• The CDC estimates that by 2060, over 14 million Americans may be diagnosed with Alzheimer’s, up from the current 6.5 million
• In a surprising study, presented at the 2022 Alzheimer’s Association International Conference, it was noted that this rise could be largely attributed to people’s intake of ultra-processed foods, which was linked to a higher risk of dementia
• Of the 10,000 participants who took part in the study, it was noted that those who ate the most ultra-processed foods had a 28% faster rate of global cognitive decline, and a 25% faster rate of executive function decline compared to those who ate the least amount of overly processed food
• MetAlert is pushing for lifestyle and dietary changes while helping to sensitize people on the risks associated with the consumption of ultra-processed foods
• Even as it continues to design, develop, manufacture, distribute and sell products and services in the GPS/BLE wearable technology space, MetAlert is strongly pushing for healthier dietary and lifestyle alternatives guaranteed to reduce the risk of cognitive decline

MetAlert (OTC: MLRT), a developer of personal protective medical equipment and supplies and a pioneer in wearable GPS, human, and asset tracking systems, has, since its inception, shown a commitment to those afflicted with Alzheimer’s, dementia, and autism (“ADA”). This commitment has gone beyond developing location-sensitive health monitoring devices, particularly with the Centers for Disease Control (“CDC”) estimating that by 2060 over 14 million Americans may be diagnosed with Alzheimer’s, up from the current 6.5 million (https://ibn.fm/XYIKQ). MetAlert is pushing for lifestyle and dietary changes that have proven to lower the risk of cognitive decline. In a recent study presented at the 2022 Alzheimer’s Association International Conference, researchers noted that, of the 10,000 study participants, those who consumed more than 20% of their calories from ultra-processed foods had a higher risk of dementia. It further noted that those who ate the most ultra-processed foods had a 28% faster rate of global cognitive decline and a 25% faster rate of executive function decline than those who ate the least amount of overly processed food (https://ibn.fm/AzAPS). In a separate study published by the Harvard Medical School, it was noted that there is a clear correlation between developing dementia and earlier intake of ultra-processed foods. Researchers cited that switching out an estimated 10% of such foods with an equivalent proportion of unprocessed or minimally processed foods, such as fruits and vegetables, could lower dementia risk by as much as 19%. This study followed the dietary habits of over 72,000 people aged 55 and older over an average of 10 years (https://ibn.fm/VhqyW). “58% of the calories consumed by United States citizens, 56.8% of the calories consumed by British citizens, and 48% of the calories consumed by Canadians come from ultra-processed foods,” noted Dr. Claudia Suemoto, an assistant professor in the division of geriatrics at the University of São Paulo Medical School. With a small order of fries and a regular cheeseburger from McDonald’s containing 530 calories while offering a simple, convenient meal while at it, it is easy to see why ultra-processed foods contribute a huge chunk of people’s daily caloric intake. However, MetAlert is helping to sensitize people on the issue, encouraging them to substitute such foods with better quality alternatives. One way to do so is to prepare food from scratch, a sure way of protecting one’s heart and guarding their brain against dementia and Alzheimer’s disease. This move will benefit not only one’s cognition but also lower one’s risk of obesity, diabetes, cancer, heart and circulation problems, as well as the risk of a shorter lifespan. Moreover, given their high sugar, salt, and fat concentration, these foods promote inflammation throughout the body, leaving one pre-disposed to a growing list of other medical conditions. Even as MetAlert continues to design, develop, manufacture, distribute and sell products and services in the GPS/BLE wearable technology and health data collection and monitoring space, it emphasizes that prevention is better than cure. As such, it pushes people to adopt healthier dietary and lifestyle alternatives that reduce cognitive decline risk. For more information, visit the company’s website at www.MetAlert.com. NOTE TO INVESTORS: The latest news and updates relating to MLRT are available in the company’s newsroom at https://ibn.fm/MLRT

• Methane, a potent greenhouse gas, accounts for over 30% of global warming dating back to pre-industrial times
• Despite its connotations as a relatively clean fossil fuel, natural gas is 70-90% made up of methane
• A key source of greenhouse emissions in recent year has been the leakage of methane from natural gas fracking operations
• Renewable Natural Gas presents a carbon neutral alternative to natural gas, with production increasing by over 20% YoY in both, the United States and Canada over the past year
• EverGen Infrastructure Corp. has been at the forefront of the development of North America’s RNG production capacity; by early 2023, the company targets over 230 gigajoules per day of RNG production capacity

Methane, a potent greenhouse gas and major contributor to global warming, has historically borne an association with cow burps and wetlands (https://ibn.fm/qCrGW). Over 80 times more potent than carbon dioxide, methane has been found to account for approximately 30 percent of global warming since pre-industrial times and is currently proliferating faster than at any time since record keeping first began in the 1980s (https://ibn.fm/ks84p). In comparison, natural gas has been hailed as the potential ‘bridge’ fuel towards a greener future, with consumers pointing towards the relatively lower carbon emissions generated through the use of natural gas relative to the likes of crude oil and thermal coal. Nonetheless, and despite its greener connotations and perception as a largely benign fossil fuel, natural gas is composed of 70-90 percent methane (https://ibn.fm/zUc8X), an oft forgotten statistic by natural gas advocates. Over the past decade, nearly two-thirds of all new gas production globally has emerged from the United States and Canada, a result of new natural gas fracking technology. A complex process entailing the injection of highly pressurized water, chemicals, and sand to create and prop open fissures for gas to flow, the United States is currently on track to produce upwards of 100 billion cubic feet of natural gas per day 2022 – much of it, a direct result of fracking technology. To put that figure into perspective, the United States accounted for nearly 24 percent of the globe’s total production of natural gas last year, over a third larger than that of the then second-largest producer, Russia. However, if only one percent of that natural gas production were to escape into the atmosphere during the fracking process, the relative advantages of burning natural gas over ‘dirtier’ fossil fuels is brought into question. As of 2021, the average ‘leakage rate’ of gas amongst U.S. natural gas producers languished at well over 2 percent (https://ibn.fm/9bP4F). A study carried out by NASA’s Jet Propulsion Laboratory in 2015 found that methane levels were unchanged for years, but increased sharply after 2006, growing by 25 million tons a year. Using satellites, NASA were able to conclude that fossil fuel production – in particular, natural gas, was responsible for between 12 and 19 million tons of this additional methane. “Isotopic analysis of gas samples [to track methane leakages] at wellheads across a number of fracking operations could easily prove or disprove [NASA’s] hypothesis,” remarked Anthony Ingraffea, a Professor of Engineering at Cornell University. “If [NASA] is right then we know shale gas operations are making global warming worse, and upending efforts to stay well below 2C.” British-Columbia based natural gas operator, EverGen Infrastructure (TSX.V: EVGN) (OTCQX: EVGIF) has been at the forefront of renewable natural gas production in North America, a process which has looked to harness methane as a key input with the eventual goal of manufacturing a ‘cleaner’ alternative to conventional fossil fuels. Unlike regular natural gas, RNG is not obtained from fossil resources; rather, it constitutes a carbon-neutral or even, carbon-negative fuel. Nevertheless, and despite its potential to contribute towards global carbon neutrality goals, RNG production has historically been limited given its relatively high cost and limited availability. However, that paradigm might now be changing. In 2021, RNG production within the United States was equivalent to 660 million gallons gasoline equivalents (“GGE”), an increase of over 20 percent relative to the previous year. While that is a lot of RNG, it remains just a fraction – about 3 percent – of the total natural gas consumption within the U.S. In Canada, the pace of growth has been even faster. The Canadian Biogas Association recently revealed that the production of biogas and renewable natural gas had the potential to halve the nation’s methane emissions by as much as half as of 2030. The movement has gained further impetus with various Canadian provinces introducing mandates to boost RNG use in recent years; in 2019, Quebec mandated that its gas grid would blend a minimum of 1-percent RNG into its feedstock mix, a figure set to rise to as much as 10 percent by 2030. EverGen Infrastructure has sought to capitalize on the move towards increased RNG production, with a publicly stated goal to own over 20 facilities across the country within five years. By early 2023 and following the conclusion of ongoing works at their Alberta-based GrowTEC operation, EverGen anticipates its production capacity to amount to upwards of 230 gigajoules per day of renewable natural gas – the equivalent of powering 100 British Columbia homes for a month. “We are a renewable natural gas energy company. We’re a developer, owner and operator of projects that take organic waste and convert that organic waste into renewable energy in the form of renewable natural gas (‘RNG’),” stated Chase Edgelow, Co-Founder and CEO of EverGen Infrastructure Cop. “If you look back at the benefits of bringing in other sources of energy 20 years ago, there wasn’t one silver bullet for the electrical grid to be as renewable as it is today, with wind, solar and hydro. I think renewable natural gas can hold its own, and at the same time solve a massive waste problem and emissions problem from waste,” he concluded. For more information, visit the company’s website at www.EverGenInfra.com. NOTE TO INVESTORS: The latest news and updates relating to EVGIF are available in the company’s newsroom at https://ibn.fm/EVGIF

• With over 500 million ransomware attacks in 1H2021, corporations have been increasingly looking for ways to safeguard their internal IT systems
• The need for data protection has been further heightened by increased regulatory scrutiny from foreign and domestic governmental agencies
• In the U.S., the recently passed Federal ADPPA privacy law will coincide with California’s Consumer Privacy Act, with the latter set to come into effect on January 1, 2023
• With a broad toolkit focused on data security and management, Data443 have sought to capitalize on the expanding global need for data protection services

Towards the beginning of May 2021, U.S. fuel prices started to unexpectedly spike. The Colonial Pipeline company, operator of a systemically crucial 5,500 mile long pipeline engaged in transporting fuel from the Gulf Coast to the New York metro area was shut down, suspending the flow of over 100 million gallons of fuel every day between Texas and New York (https://ibn.fm/YoGfq). In ensuing days, news would break that DarkSide, an emerging hacking consortium had held the company’s IT systems hostage – freezing its data and threatening to leak sensitive corporate information online. Colonial Pipeline would go on to pay a ransom of $2.3 million or 63.7 bitcoin at the time. Whilst dramatic in nature, the Colonial Pipeline ransomware attack was just one of nearly 500 million ransomware attacks taking place in the first half of 2021, a clear illustration of the need for corporations to engage in more robust cyber security efforts going forward. Focusing in on data security and a privacy-forward methodology, Data443 Risk Mitigation (OTC: ATDS) has emerged as a key player within the cyber security arena, strategically positioned to benefit from increased demand for data protection with its portfolio of software solutions, allowing for a unified approach to data governance and security. In January 2022, Data443 completed the acquisition of certain assets from Centurion Technologies, namely its ransomware protection and device recovery technologies, along with ancillary assets. Not only did the deal provide Data443 with the key technical prowess to comply with recently established requirements from the Cybersecurity & Infrastructure Security Agency (“CISA”), but this also enabled Data443 to build on an established franchise with over 3 million licenses deployed worldwide (https://ibn.fm/EvRvV). Jason Remillard, Data443’s Founder and Chief Executive Officer, commented, “This acquisition represents a major milestone for Data443.  Centurion’s ransomware recovery product has long been a differentiator since we first licensed it in 2021 for our product line. Investments in best-practice security programs, platforms, and frameworks have become a business necessity.” In addition to its ransomware recovery and data protection services, Data443’s extensive product suite has provided the company with the ability to deliver corporate solutions designed to securely manage data and data privacy needs on-premises, in the cloud and in hybrid environments. In recent months, data protection has been at the forefront of the global technological agenda, most recently due to the roughly $275 million fine meted out on Facebook parent, Meta by Ireland’s Data Protection Commission; the agency based the fine on Meta’s alleged negligence during a 2019 security hack which would ultimately lead to the personal information of over 533 million Facebook users leaked online. (https://ibn.fm/i9MwX). “With more countries introducing modern privacy laws in the same vein as the General Data Protection Regulation (‘GDPR’), the world has reached a threshold where the European baseline for handling personal information is now the de facto global standard,” explained Nader Henein, research vice president at Gartner. By 2023, 65% of the world’s population is set to have its personal data covered under modern privacy regulations, up from a mere 10% in 2020. The strong momentum underpinning the expansion of global data privacy laws has made it imperative for businesses to incorporate the demands of a rapidly evolving privacy landscape into their business’s data strategy. A failure from a business’s security and risk management department to adapt their personal data handling practices could increasingly expose the business to loss through fines or reputational damages, as highlighted by Meta’s recent travails. That requirement has been further heightened as a result of a spate of new consumer privacy regulations coming into effect. The recently passed Federal American Data Privacy and Protection Act (“ADPPA”), a new privacy law promising Americans many of the same consumer privacy rights as the European Union’s General Data Protection Regulation (“GDPR”) will make the protection of online consumer data privacy a nationwide requirement. Meanwhile and on a state level, the California Consumer Privacy Act (“CCPA”) will become fully operational as of January 1, 2023, with the regulations affording consumers the right to know about the personal information a business collects about them as well as how it is used and shared (https://ibn.fm/5iscH). Data443’s multitude of offerings – an all-encompassing toolset including data archiving, file sharing, access control, sensitive content management and global privacy management, has seen the company pick up an impressive slate of clients in recent months. These include a five-and-a-half-year contract with a “Fortune 500 Fintech Member,” a multi-year contract with a “leading financial services organization in Puerto Rico,” a multi-year contract with a “major US energy provider with over 30,000 employees,” and, only a few weeks ago, a $350,000 contract addition to an existing agreement with “a leading global investment bank headquartered in New York City with over $2 trillion in assets” (https://ibn.fm/VTTMQ). Remillard remarked on the company’s prospects going forward, “We continue to expand the adoption of our product sets in some of the world’s largest organizations, supporting business-critical data in flight and at rest, in the cloud or on-premises. I am confident that Data443 is well positioned to make the most of the substantial market opportunity before us, continuing our mission: To organize the world’s information by identifying and protecting all sensitive data regardless of location, platform, or format,” he concluded. For more information, visit the company’s website at www.Data443.com NOTE TO INVESTORS: The latest news and updates relating to ATDS are available in the company’s newsroom at https://ibn.fm/ATDS

• Hillcrest Energy began 2022 with proof-of-concept of its innovative traction inverter technology that overcomes shortfalls in today’s tech and improves EV motor efficiency
• The company ended the year with its first 800-volt 250-kilowatt commercial prototype that has attracted the attention of leading EV makers and Tier 1 automotive suppliers
• Hillcrest announced two co-development partners and is now working with them both to integrate the ZVS traction inverter into their specific commercial applications

As the new year arrives, it is a commonplace for companies and investors to reflect upon the last 12 months and hypothesize about where the next year will lead. In the EV space, 2022 will likely be remembered as the start of a steep adoption trajectory as more makes and models hit the roads. In that lane, the year was full of important milestones for Hillcrest Energy Technologies (CSE: HEAT) (OTCQB: HLRTF), a developer of high-performance power conversion technologies and digital control systems for next-generation powertrains and grid-connected renewable energy systems. In the words of Hillcrest CEO Don Currie, “the company met or exceeded every milestone we set out to achieve.” Those are confident words from a company that is drawing industry attention for its ZVS inverter technology. Power inverter technology is an unsung hero in Evs that converts high voltage direct current (“DC”) power stored in batteries to the alternating current (“AC”) needed for EV motors. That’s the simple way of putting it. In depth, power inverters convert batteries’ DC electricity into sinusoidal, three-phase, variable frequency AC power to move a car when the accelerator is pushed and subsequently capturing energy released through regenerative braking, converting it into a single DC output to charge the batteries, which helps extend travel range. This complex engineering is being perfected as the industry matures and Hillcrest sits as at the forefront ushering in next generation inverter tech. During 2022, Hillcrest published two technical white papers validating the value of its ZVS inverter technology. The publications highlighted demonstrations of the inverter achieving efficiency exceeding 99.4% at 60 hertz (“Hz”), improvements in motor efficiency of up to 13%, and the ability to reduce the size and weight of DC-link capacitors by as much as 50%. The technology behind the inverter eliminates switching losses and takes advantage of higher switching frequencies at higher voltage than its hard-switched silicon carbide competitors, offering improved motor efficiency, performance, and reliability. These improvements were instrumental in Hillcrest garnering attention of potential customers much earlier in development than anticipated. Before it had completed its first 800-volt 250-kilowatt commercial prototype in December, Hillcrest had already inked two co-development partnerships. Hillcrest isn’t at liberty to disclose everyone that the company is speaking and partnering with, although it has announced two co-development agreements so far. The first is with Hercules Electric Mobility and the second agreement is with a global Tier 1 automotive supplier. Both entities are now collaborating with Hillcrest to integrate the ZVS traction inverter into each partner’s specific commercial application. As it establishes its footprint in the green energy markets, the one-time fossil fuel play has ceased operations at its oil and gas asset, aside from activities required to successfully reclaim the property. Hillcrest is now 100% a clean energy company. To meet its goals, Hillcrest strengthened its leadership team in 2022, hiring firmware engineers with expertise in electric vehicles and grid-tied applications. “We’ve assembled an incredible team with deep understanding and expertise, from technology development to the commercialization and implementation stages,” said Hillcrest CTO Ari Berger in a statement. The company also onboarded David Farrell as Board Chairman and named Michael Moskowitz to the Board and Chairman of the Board’s Executive Committee. “We entered the year with a proof of concept for our core technology, the Hillcrest ZVS inverter technology, and progressed through design, commissioning and finally completion of our first customer-centered product,” added Currie. “Our technical team has delivered at every level and excitement is building around even bigger expectations in 2023.” For more information, visit the company’s website at www.HillcrestEnergy.tech. NOTE TO INVESTORS: The latest news and updates relating to HLRTF are available in the company’s newsroom at https://ibn.fm/HLRTF

• Correlate, a distributed energy solutions company, sees continued opportunities from rising government support for clean renewable energy
• Governmental push for green energy alternatives has grown over the past few years, evidenced by its support for multiple climate mitigation goals, such as achieving 100% wcarbon pollution-frewe electricity by 2035 and an NDC of 50-52% reductions below 2005, covering all sectors and all gases by 2030
• Achieving these goals calls for maximizing energy efficiency for nearly everything – from buildings to vehicles, with a mix of mandates and incentives
• New York’s recently approved climate plan to enact a “cap and invest” program for limiting emissions is a recent example of the country’s ongoing move toward clean renewable energy solutions

Correlate Infrastructure Partners (OTCQB: CIPI), a tech-enabled development, finance, and fulfillment platform for distributed energy solutions across North America, is at the forefront of offering climate-related technology and is pushing for its adoption amid calls for the government to address the looming climate change crisis. Banking on its finance platform, coupled with its growing product line of locally-sited energy solutions, involving solar, energy storage, electric vehicle (“EV”) infrastructure, and intelligence measures, Correlate is removing friction between today’s legacy finance process and the needed clean-energy upgrades developed within its program technologies. This allows for an easy and seamless transition toward clean, renewable energy. Recently, there has been an aggressive push for green energy alternatives at both the federal and state levels. Governmental support continues to grow, even as the country inches closer to 2050 when it is required to meet Net Zero Emissions (“NZE”) targets. This push has seen the launch of the Net Zero Government Initiative in the United States, inviting governments to lead by example. It has also seen the simultaneous push for multiple climate mitigation goals, such as achieving 100% carbon pollution-free electricity by 2035 and a Nationally Determined Contribution (“NDC”) of 50-52% reductions below 2005, covering all sectors and all gases by 2030 (https://ibn.fm/KBK1N). Achieving these goals calls for improving the energy efficiency of nearly everything – from buildings to vehicles, with a mix of mandates and incentives, according to an article published by Politico. Correlate understands this requirement, hence its unique market positioning and how it has structured its product and service offerings. The company covers all aspects of the greening and electrification process, focusing on retrofitting existing buildings, which experts note is an integral step towards reaching the 2050 carbon goals (https://ibn.fm/LfoDB). New York just approved a climate plan to enact a “cap and invest” program to limit emissions and require polluters to purchase allowances to spew greenhouse gases. This plan will require electrifying millions of homes, businesses, trucks, and cars, investing in energy efficiency improvements, and successfully siting and building thousands of megawatts of new renewable energy projects, all areas Correlate covers in its distributed energy offerings. “If there is ever a place that is going to lead the way on solving climate change, it is New York,” noted Doreen Harris, President of the New York State Energy Research and Development Authority and Climate Action Council co-chair. This move by New York indicates the country’s direction and stand on climate change. It also represents a critical step toward green energy adoption and overall emissions reductions ahead of the 2050 net zero goals. Correlate recognizes the opportunity at hand. Through its distributed energy solutions, it looks to take advantage of a looming spike in demand for renewable energy infrastructure and associated services. With a track record of providing efficient and affordable energy solutions across North America, the company is well-positioned to solve this demand while at the same time accelerating the adoption of climate-related technology in the United States. For more information, visit the company’s website at www.CorrelateInfra.com, including the following:

• Breaking Down Barriers To Your ESG Goals While Generating Additional Net Operating Income: www.CorrelateInfra.com/our-process
• Platform Generates New Rent And Operating Income, Allowing You To Meet Your ESG Goals: www.CorrelateInfra.com/program

NOTE TO INVESTORS: The latest news and updates relating to CIPI are available in the company’s newsroom at https://ibn.fm/CIPI

• Natural gas prices quadrupled over the last two years
• Electrification presented as solution to rising energy costs, global warming, and fossil fuel dependence
• Inflation Reduction Act of 2022 helps ease transition with rebates and tax credits for heat pumps
• GeoSolar’s SmartGreen(TM) Home system offers a total-home makeover, including geothermal-powered heat pump, solar panels, upgrades to insulation, windows, and lighting systems

Natural gas prices have quadrupled over the last two years (https://ibn.fm/9Kd0s). Upward pressure on prices coupled with government incentives are leading consumers to seek electric-based solutions to heat and power their homes. GeoSolar Technologies (“GST”), a climate technology company based in Colorado, helps homeowners fully maximize the shift to electrification with their SmartGreen(TM) whole-home renewable energy systems that leverage electric power while lowering bills, reducing carbon emissions, and providing unparalleled energy efficiency. Electrification is increasingly presented as a solution to rising energy costs, making SmartGreen(TM) a viable alternative that can either drastically lower or eliminate utility bills. In addition, the Inflation Reduction Act of 2022 is helping ease the transition with rebates and tax credits for heat pumps, making them more affordable in an environment of constantly increasing energy prices (https://ibn.fm/5nilP). “Ending America’s overreliance on other nations to power our clean energy future requires decisive actions that prioritize our national security and economic prosperity—and that’s exactly why President Biden is empowering DOE to expand our use of high-tech heat pumps to save energy while manufacturing them right here in the U.S.,” said U.S. Secretary of Energy Jennifer M. Granholm. “These dollars are ready to invest in American-made clean energy technologies and our workforce to ensure lower energy costs and cleaner air and water for every American.” GeoSolar’s SmartGreen(TM) Home system allows homeowners to leverage the benefits of an electric heat pump powered by geothermal ground loops. SmartGreen(TM) additionally taps into the power of the sun through photovoltaic rooftop solar panels to provide all the electricity required by the home to power appliances and charge electric vehicles. Besides providing homeowners with energy independence, SmartGreen(TM) improves building efficiency by upgrading insulation, windows, lighting systems, and the building envelope. Renewable energy technology has evolved to become viable for homeowners in both warm and cool climates. As a result, GeoSolar aims to market SmartGreen(TM) to over 120 million homes across the United States with flexible options to build the system into new construction or adapt it to existing buildings. GeoSolar is also giving the public an opportunity to get involved in the green revolution through a Regulation A+ capital raise that allows potential investors to participate with a minimum $300 investment. For more information on GeoSolar’s Regulation A+ capital raise, please visit https://www.manhattanstreetcapital.com/geosolar-technologies-inc. For more information, visit the company’s website at www.GeoSolarPlus.com. NOTE TO INVESTORS: The latest news and updates relating to GeoSolar Technologies are available in the company’s newsroom at https://ibn.fm/GST

• The 36-person human pharmacokinetic randomized, double-blind, cross-over study NIC-H22-1 will compare its patented DehydraTECH(TM)-nicotine to leading nicotine pouches On! and Zyn
• The white pouch oral delivery of nicotine is thought to avoid harmful lung outcomes that smokers and vapers experience
• The global nicotine pouch market was valued at $2.33 billion in 2020 and is expected to reach $21.84 billion by 2027, driven by an increase in the number of consumers seeking alternative forms of nicotine that do not involve lung exposure

Lexaria Bioscience (NASDAQ: LEXX), a global innovator in drug delivery platforms, announced that dosing has commenced for its human clinical nicotine study NIC-H22-1. The study is a 36-person human pharmacokinetic randomized, double-blind, cross-over study conducted on current cigarette smoking subjects. Each participant will visit the laboratory and be dosed three times over the coming weeks. Only one oral nicotine pouch will be administered and evaluated during each visit. Participants will either receive Lexaria’s patented DehydraTECH(TM)-nicotine, On! brand manufactured by Altria, or Zyn brand manufactured by Swedish Match during that time (https://ibn.fm/cz0kO).

The objectives of the NIC-H22-1 study are to determine the quantity of nicotine in blood at various time points and vital-sign data collection of temperature, blood pressure, heart rate, and respiratory rate. The company also plans to collect subjective evaluations, including throat burn, user experience, gastrointestinal experience, and more.

The global nicotine pouches market was valued at $2.33 billion in 2020 and is expected to reach $21.84 billion by 2027, growing at a CAGR of 30.7% during the forecast period (https://ibn.fm/rhGAj). Key market growth factors include a growing interest in nicotine pouches among those trying to quit smoking and the increased interest of consumers looking for alternative forms of nicotine that do not involve lung exposure.

The oral nicotine pouch category has become one of the fastest-growing segments of the nicotine industry due in part to a 2019 determination by the U.S. Food and Drug Administration (“FDA”) that stated the potential for “reduced risk health outcomes” (https://ibn.fm/CVFzR). The delivery method, in the white pouch format specifically, is thought to avoid harmful lung outcomes experienced by smokers and vapers because it involves absorption primarily through the buccal tissues of the mouth using purified nicotine that has been separated from the other harmful compounds found within the tobacco leaf.

Lexaria’s patented DehydraTECH(TM) technology is designed for formulating and delivering lipophilic (fat-soluble) drugs and active ingredients. DehydraTECH(TM) increases effectiveness and improves how these ingredients enter the bloodstream. Benefits of DehydraTECH include:

• Improved speed of onset, with effects felt in minutes
• Increased bioavailability, with more of the drug delivered into the bloodstream
• Increased brain absorption, with testing suggesting up to 10x improvement
• Improved drug potency, with more of the ingested product made available in the bloodstream requiring lower dosages

Animal studies conducted by Lexaria have demonstrated a propensity for DehydraTECH(TM) technology to elevate the quantity of the drug delivered across the blood-brain barrier by as much as 1,900 percent, which has initiated new patent applications and has opened the possibility of improved drug delivery.

As of September 2022, Lexaria’s development of its patented DehydraTECH(TM) technology since 2014 has yielded over 50 pending patents in countries worldwide, along with 27 granted patents. Lexaria’s focused ongoing research and development efforts span several key segments, including tobacco, nicotine replacement, CBD, cardiovascular drugs, antivirals, epilepsy, human hormones, and PDE5 inhibitors.

For more information, visit the company’s website at www.LexariaBioscience.com.

NOTE TO INVESTORS: The latest news and updates relating to LEXX are available in the company’s newsroom at https://ibn.fm/LEXX

• Companies that experience data breaches face, on average, $4.35 million in consequential costs, demonstrating the importance of an effective cybersecurity response
• Small to medium-sized businesses (“SMBs”) generally find the costs of hiring full-time cybersecurity experts to be prohibitive, making it difficult for them to effectively protect themselves from potential cyber crimes
• Virtual chief information security officer (“vCISO”) services are filling the breach with expert cybersecurity consultancy provided on a contract basis that is far more affordable than a full-time hire
• Cybersecurity services and technology provider SideChannel Inc. provides vCISO consultancy as well as proprietary Enclave software that addresses access control needs through microsegmentation
• SideChannel recently reported that its solutions have resulted in 71 percent YOY revenue growth with vCISO-specific services rising 93 percent and recurring software & services growing 367 percent

The industry providing virtual chief information security officer (“vCISO”) services is positioned to grow, given that cybercrime is one of the fastest-growing crimes in the United States and that the average cost of a data breach is $4.35 million, but the cost of hiring a full-time staff CISO can itself run into the hundreds of thousands of dollars, a recent Forbes report notes (https://ibn.fm/1qTwi). Virtual CISOs provide high-level security service as a consultancy contract without the need for committed staffing, offering a more affordable option. Cybersecurity services and technology provider SideChannel (OTCQB: SDCH) is demonstrating the popularity of vCISO solutions for emerging and middle market companies with its growing financial stream. SideChannel’s fiscal year-end results reported Dec. 20 note that the company’s revenue grew 71 percent YOY and vCISO revenue specifically grew 93 percent to $3.1 million. Further, recurring vCISO revenue increased by 562. “Our investments in sales and marketing, coupled with our expanding cybersecurity, privacy, and risk management capabilities, has proven to be effective at acquiring new clients and retaining existing relationships,” CEO Brian Haugli stated in a company news release (https://ibn.fm/EhMEM). The company’s vCISO engagements are typically for a 12-month period with a monthly subscription and an annual renewal option, and each of SideChannel’s vCISO’s is generally embedded into the C-suite executive teams of its clients, according to management’s notes in its annual report to the U.S. Securities and Exchange Commission (“SEC”) (https://ibn.fm/HzFTa). In addition to its vCISO solutions, SideChannel is developing new cybersecurity software and services for its customers. The company’s Enclave product rolled out in September, providing SMBs critical encryption, microsegmentation and access control. “Industry standard cybersecurity and risk management frameworks, such as National Institute of Standards and Technology Cybersecurity Framework (“NIST CSF”) and Center for Internet Security Controls (“CIS”), prioritize inventory of assets and access control as top requirements for a sustainable and compliant cybersecurity program,” the company’s SEC report states. “Enclave reduces the attack surface; which means there is less surface area to search. … Enclave reduces the time to containment by reducing the surface area visible to an intruder.” The year-end financial report states recurring software & services revenue increased by 367 percent. “The Company ended the fiscal year with a cash balance of $3.0 million on September 30, 2022. We expect to continue to effectively use our cash to fund further growth and are excited about the future,” Chief Financial Officer Ryan Polk stated. For more information, visit the company’s website at www.SideChannel.com. NOTE TO INVESTORS: The latest news and updates relating to SDCH are available in the company’s newsroom at https://ibn.fm/SDCH

• BiondVax has released statistically significant results showing efficacy of its inhaled NanoAb as anti-COVID-19 therapy, as part of a preclinical proof-of-concept animal study
• The study was conducted in collaboration with the world-renowned institutes Fraunhofer Institute for Toxicology and Experimental Medicine (“ITEM”) and The University of Veterinary Medicine Hannover (“TiHo”)
• The technology is exclusively licensed from the prestigious Max Planck Institute for Multidisciplinary Sciences and the University Medical Center Gottingen
• CEO Amir Reichman is scheduled to present in person at the Biotech Showcase (San Francisco – January 9th during JPM Healthcare conference week) and the BIO CEO & Investor Conference (New York – February 6th)

BiondVax Pharmaceuticals (NASDAQ: BVXV), a biotechnology company focused on the development, manufacturing, and commercialization of innovative immunotherapeutic products used primarily for the treatment of infectious and autoimmune diseases, recently released key financials for the quarter ending September 30, 2022, and highlighted important business updates (https://ibn.fm/NlQaQ). The company is developing a pipeline of innovative nanosized antibody (NanoAb) therapies to address diseases underserved by current treatments and with large, growing markets, including infectious and autoimmune diseases such as COVID-19, asthma, psoriasis, psoriatic arthritis and macular degeneration. BiondVax is working in collaboration with the prestigious Max Planck Institute for Multidisciplinary Sciences (MPI-NAT) and the University Medical Center Göttingen (“UMG”), both in Germany. The global infectious disease therapeutics market was valued at $115 billion in 2021. It is expected to grow at a CAGR of 4.23%, resulting in an estimated value of $167 billion by 2030. Market growth can be attributed to the rising prevalence of infectious diseases worldwide, brought into focus with the recent COVID-19 pandemic (https://ibn.fm/KUL1X). Likewise, the global autoimmune disease therapeutics market is expected to experience significant growth. Valued at $109.83 billion in 2017, the market is expected to grow at a CAGR of 4.2%, resulting in a value of $153.32 billion by 2025. The adoption of alternative treatments and the increase in the incidence of autoimmune diseases are driving factors for global growth (https://ibn.fm/4LQI1). BiondVax reported that through its collaboration with MPG and UMG, its pipeline for NanoAb therapies is proceeding according to plan. BiondVax’s lead nanosized antibody (NanoAbs) candidate is being formulated as a convenient self‑administered, inhaled COVID-19 therapy. In Germany, a preclinical proof-of-concept study of the COVID-19 NanoAb as an inhaled therapy in COVID-19-infected animals showed highly statistically significant results (p < 0.001), with the weight of the NanoAb-treated group of hamsters declining only 3.80% compared to the significant 12.01% weight loss of the control (placebo) group. This trial is expected to continue in January 2023 with testing the NanoAb at lower doses and as a prophylactic (preventative) medicine, followed by a first-in-human Phase 1/2a to be initiated during 2023. The next planned NanoAb to be tested will target IL-17 as drug candidates designed to address certain autoimmune diseases such as psoriasis. Reported in New Israel Shekels (“NIS”), BiondVax’s financials ending September 30, 2022, showed cash and equivalents of NIS 29.4 million compared to NIS 54 million as of December 21, 2021. The company had received a notice of non-compliance with NASDAQ listing rules regarding minimum Shareholders’ Equity and minimum share bid price. BiondVax quickly satisfied the requirements and has regained compliance with NASDAQ. In addition to restructuring debt repayment, the company executed a ratio change between its ordinary shares and its American Depository Shares (“ADS”) traded on NASDAQ. In late December, the company raised an additional $7.3 net in a public underwritten offering. With funding in place to continue pipeline development, BiondVax intends to initiate a first-in-human Phase 1/2a clinical trial by the end of 2023 of the inhaled COVID-19 NanoAb therapy, and also to work to expand its pipeline by adding at least one other NanoAb, possibly one to treat psoriasis. After the great interest generated during the company’s recent presentations at the HCW 24th Annual Global Investment Conference, LD Micro Main Event XV, and RAFT 14, BiondVax’s CEO Amir Reichman has scheduled to present in person at the Biotech Showcase Conference. Biotech showcase is held in parallel with the annual JPM Healthcare Conference in San Francisco on January 9-11, 2023. He will also participate at the BIO CEO & Investor Conference in New York on February 6-9, 2023. Investors and industry leaders interested in meeting with Mr. Reichman can contact BiondVax directly to schedule. For more information, visit the company’s website at www.BiondVax.com. NOTE TO INVESTORS: The latest news and updates relating to BVXV are available in the company’s newsroom at https://ibn.fm/BVXV

• MetAlert has, since its inception, sought to offer quality-of-life improvements to patients and caregivers dealing with Alzheimer’s, dementia, and autism (“ADA”)
• This focus has led to the company offering products and services within the GPS/BLE wearable technology, personal location, wandering assistive technology, and health data collection and monitoring
• Also important is MetAlert’s offering of hearing aids, ranging from its flagship Hear IQ 4 rechargeable, app-controlled hearing aid, the NRBz noise-reducing buds, HearingVite, and the Ear-Ring Relief formula
• MetAlert understands the correlation between cognitive decline and hearing loss, with persons with hearing loss who wore devices performing better on cognitive scores in the short term, according to a study published on December 5, 2022
• The company is optimistic that, as the conversation around ADA progresses, more people will start seeking early diagnosis and treatment for cognitive decline and embrace the use of hearing aids as one step to preserve cognition

MetAlert (OTC: MLRT), a pioneer in location-sensitive health monitoring devices and wearable technology products, has, since its inception, sought to offer quality of life improvements to patients and consumers who have Alzheimer’s, dementia and autism (“ADA”). This focus has yielded the design, development, manufacturing, distribution, and sale of products and services within the GPS/BLE wearable technology, personal location, wandering assistive technology, and health data collection and monitoring. All these offerings have been well-received and have proven to offer value to those afflicted with ADA. Its flagship product, GPS SmartSoles HUB, launched in the fourth quarter of the 2022 financial year, allows for remote monitoring, data collection, and encrypted data transmission to the cloud. In addition, RoomMate, MetAlert’s latest offering, allows caregivers to monitor patient behavior that could lead to falls and injuries without invading their privacy. As evidenced by these two products, MetAlert prioritizes patient confidentiality while pushing the needle regarding the use of technology to improve service delivery and the quality of life of patients afflicted with ADA. The focus on this target population has also seen MetAlert offer hearing aids, ranging from its flagship Hear IQ 4 rechargeable, app-controlled hearing aid to the NRBz noise-reducing buds. The company also offers HearingVite, a formulation proven to boost memory and cognitive function among individuals aged 50 years and above. It also offers Ear-Ring Relief, a formula that integrates vitamins, minerals, and nutritional supplements to relieve Tinnitus sufferers (https://ibn.fm/AgbFE). MetAlert understands the correlation between cognitive decline and hearing loss, hence its foray into developing and delivering hearing aids and accompanying formulations. A study published on December 5, 2022, noted that people with hearing loss who wore devices to help performed 3% better on cognitive scores in the short term. The study further established that the use of hearing aids was associated with a 19% reduction in long-term cognitive decline, making it a viable option for preventing the onset of dementia (https://ibn.fm/niT1g). “Encouragingly, even patients who already started with mild cognitive impairment (‘early dementia’) in our pooled analysis also benefitted from the use of hearing aids, as they also had approximately 20% lower risk of progressing to dementia,” noted Dr. Benjamin Tan, Dean’s Fellow at the Yong Loo Lin School of Medicine, National University of Singapore. “This means that it is never too late to start using hearing aids, but early treatment may help preserve the most cognition,” he added. Hearing aids are not the only way to prevent cognitive decline. As such, MetAlert advocates for a well-rounded, preventive approach that includes a healthy diet, vigorous physical activity, good sleep, stress reduction, and an active social life. With persons afflicted with ADA accounting for 2.9% of the world’s population or about 34 million individuals in 24 developed countries, the company understands the severity of the situation and is committed to offering solutions specific to the needs of these individuals. MetAlert’s management is optimistic that as the conversation around ADA progresses, more people will start seeking early diagnosis and treatment for cognitive decline and embrace the use of hearing aids to preserve cognition. The World Health Organization (“WHO”) estimates that by 2050, the proportion of older people will have increased to about 139 million, which will also see an increase in individuals living with ADA (https://ibn.fm/dAq4k). MetAlert hopes that early diagnosis and the use of hearing aids will help reduce these numbers while improving the lives of those who may develop these conditions over time. For more information, visit the company’s website at www.MetAlert.com. NOTE TO INVESTORS: The latest news and updates relating to MLRT are available in the company’s newsroom at https://ibn.fm/MLRT