• Turbo Energy in September 2023 announced its successful debut on the Nasdaq stock exchange
• The company operates as a subsidiary of Umbrella Solar Investment S.A.
• Turbo Energy’s total revenue for the year ended December 31, 2022, increased by 82% year-over-year to €31,148,676 (approximately $33,321,219)
• In October 2023, the company was awarded a software patent in Spain related to its flagship Sunbox product

Turbo Energy (NASDAQ: TURB) designs, develops and distributes equipment for the generation, management and storage of photovoltaic energy in Spain, Europe and internationally.

Turbo Energy’s products include lithium-ion batteries and inverters. Additionally, the company recently launched its flagship product, the Sunbox, an all-in-one device that integrates most of the equipment required for a residential photovoltaic installation. The Sunbox is powered by AI and features a software system that monitors the generation, use and management of photovoltaic energy by analyzing large amounts of data related to energy generation, consumption, market prices and weather forecasts. This AI system optimizes battery usage, reducing electricity bills and providing peak-use reduction and uninterruptible power supply functions.

Turbo Energy currently sells its photovoltaic energy equipment primarily through distributors for residential consumers in Spain, but it possesses the expertise and international perspective to expand its product portfolio into industrial and commercial scale and markets, as well as advancing the internationalization process it has already started. The company plans to expand into the industrial photovoltaic sector with its new Sunbox, launched in 2023, in higher power and capacity variants. Its goal is to become a significant player in this sector and contribute to the growth of renewable energy solutions.

The company was incorporated in 2013 and is based in Valencia, Spain. It operates as a subsidiary of Umbrella Solar Investment S.A.

Products

Lithium-Ion Batteries

Turbo Energy is one of the leading companies that introduced lithium-ion batteries for photovoltaic energy storage in Spain. Primarily for the home energy storage market, the company’s batteries have capacities from 2.24 kWh to 5.1 kWh in 24 and 48 volts. In addition, its 48V / 5.1 kWh units are available in a dual battery system.

Inverters

The inverter converts the direct current produced by the photovoltaic panels into alternating current that can be used by household appliances. It also regulates battery charging and discharging based on energy needs and optimizes utilization of generated renewable energy. Turbo Energy currently offers multiple models that cover most household installations.

All-in-One Sunbox

This product incorporates inverters, batteries and the rest of the components necessary to operate and protect the photovoltaic installation. This saves installation cost and assembly and configuration time while preventing errors. Notably, the latest Sunbox models also offer an EV charging option.

Software System

In communication with the inverter, the company’s software monitors energy flows between the photovoltaic panels, household consumption, storage and an optional electric vehicle charging station. The software allows users to customize an automatic backup mode based on weather forecasts, or manually select which part of the battery will be reserved for possible power outages. It also allows the battery to be used in a peak shaving mode, which leverages AI to trigger battery power when grid energy is most expensive, effectively reducing the amount of high-cost power drawn from the grid.

Market Opportunity

According to a report by Fortune Business Insights, a global research and reporting firm, the solar energy storage battery market was estimated to be worth $3.33 billion in 2022 and is projected to reach a value of more than $20 billion by 2030, marking a CAGR of 24.2% over the forecast period.

These batteries are crucial components of renewable energy systems, allowing for the storage of excess electricity generated by solar panels, so it can be used during times of no or low sunlight. By storing energy and supplying it when needed, these batteries reduce reliance on the power grid and maximize self-consumption while helping users avoid peak electricity rates. They also contribute to the transition toward a cleaner and more sustainable energy future by enabling residential consumers and businesses to use solar power even when the sun is not shining.

Management Team

Enrique Selva Bellvís is the CEO and founder of the Umbrella Group. In addition, he serves as vice-president of the Valencian Association of Energy Sector Companies industry group. Before his career in the solar energy sector, he was the founder and CEO of Innova Ingenieros Consultores. He holds a degree in industrial engineering with a specialization in energy from the Polytechnic University of Valencia and completed the Management Development Programme at the IESE Business School.

Mariano Soria is the Chief Innovation Officer for the Umbrella Group and serves as General Manager of Turbo Energy. He was CEO of Punt Moble XXI S.L. and continues to serve on that company’s board. Before that, he was the General Manager of REJMAR S.A., a land development company. He received his degree in industrial engineering and industrial organization from the Polytechnic University of Valencia, and his MBA from the European University of Madrid.

Alejandro Moragues is CFO of Turbo Energy. Previously, he held the position of Senior Corporate Auditor for U.S. company Euronet Worldwide Inc. and was an external auditor for PricewaterhouseCoopers. He holds a bachelor’s degree in business administration and management from the Polytechnic University of Valencia.

Manuel Cercos is Chief Commercial Officer at Turbo Energy. Previously, he held positions at Técnicas Aplicadas en Baterías S.L., where he served as Sales Director and Sales Manager. Before that, he worked as a Sales Technician at DAISA.

For more information, visit the company’s website at www.Turbo-e.com.

NOTE TO INVESTORS: The latest news and updates relating to TURB are available in the company’s newsroom at https://ibn.fm/TURB

• SenesTech Inc., a visionary leader in fertility control to manage animal pest populations, has developed products that show success in limiting rat populations using unique non-lethal fertility reduction products
• Rodents are often associated with carrying diseases that can affect humans, and SenesTech’s non-lethal population-reducing technology targets this major problem in a uniquely humane, environmentally conscious, yet effective way
• The Arizona-based company has developed two primary products — its liquid ContraPest(R) brand, and the recently introduced Evolve(TM) Soft Bait formulation, soft bait being favored by rodent control professionals
• The company anticipates using their technology to develop similar pest-control products for other species in the near future

Close on the heels of introducing a new product expected to create exponential revenue growth for the company, pest animal control innovator SenesTech (NASDAQ: SNES) reported its Q3 financial status to investors Nov. 9, highlighting the company’s continued progress in a year that has seen a record sequential quarterly increase in its earnings.

An archived recording of the Q3 report can be found on SenesTech’s Investor Relations page, at https://ibn.fm/AeEie.

SenesTech’s commitment to sustainable, non-toxic rodent reduction, is reflected in the company’s drive to market a global pest solution that introduces fertility control as the ideal alternative to toxic poisons.

Its trademarked liquid ContraPest(R) bait and Evolve(TM) Soft Bait both target the rapid birth rate in rodent populations, which can result in 15,000 offspring for a single pair of breeding rats in a year’s time and half a billion descendants within three years, according to research cited by President & CEO Joel Fruendt during an October webcast also available on the company’s archived recording webpage.

ContraPest established the company’s reputation with a brand that has shown success in reducing rat populations and subsequently increasing the profitability of poultry enterprises on both the East and West Coasts. The pest control industry’s preference for non-liquid applications then led SenesTech to formulate a non-liquid soft bait solution in its new Evolve product.

“Evolve was developed to offer customers a soft bait product that has similar efficacy to ContraPest(R), but in a format that is easier to deploy and that they can use daily in their integrated pest management programs,” Fruendt stated in a Nov. 1 news release announcing that the company is now taking orders from commercial customers for the soft bait formulation (https://ibn.fm/guMGb).

“Evolve is also suited for use by consumers,” he added, “and we expect to announce partnerships with e-commerce providers and big box retailers by the end of the year.”

The company states that Evolve is highly palatable to rats, and can be placed virtually anywhere rats are found, ranging from outdoor parks and recreation facilities to medical facilities and residential locations.

Evolve currently is only formulated for rats, although the company expects to expand to other pest species in the near future. The product’s active ingredient is a compound derived from cottonseed oil administered in doses too low to affect other species’ fertility as long as the product isn’t consumed in substantial quantities over extended periods of time, but the company recommends using tamper-resistant bait stations to minimize potential non-target species exposure.

Evolve is designed for repeated application. Its non-lethal approach to rodent birth control anticipates a cumulative effect over time with a half-life of approximately three days after consumption, and the company states rats will regain their fertility within approximately six weeks after they stop consuming the bait.

With the advent of cooler weather in the Northern Hemisphere, rodent activity becomes more noticeable because of their efforts to find warm refuge. An estimated 21 million homes across the United States will be affected by rodent activity during the season, according to pest control corporation Orkin (https://ibn.fm/ASt6r).

SenesTech’s original liquid ContraPest brand has the benefit of targeting hard-to-get roof rodents, and is the only rat contraception product for both male and female rats registered with the Environmental Protection Agency (“EPA”).

For more information, visit the company’s website at www.SenesTech.com.

NOTE TO INVESTORS: The latest news and updates relating to SNES are available in the company’s newsroom at https://ibn.fm/SNES

• D-Wave and QuantumBasel announced a two-year extension to the strategic agreement between the companies to accelerate quantum and quantum-hybrid application development in Europe
• D-Wave will open a European office on the QuantumBasel campus to establish an onsite presence supporting the companies’ joint efforts to fast-track the region’s commercialization of quantum computing
• D-Wave’s European customers include QuantumBasel, BBVA, Koç Holding, Satispay, Poznan Superconducting and Network Center, and Cineca

D-Wave Quantum (NYSE: QBTS), a leader in quantum computing systems, software, and services and the world’s first commercial supplier of quantum computers, and QuantumBasel, Switzerland’s quantum innovation hub, recently announced a two-year extension to the strategic agreement between the companies to accelerate quantum and quantum-hybrid application development in Europe.

As a part of the agreement, D-Wave will open a European office on the QuantumBasel campus to establish an onsite presence supporting the companies’ joint efforts to fast-track the region’s commercialization of quantum computing. D-Wave’s commitment to opening its European office reflects the growing regional customer interest in and usage of the company’s annealing quantum computing solutions, including the Advantage(TM) system.

Advantage is a fifth-generation annealing quantum system with 5,000+ qubits and 15-way connectivity. D-Wave has incorporated two decades of quantum technology development experience and over ten years of customer feedback to build the first and only quantum computer designed for business applications and operating today.

In addition to QuantumBasel, D-Wave’s European customers include BBVA, Koç Holding, Satispay, Poznan Superconducting and Network Center, and Cineca. Several other leading organizations also utilize D-Wave’s technology including Mastercard, Deloitte, ArcelorMittal, Siemens Healthineers, Unisys, NEC Corporation, Pattison Food Group Ltd., DENSO and Lockheed Martin.

“This extended partnership with D-Wave solidifies our shared dedication to quantum innovation in Switzerland and beyond,” said Damir Bogdan, CEO of QuantumBasel (https://ibn.fm/CA6hg). “Our collaboration is a promise to drive quantum advancements and progress towards broader commercial adoption.”

The initial strategic collaboration between D-Wave and QuantumBasel was signed in December 2022, which named D-Wave as the annealing quantum technology provider for QuantumBasel, giving the center’s tenants and customers access to the Advantage annealing quantum computer via D-Wave’s real-time Leap(TM) quantum cloud service. Since the agreement, uptownBasel and D-Wave have successfully led joint go-to-market initiatives and worked on numerous customer engagements.

Using the Leap quantum cloud service, D-Wave customers have developed quantum hybrid applications for use cases in manufacturing, logistics, financial services, life sciences, materials science, retail, and transportation. With quantum computational processing power, D-Wave is helping businesses accelerate time-to-solution for their complex computing problems. The company shares real-world quantum applications at a business scale through its client success stories (https://ibn.fm/DgnCG).

“QuantumBasel and D-Wave share a vision of solving the world’s most complex problems for the betterment of industry and society. Today’s announcement reflects strong progress toward achieving that mission, as joint customers are quickly realizing the near-term advantage of D-Wave’s quantum technology,” said Dr. Alan Baratz, CEO of D-Wave. “Through our collaboration and now our European office presence, we anticipate accelerated momentum for quantum and quantum-hybrid applications moving into production and fueling operations.”

For more information, visit the company’s website at www.DWaveQuantum.com.

NOTE TO INVESTORS: The latest news and updates relating to QBTS are available in the company’s newsroom at https://ibn.fm/QBTS

Forward-Looking Statements

Certain statements in this press release are forward-looking, as defined in the Private Securities Litigation Reform Act of 1995. These statements involve risks, uncertainties, and other factors that may cause actual results to differ materially from the information expressed or implied by these forward-looking statements and may not be indicative of future results. Forward-looking statements in this press release include, but are not limited to, statements regarding the opening of D-Wave’s European office, and the potential benefits of D-Wave’s European presence and the continued collaboration between D-Wave and QuantumBasel. These forward-looking statements are subject to a number of risks and uncertainties, including, among others, various factors beyond management’s control, including the availability of office space at QuantumBasel, general economic conditions and other risks; the company’s ability to expand its customer base and the customer adoption of its solutions; risks within D-Wave’s industry, including anticipated trends, growth rates, and challenges for companies engaged in the business of quantum computing and the markets in which they operate; the outcome of any legal proceedings that may be instituted against the company; risks related to the performance of the company’s business and the timing of expected business or financial milestones; unanticipated technological or project development challenges, including with respect to the cost and/or timing thereof; the performance of the company’s products; the effects of competition on its business; the risk that the company will need to raise additional capital to execute its business plan, which may not be available on acceptable terms or at all; the risk that D-Wave may never achieve or sustain profitability; the risk that the company is unable to secure or protect its intellectual property; volatility in the price of the company’s securities; the risk that the company’s securities will not maintain the listing on the NYSE; and the numerous other factors set forth in D-Wave’s Annual Report on Form 10-K for its fiscal year ended December 31, 2022 and other filings with the Securities and Exchange Commission. Undue reliance should not be placed on the forward-looking statements in this press release in making an investment decision, which are based on information available to the company on the date hereof. The company undertakes no duty to update this information unless required by law.

GolfLync, a leading social networking hub for golf lovers, is revolutionizing the online golfing world. Recently, influencers from various platforms have been flocking to GolfLync, bringing along their followers. This trend has led GolfLync to introduce an array of features aimed at enabling these influencers to broaden their reach and grow their brand. This integration not only enhances the visibility of influencers but also provides them with tools to manage and rotate posts across the feeds.

In an effort to bolster the credibility and authenticity of its influencer community, GolfLync has implemented a new verification process. Influencers can now apply for verification using a government-issued ID, earning a distinctive blue verification mark on their accounts. Incentive programs are being offered to select influencers to build their brands on the platform to earn a gold badge and top rewards in our program. Influencers can apply for influencer status in-app. For more information, please visit www.GolfLync.com/influencer-features.

This mark serves as a badge of authenticity, protecting the brand identity of influencers and instilling trust among their followers. Furthermore, GolfLync will be releasing a dedicated filter for staying updated on influencers, making it easier for members to discover and receive content from prominent figures in the golfing world. This dedicated filter not only elevates the visibility of influencers but also enriches the member experience by providing curated, high-quality golf content.

GolfLync is a game-changer for the platform and its users, and will also be introducing the integration of seamless content sharing between Instagram and Facebook. This feature enhances the golfing journey by enabling users to effortlessly share their golfing experiences and insights across their social networks. By doing so, it fosters a more interconnected and vibrant golfing community, where experiences and tips are freely exchanged, thus enriching the overall member experience.

GolfLync’s commitment to maintaining a genuine and safe online environment is further exemplified through enhanced reporting tools. Users now have the power to report spam and bots effectively, safeguarding the platform’s authenticity and ensuring a high-quality experience for all members. Additionally, the introduction of an in-app verification application process is a significant stride in enhancing trust and recognition within the GolfLync community. This feature allows users to apply for verified status, thereby elevating their profile within the golfing network.

These latest enhancements by GolfLync are more than just features; they represent a holistic approach to taking golf networking to unprecedented heights. By intertwining social media functionality with a dedicated golfing platform, GolfLync is setting a new standard in digital golf networking. Explore these exciting new features today and experience the evolution of golf social networking.

About GolfLync
GolfLync is the ultimate social media platform for golfers, connecting like-minded enthusiasts, fostering vibrant golfing communities, and redefining the golfing experience. With a user-friendly interface and advanced features, GolfLync brings golfers together and provides a space for golfers to connect, share, and celebrate their shared passion. Download the GolfLync app today and explore the world of golf like never before!

For more information about GolfLync and the groundbreaking initiatives that are transforming the golfing landscape, visit the company’s website at GolfLync and be part of a revolution in golfing camaraderie.

GolfLync APPs are available for free from both the Apple Store ‎GolfLync and Google Play GolfLync – Apps on Google Play.

NOTE TO INVESTORS: The latest news and updates relating to GolfLync are available in the company’s newsroom at https://ibn.fm/GOLF

• Diamond Lake Minerals is multi-strategy operating company focused on building, acquiring and developing companies within a wide variety of industries
• DLMI’s strategy involves bridging generations of investors with accessible digital investment technology in sectors ranging from music and entertainment to real estate, healthcare and digital tokens
• Security token-centered ecosystems are gaining traction around the world, providing digital alternatives to traditional investments such as stocks or bonds — digital investments that may nonetheless deliver rights to assets that have real value
• DLMI is conscientious about the need to comply with SEC regulations and provide transparency to its shareholders, drawing on the decades of experience held in reserve by the company’s executive team

Earlier this year, one of South Korea’s biggest commercial banks — NongHyup — established a security token-centered ecosystem that has produced a consortium joined by other large banks in the country (https://ibn.fm/rsKhn). This month, brokerage firm Cathay Securities announced it had become the first financial investment company in Taiwan to gain authorization to launch that country’s first security token offering (“STO”) business, showing the continued growth of STOs globally (https://ibn.fm/cVZ1f).

Multi-strategy operating company Diamond Lake Minerals (OTC: DLMI) is establishing its own profound take on a vertically integrated ecosystem for digital assets and SEC-registered security tokens in North America.

Leaving behind its long-standing efforts as a mineral mining holding enterprise, DLMI is drawing on the strengths and vision of an experienced executive team to build an engine that powers digital wealth across generations with diverse expectations and approaches to technology.

STOs first appeared around 2019 and have been becoming increasingly popular across a number of blockchain ecosystems as digital alternatives to traditional investments such as stocks or bonds, that may nonetheless deliver rights to assets that have real value such as share ownership in real estate, investment funds and artwork.

Key to DLMI’s mission is its adherence to U.S. Securities and Exchange Commission (“SEC”) regulations and its emphasis on transparency, liquidity and security. The company is industry-agnostic, working to start, acquire and build enterprises as a parent company in sectors ranging from music and entertainment to real estate, healthcare and digital tokens.

Underscoring that purpose, DLMI sees a need to also provide the public with an education about digital assets at what appears to be a new frontier for financial markets. Importantly for the public, investing in DLMI stock is a good way of getting into digital assets, without actually having to figure out how to buy things like crypto, making DLMI stock a simple all-encompassing way to move comfortably into this growing market.

“By enabling digital assets to be traded via protocols, tokenization promises immediate settlement and lower transaction costs,” Benzinga stated in a Nov. 9 news analysis of the company’s operation (https://ibn.fm/KQxsu).

“What we’re doing is bringing back value to our shareholders in the form of highly coveted stock, something that will resemble, as we continue to perform and work, … a Berkshire Hathaway”, CEO Brian J. Esposito said during a recent interview with Benzinga Partner Studio (https://ibn.fm/ItacN). “What we want to do is give power back to investors to understand what they’re holding.”

For more information, visit the company’s website at www.DiamondLakeMinerals.com or LinkedIn page at www.LinkedIn.com/company/Diamond-Lake-Minerals/.

In addition, for information on the company’s security token SEC regulated exchange partner INX, and the development of the INX Way, visit https://www.inx.co/inx-ebook/. This free security token bible, written with the SEC on the rollout of security tokens and the future of digital assets, will greatly deepen your understanding of security tokens.

NOTE TO INVESTORS: The latest news and updates relating to DLMI are available in the company’s newsroom at https://ibn.fm/DLMI

• Fr8Tech CEO recently wrote a letter to shareholders summarizing the company’s financial milestones and operational successes
• CEO Javier Selgas discussed the company’s robust revenue growth in Q2 2023 as well as the 93% year-over-year increase in its gross margins during the first half of the year
• The company’s commitment to innovation has led to the launch of an LTL offering and the establishment of an AI department
• Fr8Tech has successfully expanded into new markets, completed a number of strategic integrations with third-party solutions, and grown its customer base

Freight Technologies (NASDAQ: FRGT) (“Fr8Tech”), a technology company whose lead product is Fr8App, an industry-leading freight-matching platform powered by artificial intelligence (“AI”) and machine learning, is making substantial strides in the realization of its objectives. In a letter to shareholders, CEO Javier Selgas summarized the company’s recent financial milestones and operational successes that underscore its commitment to achieving continued growth (https://ibn.fm/21HPi).

This growth is reflected in Fr8Tech’s financial results for the second quarter of 2023, which ended June 30, 2023. The company, Selgas wrote, “achieved robust revenue growth, marking a substantial 29% increase compared to the preceding quarter.” Selgas observed the growth attests to Fr8Tech’s “strong market positioning and effective execution of our business strategy.” The company expects to achieve at least an 8% quarter-over-quarter improvement (32% annualized) in revenue for the third quarter of 2023. Remarkably, the Q2 2023 revenue growth came at a time when average freight rates in the U.S. during the first half of calendar 2023 were between 15% and 25% lower than periods in 2022, according to Selgas.

Fr8Tech also reported a 93% year-over-year increase in its gross margin during the first six months of the 2023 fiscal year. “This improvement reflects our successful implementation of sound cost management practices and operational efficiencies, including our decision to discontinue unprofitable segments in various lines,” explained Selgas.

To further bolster its growth prospects, the company has doubled down on innovation, birthing products like the Less-Than-Truckload (“LTL”) shipping offering. According to a July 25 news release, the expansion of Fr8App’s capabilities to include support for LTL shipping was aimed at catering to the growing demands of Fr8App clients importing from Asia (https://ibn.fm/Dj84q).  The LTL offering, Selgas highlighted, has garnered a positive response from customers and industry experts alike. “This is a seed that we have planted that we expect to nurture and grow over time and is a line of business that we expect will generate higher margins relative to sales than some of our legacy products,” Selgas continued.

Moreover, in line with its commitment to innovation, Fr8Tech established a dedicated AI department. Led by a team of seasoned experts in the field of AI – including Dr. Umberto León-Domínguez, a specialist in the field of neuroscience research and in innovation and development of digital business and the current Director of AI at Fr8Tech (https://ibn.fm/5Ar8s) – the department is poised to revolutionize how the company approaches supply chain management.

“By harnessing the power of AI, we aim to develop cutting-edge functionalities and tools that will enhance efficiency and internal control, optimize logistics, and unlock unprecedented insights within the supply chain industry,” explained Selgas. “We believe that this strategic initiative will not only solidify our position as industry leaders but also deliver long-term benefits to our stakeholders by streamlining operations, improving our internal control environment, reducing costs, and ensuring our supply chain remains agile in the face of ever-evolving challenges.”

The quest for continued growth has also seen the company successfully expand into new markets, creating additional revenue streams and diversifying its customer base. For instance, the company expanded operations to El Paso, Texas, the second busiest U.S.-Mexico land port, representing about 10% of the total U.S.-Mexico cross-border freight market in the 12 months to August 2021 (https://ibn.fm/bKpAL). In addition, Fr8Tech increased the number of lanes to transport goods to or from Canada.

Fr8Tech has completed numerous strategic integrations with GPS providers, leading tech logistics companies, and numerous other industry partners. For instance, in September, the company announced a new integration with Geotab’s Open API, which is set to provide real-time visibility and improve efficiency for shippers and carriers (https://ibn.fm/Jv9zl).

This followed the May integration with Trucker Tools, one of the most utilized carrier relationship management platforms in the U.S. (https://ibn.fm/7J7Ne), and the June integration with Samsara that enables Fr8App customers to benefit from real-time GPS tracking, streamlined compliance management, and advanced diagnostic reporting (https://ibn.fm/RmEme). These collaborations, Selgas explained, enable Fr8Tech to offer real-time tracking, predictive analytics, and streamlined logistics solutions, solidifying its position as the go-to choice for cross-border shipping needs.

Other notable operational successes Selgas discussed are the company’s move to join the Mexican Association of Cargo Agents (“AMACARGA”) and the expansion of its customer base, which now includes Samsung, Whirlpool, Beat Box, Kimberly Clark, and more.

For more information, visit the company’s website at www.Fr8Technologies.com and its freight matching platform information site at www.Fr8.App.

NOTE TO INVESTORS: The latest news and updates relating to FRGT are available in the company’s newsroom at https://ibn.fm/FRGT

Corporate Communications
IBN (InvestorBrandNetwork)
Los Angeles, California
www.InvestorBrandNetwork.com
310.299.1717 Office
Editor@InvestorBrandNetwork.com

• Clene recently released its financial results for the third quarter ended September 30, 2023, and provided recent operating highlights for its ALS clinical program
• The ALS clinical program includes two independent studies evaluating the safety and efficacy of the company’s lead investigational product CNM-Au8(R)
• The 24-month long-term data cut from the open-label extension of the RESCUE-ALS study showed a significant median survival benefit of 19.3 months, a significant 52% decreased risk of ALS clinical worsening events, and a 75% decreased risk of long-term all-cause mortality
• Clene also summarized long-term follow-up data from the HEALEY ALS platform trial, which demonstrated significantly improved survival among patients treated with CNM-Au8
• The company closed Q3 2023 with $42.1 million in cash, cash equivalents, and marketable securities, expected to be sufficient to fund operations into Q3 2024

Clene (NASDAQ: CLNN) and its wholly owned subsidiary Clene Nanomedicine Inc., a clinical-stage pharmaceutical company focused on the discovery, development, and commercialization of a pipeline of novel clean-surfaced nanotechnology therapeutics for the treatment of central nervous system disorders, including Amyotrophic Lateral Sclerosis (“ALS”), multiple sclerosis (“MS”), and Parkinson’s disease (“PD”), recently released its financial results for the third quarter of fiscal 2023, ended September 30, and provided recent operating highlights for its ALS clinical program (https://ibn.fm/Y3sks).

The recent operating highlights covered the Clene’s RESCUE-ALS study, a Phase 2 multicenter, randomized, double-blind, placebo-controlled group trial investigating the efficacy, safety, pharmacokinetics, and pharmacodynamics of the company’s lead investigational product CNM-Au8(R) in patients with early symptomatic ALS, and Phase 2/3 HEALEY ALS platform trial, a perpetual multicenter, randomized, double-blind, placebo-controlled clinical trial program evaluating the efficacy and safety of multiple investigational products, including CNM-Au8, in patients living with ALS.

In August, Clene reported a 24-month long-term data cut from the open-label extension (“OLE”) of the RESCUE-ALS study as of July 2023, which showed a significant median survival benefit of 19.3 months in addition to a significant (p=0.049) 52% decreased risk of ALS clinical worsening events  – defined as the first occurrence of death, tracheostomy (a procedure that involves creating an opening in the neck into the windpipe to help air and oxygen reach the lungs), assisted ventilation, or feeding tube placement – in patients originally treated with CNM-Au8. The data also showed a 75% decreased risk of long-term all-cause mortality (https://ibn.fm/1BM6Q).

A month later, in September, the company reported long-term follow-up data for patients treated with CNM-Au8 for up to 133 weeks in the OLE of the HEALEY ALS platform trial. The post hoc results showed significantly improved survival compared to matched historical placebo controls from previously completed Phase 2 and Phase 3 ALS trials stored in the Pooled Resource Open-Access ALS Clinical Trials (“PRO-ACT”) database, the largest U.S. clinical database of previous ALS trials.

The significantly improved survival finding was based on two analyses. The first analysis compared 59 participants originally randomized to CNM-Au8 30mg in the HEALEY ALS platform trial to matched placebo participants derived from the PRO-ACT dataset. The analysis revealed a statistically significant (p=0.046) 49% decreased risk of death compared to placebo controls. Secondly, the company conducted a pooled analysis of the HEALEY ALS platform trial and the RESCUE-ALS clinical trial, comparing results from 82 participants originally randomized to CNM-Au8 30mg to matched placebo controls. This second analysis demonstrated a statistically significant (p=0.004) 59% decreased risk of death compared to placebo (https://ibn.fm/oGbvH).

“We are pleased to be approaching a meaningful regulatory discussion with the U.S. Food and Drug Administration (‘FDA’) later in the fourth quarter to elucidate key next steps in our ALS regulatory submission of CNM-Au8,” conveyed Rob Etherington, President and CEO of Clene. “We are hopeful that the consistent survival, delayed time to clinical worsening, and strong safety profile with CNM-Au8 treatment from two phase 2 independent trials is sufficiently compelling for FDA to consider an accelerated path forward. The unmet need remains high for treatments to improve and extend life for patients living with this highly debilitating rapidly progressive condition.”

Clene also reported the publication in September of a scientific paper describing the catalytic mechanism of action of CNM-Au8 in the journal Small. Titled “A Mechanism Underpinning the Bioenergetic Metabolism-Regulating Function of Gold Nanocatalysts,” the open-access publication characterizes the robust neuroprotective properties of CNM-Au8 (https://ibn.fm/2WuHz).

Along with the recent operating highlights, Clene also reported financial highlights from the third quarter, key among them its financial position. The company closed Q3 2023 with $42.1 million in cash, cash equivalents, and marketable securities, including gross proceeds of $40 million from a June 2023 public offering. The offering may provide additional capital of up to $130 million through future warrant exercises based on regulatory milestones (https://ibn.fm/Rv5g2). Clene expects the resources on hand as of September 30 to be sufficient to fund its operations into Q3 2024.

Meanwhile, Clene, in collaboration with Columbia University and Synapticure, was awarded a four-year $45.1 million grant from the National Institute of Neurological Disorders and Stroke (“NINDS”), a division of the National Institutes of Health (“NIH”). The grant will support an Expanded Access Protocol (“EAP”) for the CNM-Au8 in ALS, allowing patients who did not meet the criteria to enroll in the two independent clinical trials to access the investigational drug, even though the FDA does not yet approve it.

For more information, visit the company’s website at www.Clene.com.

NOTE TO INVESTORS: The latest news and updates relating to CLNN are available in the company’s newsroom at https://ibn.fm/CLNN

• Ucore, a company engaged in the exploration for plus separation and scalable production of REEs, just announced a technical update on its RapidSX(TM) Demonstration Plant in Kingston, Ontario
• Mike Schrider, the company’s VP and COO, lauded this milestone, noting how it ultimately led to optimizing the chemistry delivery and feedback systems to and from the RapidSX(TM) platform within the plant
• These steps will lead the way to demo plant commercialization, scale-up, and technology transfer, for its developing 7,500 tonnes per annum (ex-cerium and ex-yttrium) REE separation plant – the Louisiana Strategic Metals Complex (“LA-SMC”) in Alexandria, Louisiana

Ucore Rare Metals (TSX.V: UCU) (OTCQX: UURAF), a company engaged in the exploration for rare earth elements (“REEs”) in Canada and the U.S., as well as the associated development of superior separation and scalable production technologies, just announced a technical update on its important RapidSX(TM) Demonstration Plant in Kingston, Ontario. The update marks a significant milestone for the company, and will allow them to “discreetly quantify the previous qualitative attributes of the RapidSX(TM) technology platform and the resulting rare earth element products” (https://ibn.fm/3HrKh). Mike Schrider, Ucore’s Vice President and Chief Operating Officer, lauded this milestone, attributing it to his team’s approach to optimization and fine-tuning efforts. He also noted how this ultimately led to optimizing the chemistry delivery and feedback systems to and from the plant’s RapidSX(TM) platform. “Over the first two years in Kingston, we proved the technical superiority of our now patent-pending RapidSX(TM) technology platform to mix and separate the chemistry of solvent extraction,” noted Mr. Schrider. “We have since taken those optimization and fine-tuning efforts and engaged in a robust engineering, construction, commissioning, testing, and demonstration effort to truly optimize the chemistry delivery and feedback systems to and from the RapidSX(TM) platform within the Demo Plant and across all of the related systems within the Commercialization and Demonstration Facility (‘CDF’),” he added. Ucore has been and still is working to ensure best-in-class processing metrics and quantity of its RapidSX(TM) benefits through a rigorous engineered demonstration program for the U.S. Department of Defense at its Louisiana Strategic Metals Complex (“LA-SMC”) in Alexandria, Louisiana. The company is also exploring commercial processing of a growing range of heavy and light mixed rare earth chemical concentrates originating from various mineralization sources. So far, three different feedstock sources have been included in the work at the CDF, highlighting the facility’s potential and the overall viability of its RapidSX(TM) technology platform. This technical update follows Ucore’s recent announcement of its RapidSX(TM) positioning to overcome obstacles and disrupt the rare earth elements market. Having proven the technology against standard CSX solvent refining processes, typically used in China, the company is confident that its technology is superior, more efficient, and cost-effective. This technical update echoes that and brings Ucore closer to disrupting the market. For more information, visit the company’s website at www.Ucore.com. NOTE TO INVESTORS: The latest news and updates relating to UURAF are available in the company’s newsroom at https://ibn.fm/UURAF

• SuperCom’s wholly owned subsidiary, Leaders in Community Alternatives, Inc. (“LCA”), recently won a new contract to supply alcohol monitoring technologies and services in California
• The contract is valued at up to $3 million over the initial 3-year term, based on anticipated usage estimates
• Since 2003, LCA has provided continuous transdermal alcohol monitoring (“CAM”) programs for thousands of California drivers found driving under the influence (“DUI”)
• The alcohol monitoring programs use tamper-proof tags worn around the ankle to measure the amount of alcohol in an offender’s body by taking a sample of their sweat every 30 minutes
• SuperCom’s reputation for providing reliable and high-quality electronic monitoring services was pivotal in securing the new contract, President and CEO Ordan Trabelsi said

SuperCom (NASDAQ: SPCB), a leading global provider of traditional and digital identity solutions, provides advanced safety, identification, connectivity, and security products and solutions to governments as well as public and private organizations around the world. The Tel Aviv, Israel-headquartered company wholly owns several active subsidiaries, including, among others, Leaders in Community Alternatives, Inc. (“LCA”).

Acquired in January 2016, LCA is a California-based, private criminal justice organization running electronic monitoring programs and providing community-based services under contracts with various government agencies in the United States. According to SuperCom, LCA has significantly bolstered the company’s competitive edge in competitive tenders, “allowing us to offer not only cutting edge technology, but also extensive industry experience. We have since then beat market competitors in competitive processes and have been awarded projects in various countries around the world, including USA, Canada, Latvia, Czech Republic, Denmark, Bulgaria, and other countries in Europe and Asia” (https://ibn.fm/3uDmh).

SuperCom expresses confidence that previous success in countries around the world, coupled with the status of active tenders, position it to win additional new projects in years to come. The company has remained committed to fostering strong partnerships and relationships with customers, driving technological advancements, and delivering top-tier solutions that address the unique challenges of the criminal justice system.

This summer, LCA secured a new contract to provide alcohol monitoring technologies and services in support of California’s criminal justice system (https://ibn.fm/jJr7m). The contract – which is already in effect and set to run until 2026, with the possibility for future extensions – is valued at up to $3 million over the initial 3-year term, based on anticipated usage estimates. However, the actual revenue will depend on the actual usage of the alcohol monitoring solutions and services, given that customers are billed at a per-unit daily rate.

“Our reputation for providing reliable and high-quality electronic monitoring services was pivotal in securing the contract,” conveyed SuperCom President and CEO Ordan Trabelsi (https://ibn.fm/AKLZK). “This contract marks another strong achievement, building on our track record of securing numerous new electronic monitoring contracts in the U.S. and Europe. We are proud to have been chosen once again to support California’s criminal justice system. Our long-standing relationships with county customers and law enforcement underscores their trust in our technology and services.”

Since 2003, LCA has provided continuous transdermal alcohol monitoring (“CAM”) solutions for thousands of California drivers arrested for, charged with, or convicted of driving under the influence (“DUI”). The solutions use automated transdermal testing devices – tamper-proof tags worn around the ankle – that measure the amount of alcohol in an offender’s body by taking a sample of their sweat every 30 minutes (https://ibn.fm/kADzT).

The results are remotely transmitted from the tags to base stations at the participants’ homes at specific times during the day. The base stations then relay the results of the tests to a monitoring center for analysis. If alcohol is detected, the monitoring center sends a notification to the court, which may require the defendant to be taken into custody.

Electronic alcohol monitoring devices are offered in lieu of bail, allowing a defendant to remain out of custody as they await their case to be heard or as an alternative to imprisonment. It also serves as a deterrent to alcohol consumption, preventing accidents, injuries, or deaths that may arise from DUI cases.

In addition to the tags, law enforcement agencies can also use LCA’s SL2, the first handheld mobile breath device to provide discrete remote alcohol monitoring. SL2 lets participants measure their exact breath alcohol content (“BAC”) at any time at their current location; the testing can be random, scheduled, or on-demand. The device simplifies the monitoring process, all while providing the benefits of electronic alcohol monitoring.

“With a focus on technology innovation and global expansion, SuperCom is well-positioned to help lead the electronic monitoring industry in the future,” concluded Ordan.

For more information, visit the company’s website at www.SuperCom.com.

NOTE TO INVESTORS: The latest news and updates relating to SPCB are available in the company’s newsroom at http://ibn.fm/SPCB

• PaxMedica is developing PAX-101, which utilizes the company’s proprietary source of suramin sodium, for the treatment of ASD (Autism Spectrum Disorder)
• There is no FDA-approved treatment for the core symptoms of autism, even though the rates of autism spectrum disorder have jumped significantly from 2000 to 2020
• ASD is characterized by deficits in social communication, restricted and repetitive patterns of behavior, and significant impairment in functioning, three core aspects of the disease that PaxMedica aims to address
• The company announced positive topline results from a Phase 2 study evaluating PAX-101 as a potential treatment for ASD and hopes to replicate these results in a larger trial, for which PaxMedica is preparing

In the U.S., the rates of autism spectrum disorder (“ASD”), a diverse group of early-onset and lifelong neurodevelopmental conditions, have more than quadrupled from 2000 to 2020, according to data published by the Centers for Disease Control and Prevention (“CDC”) (https://ibn.fm/fRYhj). Researchers attribute the increase to advances in diagnostic capabilities as well as greater understanding and awareness of ASD (https://ibn.fm/v6gtI). PaxMedica (NASDAQ: PXMD) is a clinical-stage biopharmaceutical company intent on developing novel anti-purinergic therapies (“APTs”) for the treatment of ASD and other serious conditions.

Estimates from the CDC’s Autism and Development Disabilities Monitoring (“ADDM”) Network, which pools data from multiple sites across the United States, showed that about 1 in 36 children had been identified with ASD in 2020, up from 1 in 150 in 2000. Correspondingly, the combined prevalence per 1,000 children had grown from 6.7 in 2000 to 27.6 in 2020. Globally, the World Health Organization (“WHO”) estimates that about 1 in 100 children has ASD, although the actual figure could well be higher.

“The prevalence of ASD makes it one of the most frequent neurological development disorders, representing a major public health concern,” reads a 2021 study published in Frontiers in Neurology (https://ibn.fm/NjVlE). But even more concerning, ASD affects each person differently, meaning there is no one-size-fits-all approach to diagnosing or treating the disorder.

ASD is generally characterized by difficulty, at least to some degree, in communication and social interaction, as well as unusual repetitive behavior. Patients also present impairment in functioning. These characteristics usually manifest before the age of three years, with some children presenting limited nonverbal and verbal communication by the time they are 18-24 months old (https://ibn.fm/fRD9B). However, the symptoms are heterogeneous. This means that while some children and adults can perform all activities of daily living, others require constant supervision and substantial support to perform basic activities.

Unfortunately, the need to provide constant support often takes a toll on parents who are primary caregivers of children affected with ASD, with many experiencing higher levels of stress and poorer physical health compared to parents of children with normal development (https://ibn.fm/Y6UCE). But amid such demanding circumstances, parents and families affected by ASD typically still hope to help their children progress into adulthood with more independence, a chance for a higher quality of life, and a greater sense of well-being.

With no FDA-approved treatment currently available for the core symptoms of ASD, PaxMedica is intent on developing an important new treatment option, PAX-101, for the treatment of autism, in effect boosting the prospects of independence and lightening the burden on caregivers. PAX-101 utilizes the company’s proprietary source of suramin sodium, a therapy that has existed for more than 100 years. Suramin sodium was developed and used to treat early-stage East African sleeping sickness or Human African Trypanosomiasis (“HAT”).

In 2021, PaxMedica announced positive topline data from its 14-week Phase 2 clinical trial evaluating PAX-101 as a potential treatment for the core symptoms of ASD. PAX-101 demonstrated sustained improvements over placebo. The trial enrolled 52 patients from six sites across South Africa. The results from this trial clearly showed promise for advancing this novel treatment into the next phase of development, according to investigators (https://ibn.fm/ifm1r).

Accordingly, PaxMedica intends to confirm these results in a larger study and is preparing for the next clinical trial investigating PAX-101 as a treatment for ASD (https://ibn.fm/Sg0E2). PaxMedica hopes to capture a share of the global ASD therapeutics market, expected to grow to $3.42 billion by 2030, up from $2.01 billion in 2023 (https://ibn.fm/JtAI7).

For more information, visit the company’s website at www.PaxMedica.com.

NOTE TO INVESTORS: The latest news and updates relating to PXMD are available in the company’s newsroom at https://ibn.fm/PXMD