Western mining operations, Ucore will beginning turning its sights toward building two additional planned SMCs in the United States and Canada. The company also owns a rare earths deposit in Alaska that it may tap to mine REEs itself at some point in the future.

For more information, visit the company’s website at www.Ucore.com.

NOTE TO INVESTORS: The latest news and updates relating to UURAF are available in the company’s newsroom at https://ibn.fm/UURAF

• More than a trillion dollars is being invested in clean-energy technologies worldwide
• Vision Marine Technology’s proprietary powertrains will be the inaugural electric motors installed on the Four Winns H2e Bowrider
• Order for E-Motion(TM) 180E outboard and powertrain systems marks beginning of transformative partnership with Wired Pontoons

The worldwide clean-energy movement is happening at an amazing rate, according to a recent NPR interview, with an estimated $1.7 trillion being invested in related technologies (https://ibn.fm/LxNBh). Vision Marine Technologies (NASDAQ: VMAR), a global leader and innovator within the performance electric recreational boating industry, is pioneering the clean-energy transition on the water, selling 100% electric boats, outboard motors and technology to the marine industry.

“Thing are moving at such an astonishing pace,” reported the NPR piece, which noted that “huge swaths” of the country are turning away from fossil fuels as an energy source and investing in other renewable energy sources. “An astonishing stat was this year, about $1.7 trillion worldwide was going to be invested in clean energy technologies — wind, solar power, electric vehicles, nuclear batteries — compared with $1 trillion on fossil fuels. So the amount of money going into it is just staggering. And we keep seeing these records broken.

“The International Energy Agency, for years, they would put out this forecast of how much wind, how much solar, how many electric vehicles they expect in the coming years,” the report continued. “And every year, it would turn out that they just way underestimated the speed of the transition. So it’s something that’s caught even the experts who study this for a living by surprise.”

Vision Marine Technologies is certainly part of this tide of green-energy transformation. In the last several weeks, the company announced the “landmark” delivery of its E-Motion(TM) Electric Powertrain technology to the production facility of Groupe Beneteau, Four Winns (https://ibn.fm/YqUVH). According to the company, these powertrains will be the inaugural electric motors installed on the Four Winns H2e Bowrider.

Calling the delivery “a strategic move to underscore the dawn of a new era in ecofriendly marine transport,” Vision Marine noted that the Four Winns boats will be showcased at the elite Dusseldorf boat show in Europe in January 2024. Recognized for presenting breakthroughs in the boating world, the show offers an ideal platform to highlight the exceptional capabilities and innovations of the E-Motion(TM) powered boats. After the show, stated the company, the E-Motion(TM) 180E equipped boats will be delivered to their ultimate owner, marking a significant milestone: the first-ever electric boats coming off the Four Winns production line destined for consumer ownership.

“The pioneering efforts of Groupe Beneteau and their dedicated production team in crafting a specialized assembly line for electric boats not only sets the course for the future but also fortifies Four Winns with a distinct advantage against any subsequent boat manufacturer venturing into electrification,” said Vision Marine CEO Alexandre Mongeon.

In addition, Vision Marine announced that it had received an initial purchase order from Wired Pontoons for its proprietary E-Motion(TM) 180E outboard and powertrain systems (https://ibn.fm/hyjJK). The order “marks the beginning of a transformative partnership,” VMAR officials noted, as Wired is committed to respond to the growing marine consumer demand for electric marine propulsion.

Wired has spent the last year extensively testing the performance of its pontoons equipped with Vision Marine’s systems, resulting in this inaugural order. “We are excited to collaborate with Vision Marine, starting with an order of 25 E-Motion systems,” said Wired president Curt Jensen. “Over the past 12 months, we’ve seen a decline in the demand for internal combustion engine pontoons, with our customers increasingly seeking ecofriendly alternatives. After evaluating various options, we found the E-Motion(TM) system to be the ideal fit for our clientele.”

Mongeon noted that the U.S. pontoon market is significant, and pontoon users are prime candidates for the E-Motion(TM) 180E. “Since 2021, several pontoon brands have been testing our systems, and we are honored that Curt Jensen’s Wired Pontoons has joined this pioneering group,” he said.

Vision Marine Technologies is in the business of designing and manufacturing electric outboard powertrain systems and related technologies. The company strives to be a guiding force for change and an ongoing driving factor in fighting the problems associated with waterway pollution by disrupting the traditional boating industry with electric power.

For more information, visit the company’s website at www.VisionMarineTechnologies.com.

NOTE TO INVESTORS: The latest news and updates relating to VMAR are available in the company’s newsroom at https://ibn.fm/VMAR

• U.S. existing home sales have suffered a precipitous decline, driven lower by higher interest rates and a lack of supply
• The Hamptons real estate market has remained largely unscathed, with median home sales prices over 65% higher than those achieved in 2019
• Mountain Top Properties have looked to capitalize on the seaside enclave’s historic popularity through the launch of its dedicated Mountain Top Capital Fund I
• In partnership with Joseph Kelley’s On Site Builder Construction, the fund is looking to raise up to $75 million to construct and sell a range of finished, turnkey properties located across Long Island’s East End

U.S. existing home sales dropped to their lowest level in over 13 years in October, dragged lower by the highest mortgage rates in two decades whilst a dearth of housing supply also barred buyers from entering the market. A large factor behind the drop in property market transactions can be attributed to higher interest rates; the average rate for 30-year fixed-rate mortgages averaged 7.31% towards the end of September, prior to peaking at 7.79% in late October – the highest level since November 2020.

“The combination of high prices, high mortgage rates, and millions of homeowners unwilling to move, given they’ve locked in low rates, has frozen the market,” said Robert Frick, corporate economist at Navy Federal Credit Union in Vienna, Virginia (https://ibn.fm/i0AYg).

Despite moderating trends across much of the United States’ real estate market, the Hamptons has largely emerged unscathed. Historically perceived as a luxury seasonal market, characterized by a significant number of ‘second homes’ and a surfeit of cash buyers, the East End of Long Island has come to be renowned for its property market’s relative immunity to cyclical trends elsewhere in the nation.

Whilst the Covid years of 2020 and 2021 broke all records – in 2020, over $8.1 billion worth of real estate was transacted in the Hamptons, nearly twice the total of the previous year – the area’s property sector has remained relatively stable in its wake.

“[Whilst median home sales prices in the Hamptons have seen] a slight dip  of 7.75% to $1,637,500 for this year — YET — that’s a BIG YET — looking back at our 2019 Mid-Year Report and we see the Median Home Sales Price was $995,000,” remarked Judi Desiderio, CEO of Town & Country Real Estate in reference to the property prices in the popular seaside enclave, which currently trade at an average 65% premium to its pre-Covid averages (https://ibn.fm/aGJcY).

It is this evergreen popularity which Mountain Top Properties (OTC: MTPP), a diversified real estate holding company focused around acquiring, marketing and operating assets through its wholly owned affiliates, have sought to capitalize upon. Group subsidiary, Mountain Top Realty Inc. have sought to gain share within the Hampton’s real-estate market through the provision of finished, turnkey properties – a marked contrast to the Hampton’s historical affinity for one-off, customized home sales.

Through its Mountain Top Capital Fund I, Mountain Top Realty has sought to raise $75 million to acquire, build, renovate and remarket homes in the Hamptons; thus far, the fund has already received debt capital commitments amounting to 70 percent of their anticipated real estate acquisition costs as well as a further 100 percent of the planned construction costs – and will look to deploy $10 million soon to leverage strategic waterfront opportunities within the exclusive enclave.

More critically, Mountain Top Realty has entered partnership with On Site Builder Construction, who will spearhead the design and construction aspects of the ambitious project. Helmed by Hamptons real-estate market stalwart, Joseph Kelley, the real estate firm have designed and built some of the Hamptons’ flagship properties over the past four decades – including the construction of the region’s most expensive properties in 2019 and 2022.

Targeting a minimum ROI of 20 to 30 percent per transaction, Mountain Top Properties eventually anticipates translating its experience and expertise within the Hamptons’ competitive property market to other high-end real estate markets through future dedicated funds.

For more information, visit the company’s website at www.Mountain-Top-Properties.com.

NOTE TO INVESTORS: The latest news and updates relating to MTPP are available in the company’s newsroom at https://ibn.fm/MTPP

• DLMI recently announced that global media leader Marty Pompadur has joined the company as a strategic advisor
• The company is creating a conglomerate with multiple subsidiaries operating in many industries, including television, film, music, entertainment, intellectual property, hospitality, technology, and food and beverage
• DLMI intends to fuel these subsidiaries’ growth, with the aim of eventually spinning them off into their own standalone IPOs once they achieve profitability and self-sufficiency
• The company has brought on board strategic advisors with vast experience in the various industries it is targeting
• DLMI is building a hybrid model that blends traditional securities, such as stock and bonds (and we operate in that public security and stock environment), with SEC-registered security tokens

Diamond Lake Minerals (OTC: DLMI), a multi-strategy company combining its old-school business model, centered around traditional securities like stock and bonds, with new school mechanisms such as security tokens to provide shareholder value, is working to become a conglomerate.

Under the guidance of Michael Reynolds, the company’s President and Director, and Brian J. Esposito, the CEO, DLMI is keen on identifying in multiple industries promising opportunities that it can bring into its fold through acquisitions or buildout from scratch, creating multiple subsidiaries. The company intends to then allocate capital and provide access to advisors, know-how, and other resources to support and fuel the growth of these companies.

“The whole idea is wealth enhancement, wealth preservation for our shareholders, getting these entities to be performant to their maximum capacity, and, with the assistance of our advisors and our great experienced management team that we keep adding to our arsenal, getting these companies to be very profitable and self-sufficient to [then] spin them off into their own standalone IPOs at some point,” shared Esposito during an interview with Proactive’s Steve Darling (https://ibn.fm/WJQak).

DLMI has its sights set on a number of industries, including, but not limited to, television, film, music, entertainment, intellectual property, hospitality, technology, and food and beverage (“FNB”), and is bringing on board advisors with years of experience in these industries. “If you look at the advisors, and more are coming, you will see the industries that we will be heavily participating in; a lot of those are industries they have held exceptional careers in,” explained Esposito in a November Bell2Bell Podcast episode (https://ibn.fm/7WN0J).

For instance, Diamond Lake Minerals recently announced that global media leader Marty Pompadur has joined the company as a strategic advisor. Pompadur, who is looking forward to leveraging his experience to contribute to the company’s continued success, has had an illustrious career in the media and entertainment industry, where he has held both junior and senior roles since transitioning from his law practice in 1960 (https://ibn.fm/pVR4T).

Pompadur’s first role in the media field was at the American Broadcasting Companies, Inc. (“ABC, Inc.”), where he worked until 1977. During this 17-year stint, Pompadur was appointed to the ABC, Inc. Board of Directors, becoming the youngest member ever. After leaving ABC, Pompadur took up the role of president of Ziff Corp. until his departure in 1982. Ziff Corp. was the holding company for both Ziff-Davis Broadcasting Company, which ran six network-affiliated TV stations, and Ziff-Davis Publishing Company, one of the largest publishers of consumer special interest magazines and business publications (https://ibn.fm/0OLGR).

Between 1982 and 2008, Pompadur held leadership roles at RP Companies’ various private and public limited partnerships, which operated TV stations, radio stations, and cable television stations, and News Corporation. He is recognized for advising News Corporation in acquiring the Metromedia TV station group and coming up with the business plan for the Fox Television Network in 1985. Pompadur is now involved in many companies as a board member, advisor, and investor.

“We are honored to welcome Marty Pompadur to Diamond Lake Minerals as a strategic advisor. His remarkable career and unparalleled expertise will be instrumental in guiding our strategic initiatives. Marty’s wealth of experience will undoubtedly play a pivotal role in our mission to achieve sustained growth and value creation,” said Esposito of Pompadur’s addition to the advisory team.

Pompadur joins an experienced group of advisors, including Brandon Fugal, Chairman of Colliers International in Utah and Co-Founder of multiple ventures; Anthony Scaramucci, the Founder and Managing Partner of SkyBridge; Larry Namer, the Founder of E! Entertainment TV and President of Metan Global; Andrew Fromm, the Founder of Fromm Consulting; Raul Leal, the CEO of SH Hotels & Resorts; Michael Malik Sr., a prominent entrepreneur and leader in casino development; and Agnes Budzyn, the Managing Partner of Bluedge Ventures.

Looking ahead and leveraging the guidance of its strategic advisors, DLMI hopes to build a hybrid model that blends traditional securities, such as stock and bonds (and we operate in that public security and stock environment), with SEC-registered security tokens. To that end, the company plans to introduce security token offerings through its private partnership with INX.

Under this arrangement, each of DLMI’s subsidiaries will have a security token offering in the market, enabling the company to raise capital and involve investors who are otherwise wary of digital assets like cryptocurrencies and NFTs, a feat Pompadur lauded, noting, “The company’s innovative approach to digital assets aligns with the dynamic evolution in the industry.”

In addition, for information on the company’s security token SEC-regulated exchange partner INX, and the development of the INX Way, visit https://www.inx.co/inx-ebook/. This free security token bible, written with the SEC on the rollout of security tokens and the future of digital assets, will greatly deepen your understanding of security tokens.

For more information, visit the company’s website at www.DiamondLakeMinerals.com or LinkedIn page at www.LinkedIn.com/company/Diamond-Lake-Minerals/.

NOTE TO INVESTORS: The latest news and updates relating to DLMI are available in the company’s newsroom at https://ibn.fm/DLMI

• A number of U.S. cities are reporting an increase in complaints about more brazen rat populations, prompting officials in New York City and elsewhere to devote greater revenues to control measures
• While many rodent control efforts involve traps and poisons, Arizona-based SenesTech Inc., is successfully marketing a one-of-a-kind non-lethal alternative that focuses on chemically preventing rats from birthing an astronomical number of pups throughout the year
• The company recently rolled out a soft bait fertility control product, adding it to its existing liquid product, opening up the vast professional and consumer rodent control market
• SenesTech also recently closed a public offering that will add $5 million to its balance sheet for further development of fertility control for animal pest populations

Rodent control innovator SenesTech (NASDAQ: SNES) is adding approximately $5 million to its balance sheet that it can use for research and development, capital expenditures, working capital, and general and administrative expenses, as well as potential acquisitions.

SenesTech recently closed a public offering of 3.8 million shares of its common stock and accompanying warrants to help advance its corporate strategies (https://ibn.fm/fXvTU). The company has been in a growth phase that includes the introduction of a soft bait fertility control product.

SenesTech’s Evolve(TM) Soft Bait joins its trademarked liquid ContraPest(R) bait as non-lethal methods of controlling rat populations by limiting the fertility of male and female pests that may carry diseases, damage infrastructure and destroy stored foods.

“We are addressing one of the world’s most challenging problems — rodent control — through a completely different way than has ever been done before, by addressing the root cause of the problem — reproduction,” SenesTech President and CEO Joel Fruendt said during an October interview for the Lytham Partners Fall 2023 Investor Conference (https://ibn.fm/kCcv6). “The existing solutions’ effectiveness, namely poisons that are in the marketplace, are limited by rats’ reproduction rates, resistance and aversion, as well as the enhanced social and political limitations on the use of poison.”

After New York City created its office of “rat czar” (or, director of rodent mitigation) earlier this year to deal with its “public enemy number one” (https://ibn.fm/9hpwo), other cities dealing with infestations have taken note.

Boston’s public 311 service request database has catalogued more than 3,900 rodent-related complaints so far this year about the increasingly brazen behavior of rats, prompting calls to centralize rodent control efforts under one office much like New York’s effort (https://ibn.fm/OMgGV). In Chicago, more than 50,000 such complaints were filed with the city last year (https://ibn.fm/hc8pO). 

SenesTech is offering its products to pest management professionals and directly to consumers through the company’s e-commerce portal and through big box retailers. The contraceptive bait is designed to be easy to use, and attractive to rats so that they continue to consume it, bringing greater results over time (https://ibn.fm/RmLeL).

“We have been consistently growing revenues with an 87 percent CAGR over the past few years,” Fruendt said.

Q3 revenue announced Nov. 9 was $360,000, an increase of 44 percent over $250,000 in Q3 2022. The company’s gross profit margin during the same period was 49 percent, growing from $122,000 in 2022 to $176,000 in 2023 (https://ibn.fm/ORMCH).

For more information, visit the company’s website at www.SenesTech.com.

NOTE TO INVESTORS: The latest news and updates relating to SNES are available in the company’s newsroom at https://ibn.fm/SNES

• Clene, a late clinical-stage biopharmaceutical company, creates clean-surfaced, catalytically active nanocrystals that directly modulate biological systems, including the central nervous system, by improving mitochondrial health
• The company’s lead investigational candidate, CNM-Au8(R), is currently in development as a disease-modifying treatment for people living with specific types of neurodegenerative disorders (“ND”), namely amyotrophic lateral sclerosis (“ALS”), Parkinson’s Disease, and multiple sclerosis (“MS”)
• Neurodegenerative disorders are characterized by neurodegeneration – the progressive loss of neuron structure, neuronal functions, and finally, the neurons themselves
• Nanotherapeutics are in development to stop or reverse neurodegeneration using novel approaches to address the mitochondrial deficits and bioenergetic crises common to these neurodegenerative diseases

Also known simply as nerve cells, neurons are central to most – if not all – of the body’s normal functions, from breathing and talking to eating, thinking, and walking (https://ibn.fm/zWMUR). They support these activities by sending and receiving information between the brain and muscles, and are also responsible for receiving sensory input from the external environment and relaying that information to the brain.

As crucial as neurons are, they are not immortal. Like all other cells in the body, nerve cells undergo apoptosis, which is the programmed process by which body cells die. Apoptosis helps remove surplus, aged, damaged, or unwanted cells. However, in some cases, apoptosis becomes dysregulated, leading to the premature loss of central nervous system cells (https://ibn.fm/DqqvW) as is seen in neurodegeneration.

“Diseases with neurodegeneration as their hallmark feature are collectively termed as neurodegenerative disorders (‘NDs’). The most common NDs include Alzheimer’s disease, Parkinson’s disease, prion disease, amyotrophic lateral sclerosis (‘ALS’), motor neuron disease, Huntington’s disease, spinal muscular atrophy, and spinocerebellar ataxia,” explains a 2022 study (https://ibn.fm/qldhY).

While NDs affect millions worldwide and continue to be a growing concern, their treatment have only utilized small molecule or biologic approaches. More progress is needed as a number of challenges remain, ranging from lack of efficacy to lack of delivery of sufficient amounts of active drug to the brain across the blood brain barrier.

Fortunately, in recent years, nanotechnology has revolutionized the healthcare sector, facilitating the development of nano-sized therapeutic drugs or nanotherapeutics. These nanotherapeutics, whose sizes range between 1 and 100 nm, are positioned as a possible alternative for stopping or reversing neurodegeneration thanks to their unique mechanisms of action and their potential ability to efficiently cross the blood-brain barrier without altering or damaging it.

The therapeutic potential of nanoparticles has piqued the interest of Clene (NASDAQ: CLNN) and its wholly owned subsidiary Clene Nanomedicine, Inc., a late clinical-stage biopharmaceutical company focused on the discovery and development of innovative, life-changing medicines for people with serious and life-threatening diseases. The company has created and refined a proprietary electro-crystallization-method that results in clean-surfaced, catalytically active nanocrystals that directly modulate biological systems, including the central nervous system, by improving mitochondrial health.

“Multiple lines of evidence now point to energetic failure as a key contributor to neurodegenerative disease. Neurons and their associated support cells, in particular oligodendrocytes, are amongst the highest energy-consuming cells in the body: the brain represents only 2% of the human body weight, yet it consumes over 20% of the body’s metabolic energy. As humans age, our cell’s ability to convert food into energy in the form of ATP becomes less efficient. Eventually, the nervous system’s demand for ATP surpasses the cell’s ability to supply it, and as a consequence, neurons begin to fail and subsequently die,” explains the company in its 2022 annual report (https://ibn.fm/QsZVY).

Clene’s preclinical studies have shown that its lead investigational candidate CNM-Au8, an oral suspension of clean-surfaced, catalytically-active gold nanocrystals, crosses the blood-brain barrier and gives the neurons and associated support cells an energetic boost or helps improve energy production and utilization to enhance survival. The preclinical studies eventually transitioned into clinical studies, which have demonstrated promising results.

Recently, the company reported a 75% decreased risk of death, and a statistically significant 52% decreased risk of ALS clinical worsening events (defined as first occurrence of any of the following: death, tracheostomy, assisted ventilation, or feeding tube placement) in ALS clinical trial participants treated with CNM-Au8 following long-term analysis. A separate long-term follow-up analysis also showed that treatment with CNM-Au8 significantly improved survival in ALS patients (https://ibn.fm/Ne9PJ). Because individuals diagnosed with ALS typically live an average of 3-5 years beyond their diagnosis, a drug that has potential to affect lifespan garners great interest, especially if the drug is shown to be safe with minimal side effects. To date, Clene has reported over 500 years of human subject exposure without any serious adverse events attributed to the drug across all its clinical programs.

CNM-Au8 is currently in development as a disease-modifying treatment for people living with ALS, Parkinson’s Disease, and MS. ALS is an ND that affects motor neurons, the neurons in the brain and spinal cord that control breathing and voluntary muscle movements, causing these nerve cells to degenerate and die. Parkinson’s Disease is caused by the death of nerve cells that produce dopamine. These cells are located in the basal ganglia, an area of the brain that controls movement. As a result, Parkinson’s Disease patients experience unintended or uncontrollable movements and difficulty with coordination and balance. MS is a disorder in which the immune system cells attack and eat away at the substance that covers the nerves known as myelin. In MS, multiple neuronal subtypes can be affected by demyelination, and subsequently die as a result of myelin loss. In all of these diseases, studies have shown that mitochondrial dysfunction precedes neuronal death. By targeting mitochondrial function with the innovation of catalytically-active gold nanocrystals, Clene aims to develop a first-in-class drug to address these diseases with few treatment alternatives and significantly high unmet needs.

For more information, visit the company’s website at www.Clene.com.

NOTE TO INVESTORS: The latest news and updates relating to CLNN are available in the company’s newsroom at https://ibn.fm/CLNN

• The CDC estimates 1 out of 36 children in the United States have been diagnosed with Autism Spectrum Disorder – with a therapeutic market potential of $3.42 billion by 2030
• PaxMedica’s mission is to help eliminate, reduce, or modulate the troublesome aspects of ASD, an unmet medical need in the industry
• CEO Howard Weisman shared important updates and achievements in the company’s pipeline, financial outlook, and future vision

In a 2020 report released by the Centers for Disease Control and Prevention (“CDC”), it was estimated that 1 out of 36 children had been diagnosed with autism spectrum disorder (“ASD”) in the United States. While ASD is not uncommon, there are no pharmaceutical treatments approved to treat the disorder, only to manage the symptoms – which creates an unmet need in the industry. The ASD therapeutics market was valued at $1.93 billion in 2022 and is expected to reach $3.42 billion by 2030, growing at a CAGR of 7.9% (https://ibn.fm/RprVv).

It is essential to note that these estimates do not factor in the potential impact of treatments designed to address the core symptoms of ASD.

PaxMedica (NASDAQ: PXMD), a clinical-stage biopharmaceutical company focused on developing novel anti-purinergic therapies (“APTs”) for the treatment of ASD and other serious conditions with intractable neurologic symptoms, is on a mission to help, reduce, and modulate some of the more challenging aspects of ASD. The company hopes to enable people with autism to integrate their behavior with others more successfully and improve their quality of life.

PaxMedica recently released a Fireside Chat video with its Chairman and CEO Howard Weisman. The comprehensive video update shares insights into the company’s recent achievements and advancements – underscoring the commitment to groundbreaking therapies and transformative solutions (https://ibn.fm/5tAEy).

Mr. Weisman covered the following key attributes during the video:

Regulatory Update: Insights from the recent FDA Type-B meeting on October 25th shed light on the regulatory pathway for HAT-PAX-101.

Financial Boost: A successful $7 million public offering, strengthening PaxMedica’s balance sheet and providing a financial platform for production and clinical trial initiatives.

Strategic Acquisition: The acquisition of suramin research assets from Rediscovery Life Sciences (“RLS”), potentially expediting the NDA submission for PAX-101.

Clinical Trials Progress: Updates and insights into future Autism Spectrum Disorder (“ASD”) trials.

Business Efficiency: PaxMedica’s business strategy emphasizes efficiency, production milestones, and key partnerships with organizations like Vox Nova.

Future Vision: PaxMedica’s business strategy, including NDA plans for PAX-101 and potential advancements in autism treatment.

The Fireside Chat is available on the company’s YouTube channel at https://ibn.fm/Yx2R3.

PaxMedica plans to continue into 2024 with the momentum it has gained during the current year. The company is on a promising path to address the unmet medical needs associated with ASD, bringing hope to millions.

For more information, visit the company’s website at www.PaxMedica.com.

NOTE TO INVESTORS: The latest news and updates relating to PXMD are available in the company’s newsroom at https://ibn.fm/PXMD

• GEMXX Corporation is a Las Vegas-based jewelry maker developing its strategic gold metal and ammolite gemstone from a unique mine-to-market product pipeline
• Gold has enjoyed record high prices during a “roaring 2023” run, and price fluctuations surrounding those highs have failed to deter optimism that demand for the precious metal may remain during the coming year
• GEMXX is the only publicly traded ammolite gemstone company in the world, and plans to expand its gemstone and jewelry production by 300 percent next year
• The company reported upbeat earnings and no long-term debt in its recent Q2 financial statement

With the close of its 2023 mining test season, mine-to-market jewelry enterprise GEMXX (OTC: GEMZ) is celebrating positive outcomes from its mine assessment, debt management practices, and revenue operations, as it prepares for further growth in 2024. GEMXX reported upbeat earnings during its Q2 statement published Nov. 21, stating that its account receivables rose from $701,252 to $1.3 million YOY, total assets increased to $20.1 million, and net income grew from $132,842 to $212,526 — all while maintaining no long-term debt (https://ibn.fm/QOuV2). The company is led by an executive team with over 160 years of combined experience in the market, and gold’s continued demand strength has provided GEMXX’s leadership with encouragement as it pursues its long-term strategy.

The company is planning to expand its ammolite gemstone and jewelry production by 300 percent next year, with expectations of supplying $5.5 million worth of ammolite jewelry through GEMXX’s shopping channel division. The ammolite gems are derived from the fossilized shells of ammonites, a group of large, extinct marine nautiluses, and are prized for their iridescent coloration. Alberta is the only place the gemstones are commercially mined, and world-class gem cutters help GEMXX turn them into the distinctive jewelry for which it is becoming known.

GEMXX, unique in that the company draws on its own mining assets for the gold and ammolite gemstones it uses in colorful jewelry, is the only publicly traded ammolite gemstone company in the world, and lately has been exploring the potential of its gold resources as well.

The World Gold Council (“WGC”) continues to remain optimistic about the precious metal’s performance regardless of price fluctuations surrounding recent record highs.

“Heightened geopolitical tensions in a key election year for many major economies, combined with continued central bank buying could provide additional support for gold,” the WGC stated in its Gold Outlook 2024 report published earlier this month (https://ibn.fm/7s2nL).

“There’s no fiscal discipline in the United States. People have gotten used to free money. It’s going to be hard to tighten things up,” giant gold producer Barrick Gold Corp. CEO Mark Bristow added in a recent interview with the Financial Post (https://ibn.fm/7KkE1). “Overall, I feel gold has much more upside than downside risk looking forward.”

The company processed 31,200 cubic yards of gold-bearing ore yielding 0.929 ounces per 100 cubic yards at its 498-acre Snow Creek gold property in 2023 and expects to triple production at the site during the coming year, according to a separate Nov. 7 report (https://ibn.fm/uZgfK). Between Snow Creek and the company’s second British Columbia gold property, the Rosella Creek mine, GEMXX reports estimated production potential of over 100,000 ounces of easily recoverable gold (https://ibn.fm/b9nQn). GEMXX is working to acquire a third gold property with an estimated 2.2 million to 4 million ounces of recoverable gold.

GEMXX’s control over each stage of its production — from mining to processing the product and further to manufacturing end-product jewelry then worldwide distribution — gives the company a distinct competitive advantage over other players in the precious metals sector.

Those interested in participating through Reg A financing are encouraged to visit the company’s investor page (https://ibn.fm/u1Sd0) or contact company officials for more information (ir@gemxx.com – 702-930-1815).

For more information, visit the company’s website at www.GEMXX.com/investors.

NOTE TO INVESTORS: The latest news and updates relating to GEMZ are available in the company’s newsroom at https://ibn.fm/GEMZ

• SOHM is launching a line of 13 new chewables that offer a range of health benefits and expand the company’s preventative care product portfolio
• The new line will be available online through Amazon.com and the company’s direct-to-consumer website and will be showcased at industry conferences in 2024
• SOHM is addressing its increased product demand by establishing a new CDMO GMP manufacturing facility in Carlsbad, California
• The new manufacturing facility is expected to be open by the end of 2023, and shareholders will be updated about its operations during its year-end 2023 report

SOHM (OTC: SHMN), a pharmaceutical, nutraceutical, and cosmeceutical company that manufactures and markets generic drugs covering numerous treatment categories, recently announced the launch of new products to the company’s catalog and expansion into a new CDMO GMP manufacturing facility in Carlsbad, California.

SOHM is set to enter the global vitamin gummies market by launching 13 new SOHM Nutrients Brand Chewables. The global vitamins market, valued at $6.84 billion in 2022, is expected to reach $18.76 billion by 2031, driven by increased consumer spending on healthcare and self-care products, health benefits, appealing flavors, convenience, and easy accessibility (https://ibn.fm/96fvb).

The suite of SOHM Nutrients’ Brand Chewables offers a range of health benefits, individually wrapped single servings for convenience, a chewable format that requires no water, and delicious flavors like mango, strawberry, pineapple, and toffee (https://ibn.fm/58luQ). These products are vegan-friendly and free from nuts, gluten, gelatin, and soy. Dr. David Aguilar, COO of SOHM, emphasized its commitment to expanding its preventive care product portfolio and announced plans for additional product launches in 2024.

The new chewables will be available for retail purchase on Amazon.com and the company’s Direct-to-Consumer website, priced competitively with top-selling gummies. SOHM also plans to showcase these products at industry conferences in 2024, with conference schedules pending finalization.

SOHM has unveiled plans to address increasing product demand by establishing a new facility in Carlsbad, California (https://ibn.fm/1VB5C). This strategic move is driven by the need to meet existing and anticipated orders while the company’s primary facility in downtown San Diego undergoes renovations to optimize operations. SOHM is on track to complete the engineering batches produced at the San Diego facility by Q1 2024, aligning with its mission to enhance production capacity and efficiency.

The new Carlsbad facility provides ample space to accommodate the manufacturing of topical products and SOHM’s overall operations, with an additional 2,500 square feet allocated for storing finished products. Initial operations at the Carlsbad facility will have a daily capacity of 500 gallons (1,892 liters) and focus on topical products. However, plans are in place to expand its capabilities to include soft-gel suppositories by the end of Q1 2024 or the beginning of Q2 2024.

The Carlsbad facility is nearing completion, expecting to achieve full cGMP manufacturing capacity by December 2023. This expansion comes at an opportune time as the bio and pharma Contract Development and Manufacturing Organization (“CDMO”) market has reached a value of $223 billion in 2023 and is projected to grow to $309 billion by 2028, reflecting a 6.74% Compound Annual Growth Rate (“CAGR”) between 2018 and 2028 (https://ibn.fm/352dR).

The company’s management anticipates sharing further updates on the Carlsbad facility in its year-end 2023 report and expresses gratitude for its stakeholders’ continued support and trust. This expansion signifies SOHM’s commitment to meeting market demands and facilitating growth in the pharmaceutical manufacturing sector.

For more information, visit the company’s website at www.SOHM.com.

NOTE TO INVESTORS: The latest news and updates relating to SHMN are available in the company’s newsroom at https://ibn.fm/SHMN

• SuperCom recently secured a new contract to deploy its cutting-edge solutions as part of its broader plan to enhance public safety and support rehabilitation efforts in communities across Kentucky
• The contract reaffirms the company’s commitment to innovation and excellence in the field of electronic monitoring, according to Ordan Trabelsi, SuperCom’s CEO and President
• It also marks another valuable step in the company’s expansion within the U.S.
• The contract allows the company to bring its advanced technology to more communities and aid in the crucial work of domestic violence prevention and offender monitoring

SuperCom (NASDAQ: SPCB), a leading global provider of advanced safety, identification, connectivity, and security products and solutions to governments as well as public and private organizations around the world, recently secured a new contract with a Kentucky-based prominent service provider of electronic monitoring (“EM”) products and services. Under this new contract, SuperCom will deploy its newest proprietary technologies, namely the new PureOne GPS bracelet and the PureProtect for domestic violence protection (https://ibn.fm/TZeXu).

“We are proud to see our new proprietary solutions gaining traction in new regions in the U.S., reaffirming our commitment to innovation and excellence in the field of electronic monitoring. This new contract allows us to bring our advanced technology to more communities and aid in the crucial work of domestic violence prevention and offender monitoring. It is a testament to the hard work of our team and the trust our partners place in our technology,” said SuperCom CEO and President Ordan Trabelsi.

The PureOne monitoring solution is an all-in-one device that contains Global Navigation Satellite Systems (“GNSS”), LTE cellular, and radio-frequency (“RF”) Bluetooth low energy (“BLE”) modules. The integrated BLE module enables the device to communicate with the PureBeacon, a secure RF device that provides surveillance of offenders when GPS is not suitable or available. On the other hand, the GNSS module relies on satellites to provide geo-positioning data, while the cellular module facilitates communication with PureMonitor. SuperCom’s PureMonitor is cloud-based software that remotely monitors the PureOne device and its user, sends alerts, creates reports, and performs analytics.

PureProtect is a smartphone application that supports GNSS, Wi-Fi location, and location-based service (“LBS”) tracking, as well as LTE and 5G cellular communication. It can send GNSS and RF proximity range alerts and displays an on-screen map that shows the aggressor’s and victim’s location. It also has an SOS emergency panic button that victims can use in case of immediate danger. Thanks to these features and capabilities, the PureProtect app links SuperCom’s disparate domestic violence solutions – the PureOne bracelet and the PureMonitor software – offering a protective front line for victims of domestic violence.

SuperCom’s move to deploy these cutting-edge solutions as part of the new contract aligns with its broader plan to enhance public safety and support rehabilitation efforts in communities across Kentucky. It also marks another valuable step in the company’s expansion within the U.S., given that SuperCom has previously signed EM contracts in Idaho, California, and Texas. The new contract builds on the company’s continued success in delivering high-quality services and cutting-edge monitoring solutions within and across state borders.

“Our commitment to improving public safety and supporting rehabilitation efforts is at the core of our mission. Leveraging our growing customer base and technology expertise, we plan to continue developing and providing advanced solutions that meet the evolving needs in our industry and help enhance public safety worldwide,” concluded Trabelsi.

For more information, visit the company’s website at www.SuperCom.com.

NOTE TO INVESTORS: The latest news and updates relating to SPCB are available in the company’s newsroom at http://ibn.fm/SPCB