California-based International Stem Cell Corporation this morning announced that its wholly owned subsidiary, Cyto Therapeutics, has signed a Letter of Intent (LOI) with Royal Melbourne Hospital in Australia to conduct phase I/IIa clinical trials of ISCO’s proprietary human parthenogenetic neural stem cells (hPNSCs) for the treatment of Parkinson’s Disease.

The LOI follows a recent meeting with Australian Therapeutics Goods Administration (TGA), and precedes a full agreement expected to be signed after TGA and the HREC approve the clinical protocol for the trials.

“We had a productive meeting with TGA where we discussed the clinical protocol and potentially came to an agreement on all remaining items. We look forward to receiving TGA approval for clinical trials in November and enrolling patients soon thereafter,” Russell A. Kern, Ph.D., chief scientific officer of ISCO, stated in the news release.

ISCO’s Parkinson’s disease program uses hPNSCs, a novel therapeutic cellular product derived from the company’s proprietary human pluripotent stem cells. hPNSC are self-renewing multipotent cells that are precursors for the major cells of the central nervous system. The cells’ ability to differentiate into dopaminergic neurons and express neurotrophic factors to protect the nigrostriatal system creates a potential new opportunity for the treatment of Parkinson’s disease.

Additionally, hpSCs offer the potential to create the first true stem cell bank, UniStemCell™. ISCO also produces and markets specialized cells and growth media for therapeutic research worldwide through its subsidiary Lifeline Cell Technology (www.lifelinecelltech.com), and stem cell-based skin care products through its subsidiary Lifeline Skin Care (www.lifelineskincare.com).

For more information visit www.internationalstemcell.com

According to the National Institute of Mental Health (NIMH), major depression is one of the most common mental disorders in the United States. In 2013, an estimated 15.7 million individuals aged 18 or over – roughly 6.7 percent of all U.S. adults – had at least one major depressive episode. For these individuals, finding relief can be difficult. The American Academy of Family Physicians reports that up to two-thirds of all patients diagnosed with major unipolar depression will not respond to the first medication prescribed. If the second form of treatment also fails to produce a significant clinical improvement, the patient’s depression may be considered resistant to treatment. At this point, individuals have traditionally had extremely limited options for conquering this debilitating condition.

VistaGen Therapeutics, Inc. (OTCQB: VSTA), through the development of AV-101, is addressing this underserved indication. Earlier today, the company announced that it has taken a major step toward the eventual commercialization of its innovative drug candidate by dosing the first patient in its ongoing phase IIa study of AV-101 for treatment-resistant major depressive disorder (MDD). The study, which is being funded by the NIMH, is expected to enroll between 24 and 28 adult patients in order to evaluate the efficacy and safety of a single oral dose of AV-101 administered once daily for two weeks.

“We are pleased to have achieved this important milestone, notably advancing our AV-101 clinical development program, and we look forward to working closely with the esteemed leadership team at the NIMH,” Shawn Singh, chief executive officer of VistaGen, stated in a news release. “We believe that AV-101’s differentiated mechanism of action, oral availability, strong preclinical efficacy and excellent clinical safety profile support AV-101 as a potentially transformative treatment for millions of patients with MDD who are inadequately served by standard antidepressant therapies.”

In previous clinical testing, AV-101 has exhibited a host of sustained anti-depressant effects that exceed the effectiveness of currently available medications in the multi-billion dollar global antidepressant market – including serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs). While SSRIs and SNRIs must be taken for several weeks before patients experience significant therapeutic benefits, AV-101 has demonstrated robust and rapid antidepressant effects similar to the benefits of ketamine without the high potential for abuse and psychosis-like behavioral side effects.

With its phase IIa study now underway, VistaGen expects top-line data in the first half of 2017. For prospective shareholders, the company’s progress toward the commercialization of its groundbreaking drug candidate makes it an intriguing investment opportunity in the coming months. Look for VistaGen to continue to benefit from its collaboration with the NIMH as it progresses toward a potentially transformative advancement in the treatment of MDD.

For more information on the company, visit www.vistagen.com

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OurPet’s Company created quite the stir this morning when the company reported a triple-digit increase in quarterly net income on an impressive hike in revenues. While the company primarily attributes the growth to stronger domestic and international sales partnerships, one can’t ignore innovation as a considerable catalyst.

In recent years, the nation’s overall $73 billion pet products industry has enjoyed robust growth driven by increasing e-commerce purchases and an uptick in dog and cat ownership. The market is currently dominated by PetSmart, Inc. (NASDAQ: PETM) (nearly 39%), which tallied full-year 2014 revenues of $1.9 billion, and Petco (roughly 19%), which is looking raise about $800 million in an IPO in the relatively near future, according to Bloomberg Business. The two leaders are also reportedly in discussion for a merger, but there’s plenty of room for an innovative player like OurPet’s.

When OurPet’s jumped into the pet specialty business nearly 20 years ago, there was an obvious lack in product innovation and new product development. It’s within this void that the company initially focused its sights and has continued to excel. In the last five years, OurPet’s used this focus as an anchor during its transition from a small to a medium-sized company. Today, OurPet’s has an intellectual property portfolio featuring more than 160 individual patents.

The overarching ongoing capitalization strategy is to execute the aggressive development of innovative products to successfully push through adverse market conditions to achieve increases in revenue, margins and net income.

By maintaining an active new product development program built on these patents, and a proven history of churning out and bringing to market evolutionary and revolutionary products, OurPet’s enjoys global sales via specialty retailers, food, drug and mass chains, and e-commerce and international channels. A look at the company’s third-quarter results demonstrates the efficiency of this model.

OurPet’s this morning reported record third-quarter revenue of $5.99 million, an increase of 7% from $5.60 million in revenues for the comparable three months of 2014. Net income for the third quarter increased 428% to $410,450, or $0.02 diluted earnings per share, compared to $77,751, or $0.00, for the year prior.

For comparison, in March, PetSmart reported a 6.0% increase in fourth quarter 2015 sales and an increase of 8.7% increase non-GAAP net income over the prior year.

Commenting on its impressive quarterly performance and innovation behind the growth, Dr. Steven Tsengas, OurPet’s president and CEO, stated, “We are pleased with our results for the third quarter in which we achieved record net revenue, gross margins improving to 34%, and net income from operations of almost 11% of sales. We continue to see strong sales growth in the Pet Specialty channel driven by our cat toys and bowls/feeder lines. E-commerce sales rebounded and grew 7% while the Food, Drug, Mass channel slightly decreased; however, we anticipate improved sales as the conversion to the Pet Zone brand is completed by year end… With the recent and anticipated introduction of a significant number of new innovative products in all our product categories, we are experiencing robust sales activity. Our Catty Whack™, winner of the SuperZoo ‘Best New Cat Product’ award, is beginning to ship and is receiving strong consumer reaction. We expect to release more information on other major, trend-setting products over the next six months.”

In its news release this morning, OurPet’s alluded confidence in its ability to maintain growth momentum moving forward. The company continues to dig its heels into the innovation-thirsty pet industry to capture its fair share of the market and deliver new products poised to take the industry by storm.

For more information visit www.ourpets.com

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Today’s English language learners have access to more sophisticated tools and technology than ever before, but that doesn’t mean that there’s nothing to be learned from the eager students of the past. In a recent news report, Nageen Mustafa, a Syrian refugee with surprisingly strong English skills, recounted how she learned English by watching the popular soap opera Days of our Lives, and her story is far from an isolated incident. In fact, it’s possible that Hollywood, along with its most famous characters, has done more to teach English in the developing world than any educational outreach program ever created.

The draw of films and television series is easy to understand. Instead of looking at repetitive, sometimes boring learning programs and flashcards, films such as Taxi Driver and Top Gun combine education with first-class entertainment that makes learning a new language more fun. Industry research has confirmed this hypothesis, with bimodal input – which includes both sound and video – consistently increasing comprehension and vocabulary in English language learners more effectively than less engaging techniques. Lingo Media Corporation (OTCQB: LMDCF) (TSX-V: LM), through subsidiary ELL Technologies, is putting this research to good use with its groundbreaking Speak2Me learning platform.

With Speak2Me, Lingo Media leverages its large library of digital content to create customized curriculums that suit the specific needs of its customers. The company has already secured contracts for this technology with a collection of diverse organizations – including municipal governments in Colombia, the University of Guadalajara in Mexico, the Peruvian Navy and the National Training Service (SENA) in Colombia.

“Learning English in an easy to use digital format is essential, especially for the military, government, corporate and academic industries,” Gali Bar-Ziv, president and chief executive officer of ELL Technologies, stated in a news release. “Through our large digital learning library, we are able to quickly and seamlessly build custom digital solutions based on the client’s needs.”

Building on the success of old VHS cassettes and subtitled movies, Lingo Media is continuing to progress toward its goal of changing the way the world learns English. As it expands its foothold in the pivotal Latin American learning markets, the company is in a formidable position to establish a sizable and sustainable presence in the evolving market for English language learning solutions in developing markets around the globe.

For more information, visit www.lingomedia.com

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Achieving sustainable growth in any industry depends on the ability of a company’s management team to accurately predict evolving market conditions and address rising demand. For months, Hemp, Inc. (OTC: HEMP) has kept shareholders abreast of its progress toward commencing operation of its industrial hemp decortication facility in Spring Hope, North Carolina. As the first and only hemp processing facility to be built in the United States in nearly a century, the construction and operation of this facility demonstrated the foresight of the company’s leadership team, and the time has now come for the company to benefit from this intuition.

On October 31, North Carolina Governor Pat McCrory passed Senate Bill 313, giving farmers throughout the state the option to legally cultivate industrial hemp crops. According to the North Carolina General Assembly, a legalized industrial hemp industry “is in the best interest of the citizens of North Carolina… to expand employment, promote economic activity and provide opportunities to small farmers for an environmentally sustainable and profitable use of crop lands that might otherwise be lost to agricultural production.” In a news release, Hemp, Inc. outlined its intentions to aid in the resurrection of the pivotal agricultural industry.

“Hemp, Inc. has made a commitment to North Carolina farmers to pay 10 percent above the market price for their hemp crops, for the first year, to boost the industry and give our farmers a helping hand,” Bruce Perlowin, chief executive officer of Hemp, Inc., stated in the news release. “We want to support and encourage the small family farm and non-GMO, certified organic hemp production.”

With legalization secured, the company is now progressing toward the impending start of production at its decortication facility. When complete, Hemp, Inc. will process hemp to sell to textile manufacturers and other users. The company’s decortication equipment can process raw hemp into two valuable base products – fiber and hurd – that can be used in the creation of hundreds of products. Hemp, Inc. has also outlined plans to build a testing lab within its processing facility that will be used for new product development testing, as well as testing of raw hemp materials, fibers and products. When completed, the lab will be the first of its kind in the U.S.

Through these measures, Hemp, Inc. will look to usher in a new era in domestic industrial hemp production, providing the company with a strong platform for sustainable financial growth. This optimism has been echoed by the markets. Since Senate Bill 313 passed, Hemp, Inc. has transformed into one of the top traded stocks on the OTC markets. Just after the opening bell, the company’s shares recorded a price increase of more than 113 percent. Moving forward, Hemp, Inc. will look to build on this progress while continuing to establish a strong position in one of the country’s most rapidly evolving industries.

For more information, visit www.hempinc.com

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Today before the opening bell, OurPet’s Company reported record third-quarter revenue of $5.99 million, an increase of 7% from $5.60 million in revenues for the same three-month period a year earlier. Net income for the quarter increased 428% to $410,450, or $0.02 diluted earnings per share, compared to $77,751, or $0.00, for the year prior.

Dr. Steven Tsengas, President and CEO, stated, “We are pleased with our results for the third quarter in which we achieved record net revenue, gross margins improving to 34%, and net income from operations of almost 11% of sales. We continue to see strong sales growth in the Pet Specialty channel driven by our cat toys and bowls/feeder lines. E-commerce sales rebounded and grew 7% while the Food, Drug, Mass channel slightly decreased; however, we anticipate improved sales as the conversion to the Pet Zone brand is completed by year end. Unfortunately, with the strengthening of the U.S. dollar, international sales have been negatively impacted particularly in Canada and the United Kingdom.”

Dr. Tsengas added, “We have expanded and strengthened our relationship with several domestic and international independent sales representative organizations, and have added another experienced salesperson to our staff. With the recent and anticipated introduction of a significant number of new innovative products in all our product categories, we are experiencing robust sales activity. Our Catty Whack™, winner of the SuperZoo ‘Best New Cat Product’ award, is beginning to ship and is receiving strong consumer reaction. We expect to release more information on other major, trend-setting products over the next six months.

“As we have previously communicated, the last five years have been challenging for OurPet’s as we have transitioned from a small- to a medium-sized company poised for accelerated future growth in both revenue and net income. This required large investments in management/operating informational systems; strengthening and, where appropriate, adding management and professional/technical talent; improving warehousing and inventory management efficiencies; strengthening relationships of strategic domestic and overseas suppliers; and strengthening our relationship with our banking resources. We sincerely believe that these improvements will positively impact revenue and profit results going into the fourth quarter of 2015 and beyond.”

2015 Third Quarter Results

Net revenue increased 7% to $5,986,645 for the 2015 third quarter versus the same period last year. The $386,000 increase was attributable to strong sales in the Pet Specialty and Value channels, partially offset by a decrease in the Food, Drug and Mass channel.

Gross Profit was $2,012,177 for the 2015 third quarter compared to $1,640,751 the prior year. Gross profit margin increased 4.3 percentage points to 33.6% for the 2015 third quarter from 29.3% for the same period a year ago due to continuous improvement initiatives, price increases, and product mix.

Income from operations increased to $649,023 for the 2015 third quarter from $152,768 a year ago. This increase was primarily due to higher gross profit and also benefited from lower selling, general, and administrative expenses.

Other income for the 2015 third quarter increased to $14,582 from $6,051 a year ago due to a higher amount of patent infringement settlements.

Income before taxes was almost five times greater at $627,686 for the 2015 third quarter compared to $127,666 a year ago.

Income tax expense for the 2015 third quarter increased to $217,236 from $49,915 a year ago due to the higher income.

Net income increased to $410,450 for the 2015 third quarter from $77,751 last year. Net income per diluted share increased to $0.02 for the third quarter of 2015 from $0.00 a year ago.

EBITDA was $825,696 for the 2015 third quarter versus $323,140 a year ago. A reconciliation of EBITDA to GAAP net income is provided in an attachment to the summary financial statements.

2015 First Nine Months Results

For the first nine months of 2015, net revenue increased 6% to $17,170,795. The growth was attributed to strong Pet Specialty sales, especially in the bowls and feeders category.

Gross profit increased 15% to $5,424,591 for the first nine months of 2015 versus the prior year. Gross profit margin increased 2.5 percentage points to 31.6% for the first nine months of 2015 from 29.1% the prior year due to the same factors that benefited the 2015 third quarter results.

Income from operations increased 143% to $1,427,797 for the first nine months of 2015, which was attributable to higher gross profit and lower selling, general, and administrative expenses.

Other income decreased to $40,582 for the first nine months of 2015 from $77,713 for the same period last year due to a greater amount of patent infringement settlements in 2014.

Income before taxes increased to $1,383,158 for the first nine months of 2015 compared to $566,658 for the same period a year ago.

Income tax expense was $496,839 for the first nine months of 2015 compared to $206,723 the prior year.

Net income for the first nine months of 2015 more than doubled to $886,319 from $359,935 for the same period in 2014. Net income per share increased to $0.04 for the first nine months of 2015 from $0.02 last year.

EBITDA increased 72% to $1,984,688 the first nine months of 2015 compared to $1,153,656 the prior year. A reconciliation of EBITDA to GAAP Net Income is provided in an attachment to the summary financial statements.

The Current Ratio improved to 5.61, reflecting strong liquidity, while Stockholders’ Equity improved by $904,319 or 12.1% over the comparable date last year.

For those unfamiliar with OurPet’s Company, the company develops, produces and markets various pet accessory and consumable products designed to awaken pets’ natural instincts, be it in feeding, playing or waste management. Sold globally through pet specialty retailers, food, drug and mass chains, e-commerce and international channels, the company’s products are marketed under a the OurPets®, Pet Zone® and PetTastic® brands with well-known sub-brands such as Play-N-Squeak™, Cosmic Catnip™, Durapet, SmartScoop and Flappy.

To learn more about OurPet’s Company, visit www.ourpets.com

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Neah Power Systems, developer of innovative power solutions for a range of applications, is one of the companies trusted by today’s high-tech military to provide energy where it’s needed, no matter how demanding the situation. Technology has transformed the military, with the world’s most advanced computational and communications equipment, but all that technology is of no value in the field without reliable power to keep it running, and Neah Power has differentiated itself with patented and award-winning designs that do exactly that. It can be said that energy, portable and dependable, is as critical in today’s military as horses were to 19th century cavalry.

The conditions under which military equipment, and associated power systems, are expected to operate are a world apart from normal consumer oriented environments, a market that Neah Power also effectively serves. The company’s patented silicon-based fuel cell is unique in its ability to provide two to three times the energy capacity offered by the standard BA-5590 battery, while maintaining a highly compact form. In addition, fuel cell technology means virtually instant recharging, since a soldier can quickly insert a new lightweight fuel cell cartridge into the fuel cell. Soldiers only need to carry one fuel cell, versus multiple bulky and heavy batteries. Neah Power technology means major weight and volume reductions over traditional widely-used portable military power sources, representing a huge market.

The vast world military market is just one of Neah Power’s growing targets. The company also develops disruptive energy technologies for global opportunities supporting first responders, logistics, as well as consumer electronics and mobile markets. Emergency responders are served by Neah’s PowerChip and BuzzCell technologies. Cordless hand-held devices are important for efficient logistics, and Neah’s products serve companies of every size. The unrelenting demand for improved battery life for mobile computing is served by Neah’s BuzzBar and associated family of products.

In a world hungry for energy that is long-lasting, compact, reliable, and lightweight, Neah is the better mousetrap.

For more information on Neah Power Systems, visit www.neahpower.com

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ContentChecked is the developer of MigraineChecked, SugarChecked and ContentChecked, an innovative family of health apps designed for individuals with dietary restrictions and/or food intolerances or preferences. As consumer awareness of its apps continues to rise, the company is also finding itself in other invaluable spotlights. ContentChecked’s SugarChecked app was recently featured in Reviewed.com, a division of USA Today.

Reviewed.com is a consumer-oriented site that delivers comprehensive reviews conducted by a panel of product experts. Read the full article here: Cutting Back on Sugar? There’s an App for That.

The article notes the high sugar intake of the average American, despite mounting research that links high sugar consumption with obesity, cardiovascular disease, dementia, macular degeneration, tooth decay and Type 2 diabetes.

“A big part of the problem is that sugar is hidden in many of today’s processed foods. That’s where a new app called SugarChecked may come in handy. SugarChecked lets shoppers scan product barcodes at the grocery store to reveal detailed sugar content information. The app identifies four main types of sugars that consumers can avoid … As well as unmasking often-deceptive food labels, SugarChecked provides shoppers with recommendations for healthier alternatives in real time,” reads the article.

After further describing the technology and its features, the article concludes with sugar intake recommendations from the American Heart Association and lists several foods with “hidden” sugars – validating the value of ContentChecked’s full suite of apps.

For more information, visit www.contentchecked.com

Hemp, Inc. this morning issued an update regarding the ongoing push for legalization of industrial hemp in North Carolina, along with rising interest and awareness of the Hemp, Inc. brand, subsidiary and decortication facility.

In the news release, Hemp, Inc. cites an article in The News and Observer written by Colin Campbell, which reports that industrial hemp could be legal in North Carolina tonight. As previously reported, the Industrial Hemp Bill in North Carolina (Senate Bill 313) passed the state’s House and Senate last month and now awaits Governor Pat McCrory’s signature. According to The News and Observer article, unless the governor vetoes it before midnight, it will become law without his signature at midnight Friday.

Campbell also references Hemp, Inc.’s multipurpose industrial hemp processing facility in Spring Hope, North Carolina, writing that North Carolina is “home to one of the country’s only decortication plants, a facility that processes hemp to sell to textile manufacturers and other users. The multimillion-dollar plant is set to start production within months at a cavernous warehouse outside the small Nash County town of Spring Hope.”

Once legalized, North Carolina will be home to the only industrial hemp commercial decortication facility in the United States – and Hemp, Inc. will be at the forefront of this important breakthrough. While many other had abandoned the belief that North Carolina would legalize hemp, Hemp, Inc. CEO Bruce Perlowin stayed firm to his belief otherwise and kept his plant in the state.

“We were being wooed to move the plant to South Carolina, Kentucky, Colorado, and even Canada,” he says. “However, I knew the legalization of industrial hemp in North Carolina could not be that far off. We would happily process the millions of pounds of kenaf, inherited with the purchase of the decortication equipment, while we waited for hemp to be legalized. And now, it seems that day starts at midnight for the state of North Carolina.”

David Schmitt, COO of Hemp, Inc.’s subsidiary, Industrial Hemp Manufacturing, LLC was also featured in a video explaining the manufacturing process of the decortication facility and what the company expects to accomplish once the clock strikes 12.

The company has also rebuilt one of its two mills, to be used in the manufacture of Drillwall LCMs. The first of the portable decortication plants have also arrived at Hemp, Inc.’s facility, which will allow Hemp, Inc. to help farmers decorticate their crops in states too far away to utilize Hemp, Inc.’s processing facilities.

Hemp, Inc. also said it will build a testing lab to house new product development testing and testing raw hemp materials, fibers and hemp-based products. This will position the company’s decortication facility as the nation’s only commercial testing lab for industrial hemp.

Bob Hughes, VP of Hemp, Inc.’s Sales and Marketing, said, “I don’t know of any other industrial hemp testing labs in North America except in Manitoba and other places in Canada… none here in the United States. We will be the first. Additionally, as the plant approaches the final phase of completion, we are reaching out to our contacts, which are some of the largest petroleum, oil and gas companies in the world. We will truly be the leaders of the industrial hemp industry.”

The testing lab and equipment will enable the production of bio-based polymers, and a powdery kenaf or hemp substance, a key component in products that will be produced in the facility. All of the raw materials will also be a natural, organic alternative to chemical-based compounds.

“What we will be manufacturing is what you would consider ‘food grade’… natural, bio-organic and non-toxic. We do everything green and will be testing for the quality of products we produce. Quality assurance is our primary goal for our customer base,” said Hughes.

Striving to update the public on hemp, its many uses, and the company’s operations, Industrial Hemp Manufacturing, LLC on November 4, 2015, will host the Weed 4 Warriors at its facility in Spring Hope. Weed 4 Warriors will be given a plant tour, and Q&A time after educating them on the vast number of products that can be manufactured from Industrial Hemp.

For more information visit www.hempinc.com

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Regardless of how well-mannered little Johnny and Suzy are, there’s something about a trip to the mall that has a way of changing their demeanor in the blink of an eye. This behavioral phenomenon transforms what should be a relaxing shopping experience for the entire family into a physical and emotional tug-of-war for everyone who gets into and pops out of the minivan in row R34. The net of the story is that if you want to take little Johnny and Suzy out someplace for an exclusive, youthful event, the market offers a limited number of options.

As for food, a menu made up of high-quality organic food amid an environment with a casual dining area for adults, and a huge play area for the little ones, is the model Giggles N’ Hugs has been executing on rather successfully in Los Angeles for over two years. Parents can now relax while their children get healthy exercise while enjoying the themed Gymboree-like play area. Giggles N’ Hugs is experiencing rousing applause from patrons and mall owners at its three locations in upscale shopping centers around LA. It comes as no surprise that many Hollywood celebrities have taken their kids to eat and play at these GIGL locales.

Parents welcome GIGL’s high-end organic dishes versus the traditional mall fare – carbohydrate and sugar laden fast-food. Phrases like ‘unlimited potential’ mark the description of what is truly a unique and practical restaurant concept. What’s more is that shareholders point to the recent Q2 filings for promising financial data which shows increasing sales volume and intrigue with the company’s themed birthday parties. Further, private party rentals were noted trending upward in Q2, with year-over-year gains of 3.4 percent.

Giggles N’ Hugs, Inc. owns and operates a restaurant in the Westfield Mall in Century City, a restaurant in the Westfield Topanga shopping center in Woodland Hills, and a restaurant in the Glendale Galleria in Glendale, California. Giggles N’ Hugs was founded in 2010 and is based in Los Angeles, California.

For more information on the company visit www.gigglesnhugs.com

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