International Stem Cell Corp. (OTCQB: ISCO) is considered among industry experts as a leader and pioneer in the field of regenerative medicine as a result of its development of a new class of stem cells. These cells, known as human parthenogenetic stem cells (hpSCs), possess the best characteristics of each of the other classes of stem cells. These stem cells are created by way of chemically stimulating the oocytes (eggs) to begin division. The oocytes are not fertilized and no viable embryo is created or destroyed. The ethical advantage of derivation from unfertilized oocytes makes these stem cells a promising source for the cell-based therapeutics industry.

ISCO is a biotech company that funnels its endeavors toward the development of therapeutic and biomedical products on a global scale. The company’s products are based on human parthenogenetic stem cells, a proprietary type of pluripotent stem cells. Additionally, the company develops neural stem cells, which are commonly used in the treatment of Parkinson’s disease (PD) and a variety of other neurological disorders.

Studies on the amount of money spent annually on the treatment of PD are nothing short of stunning. It is estimated that the combined direct and indirect costs of PD in the U.S. – which include treatment, social security payments and lost income due to the patient’s inability to work – is in the range of $25 billion. Medication costs for an individual afflicted with this disease average $2,500 a year. Furthermore, The Parkinson’s Disease Foundation has estimated that therapeutic surgery can cost up to $100,000 per individual.

Caused by the death of dopamine-producing cells in a brain region called the substantia nigra, PD typically results in severely restricted movement. Today’s treatments focus primarily on replacing the lost dopamine, but these treatments eventually fail, as the dopamine-making cells continue to die. It is through this process that stem cell therapy is of particular interest. Stem cell research has the potential to positively impact the development of disease-modifying treatments for PD. Enormous progress has been made in the area of creating dopamine-producing cells from stem cells, while the development of new cell models of PD has created a promising area of stem cell research as a whole.

For more information, visit www.internationalstemcell.com

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Earlier today, Oakridge Global Energy Solutions, Inc. (OTCQB: OGES) announced a new partnership with IST Co. Ltd, a Tokyo, Japan-based firm with broad relationships in the power and stored energy industries. Through this collaboration, the IST team will join the current Oakridge advising team through its previously established subsidiary in Hong Kong. IST is expected to leverage its broad relationships with university and research organizations throughout Japan and around the world in order to provide Oakridge with ongoing access to joint technology development opportunities for next generation rechargeable lithium batteries, such as lithium air, lithium-sulfur, nano-silicone and graphene negative electrodes, in addition to aiding in efforts to commercialize Oakridge’s previously developed thin film solid state lithium battery technology.

“We are all about latest technology and products at Oakridge,” Steve Barber, the company’s executive chairman and chief executive officer, stated in the news release. “With IST complementing the existing Oakridge advising team in Japan we have now greatly expanded our presence and relationship with Japan, while at the same time providing a much higher quality of equipment and raw materials for building our battery systems.”

With this partnership in place, Oakridge is better positioned to work with the highest quality Japanese equipment manufacturers in order to support future growth of its recently launched manufacturing facilities in the United States. The company expects the addition of top notch advisors and consultants to allow Oakridge to maintain its already high standards of technological advancement while continuing to drive innovation in its product line and address the evolving needs of its customers with the latest technology in high power battery and portable energy systems.

“We at Oakridge regard our relationship with Japan as highly important because of its technical prowess and also because it is a very strong ally to the United States and Australia which will be vitally important in the increasingly tumultuous international geopolitical situation,” continued Barber. “We are excited to be working with the high caliber of people and companies that we have had the pleasure to meet in the Japanese lithium ion battery market.”

The announcement of a partnership with IST caps off what has been an eventful week for Oakridge. On Monday, the company heralded the successful results of recently completed field trials of the Man-Portable Tactical Autonomous System (MANTAS), which was designed and produced by Maritime Tactical Systems, Inc. (MARTAC). Oakridge’s specialized, high performance batteries “greatly expanded the effective range of the MANTAS while at the same time providing us a much safer vessel,” according to MARTAC president and CEO Bruce Hanson. On Wednesday, Oakridge announced an agreement to supply batteries to Freedom Trucking for use in a fully electric interstate truck propulsion system.

For more information, visit www.oakridgeglobalenergy.com

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Moxian, Inc. (OTCQB: MOXC) has made a well-timed entry into the online-to-offline marketplace in Asia. A pioneer of novel social marketing and promotion platforms, Moxian moved into this market at a time when countries in the region are enjoying significant growth. In China alone, an estimated annual sales growth of 25% has been reported.

From its headquarters in Shenzhen, China, Moxian helps a variety of merchants – including retailers, manufacturers, shopping mall operators, transportation companies, telecommunications providers, software developers, online e-commerce operators, payment providers and news media – promote their businesses through online social media and with products such as:

• Moxian+ App – an online-to-offline business solution tailored to small and medium businesses
• MO-Promo – an online sale promotion website for the company’s merchant clients
• MO-Reward – a reward platform

Moxian’s products are designed to increase user stickiness. They are built to attract users and entice them to return regularly, as well as to encourage new users to subscribe to the company’s website. Moxian’s offerings also aim to enhance the merchant-customer interaction. The company designs products and services that allow its merchant clients to run targeted ad campaigns that utilize data compiled from a database of user activity.

Moxian has spent a fair amount of time testing, refining and perfecting its O2O platform in Asia. During this testing and development stage, the company brought in modest revenue. Now, in 2016, it is directing its attention toward the largest cosmopolitan areas in China and appears primed to see a major increase in revenue from new merchant subscriptions to its platform, as well as the opening of new sales offices in Beijing, Guangzhou and Shanghai.

Steered by a skillful management team and far-reaching business strategies, Moxian appears ready to take advantage of the substantial market opportunity available in the O2O sector in China and to advance even further. With a growing number of merchants utilizing its platform, merchant fees will likely offer a major source of recurrent revenue for the company, which is also poised to earn additional revenue from the sale of advertising on its platform.

For more information, visit the company’s website at www.Moxian.com

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Nutra Pharma Corporation (OTCQB: NPHC), the company behind innovative products such as Nyloxin® and Pet Pain-Away, is set to build on its rich history of pursuing over-the-counter sales as it continues to advance its therapeutic pipeline based on cobra toxin. In an interview with The Life Sciences Report released last October, Rik Deitsch, the company’s chief executive officer, discussed Nutra Pharma’s plan to promote sustainable growth through the development and distribution of its proven pain medications in a collection of global markets – including India, China, Canada and the United States.

“We started speaking with the FDA in 2009 about an ethical pain therapy that uses microgram doses of cobra venom extract as a neurotoxin, or neuro blocker, for pain and inflammation,” Deitsch recounted in the article. “The FDA told us our drug qualified as an OTC homeopathic medication because it is derived from a natural product and because the dosage is so small. That allowed us to create our first OTC drugs in 2009–2010.”

To date, Nutra Pharma has released seven unique stock keeping units (SKUs) of Nyloxin, which is an OTC pain treatment for humans, as well as one SKU of Pet Pain-Away for dogs and cats. Products under both of these brands leverage a non-addictive, non-narcotic formula and lack all of the negative side effects commonly associated with other OTC pain medications. Despite this stellar safety profile, Nyloxin has shown to be approximately 600 times more potent than morphine in clinical studies, offering pain relief for roughly four hours longer than the popular opioid medication.

In the Life Sciences Report article, Deitsch noted that Nutra Pharma is “at an inflection point.” Because it is able to generate significant revenues from OTC drug sales – with sales from these products expected to increase dramatically over the next 16 months, according to Deitsch – the company has effectively mitigated the risk to investors while continuing to push forward with clinical trials for a pipeline of potential blockbuster drugs addressing underserved indications such as multiple sclerosis (MS), human immunodeficiency virus (HIV), and select autoimmune and antiviral conditions. Deitsch predicts that Nutra Pharma will be cash-flow positive within the first half of 2016.

Nutra Pharma released a letter to shareholders in December providing an update on the information offered in the previously referenced article and reviewing the company’s progress toward achieving growth in 2015. Particularly worthy of note, the company was granted orphan status for drug candidate RPI-78M for the treatment of pediatric MS. With this designation in hand, Nutra Pharma will enjoy a collection of benefits over conventional drug applications – including tax credits for research costs, the option to apply for grant funding, clinical trial design assistance and the waiver of Prescription Drug User Fee Act (PDUFA) filing fees, which can be in excess of $2.5 million. In a news release earlier this month, the company announced that it will unveil additional steps related to the development of RPI-78M and other growth initiatives in the coming weeks.

For more information on the company, visit www.NutraPharma.com

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Ovarian cancer is the fourth-leading cause of cancer deaths among women in the U.S. When someone is diagnosed with ovarian cancer, they are usually in the advanced stages of the disease and treatment is not nearly as effective as it would be if it had been discovered earlier. Avant Diagnostics, Inc. (OTCQB: AVDX) is a medical diagnostic technology company that specializes in large panel biomarker screening. The company’s first test, OvaDx®, is a sophisticated microarray-based test designed to detect pre-symptomatic ovarian cancer by measuring the activation of the immune system in blood samples in response to early stage ovarian tumor cell development.

In clinical development, OvaDx has indicated high sensitivity and specificity for all types and stages of ovarian cancer, including stage IA-IV borderline serous, clear cell, endometrioid, mixed epithelial, mucinous, serous and ovarian adenocarcinoma. Upon FDA approval, Avant plans to offer its diagnostic product as an elective test for women seeking greater wellness, as well as those in the elevated risk category for ovarian cancer.

In a recent Time magazine article (http://dtn.fm/sv0Pa), there is a great comparison study done on a largely ineffective technique currently used for early detection of ovarian cancer. A blood test, called CA-125, can pick up signs of tumors in the ovaries, but it’s not very specific or sensitive for these growths. CA-125 levels can rise not just because of ovarian tumors, but during menstruation and pregnancy as well. That may explain why the test only picks up 60% to 65% of cancers.

OvaDx is expected to be used by doctors to advance the forefront of ovarian cancer treatment, promoting the utilization of improved surgical options and more effective chemotherapies by serving as a supplement to existing tests, such as CA-125, OVA1® and transvaginal ultrasound. In this way, Avant’s innovative product will promote earlier diagnoses and, as a result, improved survival rates for patients with ovarian cancer.

According to another Time magazine article (http://dtn.fm/J1Vwa), the traditional treatment for ovarian cancer is surgery followed by rounds of monthly chemotherapy. The treatment is effective, but there is growing evidence that exposing tumors to such high dose toxic agents at one time is effective in killing cancer cells in the short term, but may encourage chemo-resistant cells to flourish over time.

The common theme here is that early identification of problems (ovarian cancer in this case) is essential in order to take full advantage of currently available treatment options. Cancer is just like the ‘The Blob’ from the classic 1950’s movie and the 1980’s remake. If people would have properly identified the Blob/cancer earlier, it could have been frozen/treated and stored away so that people could have gone on with their daily lives without worry and pain.

For more information, visit the company website at www.avantdiagnostics.com

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California’s four-year drought should desiccate customer traffic, the way it has the streams and rivers, for restaurants like Giggles N’ Hugs (OTCQB: GIGL). As CEO Joey Parsi explained in a recent interview with QualityStocks, good weather is bad news for restaurants, since, when the weather is good, people do ‘outdoorsy things’. Despite the call of the outdoors, Giggles N’ Hugs saw its revenues increase. Sales were up about three percent in spite of the weather. Giggles N’ Hugs is a chain of fast casual restaurants with healthy menu options, a fun family atmosphere and, of course, plenty of giggles and hugs.

A story (http://dtn.fm/NDaL2) in Nation’s Restaurant News explained ‘Why Fast Casual is Eating the Industry’s Lunch’ by looking at Chipotle Mexican Grill (NYSE: CMG), Panera Bread Co. (NASDAQ: PNRA), Five Guys LLC, and Shake Shack (NYSE: SHAK). Another story (http://dtn.fm/1bL8v) in Forbes quotes industry analyst Technomic’s ‘2014 Top 500 Chain Restaurant Report’, noting that ‘sales for fast casual chains grew by 11% and store count by 8% in 2013’. The fastest of the fast casuals has been Chipotle which has had revenue growth of around 20 percent for the past five years. Yet another story (http://dtn.fm/M1T6x) in the Washington Post, titled ‘The Chipotle Effect: Why America is obsessed with fast casual food’, with data from market research firm Euromonitor, reports that Americans spent over $21 billion at fast casual restaurants in 2014. The Washington Post also asks what the fast casual category is. A major characteristic seems to be the price point. The average tab for a regular fast food outlet is $5; for a fast casual it is much higher, ranging from $9 – $13.

Technomic has identified ten other factors that may play a part in customer perception: overall food quality, better ingredients, wholesome food, a perception of freshness, sophisticated décor, fast service, fair prices, friendly staff, flexible offerings, and a view of the food preparation area. These are exactly the sort of things you will find at any one of Giggles N’ Hugs’ three restaurants.

Giggles N’ Hugs offers an organic, gluten-free, menu with vegetarian options. All produce is grown locally with organic ingredients when available. The beef comes from grass-fed cows to which no hormones have been administered. Breads are made fresh daily by local artisan bakeries. At Giggles N’ Hugs, there are no leftovers; meals are prepared from scratch daily to ensure freshness. The cooks use only trans-fat free canola oil and extra virgin oil, when necessary.

The Giggles N’ Hugs menu offers appealing appetizing adventures. To start the day, you can have Caprese, a delightful concoction of ripe tomatoes, basil and fresh buffalo mozzarella drizzled with olive oil, balsamic glaze, salt and pepper, or, perhaps, the Citrus Tuna Salad, made with citrus mayo, almonds and raisins served over a bed of organic mixed greens and shredded organic heirloom carrots tossed in lime vinaigrette. For lunch, there is the Chicken Breast Parmesan, which includes grilled or breaded chicken breast topped with house-made marinara sauce, melted mozzarella and parmesan cheese that’s served with spaghetti marinara. Giggles N’ Hugs only uses all-natural chicken.

According to a research report published by Duff & Phelps entitled Restaurant Industry Insights 2015, chicken is the new ‘burger’. The reports details that, in 2013, ‘Chick-fil-A surpassed Kentucky Fried Chicken (KFC) as the top chicken fast food chain with sales of $5.0 billion compared to KFC’s $4.2 billion. This is despite KFC having more than double the number of U.S. stores (4,491) than its Atlanta-based rival (1,775). The driving factor behind Chick-fil-A’s success is actually quite simple: the chicken sandwich. Chick-fil-A doesn’t serve processed chicken patties like its fast food competitors do.

The financial menu at Giggles N’ Hugs is equally attractive. An investment report by the Small Cap Network says the projected payback period on a new store’s initial investment is only about 2.14 years. EBITDA margin after four years of a new store’s operation is expected to be close to 18 percent of sales. From an investment point of view, Giggles N’ Hugs looks very palatable.

Learn more by visiting www.gigglesnhugs.com

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Content Checked Holdings, Inc. (OTCQB: CNCK), the company behind the innovative ContentChecked, MigraineChecked and SugarChecked mobile applications, continues to secure coverage in popular online health and wellness media outlets. On Monday, it built on its recent progress when Tory Tedrow, a registered dietitian with the company, was interviewed for an article on Simplemost. The piece, titled “7 Ways To Trick Yourself Into Eating Less And Get Portion Sizes Under Control,” included helpful tips for people looking to cut down on portions without sacrificing on satisfaction.

In the article, Carina Wolff, a Simplemost contributor, suggests drinking more water as one way to prevent overeating, and Tedrow reinforced this theory. “Ensuring you’re adequately hydrated prevents dehydration-induced hunger cravings and mindless snacking,” she stated in the article. Tedrow’s comments were featured throughout the article – including tips on why you should eat from a smaller plate, put down your fork between bites and never eat ice cream straight from the carton. Wolff also included a link to the SugarChecked website for readers looking for additional assistance with avoiding unwanted ingredients.

To view the full article, visit http://dtn.fm/9qqZ2

Simplemost is an online source covering stories related to lifestyle, health, money, home, organization, food and style in support of its mission to help its readers make the most out of life. The site has a strong social media presence – including hundreds of thousands of likes on Facebook – and boasts roughly 900,000 unique monthly visitors.

With coverage on another popular online media outlet under its belt, Content Checked continues to progress toward expanding its user base and bolstering its bottom line. The company has previously announced intentions to unveil a relaunch and rebranding of its product line in the coming weeks, which will include the introduction of a new, subscription-based revenue model aimed at meeting the evolving preferences of mobile users. Following these efforts, Content Checked is expected to be in a strong strategic position to move forward with its goal of uplisting to a major exchange later this year.

For more information, visit www.contentchecked.com

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Before the opening bell, GTX Corp. (OTC: GTXO) announced the completion of a successful presentation at the SeeThruEquity & The Brewer Group 2nd Annual Innovations Investor Conference at the Ritz-Carlton in Miami on February 22. During the conference, Patrick Bertagna, chief executive officer of GTXO, gave prospective investors an in-depth look into the future of the rapidly expanding $18 billion wearable technology industry, highlighting the company’s position as a pioneer within the sector. Bertagna went on to detail GTXO’s initiatives for the coming months, which include expanding domestic and international distribution channels, launching new products and expanding its global subscriber base.

In addition to looking toward the future, Bertagna gave conference attendees insight into GTX Corp.’s recent performance by highlighting a few of the major milestones the company achieved last year. These highlights included a 405 percent year-over-year increase in revenues and a 300 percent increase in global subscribers, as compared to similar figures for 2014. In total, GTXO reports active units in the field and subscribers in more than 35 countries around the globe. The company also set the stage for future growth by enlisting four professional athletes as brand ambassadors, opening a distribution center in Ireland to better address business to consumer (B2C) demand in Europe and signing a global connectivity agreement with telecommunications giant Telefonica.

Following his presentation, Bertagna engaged in successful one-on-one meetings with institutional investors and businesses in an effort to begin identifying new opportunities and strategic partnerships that will help fuel GTXO’s growth moving forward. GTX Corp. held its shareholders meeting after the Innovations Investor Conference, on February 23 at the Parkland Golf & Country Club in Parkland, Florida. The company used this platform to further discuss its 2016 roadmap – including the benefits of recently received insurance reimbursement codes and government vendor numbers – while meeting and greeting its shareholders.

For more information, visit www.gtxcorp.com

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Elephant Talk Communications Corp. (NYSE MKT: ETAK) is a leading international provider of mobile networking software and services. The company serves the needs of several of the world’s leading mobile network operators (MNOs) and technology firms – including Vodafone (NASDAQ: VOD), T-Mobile (NASDAQ: TMUS), Zain, HP (NYSE: HPQ) and Affirmed Networks – with a comprehensive suite of applications, reliable industry expertise and high quality customer service. Elephant Talk also counts a host of mobile virtual network operators (MVNOs), enablers (MVNEs) and aggregators (MVNAs) among its customers and partners, effectively empowering global telecommunications while helping emerging players in the telecommunications industry gain a significant competitive advantage without the need for a substantial upfront investment.

With the rapid evolution of technology, the infrastructure in use by most MNOs is quickly left in the dust. The costs associated with operating and maintaining sizable network infrastructure make leading telecommunications firms think twice before adopting critical new technologies. Elephant Talk addresses legacy infrastructure challenges with its virtualized, software-based platforms. Its ET Software DNA® 2.0 platform, for example, can fundamentally change the business of an MNO or MVNO by offering significantly decreased operational costs. When combined with the ability to dramatically reduce time-to-market and improve scalability, the ET Platform helps emerging operators generate results faster than ever before at margins that support continued growth.

To fully understand the benefits of Elephant Talk’s innovative solutions for MNOs, one needs to understand how the telecommunications industry functions. In the United States, MNOs such as Verizon (NYSE: VZ), AT&T (NYSE: T) and Sprint (NYSE: S) maintain expansive nationwide networks offering service to millions of individuals. However, these networks offer more capacity than is used by the MNOs’ subscriber base. In order to more effectively leverage the capacity of an MNO network, these firms allow MVNOs to purchase excess capacity for use at wholesale rates. Some examples of MVNOs in the U.S. include Boost Mobile, which uses Sprint’s host network, and Cricket Wireless, which uses AT&T’s host network.

For new players in the telecommunications space, the costs associated with setting up a mobile network are staggering. Operating as an MVNO lowers this sizable barrier to entry, providing advantages for both MVNOs and MNOs along the way. Elephant Talk enables MNOs to create, manage and secure entire mobile networks and offer a fully equipped wholesale mobile cloud. The company’s modular system is safer, cheaper, easier to manage, more reliable and more secure than existing legacy systems. It also drives average revenue per user by offering a greater range of services, cost efficiencies and increased engagement with customers.

As an innovative MVNE, Elephant Talk also connects MVNOs to MNOs, allowing virtual network operators to offer a full suite of mobile voice, SMS and data services. The company’s technology gives MVNOs full control of their entire IT systems and network infrastructure through an intuitive cloud-based infrastructure, enabling potential cost savings of up to 90 percent and significant time-to-market advantages.

Elephant Talk empowers MVNOs and MNOs by providing a patented cloud-based mobile communications infrastructure, operating software and managed services. With a large list of clients including some of the telecommunications industry’s biggest names, the company is well positioned to build on its progress in the industry while promoting sustainable growth in the months to come.

For more information, visit www.elephanttalk.com

In a previous post, we wrote the innovative RUBICON™ solid-oxide fuel cell (SOFC) “is constructed of all solid components.” We would like to correct that statement to say that the RUBICON™ is designed to be constructed of all solid components. Also, it’s important to note that the SOFC technology can be more complex than that simple description suggests. This article clarifies the earlier statement while also giving more details on the technology and its potential.

The innovative RUBICON™ solid-oxide fuel cell (SOFC), designed by Dominovas Energy Corporation (OTCQB: DNRG), is a modular SOFC system that operates at high temperatures (800°C) and has a number of advantages. First, the RUBICON™ employs an electrochemical conversion process for power generation, which is significantly more efficient than combustion based technologies. Second, the RUBICON™ is fuel flexible and capable of reforming multiple fuels, such as natural gas, propane, LPG, diesel, landfill gas and flare gas. Third, the RUBICON™’s modular design is ideal for distributed power generation and operation at multi-MW level. Fourth, the RUBICON™ provides the flexibility of cogeneration, i.e. simultaneous generation of power and useful heat. Fifth, the RUBICON™ produces significantly less amounts of emissions on a per kWh basis. Additionally, the RUBICON™ system is silent, producing minimal noise during operation.

Dominovas’s RUBICON™ system is positioned to capture a share of a global SOFC market that’s expected to enjoy a compound annual growth rate (CAGR) of 9.78 percent over the five-year period from 2016 to 2020. Its growth is being driven by technological advances that will allow SOFC technology to be employed as an alternative to lithium-based batteries.

Dominovas Energy Corporation also has solid management components. Neal Allen is Dominovas’s chairman, president and CEO. Before becoming involved with Dominovas Energy Corporation and Dominovas Energy, LLC, where he was also CEO, he was chairman of Private Asset Group, LLC from 2002 to 2007. Emilio De Jesus is president of Dominovas. Emilio worked at Verizon Communications from 2000 to 2010 in many positions, including that of Systems Development Manager. From 2012 to 2013, he was a director of Grupo Jemilce. Dominovas’s chief operating officer is Michael Watkins. Previously, Michael was vice president and managing member of Dominovas Energy, LLC from 2007 until the merger with Western Standard Energy Group.

Dr. Shamiul Islam is Executive VP for Fuel Cell Operations. Dr. Islam is one of the foremost experts on solid oxide fuel cell technology. His expertise extends to SOFC materials, research and their development. His knowledge of the design and construction of bench scale testing systems for high temperature chemical reactions is unparalleled in the industry. He has at least two registered patents in his name. Dr. Islam worked at the University of Calvary as Postdoctoral Fellow in the Dept. of Chemical & Petroleum Engineering during the period July 2013 – April 2014. He received his PhD in Chemical Engineering from the University of Calgary, Canada.

Eric Fresh is Senior Vice President of Finance and Investments. With more than 15 years in investment banking, private equity and corporate advisory services, Eric has extensive experience in the execution of special situation transactions involving structured debt and equity financings for project finance. As Senior Vice President, Eric will lead and manage Dominovas’s capital investment and deployment program for financing the Company’s power projects. Before joining Dominovas, Eric founded E&K Partners, where he focused exclusively on value creation for middle-market companies, providing strategic management and structured finance advisory services for corporate restructurings, mergers and acquisitions, project finance and operations management. Prior to founding E&K Partners, Eric held senior positions at Morgan Stanley and Salomon Smith Barney.

With solid components like that, Dominovas Energy Corporation is poised for solid growth.

For more information, visit www.dominovasenergy.com

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