• PowerBank Corporation has secured all required municipal approvals for two 14.4 MW solar projects in the community of Skaneateles in upstate New York.
• The projects will be built on industrial brownfield sites in Onondaga County, repurposing unused land, with the projects supporting New York’s Climate Leadership and Community Protection Act goal of 6 GW of solar capacity by 2025.
• The company is now awaiting approval from the New York Department of Environmental Conservation and intends to begin construction if approval and financing are received.
• Once operational, the projects will provide clean energy to the grid, with subscribers earning credits on their electricity bill every month.
• PowerBank has more than 100 MW of completed projects and a 1 GW pipeline across North America.

Disseminated on behalf of PowerBank Corporation

PowerBank (NASDAQ: SUUN) (Cboe CA: SUNN) (FSE: GY2), a developer and owner of renewable and clean energy projects, specializing in distributed and community solar initiatives throughout Canada and the U.S., is moving forward with two new community solar projects in Skaneateles, New York, totaling 14.4 megawatts of capacity (https://ibn.fm/yLdyR). The company announced that it has obtained all municipal approvals, including variances, site plan approval, and a special use permit. The projects are now pursuing approval from the New York Department of Environmental Conservation (“DEC”) before construction can begin.

The two solar projects will be built on industrial brownfield sites in Onondaga County, within the Finger Lakes region. This approach  provides an environmentally beneficial reuse of sites that have otherwise limited economic potential. By installing panels on these brownfields, PowerBank is also addressing one of the common challenges to scaling solar: land availability. Industrial land often comes with fewer community concerns than farmland or residential developments.

The projects will contribute to New York State’s Climate Leadership and Community Protection Act, which set a target of 6 GW of solar capacity by 2025. New York has emerged as the U.S. leader in community solar, accounting for nearly one-third of the country’s 6.2 GW of installed capacity. 

Once operational, the Skaneateles projects will function as community solar facilities. Under this model, clean energy generated by the solar arrays will flow into the local grid, and households or renters can subscribe to the project. Subscribers then receive credits on their monthly utility bills tied to the energy their portion of the project generates (https://ibn.fm/VHeKt).

This allows participants to lower their electricity costs without the expense of installing rooftop panels. Community solar has become an important driver of renewable adoption in New York, where many homes are not suitable for rooftop systems.

Additionally, the regulatory framework in New York has provided strong incentives for community solar development, creating an attractive environment for developers and investors. PowerBank views these projects as part of its broader role in helping the state achieve its climate and energy goals.

PowerBank has completed over 100 MW of renewable energy projects to date and maintains a pipeline of more than 1 GW across North America. Its portfolio spans solar and battery energy storage system (“BESS”) projects, with a diverse set of offtake arrangements including utilities, commercial and industrial customers, municipalities, and community solar subscribers.

By focusing on distributed energy and community solar, PowerBank is building recurring revenue streams in a market segment with high growth potential. The Skaneateles projects, at 14.4 MW, highlight the company’s ability to execute on multiple fronts, from regulatory approvals to construction readiness.

Construction on the projects is expected to begin once DEC approval and financing are finalized. For PowerBank, these two projects represent another step in its strategy of delivering distributed renewable energy while capturing financial value through ownership and operation.

For more information, visit the company’s website at https://PowerBankCorp.com.

This report contains forward looking information. Please refer to the press releases entitled “PowerBank Advances 14.4 MW Projects in Skaneateles, New York” and dated September 9, 2025, and “PowerBank (SUUN) Updates on Skaneateles Community Solar Projects” and dated September 11, 2025, for additional details on the information, risks and assumptions.

NOTE TO INVESTORS: The latest news and updates relating to SUUN are available in the company’s newsroom at https://ibn.fm/SUUN

• Canadian gold explorer and near-term producer LaFleur Minerals recently completed a fully subscribed non-brokered private placement funding for gross proceeds of C$2.88 million, with additional offerings expected to be completed soon
• The company’s capital raises are designed to help it restart its fully permitted Beacon Gold Mill as well as advance exploration and drilling efforts in the heart of the renowned Abitibi Greenstone Belt at its district-scale Swanson Gold Project
• LaFleur anticipates its fully owned Beacon Gold Mill will deliver near-term revenues from processing mineralized material from neighboring gold deposits and potentially producing material sourced from its Swanson Gold Deposit only 60 km away
• LaFleur has already completed over seven diamond drill holes on its Swanson Gold Project close to the Val-d’Or, Quebec gold district with assay results still pending

Gold exploration and development company LaFleur Minerals (CSE: LFLR) (OTCQB: LFLRF) recently announced the completion of a non-brokered private placement valued at C$2.88 million, showing that its efforts to generate confidence in its advanced stage exploration Swanson Gold Project in Quebec, Canada is beginning to deliver results, along with its near-term producing Beacon Gold Mill once restart financing is secured.

LaFleur Minerals is a Canada-headquartered company developing approximately 18,304 hectares (45,230 acres) of the Swanson site it believes will yield gold, thanks to initial investigation and the amount of gold recovery nearby, along with extensive data and results from over 36,000 metres of historical drilling. It is also anticipating a near-term revenue stream to support its exploration through the milling of other nearby gold miners’ mineralized material at its wholly-owned Beacon Gold Mill.

The non-brokered private placement of “LIFE offering” share units is one facet of its initiative to capitalize its potential gold projects in the heart of the Abitibi Greenstone Belt, a globally renowned gold district, where the company began a 5,000-metre drill program at Swanson this summer with assay results expected within the next few weeks.

The company also intends to close its previously announced offering of up to 3.75 million charity flow-through units for gross proceeds of up to $2.59 million, and a non-brokered hard dollar private placement for proceeds of up to $700,000, according to a Sept. 10 news release (https://ibn.fm/TToqM), as it also seeks to secure the mill restart financing of C$5-6 million, a debt financing initiative led by FMI Securities Inc. and FMI Capital Partners Group.

LaFleur is also pursuing various strategic marketing and investor relations engagements with arms-length independent contractors and agencies to build the company’s strategy for communicating with a wider audience. A key element of that message is the variety of findings and high-grade targets at the Swanson site that indicate potential gold mineralization near other already established gold exploration sites at Val-d’Or, Quebec.

Core logging of recent drill holes completed at Swanson shows the consistent presence of pyrite and other sulfides that are classic pathfinder minerals for gold, with a 17.9-meter-wide sulphide-rich zone and fuchsite alteration in one of the drill holes that also is a classic pathfinder frequently associated with gold mineralization in the Abitibi.

“We are very encouraged by the early progress of the Swanson drilling program and the geological and mineralization similarities seen in the recent drill core to the known Swanson Gold Deposit,” LaFleur CEO Paul Teniere stated Aug. 7 (https://ibn.fm/twvvR). “We look forward to releasing assay results in the near future.”

At the same time, LaFleur has the potential to benefit from the upside of restarting production operations and revenue generation from its fully permitted and recently refurbished Beacon Gold Mill, an asset valued over C$71 million replacement cost. As gold prices have skyrocketed in recent months, other miners have seen an incentive to get their ore processed as quickly as possible to take advantage of the market’s optimism, and LaFleur serves as a valuable conduit to surrounding, regional deposits that want to jump start into production without a processing facility.

The 100%-owned mill is capable of processing over 750 metric tons per day once an estimated C$5 million in restart upgrades take place, highlighting the low restart cost and immense upside potential at hand for this easily accessible and strategically positioned asset. The Beacon Gold Mill  had received more than C$20 million in equipment and other upgrades by the former owner before LaFleur purchased it in bankruptcy proceedings for a small fraction of its value.

For more information, visit the company’s website at LaFleurMinerals.com.

NOTE TO INVESTORS: The latest news and updates relating to LFLRF are available in the company’s newsroom at https://ibn.fm/LFLRF

Qualified Person Statement:

All scientific and technical information contained in this article has been reviewed and approved by Louis Martin, P.Geo. (OGQ), Exploration Manager and Technical Advisor of the company and considered a Qualified Person for the purposes of NI 43-101.

• Beeline Holdings has paid down all of its outstanding debt, excluding warehouse lines tied to mortgage originations, and expects to achieve cash flow positive operations by Q1 2026.
• Q2 2025 revenue rose 27% quarter-over-quarter to $1.7 million, with costs cut 40%.
• New product launches include BeelineEQUITY, BlinkQC, and an AI mortgage chatbot.
• Management has been buying shares, signaling confidence in the company’s trajectory, and will present its growth strategy at the Centurion One Capital Summit in October 2025.

Beeline Holdings (NASDAQ: BLNE),  a digital mortgage platform redefining the path to homeownership, has eliminated over $7 million in debt and is positioning itself to become cash flow positive by the first quarter of 2026. The company said all notes payable and secured credit facilities, including senior secured debentures, have been repaid as of September 3, 2025. Warehouse lines used to fund mortgage transactions remain active, but these are short-term instruments that recycle when loans are sold (https://ibn.fm/LTFzp).

Chief Executive Nick Liuzza called the milestone a major step in strengthening the company’s financial foundation. “Becoming debt-free by the end of 2025 was one of our key strategic goals. Achieving this milestone earlier than planned strengthens our financial foundation and allows us to focus fully on growth and innovation. It’s a testament to our team’s discipline and execution,” he said.

Beeline is also stepping up efforts to connect with the investment community. The company will present at the Centurion One Capital Summit in the Bahamas on October 28–29, 2025. Liuzza, Chief Financial Officer Chris Moe, and Chief Operating Officer Jessica Kennedy, will outline the company’s growth strategy and timeline toward profitability (https://ibn.fm/1Lp7p).

Management has backed up its statements with insider buying. Kennedy acquired 100,000 shares last week, while Moe bought 20,000 and Chief Accounting Officer Tiffany Milton purchased 10,000. Liuzza added 3,000 shares, bringing his personal stake to more than $16 million.

These developments come as the company has been narrowing losses and growing revenue through its AI-powered mortgage platform. In Q2 2025, the company posted $1.7 million in revenue, up 27% from the previous quarter, while operating costs fell 40% to $5.6 million. Net loss for the quarter stood at $4.1 million, a 68% improvement over Q1. Adjusted EBITDA also improved, moving from -$3.5 million to -$2.8 million.

The company funded $52 million in mortgage loans during the quarter, a 31% increase from Q1. Streetwise Reports highlighted the results, noting that Beeline’s trajectory suggests it is on track to hit profitability in January 2026 and that analysts believe the company is a “Buy” (https://ibn.fm/CnWj0). According to the report, Beeline’s July revenue was 15% higher than April 2025, Beeline’s best-performing month in three years. The company also cut marketing expenses by 20% compared with Q1, contributing to cost efficiency.

Beeline’s technology differentiates it in a mortgage market still adjusting to higher interest rates and tighter credit conditions. The company’s AI-driven platform aims to streamline origination, reduce costs, and improve customer acquisition. By combining mortgage and title services in one digital process, Beeline is seeking efficiency gains that traditional lenders struggle to achieve.

The company has been rolling out products that extend its reach beyond conventional digital mortgage services. Among these is BeelineEQUITY, an equity sale program that allows homeowners to sell up to 49% of their home equity to investors rather than taking on new debt. The company completed its first transaction under the program in June and expects to close ten more before a full-scale launch in late October.

Other launches include BlinkQC, an AI-powered quality control tool that automates preclosing audits for lenders, and “Bob,” an AI chatbot designed to assist mortgage applicants. During beta testing, Bob converted chats into leads at six times the rate of human agents, generating $162,500 in revenue with minimal cost.

For more information, visit the company’s website at www.MakeABeeline.com.

NOTE TO INVESTORS: The latest news and updates relating to BLNE are available in the company’s newsroom at https://ibn.fm/BLNE

• SuperCom CEO Ordan Trabelsi attended the Q3 Investor Summit Virtual on September 16, 2025, highlighting the company’s expansion in the U.S. corrections market with over 30 contracts across 11 new states since mid-2024.
• The company’s PureSecurity(TM) platform has demonstrated recurring-revenue potential through GPS, RFID, and cloud-based electronic monitoring solutions.
• Financial results showed significant profitability gains, with net income up nearly 80% in the first half of 2025.
• The company continued to diversify internationally with projects in Israel, Europe and the U.S.
• With growing balance sheet strength and scalable technologies, SuperCom has improved its positioning for future opportunities.

SuperCom (NASDAQ: SPCB), a global provider of secured e-Government, IoT, and cybersecurity solutions, participated in the Q3 Investor Summit Virtual on September 16, 2025. President and CEO Ordan Trabelsi outlined the company’s recent milestones and strategic direction to an audience of small- and microcap investors (https://ibn.fm/3xi08).

The Investor Summit is an exclusive virtual event for investors specializing in small and microcap stocks. This quarter’s edition focused on microcap companies that have strong growth catalysts, offering attendees a unique platform for discovery and engagement with potential investments. During the event investors were able to learn from industry experts and thought leaders, explore multiple investment opportunities in the microcap segment, and hear directly from company executives about their firms’ key milestones and strategies.

SuperCom’s presentation highlighted the company’s rapid progress in electronic monitoring (“EM”), an area that has become central to its growth strategy. EM is increasingly being adopted by governments as a cost-efficient alternative to incarceration, with studies suggesting it can reduce recidivism by around 40%.

Another key achievement discussed during the event was SuperCom’s significant expansion in the U.S. over the past year. Since mid-2024, the company signed more than 30 contracts, entering 11 new states. Notable wins included a Tennessee program transition, a Virginia project that replaced an incumbent provider, and a statewide procurement deal with the North Carolina Sheriff’s Association. In August 2025, the company announced a second contract in Alabama, awarded following a customer referral. Management emphasized that referrals had become an important driver of adoption in regions where the company already operated.

The growth was anchored by SuperCom’s modular PureSecurity(TM) platform. The system integrates GPS, RFID, and cloud-based monitoring, offering tools such as PureOne(TM) tracking bracelets, PureShield(TM) domestic violence enforcement, PureProtect(TM) victim-alert apps, and PureMonitor(TM) software for law enforcement agencies.

While U.S. expansion dominated recent developments, SuperCom also retained a global outlook. In Israel, the company, together with Electra Security, won a national EM contract with the Israel Prison Service, deploying more than 1,500 PureSecurity units. In Europe, SuperCom secured more than 15 nationwide projects, highlighting the adaptability of its solutions across jurisdictions. These international projects diversified revenue streams and reduced dependence on any single market.

The company’s financial results were also addressed. In the first half of 2025, revenue came in at $14.2 million, roughly flat year-on-year, but profitability showed sharp improvement: gross profit rose 15% to $8.7 million and net income climbed 79.5% to $5.3 million. Cash and equivalents more than doubled to $15 million, while working capital rose to $40.8 million. 

Trabelsi’s presentation, available for viewing on the event’s website at https://ibn.fm/7J4Uf, made clear that SuperCom intends to build further on its EM business. With its technology already tested across multiple continents and financial metrics trending positively, the company is well placed to capitalize on both domestic and international opportunities.

For more information, visit the company’s website at www.SuperCom.com.

NOTE TO INVESTORS: The latest news and updates relating to SPCB are available in the company’s newsroom at https://ibn.fm/SPCB

• On the global stage, the Cancer Atlas estimates a dramatic rise in cancer cases, adding urgency to the need for therapeutic innovation
• Oncotelic’s mission focuses on developing first-in-class RNA therapeutics and small-molecule drugs to serve high-unmet-need cancers and rare pediatric diseases
• This year, the company achieved a major milestone by successfully completing a phase 1 clinical trial evaluating OT-101 combining Interleukin-2

In a landscape where cancer and underserved diseases continue to devastate millions, the demand for groundbreaking RNA-based, immunotherapeutic, and targeted treatments has never been more urgent. Oncotelic Therapeutics (OTCQB: OTLC) is answering this call with pioneering RNA candidates and strategic programs aimed at some of the most lethal and overlooked cancers.

The global cancer burden is both vast and growing. In the United States alone, an estimated 2,041,910 new cancer cases and 618,120 cancer-related deaths are projected for 2025, including conditions such as lung, breast, prostate and colorectal cancers that dominate incidence and mortality statistics (ibn.fm/M7MFi). On the global stage, the Cancer Atlas estimates a dramatic rise in cancer cases, from 20 million new cases in 2022 to an anticipated 35 million by 2050, adding urgency to the need for therapeutic innovation (ibn.fm/D6Vs8). The scale of these figures underlines the importance of developing more effective, accessible treatments for both common and rare forms of cancer.

Immunotherapy and RNA-based approaches have begun to reshape the understanding of cancer treatment. The FDA approved 17 new immunotherapies in 2024 alone, spanning multiple cancer types and delivering breakthroughs such as checkpoint inhibitors and individualized vaccines (ibn.fm/KuJTN). Yet despite this progress, significant unmet needs persist, particularly in rare pediatric cancers, resistant solid tumors and underserved population. Oncotelic is strategically positioned to fill gaps where traditional treatments fall short.

Oncotelic’s mission focuses on developing first-in-class RNA therapeutics and small-molecule drugs to serve high-unmet-need cancers and rare pediatric diseases (ibn.fm/rBiPA). Its lead candidate, OT-101, is a pioneering anti-TGF-β RNA therapeutic that has demonstrated single-agent activity in relapsed and refractory cancers (ibn.fm/gW9iN). OT-101 also exhibits activity against SARS-CoV-2, underscoring its versatile potential. Importantly, OT-101 has received rare pediatric designations for aggressive diseases such as diffuse intrinsic pontine glioma (“DIPG”), melanoma (via CA4P) and acute myeloid leukemia (via OXi4503), highlighting the company’s focus on underserved populations. 

This year, Oncotelic achieved a major milestone by successfully completing a phase 1 clinical trial evaluating OT-101 in combination with Interleukin-2 in patients with advanced or metastatic solid tumors (ibn.fm/fj4eM). The trial demonstrated a favorable safety and tolerability profile, clearing the way for next-stage efficacy trials, which may include combinations with checkpoint inhibitors for cancers like lung, melanoma, and colorectal disease.

Beyond its clinical assets, Oncotelic’s strategic breadth is bolstered by a robust intellectual property foundation and expansion via joint ventures. The company currently holds 45% ownership of GMP Bio, a joint venture that advances nanomedicine pipeline under the leadership of CEO Dr. Vuong Trieu (ibn.fm/65vo6). Trieu’s leadership extends to a portfolio that includes more than 500 patent applications and 75 issued U.S. patents centered on tumor microenvironment biology and drug delivery innovations (ibn.fm/9DoDS).

Oncotelic isn’t just developing drugs; the company is constructing a biotech ecosystem capable of delivering personalized, effective treatments for diseases that remain largely untreated. Its pipeline spans from RNA-based immuno-oncology to small-molecule repositioning and extends into rare pediatric indications, positioning the company as a diversified innovator. The success of OT-101’s clinical trajectory, combined with GMP Bio’s emerging nanomedicine pipeline and Trieu’s IP legacy, forms a compelling platform for future growth and therapeutic breakthroughs.

For more information, visit the company’s website at www.Oncotelic.com.

NOTE TO INVESTORS: The latest news and updates relating to OTLC are available in the company’s newsroom at ibn.fm/OTLC

• D-Wave is hosting a quantum computing user conference called Qubits Japan 2025 in Tokyo on September 17, 2025.
• The event is themed “Quantum Realized” and will feature presentations highlighting customer success stories, technical roadmap updates, scientific achievements and advancements in quantum AI.
• This follows an 83% increase in bookings for D-Wave’s annealing quantum computing technology in the Asia Pacific region as organizations develop optimization and quantum AI applications

D-Wave Quantum Inc. (NYSE: QBTS) (“D-Wave” or “The Company”), a leader in quantum computing systems, software, and services, recently announced that it is hosting its first-ever Qubits Japan 2025 quantum computing user conference in Tokyo on September 17 to support growing interest and adoption of annealing quantum computing technology across the Asia Pacific (“APAC”) region. 

The conference, which is themed “Quantum Realized,” will feature presentations from D-Wave executives, customers, and thought leaders that showcase how D-Wave’s quantum technology is already delivering tangible value today. Notable speakers who will present at the event include Dr. Alan Baratz, CEO of D-Wave, Dr. Trevor Lanting, CDO of D-Wave, Dr. Masaru Tateno, CSO of Japan Tobacco’s Pharmaceutical Research Center, and Hidetoshi Nishimori, professor emeritus at the Institute of Science Tokyo.

The announcement comes at a time when D-Wave is experiencing growth across the APAC region, with bookings up 83% over the past 12 months. APAC customers are increasingly exploring, adopting, and using D-Wave’s annealing quantum computing technology to solve complex challenges spanning artificial intelligence (“AI”)/machine learning and business optimization problems.

The pharmaceutical division of Japan Tobacco Inc. has signed a new agreement with D-Wave to facilitate a pilot project related to the companies’ joint work in quantum AI drug discovery. The pilot marks the next step toward production deployment based on the success of a completed joint proof-of-concept earlier this year.

NTT DOCOMO Inc. (NTT DOCOMO), Japan’s largest mobile phone operator with over 90 million subscribers, announced a quantum optimization pilot in 2024 that resulted in demonstrable mobile network performance improvements. Using D-Wave’s annealing quantum computing solutions, NTT DOCOMO found that it can reduce congestion at base stations by decreasing paging signals during peak calling times by 15%, potentially leading to increased efficiencies and lower infrastructure costs. NTT DOCOMO’s network signal optimization is now available throughout Japan, and the company is exploring new quantum use cases.

In June 2025, D-Wave announced a strategic relationship with Yonsei University and Incheon Metropolitan City to accelerate the exploration, adoption and usage of quantum computing in South Korea. Under terms of the Memorandum of Understanding (“MOU”), the three organizations intend to work together to advance mutual research and talent development for quantum computing, provide access to D-Wave’s quantum computing technology, and collaborate on development of use cases in biotechnology, materials science and other areas. In addition, the MOU facilitates the organizations’ efforts towards the acquisition of a D-Wave Advantage2(TM) system at the Yonsei University International Campus in Songdo, Yeonsu-gu, Incheon.

“Asia—and especially Japan—is becoming an important epicenter of quantum computing innovation, development and adoption,” said Dr. Alan Baratz, CEO of D-Wave. “Japan is the birthplace of the original concept of quantum annealing, first proposed by Hidetoshi Nishimori and Tadashi Kadowaki. Fast forward nearly 30 years, and we’re seeing first-hand how this powerful technology can address some of business’s and science’s most computationally complex problems. We’re thrilled to bring together the quantum ecosystem for Qubits Japan 2025 to continue fostering this important dialogue in the region.”

To register for the event, visit: https://www.eventzilla.net/e/qubits-japan-25-2138656678 

About D-Wave Quantum Inc.

D-Wave is a leader in the development and delivery of quantum computing systems, software, and services. We are the world’s first commercial supplier of quantum computers, and the only company building both annealing and gate-model quantum computers. Our mission is to help customers realize the value of quantum, today. Our quantum computers — the world’s largest — feature QPUs with sub-second response times and can be deployed on-premises or accessed through our quantum cloud service, which offers 99.9% availability and uptime. More than 100 organizations trust D-Wave with their toughest computational challenges. With over 200 million problems submitted to our quantum systems to date, our customers apply our technology to address use cases spanning optimization, artificial intelligence, research and more. Learn more about realizing the value of quantum computing today and how we’re shaping the quantum-driven industrial and societal advancements of tomorrow: www.dwavequantum.com.

NOTE TO INVESTORS: The latest news and updates relating to QBTS are available in the company’s newsroom at https://ibn.fm/QBTS

Forward Looking Statements

Certain statements in this press release are forward-looking, as defined in the Private Securities Litigation Reform Act of 1995. These statements involve risks, uncertainties, and other factors that may cause actual results to differ materially from the information expressed or implied by these forward-looking statements and may not be indicative of future results. These forward-looking statements are subject to a number of risks and uncertainties, including, among others, various factors beyond management’s control, including the risks set forth under the heading “Risk Factors” discussed under the caption “Item 1A. Risk Factors” in Part I of our most recent Annual Report on Form 10-K or any updates discussed under the caption “Item 1A. Risk Factors” in Part II of our Quarterly Reports on Form 10-Q and in our other filings with the SEC. Undue reliance should not be placed on the forward-looking statements in this press release in making an investment decision, which are based on information available to us on the date hereof. We undertake no duty to update this information unless required by law.

• Clene Inc. reported new preclinical data on its drug candidate CNM-Au8 for Parkinson’s disease.
• The therapy improved mitochondrial health, restored cellular metabolism, reduced inflammation, and normalized gene expression in dopaminergic neurons.
• Findings were presented at the Michael J. Fox Foundation’s H2 Therapeutics Stewardship Meeting in New York City.
• CNM-Au8 previously showed positive energetic and metabolic effects in a Phase 2 Parkinson’s trial, aligning with the new preclinical results.
• The treatment demonstrated no toxicity in neuronal models, consistent with safety data from over 1,000 patient-years in ALS and MS trials.
• Clene plans to design a Phase 2 clinical study for Parkinson’s disease while advancing ALS and MS programs.

Clene (NASDAQ: CLNN) and its wholly owned subsidiary, Clene Nanomedicine Inc., a late clinical-stage biopharmaceutical company focused on improving mitochondrial health and protecting neuronal function to treat neurodegenerative diseases, has presented encouraging preclinical findings for its lead investigational therapy, CNM-Au8, in Parkinson’s disease. The data, announced earlier in September 2025, highlight the drug’s potential to address key cellular and energetic deficits that drive disease progression (https://ibn.fm/EECHU).

The results were unveiled at the Michael J. Fox Foundation’s H2 Therapeutics Stewardship Meeting in New York City. Researchers reported that CNM-Au8 improved mitochondrial health, reduced harmful inflammation, restored energy metabolism, and normalized disrupted gene expression in dopaminergic neurons derived from Parkinson’s patients.

The study was carried out by Associate Professor Jerome Mertens in collaboration with Dr. Fred Gage of the Salk Institute, and Clene’s Vice President of Translational Medicine, Karen S. Ho, Ph.D. Using skin cells collected from Parkinson’s patients, scientists directly converted them into dopaminergic neurons, the same type of brain cells most vulnerable in the disease.

Importantly, the model retained age-related features from patients, offering a more accurate representation of disease processes compared with traditional laboratory systems. The cohort included neurons from 14 familial Parkinson’s disease (“fPD”) patients, 8 sporadic PD (“sPD”) patients, and 13 healthy controls.

Across both familial and sporadic Parkinson’s disease neurons, CNM-Au8 delivered several notable improvements:

• Mitochondrial health: In fPD neurons, CNM-Au8 improved mitochondrial membrane potential, increased mitochondrial volume, and reduced damaging reactive oxygen species. Milder but similar effects were seen in sporadic PD neurons.
• Inflammation reduction: The therapy lowered inflammatory proteins such as CD40 and CXCL10, helping reduce neuroinflammation, a driver of disease progression.
• Restored metabolism: CNM-Au8 improved the NAD+/NADH ratio, a key measure of cellular energy, and corrected significant portions of dysregulated metabolites, particularly in energy and nucleotide pathways.
• Gene expression normalization: Treatment reversed many of the gene expression abnormalities associated with Parkinson’s disease, bringing patterns closer to healthy control neurons.
• Safety: The compound did not show toxicity toward dopaminergic neurons at any dose. This finding is consistent with safety data from ongoing amyotrophic lateral sclerosis (“ALS”) and multiple sclerosis (“MS”) trials, where CNM-Au8 has accumulated more than 1,000 patient-years of exposure without major concerns.

“Parkinson’s disease has complex and multifactorial causes, but mitochondrial dysfunction, chronic inflammation, and disrupted metabolism are consistent hallmarks,” said Dr. Mertens of the Salk Institute. “These results, generated in an advanced model that reflects both the genetics and the aging process of PD, add to the growing body of evidence that CNM-Au8’s catalytic metabolic effects on mitochondrial health, energy metabolism, neuroinflammation, and gene expression could have broad therapeutic potential for the treatment of Parkinson’s disease and other neurodegenerative disorders.”

Clene’s pipeline focuses on neurodegenerative conditions driven by mitochondrial dysfunction and energetic failure. CNM-Au8, an oral suspension of gold nanocrystals, is designed to restore energy metabolism and neuronal resilience. The therapy has already advanced into late-stage testing in other diseases. A Phase 2 Parkinson’s trial previously showed that oral CNM-Au8 altered key brain energy metabolites (NAD+, NADH, ATP) in patients, supporting the preclinical findings now presented.

Benjamin Greenberg, M.D., Clene’s Head of Medical, noted that the company is preparing a Phase 2 clinical study of CNM-Au8 in Parkinson’s, while continuing late-stage ALS trials and discussions with the FDA regarding a Phase 3 program in multiple sclerosis.

“CNM-Au8 has a unique nanocatalytic mechanism of action that favors its application to many neurodegenerative diseases that have mitochondrial dysfunction and energetic failure at their core,” said Greenberg. “We are grateful to the MJFF for supporting this work, and to the Salk Institute for such a meaningful collaboration. These promising preclinical results strengthen the body of evidence supporting further clinical development of CNM-Au8 for the treatment of Parkinson’s disease.”

For more information, visit the company’s website at www.Clene.com.

NOTE TO INVESTORS: The latest news and updates relating to CLNN are available in the company’s newsroom at https://ibn.fm/CLNN

• Micropolis is a first-mover in AI-powered autonomous mobility within the GCC, backed by longstanding relationships with major public-sector stakeholders like Dubai Police.
• Its vertically integrated platform architecture supports rapid product customization across a wide range of industries and operational use cases.
• The company is actively expanding its footprint beyond the UAE through exclusive distribution agreements in Egypt and North Africa.
• Multiple product lines, including robotics for security, sanitation, logistics, and environmental restoration, offer diversified growth pathways.
• Recent IPO proceeds are being deployed into R&D, talent acquisition, and commercialization, accelerating the company’s path toward scaled global deployment.

Micropolis (NYSE American: MCRP) is a robotics and AI technology company pioneering the development of unmanned ground vehicles (“UGVs”), autonomous mobility platforms, and smart infrastructure for security, industrial, and urban applications. Since its founding in 2014, the company has evolved from a software startup into a fully integrated robotics manufacturer with expertise spanning mechatronics, embedded systems, AI software, and high-level autonomy. Its core technology is centered on modularity and adaptability, enabling Micropolis to deploy scalable robotics solutions across a wide range of industries and environments.

The company’s mission is rooted in a vision of harmonious human-machine collaboration, where intelligent automation drives sustainable progress. Through a growing portfolio of partnerships with public and private sector clients, including defense agencies, municipalities, and industrial operators, Micropolis aims to transform how the world approaches mobility, surveillance, and operational efficiency. These solutions are engineered not just to automate tasks, but to meaningfully enhance safety, sustainability, and strategic readiness in high-impact environments.

Following its initial public offering on the NYSE American in March 2025, Micropolis has accelerated the rollout of its autonomous platforms through regional pilots, strategic agreements, and ongoing R&D efforts.

The company is headquartered in Dubai, UAE.

Products

Micropolis offers a robust portfolio of autonomous robotics platforms, control systems, and AI software designed to meet the complex needs of security, industrial, and smart city applications.

M-Platform

Micropolis’ core robotics architecture is built around the M-Platform, a modular autonomous system composed of two primary components: a Mobility-Specific Platform (“MSP”) and an Application-Specific Pod (“ASP”). The MSP includes drive-by-wire and steer-by-wire systems, a custom suspension framework, and integrated power storage, all designed for durability and maneuverability in both urban and off-road environments. These platforms are compatible with a wide range of ASPs, enabling the same robotic base to be rapidly reconfigured for use cases in law enforcement, logistics, environmental cleanup, or public safety.

Advanced features across the platform include autonomous driving software, centralized control units, and AI-enhanced power management. Supporting technologies such as the Micropolis Robotic Control Unit (“MRCU”) and Smart Power Distribution Unit (“SPDU”) ensure high reliability, energy efficiency, and seamless integration with third-party systems. A compact mechanical design, high-precision control, and in-house R&D allow for scalable customization to match industry-specific requirements.

M-Patrol

The M-Patrol series includes specialized autonomous security and policing robots developed in collaboration with Dubai Police and other governmental entities. The M01 Patrol Unit is designed for open-road deployment, with speeds of 40–47 km/h and features like 360-degree AI vision, license plate recognition, crowd monitoring, and autonomous navigation. It is suited for high-traffic environments where rapid mobility and broad coverage are required.

The M02 Patrol Unit is built for enclosed or pedestrian-rich settings such as gated communities, offering a top speed of 7–10 km/h. It delivers low-speed, high-precision surveillance while maintaining safety in public-facing operations. In August 2025, Micropolis launched the final testing phase of the M02 platform in partnership with Dubai Expo City, Transguard Group, and Dubai Police. This pilot focused on validating advanced features including facial recognition, suspect tracking, behavior analysis, and autonomous navigation. Like the M01, the M02 is compatible with Micropolis’ proprietary command systems and can operate autonomously or under remote supervision.

Microspot

Microspot is Micropolis’ proprietary AI surveillance and analytics engine integrated into its robotic platforms. Initially co-developed with Dubai Police, Microspot enables real-time behavior analysis, facial recognition, and license plate detection through edge computing and machine learning algorithms. It is optimized for public safety use cases where rapid threat identification and decentralized processing are critical.

Micropolis’ recent agreement with AERXIO grants exclusive distribution rights of the company’s “Patrol” system, powered by Microspot, across Egypt and North Africa. This variant is engineered for border and desert operations, featuring a top speed of 50 km/h, a 15-hour runtime, and rapid charging capabilities. The integration of Microspot technology into these units allows for scalable deployment in both civilian and defense-oriented surveillance infrastructure.

Market Opportunity

Micropolis is strategically positioned to serve the growing demand for autonomous robotics and AI-powered systems across the Gulf Cooperation Council (“GCC”) and beyond. The company’s solutions address operational needs in urban security, logistics, defense, infrastructure, and environmental management—sectors that are undergoing rapid digital transformation in the Middle East.

Government initiatives in the UAE and Saudi Arabia have propelled the robotics and AI markets forward through funding, regulation, and institutional support. The UAE’s Strategy for Artificial Intelligence and Saudi Arabia’s Vision 2030 have created long-term national frameworks for automation and smart infrastructure adoption. Micropolis’ collaboration with public-sector partners, such as Dubai Police and SEE Holding’s Sustainable City 2.0, is aligned with these policy objectives and reflects growing national demand for autonomous technology.

Leadership Team

Fareed Aljawhari, Founder, Chief Executive Officer & Director, is a seasoned product designer and digital developer with over two decades of experience in Dubai’s digital transformation landscape. He founded Micropolis in 2014 and has led its evolution into a robotics and AI enterprise. He has cultivated strong relationships with government and private entities across the UAE, helping to position the company at the forefront of the region’s technology ecosystem.

Dzmitry Kastahorau, Chief Financial Officer, is a finance executive with international experience across the luxury retail, fashion, and automotive sectors. He holds a master’s degree in international corporate finance from EADA Business School in Barcelona and has previously held senior finance roles at Chalhoub Group, PUIG Spain, and Motherson Automotive in Germany.

For more information, visit the company’s website at www.Micropolis.ai.

NOTE TO INVESTORS: The latest news and updates relating to MCRP are available in the company’s newsroom at https://ibn.fm/MCRP

• Historic Alaska visit by the U.S. House Committee on Natural Resources underscores bipartisan recognition of the state’s strategic mineral potential amid China’s export restrictions
• Alaska Senator Murkowski’s push for domestic critical mineral production aligns with Trilogy’s Upper Kobuk Mineral Projects containing copper, zinc, cobalt, and other national security materials
• Pentagon interest in Alaska antimony projects highlights how geopolitical tensions are reshaping federal support for mineral development

The intersection of national security and mineral supply chains has reached a turning point. China’s export restrictions to the U.S. on critical minerals like gallium, germanium, antimony, and graphite, combined with its dominance in mineral processing, has transformed resource development in the U.S. from an economic issue into a strategic necessity. When congressional delegations make historic visits to mining regions, it signals that securing domestic mineral supplies is now central to maintaining America’s technological and military edge.

This policy evolution creates opportunities for companies positioned in stable jurisdictions with significant resources. Alaska, once viewed mainly through the lens of oil and gas, is now emerging as a strategic hub for minerals critical to U.S. security. Congressional attention, Pentagon interest, and global tensions together suggest that federal support for domestic mining is entering a new phase of urgency.

Historic Congressional Engagement

The recent visit by ten members of the House Committee on Natural Resources to Alaska was unprecedented. Led by Chairman Bruce Westerman, the delegation included both Republicans and Democrats, who toured active mines and met with state officials on resource policy.

The timing is critical. Committee members visited the Hecla Greens Creek Mine, which produces silver, gold, zinc, and lead, materials overlapping with Alaska’s broader mineral potential. Representative Pete Stauber emphasized that “Alaska can drive and lead the nation into both oil and gas and mineral exploration, if we’d allow them to do that,” reflecting recognition of regulatory hurdles.

Chairman Westerman highlighted America’s dependence on China for mineral processing, stressing that Congress must work to expand U.S. mining and refining capacity. This bipartisan engagement suggests that critical mineral security is beginning to transcend partisan divides when framed as a national security issue.

Pentagon Validates Strategic Risk

Parallel to congressional visits, Pentagon officials are weighing grants for Alaska antimony projects. The move underscores recognition that defense-critical supply chains cannot remain hostage to foreign powers.

China’s export ban in late 2024 weaponized America’s reliance on roughly 50 million pounds of imported antimony annually. With no domestic production available, the vulnerability became stark. The Pentagon’s interest signals that securing antimony, and by extension, other critical minerals like copper, zinc, and cobalt, is now a strategic defense priority.

Trilogy Metals’ Strategic Role

Trilogy Metals (NYSE American: TMQ) (TSX: TMQ) is well positioned in this shifting policy environment through its 50% ownership of the Upper Kobuk Mineral Projects (“UKMP”) in Alaska’s Ambler Mining District.

The Arctic deposit contains probable reserves of 46.7 million tonnes grading 2.11% copper, 2.9% zinc, and 0.56% lead, supported by a 2023 feasibility study valuing the project at $1.5 billion pre-tax NPV. Nearby, the Bornite project adds 6.5 billion pounds of copper and contains cobalt mineralization—key metals for defense applications, EV batteries, and grid-scale storage.

With Alaska’s governor and congressional delegation vocal in their support for responsible development, Trilogy operates in alignment with both state and national interests.

Infrastructure Becomes National Security

The proposed 211-mile Ambler Access Road, linking Trilogy’s projects to Alaska’s highway system, has gained new significance. Once viewed primarily as an economic development initiative, it is increasingly recognized as strategic infrastructure critical to domestic mineral security.

Recent executive orders and state initiatives underscore the growing willingness to support such projects. Historically, the federal government’s backing for strategic infrastructure has accelerated timelines during moments of national priority, a precedent that could apply here.

Trilogy’s partnership with South32, which invested $145 million to form their Ambler Metals LLC joint venture, provides the technical depth and financial strength to advance development as policy momentum builds.

Market Dynamics Reinforce Policy

Copper demand continues to surge from electrification, renewable energy, and data center expansion, even as supply growth lags due to declining ore grades and long permitting cycles. This supply-demand imbalance reinforces the strategic case for U.S. production.

Trilogy’s high-grade Arctic and Bornite deposits sit squarely at the intersection of market need and national policy. Their robust project economics, coupled with critical mineral content, create dual pathways for value creation: traditional market dynamics and potential federal support.

Strategic Inflection Point

Congressional attention, Pentagon engagement, and global supply chain pressures together highlight a fundamental shift in America’s approach to critical minerals. Trilogy Metals, with its large-scale copper, zinc, and cobalt resources in Alaska, operates at the center of this policy evolution.

As legislative action and defense initiatives translate into tangible support for domestic mining, projects like the Upper Kobuk Mineral Projects could evolve from promising resource developments into strategic national assets essential for technological and military competitiveness.

For more information, visit www.TrilogyMetals.com.

NOTE TO INVESTORS: The latest news and updates relating to TMQ are available in the company’s newsroom at ibn.fm/TMQ

• Juve Stabia’s Romeo Menti Stadium will host the inaugural Serie A Women’s Cup “Final Four” at the end of September 2025.
• Matches will be broadcast on Sky Sport and RAI, bringing national attention to Castellammare di Stabia.
• The event underscores Brera’s multi-club ownership strategy and investment in both men’s and women’s sports.
• Brera Holdings’ majority-owned Juve Stabia has seen its market value rise 245% over the past season.

Brera Holdings (NASDAQ: BREA), an Ireland-based international holding company focused on expanding its global portfolio of men’s and women’s sports clubs through a multi-club ownership (“MCO”) strategy, will host a milestone event in women’s football on its Italian club Juve Stabia’s stadium. The Romeo Menti Stadium in Castellammare di Stabia has been selected to stage the first-ever Serie A Women’s Cup “Final Four,” set for September 23-27, according to a company news release (https://ibn.fm/IDJbK).

The competition will feature four clubs: the three group winners and the best second-placed team from the 12-club Serie A Women’s league. The semifinals are scheduled for September 23 and 24, followed by the final on September 27. Matches will be broadcast live on Sky Sport, with the final airing nationally on RAI 2 and streaming on RaiPlay.

Ahead of the tournament, a press conference is planned for September 16 at the Reggia di Quisisana, a royal palace in Castellammare di Stabia. Attendees will include Mayor Luigi Vicinanza, Juve Stabia CEO Filippo Polcino, and Federica Cappelletti, President of Serie A Women.

Brera Holdings Executive Chairman Dan McClory described the event as an important opportunity for both the city and Italian women’s football. “It’s a great honor to host the Final Four at Juve Stabia’s Romeo Menti Stadium, and cast a spotlight on the highest level of Italian women’s professional soccer, Serie A, with such a prestigious event,” said McClory. “Bringing the 2025 Serie A Cup to Campania marks the return to southern Italy of the final stage of a major women’s event, two years after Juventus defeated Roma in the 2023 Coppa Italia Women’s Final in Salerno.”

For Brera Holdings, the event is not only about visibility but also about enhancing the profile of Juve Stabia, which the company acquired majority control of earlier this year. Brera’s 52% ownership of the club was finalized on June 20, 2025, following an agreement first announced in December 2024.

The acquisition is part of Brera’s broader multi-club ownership strategy, which aims to build a portfolio of football assets worldwide. Being the first MCO group listed on Nasdaq gives Brera a differentiated position in the market, offering public investors direct access to this ownership model.

Juve Stabia, also known as “The Other Team of Naples,” has been one of Serie B’s standout stories over the past season. After promotion from Serie C, the club not only held its own in Serie B but advanced into the promotion playoffs, reaching the semifinals. This strong performance has translated into a sharp increase in the club’s valuation. According to Transfermarkt and Social Media Soccer, Juve Stabia’s squad value rose by 245% during the 2024–25 season, from US$9.3 million to US$32 million.

Brera’s focus goes beyond financial returns. The company emphasizes innovation, socially impactful outcomes, and value creation across its portfolio. By investing in both men’s and women’s sports clubs, Brera is targeting a growing market where the commercial potential of women’s sports is increasingly recognized by sponsors, broadcasters, and investors alike.

For more information, visit the company’s website at www.BreraHoldings.com.

NOTE TO INVESTORS: The latest news and updates relating to BREA are available in the company’s newsroom at https://ibn.fm/BREA