• The company has partnered with Dubai Police for the program, marking a milestone in Dubai’s strategy to integrate AI and robotics into public safety operations.
• The vehicle, named DPR-02, was engineered and manufactured in the UAE by Micropolis Robotics, and features advanced AI capabilities for surveillance, recognition, and real-time anomaly detection.
• The official deployment was inaugurated on October 15, 2025, and demonstrated at GITEX 2025, and underscores Dubai’s emphasis on homegrown innovation and smart policing technologies.

Micropolis (NYSE American: MCRP), a pioneer in unmanned ground vehicles (“UGVs”) and AI-driven security solutions, and Dubai Police have officially deployed an autonomous police patrol vehicle at Dubai Global Village, marking an important step in the Emirate’s smart policing and artificial intelligence strategy. The collaboration was formally announced on October 14, 2025, and represents one of the first real-world implementations of fully autonomous policing technologies in the UAE (https://ibn.fm/JNHLq).

The new patrol, named DPR-02, will operate throughout Dubai’s Global Village, one of the city’s busiest cultural and entertainment destinations, providing continuous surveillance and live situational intelligence to the Dubai Police Command Center.

Developed and manufactured by Micropolis Robotics, the DPR-02 integrates a suite of AI-powered systems designed to enhance public safety operations. These include vehicles, and unusual activities; a behavior analysis and suspect matrix for real-time pattern recognition; and mission planning and fleet management software that enables remote control and coordination.

The vehicle runs on Micropolis’ community autonomous software stack, which allows for fully independent navigation, obstacle avoidance, and mission execution. Using embedded AI and computer vision, the patrol can continuously monitor crowds, detect anomalies, and send alerts to human operators when intervention is needed.

According to Dubai Police, the autonomous patrol’s integration into day-to-day operations will help reduce manual workloads, improve response times, and increase safety in high-footfall public areas.

Speaking at the official inauguration, Major General Khalid Alrazooqi, Chief Information Officer at Dubai Police, said, “We would like to announce that the patrol vehicle, named DPR-02, developed for the General Headquarters of Dubai Police, will officially enter operational service starting October 15th, 2025, at Global Village. This marks the first official deployment of the vehicle, featuring all its advanced technologies.”

Alrazooqi emphasized that the project was developed entirely in collaboration with Micropolis Robotics. “The DPR-02 will continue to perform operational tasks throughout the year, supporting Dubai Police’s initiatives across the emirate,” he added. The deployment highlights Dubai’s commitment to fostering locally developed, high-technology solutions aligned with the Emirate’s long-term vision for innovation and sustainability.

Micropolis Holding has been expanding its portfolio across security, industrial, and infrastructure sectors. The company’s technology combines mechatronics, embedded systems, and autonomous AI software, allowing it to deliver complete end-to-end solutions from design to deployment.

Fareed Aljawhari, Founder and CEO of Micropolis Robotics, described the collaboration as a milestone for both the company and the UAE’s technology ecosystem. “We are proud to partner with Dubai Police in bringing this technology to life. This collaboration demonstrates how UAE-born innovation can transform the way cities approach public safety and intelligent mobility,” Aljawhari said.

He added that the DPR-02’s deployment represents “just the beginning” of Micropolis’ roadmap for autonomous mobility solutions in urban environments. The company aims to expand its offerings to include multi-purpose UGVs for industrial inspection, logistics, and critical infrastructure security.

The launch of the DPR-02 patrol fits within Dubai’s broader Smart City and AI 2031 strategies, which seek to embed artificial intelligence across public services, law enforcement, and urban infrastructure. Dubai Police has been an early adopter of such technologies, previously introducing smart police stations and robotic service assistants, and the new autonomous patrol represents a further evolution of that vision.

By leveraging AI and machine learning, the DPR-02 can process large volumes of environmental data in real time, providing actionable insights that support faster and more accurate decision-making. Its remote fleet management system enables a small number of operators to supervise multiple patrol units simultaneously, a feature that could significantly improve operational scalability.

The autonomous patrol made its public debut during GITEX 2025, one of the world’s largest technology exhibitions held annually in Dubai. Visitors, including government officials and global technology leaders, witnessed live demonstrations of the DPR-02’s autonomous navigation and AI-based detection capabilities.

The exhibition also served as an opportunity for Dubai Police and Micropolis to highlight the importance of human-machine collaboration in the future of urban policing. With autonomous policing now entering active service, the company is well positioned to capitalize on global interest in AI-enabled public safety and security solutions.

For more information, visit the company’s website at www.Micropolis.ai.

NOTE TO INVESTORS: The latest news and updates relating to MCRP are available in the company’s newsroom at https://ibn.fm/MCRP

• Izotropic highlights recurrent challenges in current breast imaging technologies and the need for high-resolution, true 3D imaging
• The IzoView breast CT scan technology is created for accurate, compression-free imaging for women who have dense breast tissue
• Increased screening demands and regulatory momentum underscore the opportunities for dedicated breast CT solutions
• IZOZF’s innovative approaches highlight the company’s mission to improve diagnosis, detection, and care for people globally

Izotropic (CSE: IZO) (OTCQB: IZOZF) (FSE: 1R3), a medical device firm leading imaging-based solutions for better diagnosis, screening, and treatment of breast cancer patients, is bringing the challenges of current screening systems and the unique potential of the IzoView Breast CT Imaging solutions as part of efforts to mark Breast Cancer Awareness Month (ibn.fm/Hml57).

Breast cancer accounts for a third of cancer diagnoses among American women, making the need for better imaging solutions critical. Current solutions like tomosynthesis, mammography, and ultrasound are limited by tissue overlap, compression, and a high rate of false positives. These issues are quite common among women with dense breast tissue, a situation common among over 50% of women within the screening-age group. 

The firm’s IzoView Breast CT was created to solve these issues. IzoView can capture about 500 high-resolution images in less than 10 seconds with the patients lying face down and without breast compression. Studies at UC Davis, where the initial breast CT technology was created and licensed exclusively to Izotropic, have revealed malignant masses to be more obvious on optimized breast CT than on DBT or mammography, with a spatial resolution reaching 100 times more than magnetic resonance imaging. 

Izotropic’s strategy attempts to close the gap between MRI and digital breast tomosynthesis, giving imaging centers and hospitals a better, mid-range option that boosts the accuracy of detection, devoid of the attendant complexity and cost of MRI technology. IzoView’s projected price of USD $500,000 means it will be adopted across the healthcare ecosystem.

With regulatory organizations like the U.S. Preventive Services Task Force and the FDA scaling up efforts in ensuring better imaging for women with dense tissues, Izotropic’s solution perfectly syncs with policy directions and emerging clinical needs. Recent mandates in America necessitate breast density notifications after mammography, highlighting the urgency and market opportunity for better imaging options.

With a core focus on the breast imaging industry, Izotropic is changing the way diagnosis and the comfort of patients are provided. These updates highlight the firm’s vision to empower clinicians with next-gen imaging tools that help improve patient outcomes and diagnostic confidence and save human lives.

For more information, visit the company’s website at www.IzoCorp.com.

NOTE TO INVESTORS: The latest news and updates relating to IZOZF are available in the company’s newsroom at ibn.fm/IZOZF

• Micropolis recently participated in GITEX GLOBAL 2025, one of the most iconic and established tech exhibitions on the planet.
• The company showcased many of the company’s latest innovations in unmanned ground vehicle (“UGV”) technology.
• This includes the Robotic Forestry Unit, the M0-2 Border Unit, and several others.

Micropolis Holding (NYSE American: MCRP), a pioneer and developer of AI-driven security solutions and unmanned ground vehicles (“UGVs”), recently appeared at GITEX GLOBAL 2025 to show off new technology (https://ibn.fm/XUbFD).

The GITEX GLOBAL 2025 event (https://www.gitex.com/), which took place at the Dubai World Trade Centre, is one of the largest and most established tech exhibitions on the planet. The event is attended by over 200,000 tech executives from more than 180 countries and features 6,500 exhibiting companies.

Micropolis was represented by their CEO and Founder Fareed Aljawhari. The UGV technology innovations covered by the company include:

• The M0-2 Border Unit, an advanced UGV designed for borders and other challenging environments. It helps with deterrence, security, and surveillance
• The M0-2 Platform, an adaptable base platform that has multiple applications
• The Dubai Police M0-1 Patrol, an AI-driven law enforcement patrol vehicle
• The Dubai Police M0-2 Patrol, the next-generation patrol solution for residential and commercial security, with a more compact design than the M0-1

These vehicles and platforms help drive the company’s mission to transform how the world approaches mobility and security, improving strategic readiness and safety in difficult high-impact situations and environments.

About Micropolis Holding Co. (NYSE American: MCRP)

Micropolis Holding Co. is a robotics and AI company that develops UGVs and mobility platforms. The company’s core technology is focused on adaptability, which lets MCRP create and deploy scalable robotics solutions for a variety of industries.

For more information, visit the company’s website at www.Micropolis.ai.

NOTE TO INVESTORS: The latest news and updates relating to MCRP are available in the company’s newsroom at https://ibn.fm/MCRP

Date: November 5-6, 2025
Location: Greater Miami, Florida
Website: https://www.futuristconference.com/
Side Events: https://luma.com/futurist_conference

The 8th Annual Blockchain Futurist Conference Week takes place November 5–6, 2025, at the stunning DAER Dayclub and Nightclub inside the Hard Rock Guitar Hotel & Casino in Hollywood, Florida. Touted as the largest Web3 event in the U.S. this fall, the conference brings together industry leaders to explore the future of Web3, crypto, AI, RWAs, DeFi, and beyond.

A hallmark of Futurist is its commitment to creating a fully immersive experience. The team loves hosting side events right onsite and nearby to keep the community connected while offering multiple stages, tracks, educational sessions, and endless networking opportunities.

The Florida edition will continue this tradition with a full week of activations, mixers, and experiences designed to connect attendees in unforgettable ways. You can register for all side events on the Futurist Conference Luma Page, and below is your ultimate guide to what’s happening throughout the week.

Optio Happy Hour
Wednesday, November 5
Entice Nightclub at The Hard Rock
Register here: https://luma.com/Optio_HappyHour

Join Optio and Parler for an evening of networking, refreshments, and conversation during the Blockchain Futurist Conference at the Hard Rock in Fort Lauderdale. This gathering is designed to bring together executives, innovators, and community members who are shaping the future of Web3.

VIP Rum Bar by Cayman Finance and Highvern
Wednesday, November 5
DAER Dayclub at The Hard Rock (VIPs only)
Register here: https://luma.com/CaymanFinance_RumBar

Cayman Finance and Highvern invites VIP guests to unwind and connect in style in the VIP Cabana at Blockchain Futurist Conference. Step into a tropical escape with handcrafted rum cocktails, live steel drum music, and an atmosphere designed for meaningful networking among leaders in blockchain, fintech, and global finance.

Access is limited to VIP Blockchain Futurist Pass holders.

ETHWomen Florida
Wednesday, November 5
9:30 AM – 2:30 PM
Entice Nightclub at The Hard Rock
Register here: https://luma.com/ETHWomen

The 4th Annual ETHWomen is a free, female-focused, and inclusive event happening in person on November 5-6, 2025! This event invites women to dive into the world of Web3 through an educational program featuring inspiring speakers, hands-on learning, and valuable networking opportunities. Open to all skill levels, ETHWomen creates a welcoming space for women to explore blockchain technology, cryptocurrency, AI, DeFi, and more.

Argentum AI Presents: AI Futurist Conference
November 6, 2025
10:00 AM – 3:00 PM
Argentum AI Stage at Entice
Register here: https://luma.com/AI_Futurist25

Join us at the AI Futurist Conference, an official segment of Blockchain Futurist Conference, on Thursday, November 6, 2025. This immersive program unites AI pioneers, Web3 innovators, and industry leaders for expert-led sessions and panels exploring how artificial intelligence and blockchain are transforming the future.

Book Signings at Futurist & ETHWomen
Wednesday, November 6
10:00 AM – 11:00 AM
DAER Rooftop at The Hard Rock
Register here: https://luma.com/BookSignings_2025

Meet the authors behind two of the most talked-about new releases in blockchain, startups, and finance at Blockchain Futurist Conference Florida 2025. Join Amanda Wick (The Catalysts) and Annelise Osborne (From Hoodies to Suits), for an intimate book signing and conversation on innovation, leadership, and the future of finance. Don’t miss your chance to meet the authors and take home signed copies of their books.

Crypto in Your Pocket: Tangem Wallet Interactive Session

Wednesday, November 5
11:30 PM – 12:30 PM
DAER Rooftop at The Hard Rock
Register here: https://luma.com/Tangem_Workshop

Tangem invites you to discover how their card based hardware wallet makes owning and managing digital assets secure, simple, and fast. In this interactive session, you’ll learn how to set up a wallet in minutes, safeguard your crypto without seed phrases, and explore the future of user-friendly self custody.

Facilitated Networking with AWIC

Wednesday, November 5
1:30 PM – 2:30 PM
Entice Nightclub at The Hard Rock
Register here: https://luma.com/Networking_AWIC

Join the Association for Women in Crypto (“AWIC”) for a guided networking session presented by ETHWomen, an official segment of Blockchain Futurist Conference Florida 2025. Designed to foster meaningful connections among women and allies in Web3, this session features structured conversations and facilitated introductions to help participants share insights, build relationships, and explore opportunities across blockchain, crypto, and emerging technologies.

Web3 and Crypto Bootcamp for Beginners

Wednesday, November 5
9:30 PM – 11:30 PM
Entice Nightclub at The Hard Rock
Register here: https://luma.com/Crypto_Bootcamp_2025

New to Crypto? 🚀 Join this free, hands-on bootcamp designed for beginners ready to confidently step into the world of blockchain and Web3. Learn how to set up your first wallet, send and receive funds safely, protect yourself from scams, and understand the basics of Web3, NFTs, and DeFi. No prior experience is required, just bring your curiosity and get ready to start your Web3 journey in a fun, supportive environment.

AftHER HOURS by Fem T3ch & CreateHER Fest

Wednesday, November 6
3:00 PM – 6:00 PM
DAER Rooftop at The Hard Rock
Register here: https://luma.com/AFTHER_HOURS_2025

Join Fem T3ch and CreateHER Fest for a unique meetup designed to connect and empower women in Web3 and emerging technology. Part of ETHWomen, an official segment of the Blockchain Futurist Conference Florida 2025, this is a curated experience designed for impact, premium networking, and meaningful conversations.

Guitar Hotel Light Show

Wednesday, November 5-6
8:30 PM – 9:00 PM
DAER Rooftop at The Hard Rock
Register here: https://luma.com/GuitarLightShow

Experience the stunning Guitar Hotel Light Show at the iconic Hard Rock Guitar Hotel. This nightly display of lights, music, and special effects transforms the 450-foot guitar-shaped hotel into a must-see attraction. Enjoy it poolside with fellow crypto enthusiasts. Admission is free and open to the public. For the best view, visit the photo area at the southeast corner of the pool lagoon.

CryptoMondays Fort Lauderdale – Official Blockchain Futurist Conference Kickoff

Monday, November 3
6:00 – 9:00 PM
LauderAle Brewery
Register here: https://luma.com/11kd2sjd?tk=BQObyw

CryptoMondays isn’t just a meetup—it’s a global decentralized movement energizing Web3 and crypto communities through learning, networking, and inspiration.  Join them at LauderAle Brewery on Monday, November 3, 2025, as we welcome attendees, innovators, and the global Web3 community before the main event at the Hard Rock Guitar Hotel.

RWA 2.0: Building the Infrastructure of Trust

Tuesday, November 4
6:00 – 9:00 PM
W Fort Lauderdale
Register here: https://luma.com/11kd2sjd?tk=BQObyw

As tokenization accelerates, Real-World Assets (“RWAs”) are becoming the cornerstone of the next financial revolution. Join leaders from Trusted Smart Chain, The People’s Reserve, Kinesis Money, DPI Capital, Dfns, and T7X as we explore the evolution of RWA infrastructure — from custody and compliance to liquidity and secondary markets. This intimate fireside discussion brings together founders, fund managers, and technologists building the trust layer for on-chain finance.

SheFi Miami Presents: Blockchain Futurist Pre-Event Experience

Tuesday, November 4
7:30 – 10:00 PM
Painting with a Twist
Register here: https://luma.com/pjuarasw

Join SheFi Miami–Fort Lauderdale for an exclusive Blockchain Futurist Pre-Event Experience — a curated evening of creativity, connection, and inspiration. ​Hosted the night before the Blockchain Futurist Conference, this gathering brings together innovators, creators, investors, and visionaries shaping the future of blockchain, AI, and digital culture. ​Expect a high-level networking experience with a creative twist — blending art, conversation, and purpose in a relaxed, inspiring setting.

The Hard Rock Guitar Hotel and Casino

To top it off, attendees can look forward to exploring the many bars, restaurants, and lounges spread throughout the resort. From casual hangouts to upscale dining spots, every corner offers a chance to unwind, connect, and continue the conversations beyond the conference floor. The entire venue will be buzzing with Futurist Conference badges and endless opportunities to network, collaborate, and make lasting connections.

For tickets and info about Blockchain Futurist Conference: www.futuristconference.com
To register for all side events: https://luma.com/futurist_conference

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This article has been disseminated on behalf of Silvercorp Metals and may include a paid advertisement.

• Silvercorp Metals is a Canadian precious metals producer with a proven track record in China and plans to open new operations in South America.
• Shares have more than doubled in 2025 amid strengthening precious metals markets, yet the company continues to trade at levels that may not fully reflect its business fundamentals and growth prospects.
• Development of the El Domo copper-gold project in Ecuador is expected to boost revenues by 50% upon commissioning in late 2026.
• Silvercorp reported revenues of $81.3 million from silver, gold, lead, and zinc sales, during its most recent quarterly period, achieving more than $600 million in profits since 2006, returning more than $200 million of that to investors.

Precious metals such as gold and silver are regaining their shine despite contrary winds in the marketplace. Silver, particularly, has outperformed gold, climbing more than 68% this year (https://ibn.fm/ySJm9), -and recently surpassing its 2011 all-time high of $49.83, now trading above $50 (https://ibn.fm/wbBKj).

The prices have driven a rally in silver producers as market watchers bet on Federal Reserve rate cuts and a continued global de-dollarization trend (https://ibn.fm/ZI1xW).

Precious metals producer Silvercorp Metals (NYSE American/TSX: SVM) has benefited from the trend, more than doubling its share price this year. Despite this strong rally, the company continues to show value potential relative to peers on the strength of its asset base.

The company is well-positioned for a re-rate with:

• One of the highest silver exposures in the sector
• Strong cost management supporting margin expansion at higher prices
• Funded growth in Ecuador, including construction of the El Domo mine, expected to boost revenue by 50% and enhance diversification
• The potential for additional M&A supported by a strong balance sheet.

Two sell-side firms recently initiated coverage on Silvercorp, highlighting the company’s strong fundamentals and near-term growth potential.

The analyst at Cantor Fitzgerald (https://ibn.fm/h5Be1) counseled that “Investors stand to benefit from steep production growth, leverage to the silver price and multiple expansion on an improved risk profile as (Silvercorp’s) Ecuador operation comes online.”

Cormark Securities echoed the view, stating that “Silvercorp’s valuation (on NAV and cash flow) is at the bottom end of its silver producer peers despite its scale, long reserve life, and high margins. We believe most of this can be explained by its exposure to China, which we expect it to continue diversifying away from. Silvercorp has been successfully operating in China, and moving capital out of it, since 2006.”

Silvercorp has been successfully operating in China since 2006, with new focus recently on the potential of a mining operation a world away in Ecuador. The company has a copper-gold mine under construction there named El Domo, which has an anticipated 10-year life, and a scoping study underway for a separate gold deposit named Condor. El Domo construction is well underway with commissioning of the mine and process plant anticipated next year. Once operational, the project is expected to boost total company revenue by about 50% and strengthen geographic diversification.

In the meantime, Silvercorp’s flagship operation in China continues to drive revenues, with $81.3 million from silver, gold, lead and zinc sales reported during the most recent quarter, and generating $22.5 million in free cash flow (https://ibn.fm/oGtPI). The company’s profitable mines in China have enabled it to return more than $200 million to shareholders via dividends and share buybacks (https://ibn.fm/w5Q1e).

For more information, visit the company’s website at https://silvercorpmetals.com/.

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• The sheriff’s agency selected SuperCom’s PureSecurity(TM) platform for its advanced mobile features and high-precision tracking.
• The Utah win adds to recent U.S. contracts in Kentucky and Virginia, and international wins such as a $7 million project in Germany.
• SuperCom’s modular electronic monitoring (“EM”) technology supports programs for house arrest, domestic violence prevention, and inmate monitoring.
• Studies show EM programs can cut recidivism by up to 48%, improving rehabilitation outcomes and public safety.

SuperCom (NASDAQ: SPCB), a global provider of secured e-Government, IoT, and cybersecurity solutions, has strengthened its U.S. presence with a second electronic monitoring contract in Utah this year, continuing a run of wins across American sheriff’s departments and community supervision agencies. The company announced the new engagement on October 16, marking a direct contract with a second Utah sheriff’s agency that will adopt its PureSecurity(TM) Suite to replace an incumbent vendor (https://ibn.fm/WSQVa).

The decision to switch providers underscores growing confidence in SuperCom’s technology, which combines RFID and GPS tracking along with cloud-based software into a single modular monitoring system designed for public safety agencies managing probation, parole, or domestic violence prevention programs.

This second Utah win follows SuperCom’s initial entry into the state earlier this year. The company’s PureSecurity(TM) platform will now support two sheriff agencies in Utah, providing real-time tracking and integrated data analytics to streamline offender supervision.

“Winning another direct agency contract in Utah is further validation of our technology and the execution capabilities of our U.S. team,” said Ordan Trabelsi, President and CEO of SuperCom. “We are seeing growing demand from sheriff departments and community supervision agencies across the country that are actively seeking to replace outdated systems with modern solutions that deliver measurable results.”

Trabelsi added that similar momentum is visible nationwide, as agencies increasingly opt for scalable and data-driven alternatives to legacy systems. “Whether it’s multi-million-dollar national projects like our recent $7 million award in Germany or sheriff-level deployments in Utah, Kentucky, and Virginia, our mission remains the same: to deliver scalable, field-proven solutions that strengthen public safety and support program growth,” he said.

SuperCom’s PureSecurity(TM) Suite is built to meet diverse public safety needs, from house arrest and domestic violence prevention to inmate monitoring and probation management. The platform allows agencies to customize deployments using a suite of interoperable tools, including:

• PureMonitor(TM), a cloud-based software hub for real-time supervision.
• PureOne(TM), a one-piece GPS bracelet for continuous tracking indoors and outdoors.
• PureCom(TM), a radio frequency (“RF”) base station for house arrest programs.
• PureTag(TM), a compact RF bracelet compatible with other PureSecurity components.
• PureTrack(TM), a smartphone-based GPS tracking system, paired with the PureTag.
• PureShield(TM) (U.S.) and PureProtect(TM) (EU), mobile-based solution that safeguards victims of domestic violence through proximity alerts.
• PureBeacon(TM), an RF device for indoor surveillance in environments where GPS signals are limited.
• PureReader(TM), used for monitoring inmate movements within detention centers.

Each system can be scaled to meet specific agency requirements, enabling flexible adoption and interoperability.

SuperCom’s growing traction in Utah mirrors a broader trend in U.S. law enforcement technology procurement. Agencies across the country are moving away from legacy providers in favor of modern, integrated solutions that enable more effective resource allocation, data collection, and compliance management.

Beyond the U.S., the company’s $7 million national project in Germany, replacing a vendor that served the program for over two decades, highlights its competitive positioning internationally. Similar programs are active in Sweden, Romania, and other European countries, reflecting the company’s success in displacing long-standing incumbents.

With over 30 new contracts signed since mid-2024, SuperCom’s electronic monitoring business is expanding rapidly. The company’s modular technology, field-proven reliability, and flexible deployment model are helping law enforcement agencies modernize supervision systems while maintaining a focus on safety, compliance, and rehabilitation.

The adoption of electronic monitoring technologies such as SuperCom’s has been supported by a growing body of research highlighting their effectiveness in reducing reoffending rates. A 2013 study in Argentina found that electronic monitoring reduced one-year recidivism by up to 48% (Di Tella and Schargrodsky, 2013) (https://ibn.fm/8CI52). In Australia, research showed a 28% decrease in two-year recidivism (Williams and Weatherburn, 2020) (https://ibn.fm/SLV8H). In France, the likelihood of re-offending within five years dropped by around 10% (Henneguelle et al., 2016) (https://ibn.fm/X7m8W).

“With a growing customer base, a differentiated technology suite, and a disciplined execution strategy, SuperCom is helping reshape how public safety agencies operate—across the U.S. and around the world,” Trabelsi concluded.

For more information, visit the company’s website at www.SuperCom.com.

NOTE TO INVESTORS: The latest news and updates relating to SPCB are available in the company’s newsroom at http://ibn.fm/SPCB

• Sapu003 Phase 1 trial begins: Australian HREC approval validates Oncotelic’s proprietary 20nm nanoparticle technology for enhanced breast cancer drug delivery
• 20nm Deciparticle(TM) achieves full bioavailability: Intravenous delivery of Everolimus (Afinitor(R)) maximizes tumor targeting and efficacy compared to 10% absorption with oral formulations
• Rapid IND platform accelerates pipeline: Strategic partnership with Medicilon supports up to 20 IND projects, shortening development timelines and enabling multiple Deciparticle(TM) drug candidates to reach clinical testing quickly

Oncotelic Therapeutics Inc. (OTCQB: OTLC) is advancing precision nanomedicine with its proprietary Deciparticle(TM) platform, beginning human trials for Sapu003, a 20nm nanoparticle formulation of Everolimus (Afinitor(R)). This scientific briefing explores why particle size is critical to drug efficacy, how Oncotelic’s technology enhances tumor targeting, and how its rapid IND platform accelerates clinical development across multiple assets.

Particle Size: The Key to Targeted Drug Delivery

Delivering anticancer drugs effectively remains a central challenge in oncology. Conventional chemotherapy exposes healthy tissues to cytotoxic agents, producing severe side effects, while oral targeted therapies often fail to reach tumors at therapeutic concentrations. Nanomedicine offers a solution, but particle size determines whether a drug reaches its intended site.

Nanoparticles in the range of 10–100 nanometers exploit the enhanced permeability and retention (“EPR”) effect, a phenomenon where leaky tumor vasculature allows small particles to penetrate and accumulate in tumor tissue while largely sparing healthy organs. However, not all nanoparticles in this size range perform equally. Particles smaller than 10nm are rapidly filtered by the kidneys, limiting exposure, whereas particles above 100nm trigger immune clearance before reaching tumors.

Recent research highlights ~20nm as an optimal size for balancing systemic circulation, tissue penetration, and tumor accumulation. These particles are small enough to traverse vascular pores but large enough to avoid premature renal clearance, allowing sustained drug exposure within tumors for enhanced therapeutic effect.

Translating Nanoparticle Precision into Clinical Potential

Oncotelic’s first Deciparticle(TM) candidate, Sapu003, reformulates Everolimus (Afinitor(R)), an mTOR inhibitor approved for breast cancer and other tumors, into 20nm nanoparticles for intravenous delivery. Oral Everolimus (Afinitor(R)) faces a critical limitation: only ~10% bioavailability, as most of the drug is lost in the digestive system and causes gastric toxicity. By contrast, Sapu003 delivers 100% of the drug directly into circulation, maximizing tumor exposure.

To that point, Sapu003 nanoparticle enables the drug to exit blood vessels through their large pores and reach tumor tissue efficiently. Larger particles would require breakdown before extravasation, reducing both efficacy and safety.

Preclinical studies support this principle. Nanomedicines ≤50nm demonstrate superior tissue penetration, enhanced tumor inhibition, and reduced systemic toxicity compared to larger formulations. By hitting the 20nm target, Sapu003 achieves a combination of precision targeting, high bioavailability, and safety, representing a meaningful advance over prior nanomedicine approaches such as Abraxane(R) (130nm) and Cynviloq(TM) (80nm).

Manufacturing at Scale: Achieving 20nm Consistency

Engineering nanoparticles at precise dimensions is technically challenging. Sapu Nano, Oncotelic’s joint venture, operates the world’s first GMP-certified facility designed specifically for Deciparticle(TM) production. The facility allows consistent 20nm particle generation at clinical scale, supporting both current trials and future pipeline expansion.

This capability distinguishes Oncotelic from earlier nanomedicine efforts, where size variability limited reproducibility and clinical translation. By controlling particle engineering at scale, Oncotelic ensures that each dose behaves predictably in vivo, a critical factor for regulatory approval and clinical efficacy.

Rapid IND Platform: Accelerating Multiple Drug Candidates

Oncotelic is leveraging its Deciparticle(TM) technology as a platform capable of reformulating multiple drugs with known safety profiles. Its strategic February 2025 partnership with Shanghai Medicilon Inc. supports up to 20 IND projects, providing a rapid IND pathway that accelerates clinical readiness.

Medicilon brings extensive regulatory experience with the FDA, EMEA, and NMPA, including a clean inspection history with no FDA 483 citations. This reduces risk and shortens timelines for Oncotelic’s clinical programs. Under this partnership, drug candidates can move from proof-of-concept to preclinical to first-in-human studies more efficiently than typical development cycles.

The 505(b)(2) regulatory pathway is particularly well-suited to Deciparticle(TM) reformulations. Because the underlying drugs are already FDA-approved, Oncotelic can leverage existing safety and efficacy data, potentially reducing clinical development time from 10–15 years to 5–10 years, while lowering cost and risk. This strategy enables rapid testing of multiple assets, expanding Oncotelic’s pipeline and positioning the company as a platform innovator in nanomedicine.

Clinical Trial Design and Market Implications

Sapu003’s Phase 1 trial (ACTRN12625001083482) is now enrolling at Australian oncology centers through partnerships with SOCRU and Ingenū, focusing on adults with advanced HR+/HER2- breast cancer or other mTOR-sensitive tumors who have exhausted standard therapies.

Breast cancer represents a global market exceeding $30 billion, forecasted to reach over $40 billion by 2030. Oral Everolimus (Afinitor(R)) has historically captured a portion of this market, generating over $1.5 billion in 2020. An injectable formulation with superior bioavailability could reclaim share while expanding access to patients unable to tolerate oral therapy, as full drug absorption through intravenous delivery has the potential to achieve meaningful tumor shrinkage where oral formulations have been limited.

From Particle Engineering to Patient Outcomes

The global nanomedicine market was valued at ~$215 billion in 2023 and is projected to exceed $500 billion by 2032, largely driven by oncology applications and the recognition that particle size optimization can transform outcomes. Oncotelic’s Deciparticle(TM) platform aligns with this trend, offering a scalable, reproducible, and clinically validated approach to nanoparticle drug delivery.

With Sapu003 entering human trials, GMP-scale manufacturing of 20nm particles, and rapid IND support for up to 20 drug candidates, Oncotelic has built a comprehensive ecosystem for translating nanomedicine innovation into measurable clinical impact. For investors and stakeholders interested in next-generation cancer therapeutics, OTLC exemplifies how precision particle engineering and streamlined regulatory pathways can combine to shorten development cycles and enhance patient outcomes.

For more information, visit the company’s website at www.Oncotelic.com.

NOTE TO INVESTORS: The latest news and updates relating to OTLC are available in the company’s newsroom at ibn.fm/OTLC

• 100% owned Hasbrouck Gold Project offers zero construction risk until gold price justifies development, providing pure leverage to rising prices without execution overhang
• 110% IRR at $2,600 gold demonstrates explosive economics as spot prices top $4,000, while $1M annual burn rate and $2M cash preserve optionality for approximately 2 years without dilution
• Strategic positioning attracts gold-focused funds and potential M&A interest as one of few shovel-ready gold companies with no legacy liabilities in world-class Nevada jurisdiction

When Patience Becomes Strategy in a Bull Market

Gold’s recent surge past $4,000 per ounce has reignited investor interest in precious metals equities, but not all gold stocks are created equal. While producers benefit from higher revenues, they also face rising input costs, operational risks, and capital allocation decisions that can destroy value. These companies offer potential but carry geological, permitting, and financing uncertainties that make them unsuitable for risk-averse investors. Between these extremes lies a rare category: fully permitted, construction-ready projects held by disciplined management teams willing to wait for optimal market conditions before pulling the trigger.

West Vault Mining (TSX.V: WVM) (OTCQX: WVMDF) occupies precisely this strategic middle ground. The company owns 100% of the Hasbrouck Gold Project in Nevada’s Walker Lane, a 753,000-ounce proven and probable reserve with robust economics demonstrated in its January 2023 Pre-feasibility Study. Unlike typical companies, racing toward construction regardless of market conditions, West Vault’s philosophy centers on “disciplined patience drives value creation.”

This approach delivers a compelling proposition: shareholders gain full exposure to gold price appreciation without taking on construction, production, or operational risks until economics justify development.

The numbers validate this strategy. At a conservative $1,790/oz gold assumption, Hasbrouck demonstrates a 51% after-tax IRR and $206 million NPV. Although, the real leverage emerges at current market prices. At $2,600/oz gold – well below today’s spot price – the project’s IRR explodes to 110% with NPV reaching $503 million. This exponential sensitivity to gold prices creates asymmetric upside: if gold continues rising, Hasbrouck’s value multiplies; if prices decline, West Vault simply waits, burning minimal cash while preserving shareholder equity.

Market Positioning Creates Multiple Catalysts

West Vault’s has several catalysts that could drive near-term value recognition:

• Higher Gold Levels Drive Value Accretion: With gold hitting record highs and J.P. Morgan Research forecasting prices to average $3,675/oz by Q4 2025, Hasbrouck’s economics continue improving. Every $100 increase in gold prices adds meaningful NPV while further validating the company’s patient capital approach.
• Exploration Upside Near Permitted Zones: The project encompasses 11,400 acres with multiple exploration targets including extensions to known mineralization, open high-grade corridors, and potential high-grade structures at both the Three Hills and Hasbrouck pits. The Hill of Gold area represents additional upside opportunity. Importantly, exploration can occur without triggering construction commitments, allowing West Vault to potentially expand resources while maintaining its wait-and-see posture on development.
• Strategic Partnership or Financing Alternatives: As one of few fully permitted, construction-ready junior developers in Nevada, West Vault attracts attention from larger producers seeking to acquire permitted ounces in safe jurisdictions. The company’s clean capital structure (no debt, minimal burn rate, no legacy liabilities or third-party encumbrances) makes it an attractive partner or acquisition target. Strategic alternatives could include joint ventures, royalty/streaming deals, or outright acquisition; each potentially crystallizing value for shareholders without requiring West Vault to assume construction risk.
• Potential M&A Activity: The mining sector has seen increased consolidation as major producers face declining reserve bases and seek quality assets in tier-one jurisdictions. Nevada projects command premium valuations due to mining-friendly regulations, established infrastructure, and minimal political risk. West Vault’s fully permitted status eliminates a major uncertainty that plagues most junior developers, positioning Hasbrouck as a turnkey opportunity for acquirers.
• Strong Visibility with Gold-Focused Funds: West Vault’s 72% institutional ownership and 48% insider ownership demonstrate alignment with long-term shareholders. The company’s transparent, patient strategy resonates with sophisticated investors who understand that premature development can destroy value. As gold prices strengthen and market attention shifts toward quality development assets, West Vault’s shareholder base provides natural momentum for re-rating.

Nevada Advantage Reinforces Low-Risk Profile

Nevada produces about 70% of U.S. gold output, supported by world-class geology, modern infrastructure, and supportive regulatory frameworks. Hasbrouck benefits from this ecosystem: grid power located one mile away, on-site water rights, easy highway access, and proximity to Tonopah’s established mining services infrastructure. The project’s simple run-of-mine heap leach process eliminates need for complex processing plants, while contractor mining further reduces capital requirements.

These advantages translate into rapid development timelines once a construction decision is made – approximately 12 months to first gold pour from Three Hills, with the Hasbrouck pit following roughly 18 months later. The two-phase approach allows Phase 1 cash flow to fund Phase 2 development, minimizing external financing requirements.

Capital Efficiency Protects Shareholder Value

With $2 million cash, zero debt, and a minimal burn rate of approximately $1 million annually, West Vault can maintain its current posture for roughly two years without additional dilution. This runway extends even further if gold prices continue rising, as stronger economics reduce pressure for premature capital raises. Management’s commitment to “minimizing dilution and preserving NAV/share” aligns perfectly with shareholder interests.

The 58 million shares outstanding and C$123 million market capitalization create significant re-rating potential as the market recognizes Hasbrouck’s value in the context of $4,000+ gold. The company’s current valuation implies minimal value for exploration upside, optionality, or the strategic premium Nevada assets command in M&A transactions.

West Vault Mining exemplifies how disciplined capital allocation can create asymmetric risk-reward profiles in resource investing. By refusing to chase construction for its own sake, management has preserved optionality while maintaining full leverage to gold price appreciation. As spot prices rise and catalysts multiply, from continued exploration success to strategic partnership opportunities, West Vault stands positioned for potential re-rating that could unlock substantial value for patient shareholders willing to let the gold bull market do the heavy lifting.

For more information, visit the company’s website at www.WestVaultMining.com.

NOTE TO INVESTORS: The latest news and updates relating to WVMDF are available in the company’s newsroom at ibn.fm/WVMDF

This article has been disseminated on behalf of Trilogy Metals and may include a paid advertisement.

• TMQ recently secured a $35.6 million strategic investment from the American Department of War to speed up development at the Upper Kobuk Mineral Projects (“UKMP”) in Alaska
• President Donald Trump issued a decision to grant permits for the Ambler Access Project, making the development of domestic critical mineral assets possible
• These strategic developments underscore Trilogy’s pivotal role in America’s minerals strategy, supporting the country’s national security and energy objectives
• These updates help advance Trilogy’s mission to strategically develop Alaska’s world-class mineral district, in addition to protecting the environment and empowering local communities

Trilogy Metals (NYSE American: TMQ) (TSX: TMQ) is making significant progress in its efforts to boost America’s local supply chain for essential minerals. The company recently announced two major milestones: President Donald Trump’s restoration of permits for the Ambler Access Project, a 211-mile industrial-use-only road linking Alaska’s Dalton Highway to the Ambler Mining District, and a crucial $35.6 million investment from the U.S. Department of War.

The U.S. Department of War’s investment, through the Office of the Undersecretary of Defense for Acquisition and Sustainment, will grant the government a 10% interest in Trilogy Metals. The funding will help accelerate exploration and development efforts at the Upper Kobuk Mineral Projects. This strategic partnership underscores the critical role of American copper, zinc, cobalt, and lead in driving technology, energy systems, and advanced manufacturing (ibn.fm/3weGF).

“This proposed partnership with the U.S. Government represents a significant milestone for Trilogy Metals and for the development of a secure, domestic supply of critical minerals for America in Alaska,” according to Trilogy Metals’ President and CEO Tony Giardini. “We look forward to working with our partners at South32, federal and state agencies, and Alaska Native communities to advance this world-class district responsibly and collaboratively.”

The President’s decision under Section 1106 of the Alaska National Interest Lands Conservation Act (“ANILCA”) restores the permits needed for the Ambler Access Project, which were terminated by the previous administration. The Ambler Road is expected to enable strategic access to the Arctic and Bornite deposits while preserving the local ecosystems and wildlife corridors (ibn.fm/JXTCF).

The road is expected to create lasting economic opportunities for Alaska Native communities, through contracting, employment, and infrastructural benefits while adhering to environmental protection rules.

For America, these updates not only signify progress being made in Alaska – they also align with the national mineral policy, ensuring secure domestic sources of metals crucial to defense and clean energy. Trilogy has a clear pathway towards developing the Ambler Mining District into a leading North American copper hub.

With the strategic support from the Alaska Industrial Development and Export Authority, the State of Alaska, and the federal government, Trilogy is well positioned to transition from exploration to production. Environmental work, engineering updates, and engagement with the community are the next steps in the next few months.

For more information, visit www.TrilogyMetals.com.

NOTE TO INVESTORS: The latest news and updates relating to TMQ are available in the company’s newsroom at ibn.fm/TMQ

• The renewable energy company has signed a lease agreement for a 6.9 MW DC ground-mounted solar project in New York’s Capital District.
• The project, known as NY-Crawford Rd, is expected to qualify for incentives under the NYSERDA NY-Sun Program, and, once operational, it will supply enough clean energy to power approximately 800 homes.
• The company has already begun the interconnection application and preliminary screening analysis, marking the first stage of development.
• PowerBank brings experience from over 100 MW of completed projects and a development pipeline exceeding 1 GW, contributing to New York’s Climate Leadership and Community Protection Act goal of 6 GW of solar capacity by 2025.

Disseminated on behalf of PowerBank Corporation

PowerBank (NASDAQ: SUUN) (Cboe CA: SUNN) (FSE: 103), a premier developer and owner of renewable and clean energy projects, specializing in distributed and community solar initiatives throughout Canada and the U.S., has announced progress on a new 6.9-megawatt (“MW”) direct current (“DC”) solar project in New York’s Capital District. The initiative, called the NY-Crawford Rd Project, represents another step in the company’s ongoing strategy to expand its footprint in distributed and community solar infrastructure across North America (https://ibn.fm/lKPjF).

According to PowerBank’s announcement, the lease agreement for the project site has been finalized. The company has initiated the interconnection process, which includes a preliminary screening analysis to assess grid capacity and technical feasibility. Once approval is granted, PowerBank plans to move forward with permitting and project financing before construction begins.

The NY-Crawford Rd Project will operate as a community solar development, a model that enables residents, businesses, and renters to access renewable energy without installing panels on their own properties. Under this model, subscribers receive credits on their monthly utility bills based on the electricity produced by the shared solar array. The system feeds clean energy directly into the local grid, allowing participants to offset their consumption with renewable power and lower their overall electricity costs.

For the region, the project will contribute enough renewable energy to power around 800 homes, furthering the state’s broader decarbonization and energy resilience goals.

The project aligns with the New York State Energy Research and Development Authority (“NYSERDA”) NY-Sun Program, which provides financial incentives and technical support for solar developers. The initiative is a cornerstone of New York’s Climate Leadership and Community Protection Act (“CLCPA”), which mandates at least 6 GW of distributed solar capacity by 2025 and 70% renewable electricity by 2030.

With nearly one-third of the U.S.’s 6.2 GW of installed community solar capacity located in New York, the state remains a national leader in the sector. PowerBank’s project adds incremental progress toward those targets while broadening access to renewable power in the Capital District region.

PowerBank Corporation has more than 100 MW of completed renewable energy projects and a development pipeline exceeding 1 GW. Its business model combines project origination, financing, and long-term asset management, with customers spanning utilities, municipalities, and commercial entities.

By developing projects like NY-Crawford Rd, PowerBank aims to diversify its revenue streams and strengthen its portfolio of income-generating clean energy assets.

Following the completion of interconnection and permitting, PowerBank intends to secure financing for the construction phase. The company has not yet announced a construction start date but indicated that the project will proceed upon approval of the necessary regulatory steps.

For more information, visit the company’s website at https://PowerBankCorp.com.

This report contains forward looking information. Please refer to the press release entitled “PowerBank Announces New 6.9 MW Solar Project in the Capital District, New York” and dated October 7, 2025, for additional details on the information, risks and assumptions.

NOTE TO INVESTORS: The latest news and updates relating to SUUN are available in the company’s newsroom at https://ibn.fm/SUUN