• Renforth Resources Inc. is a mineral exploration company engaged in the acquisition, exploration and development of mineral properties in Canada
• The company holds gold and battery mineral resources in Quebec’s mining heartland
• Renforth Resources in July 2024 resumed exploration on its Parbec Gold Deposit, consisting of a surface soil sampling and prospecting campaign
• The company in July 2024 received a C$262,500 grant from the Province of Quebec to identify and study the metallurgical characteristics of the Victoria mineralization

Renforth Resources (CSE: RFR) (OTCQB: RFHRF) is an active mineral exploration company engaged in the exploration and development of the company’s wholly owned multi-commodity mineral properties in Canada. The company owns the Parbec gold deposit on the Cadillac Break in Quebec and is currently exploring the Parbec property to increase the gold resource and identify a location to strip and bulk sample from surface.

In addition, the company holds the Nixon Bartleman gold property in Ontario and is also engaged in developing its wholly owned Malartic Metals Package, Quebec’s newest polymetallic battery minerals district with several areas of mineralization, one of which is the nickel, cobalt, copper and zinc mineralized Victoria structure boasting approximately 20 kilometers of strike with surface mineralization, limited drilling, road access and hydroelectric power.

Renforth is well positioned in the heart of the Abitibi Greenstone belt, which straddles the Canadian Provinces of Ontario and Quebec, on both of the Cadillac-Larder Lake and Destor-Porcupine faults – the two main structures responsible for a belt endowed with more than 300 million ounces of gold (including production, M&I reserves and resources to date), making it one of the world’s most prospective gold regions.

The Canadian Malartic Mine, one of Canada’s largest gold mines, is adjacent to each of Renforth’s brownfield Malartic area properties, the Parbec open pit gold resource and the Malartic Metals Package, which, in addition to several known battery metals mineralized structures, also hosts gold within the Pontiac sediments, a very under-explored geological setting.

The company is headquartered in Pickering, Ontario.

Projects

Parbec Gold Deposit

Renforth’s 100% owned Parbec Gold Deposit contains a gold resource designed with an open pit to capitalize on Parbec’s surface mineralization. An MRE on the project, effective December 2019 and now considered by Renforth to be obsolete, is based upon approximately 28,000 meters of drilling which occurred between 2007 and 2019.

Renforth drilled 15,000 meters of new holes in 2020 and 2021 which were not included in the MRE, but which did extend the mineralization deeper within the MRE. The 2020-21 drilling is considered to have validated an additional 13,000 meters of historic drilling from 1986-93.

The validation occurs as 10% of the historic holes were redrilled, with results comparable to the historic results in terms of geology and gold values. Any future MRE calculated at Parbec will benefit from the inclusion of the new and historic drilling.

In addition to this, Renforth’s current structural interpretation on the location of, and controls on, the gold mineralization at Parbec is materially different than the geological model for the outdated MRE. For the first time, Renforth has mapped the Pontiac contact and interpreted a hinge fold interacting with the Cadillac Break and allowing the movement of gold enriched fluids, with mineralization plunging to the south, into the Pontiac.

It is worth noting that a structural control on the adjacent, and much larger, Canadian Malartic Mine is the Sladen Fault transiting into the Pontiac. Currently, Renforth is testing this interpretation with a soil survey designed to outline an area for stripping and bulk sampling within the Pontiac south of the Cadillac Break.

Malartic Metals Package

Renforth’s wholly owned approximately 300-square-kilometer Malartic Metals Package in Quebec’s mining heartland includes surface mineralization of battery metals nickel, cobalt, copper, zinc and silver in separate structures, as well as a copper/silver discovery and gold mineralization. Lithium is also present in anomalous amounts in the sediments, though the source has not yet been located.

The property was assembled commencing in 2020 by adding claims to Renforth’s existing Malartic West property by map staking. The goal was to acquire historic gold and base metal showings, as well as pronounced magnetic anomalies, joining several of the areas of discrete historic exploration into a district scale property with several areas of interest for battery metals and a greenfield copper/silver discovery. The property benefits from its location in an established mining community, roads on the property, rail just off the property and hydroelectric power lines crossing the property, making logistics simple and the cost to operate quite low.

This is the first time this property has been assembled as it is today and actively explored. A significant portion of the property has never been explored.

Market Overview

The World Gold Council, the industry association for the world’s gold producers, estimated in 2023 the physical financial gold market, which is made up of bars, coins, gold ETFs and central bank reserves, is worth nearly $5 trillion. The council reports that gold mine production adds approximately 3,500 tons of the precious metal to the world’s supply annually, equivalent to about 2% growth.

This historical scarcity and relatively slow production of new supply, as compared to other commodities, is a primary reason gold has retained its value for millennia, according to the council. In August 2024, the market price of gold was approximately $2,435 per ounce.

Management Team

Nicole Brewster is President and CEO of Renforth Resources. During her tenure she has reconstituted the company, developed a maiden mineral resource and sold a gold deposit. She is a native of the Toronto area and has been around the mining business nearly all her life, having been raised by a successful mineral exploration geologist who worked (and is still working) around the world as an entrepreneur and geoscientist.

Ms. Brewster worked summer jobs in various segments of the mining business, which led to her employment as a contractor working in the early days of the digitization of exploration data, 3D modeling and data visualization. After working in the capital markets for a time, she returned to the mineral exploration business as a partner in a successful private firm with several employees.

For more information, visit the company’s website at www.RenforthResources.com.

NOTE TO INVESTORS: The latest news and updates relating to RFHRF are available in the company’s newsroom at https://ibn.fm/RFHRF

• Annovis Bio’s lead compound, buntanetap, shows significant enhanced cognitive benefits when combined with GLP-1 agonist dulaglutide in a mouse model
• Buntanetap targets neurodegenerative conditions like Alzheimer’s and Parkinson’s diseases
• GLP-1 agonists, typically used for diabetes, weight loss, and heart conditions, have shown potential in addressing neuroinflammation and neurodegeneration
• The combination treatment results were compelling: While buntanetap alone restored cognitive function to 100% and dulaglutide alone to 80%, the combination restored and also enhanced cognitive function beyond levels seen in healthy controls

Annovis Bio (NYSE: ANVS), a late-stage clinical drug platform company, announced new preclinical data demonstrating lead compound buntanetap’s potential to synergistically enhance cognition when used in combination with the glucagon-like peptide 1 (GLP-1) agonist dulaglutide (Trulicity(R)) in a mouse model of Alzheimer’s disease (https://ibn.fm/9WpKW).

GLP-1 agonists, such as dulaglutide, are known for their ability to manage blood sugar levels in diabetes patients and are also commonly used for weight loss or heart conditions. However, recent research suggests they also have neuroprotective properties, potentially reducing neuroinflammation and supporting neuronal health. When used alongside buntanetap, dulaglutide appears to amplify the cognitive benefits, suggesting a powerful new approach for treating neurodegenerative conditions.

Buntanetap (formerly Posiphen) works by targeting multiple pathways involved in neurodegenerative diseases. It inhibits the production of neurotoxic proteins that lead to the death of neurons, thereby slowing or stopping disease progression. Dulaglutide, on the other hand, activates the GLP-1 receptor, which has been shown to enhance insulin signaling in the brain, reduce inflammation, and promote cell survival. The combination therapy leverages these complementary mechanisms, aiming to provide a more effective treatment option.

The latest preclinical data builds on 2018 research demonstrating how buntanetap fully restored memory, learning, and synaptic potentiation in an Alzheimer’s mouse model. The company now aimed to determine whether buntanetap combined with dulaglutide would produce a synergistic effect in the same animal model. The results were compelling: while buntanetap alone restored cognitive function to 100% and dulaglutide alone to 80%, the combination restored and also enhanced cognitive function beyond levels seen in healthy controls.

“We are excited to see that buntanetap significantly amplifies the effects of dulaglutide on memory and learning, with a 6- to 10-fold increase in efficacy,” said Maria Maccecchini, Ph.D., Founder, President, and CEO of Annovis Bio. “This synergy is particularly important for enhancing treatment outcomes while minimizing potential side effects. As the field of Alzheimer’s research shifts towards combination therapies, we believe our approach holds great promise for offering more effective treatment options for patients.”

The potential for buntanetap combined with dulaglutide to enhance cognitive function represents a significant advancement in the field of neurodegenerative disease treatment. With current treatments offering limited efficacy, this combination therapy could address a critical unmet need in an expanding market.

The neurodegenerative disease treatment market is substantial and growing, driven by an aging population and increasing incidence of conditions like Alzheimer’s Disease. Nearly 7 million Americans are currently suffering from Alzheimer’s Disease, a figure projected to rise to almost 13 million by 2050. Alzheimer’s care costs are expected to reach $360 billion in 2024 and escalate to nearly $1 trillion annually by 2050 (https://ibn.fm/kCfQN). Annovis Bio’s innovative approach with buntanetap, especially when combined with dulaglutide, positions the company to capture a significant market share.

For more information, visit the company’s website at www.AnnovisBio.com, and social channels
LinkedIn, X and YouTube.

NOTE TO INVESTORS: The latest news and updates relating to ANVS are available in the company’s newsroom at https://ibn.fm/ANVS

• The Trans-Hudson Orogeny (Corridor) stretches hundreds of kilometers across North America and includes a long history of successful mines, while remaining highly underexplored
• Fathom Nickel owns the commanding land position in the Rottenstone Domain region of the Trans-Hudson Corridor, with 122,000+ highly prospective hectares
• Fathom Nickel projects include the past-producing Rottenstone Mine, multiple high-grade deposits that remain open in all-directions, mineralization that the company continues to prove via surveys and drilling

Fathom Nickel (CSE: FNI) (FSE: 6Q5) (OTCQB: FNICF) is a Canadian junior mining exploration and development company focused on acquiring, exploring, and developing high-quality nickel, copper, and cobalt deposits. With a particular focus on the Rottenstone Domain of the Trans-Hudson Corridor in Saskatchewan, Canada, Fathom Nickel is actively exploring two key properties: the Albert Lake Property and the Gochager Lake Property. Last month, Fathom Nickel added to its leading land position in the region with the acquisition of the 10,000+ hectare Friesen Lake Project located 40 kilometers southwest of the historic Rottenstone Mine and 30 kilometers northwest of the historic Gochager Lake deposit.

The Trans-Hudson Corridor is recognized worldwide for its expansiveness and massive potential for its yet untapped metal-rich ground. It trends from North Dakota in the U.S. through Saskatchewan where it veers east to include Northern Manitoba, and across Hudson’s Bay to include the Ungava Peninsula, PQ, from where it continues into Greenland. Coincident with the Trans Hudson Corridor are the world-class Thompson Nickel Belt, MN (in production), the Lynn Lake Nickel Belt (past producer), and the Raglan Nickel Belt, PQ (in production).

Fathom Nickel’s Albert Lake property is a promising exploration target. Formerly home to the high-grade Rottenstone Mine, this expansive landholding offers significant potential for magmatic nickel sulfide mineralization. Through the addition of the Tremblay-Olson Claims in 2022, the 100%-owned property now encompasses over 90,000 hectares. Fathom’s ongoing exploration efforts aim to unlock the full potential of this historically productive mining area.

Fathom Nickel’s Gochager Lake Property is a strategic asset. Acquired in stages throughout 2022 and 2023, the property now encompasses over 22,000 hectares. Its prime location within the Proterozoic Trans-Hudson Orogeny, a region renowned for hosting significant mineral deposits, underscores its exploration potential. The property hosts the historic Gochager Lake nickel-copper-cobalt deposit, the Mal Lake nickel occurrence, and the Borys Lake VMS zinc-lead-copper deposit, offering multiple avenues for exploration and development.

Recent Exploration Successes at Gochager Lake:

• Fathom Announces Mal Lake Nickel-Copper-Cobalt Mineralization: Recent drilling at the Mal Lake occurrence uncovered evidence of nickel-copper-cobalt mineralization, indicating potential for further exploration beyond the historic Gochager Lake deposit.
• Fathom Continues to Expand the Historic Gochager Lake Deposit: Ongoing drilling programs have shown success in expanding the known boundaries of the Gochager Lake deposit in all directions. This suggests a potentially larger resource base than previously estimated.
• Fathom Announces Receipt of New Exploration Permit and Commencement of Field Activities: In June 2024, Fathom received a new exploration permit for the Gochager Lake Property, allowing for continued drilling and exploration activities (e.g., 60 drill holes, 25-person camp).

A Staking Frenzy

Fathom Nickel CEO and VP Exploration Ian Fraser has a lengthy history of mining success. His C.V. includes exploration to development at Casa Berardi Gold Mine (Hecla Mining, PQ), Chief Geologist Komis Gold Mine (Waddy Lake Resources, SK), and Cisneros Gold Mine (Antioquia Gold, Colombia SA), amongst others. He recently summarized his excitement for this region when announcing the acquisition of the Friesen Lake property.

“It is very intriguing to us that >1 g/t Pt-Pd occurs in historic surface trenching and that significant Pt-Pd has been confirmed in historic drilling at Friesen Lake. The recent Ramp Metals Inc. drill result announcement has brought a lot of attention to the area and a bit of a staking rush. We felt it was important for Fathom to secure these dispositions and cover these known Ni-Cu-Pd-Pt showings before the staking frenzy grabbed this land ahead of us.”

Fraser was referencing the recent high-grade gold discovery by Ramp Metals of 73.55 g/t gold (“Au”) over 7.5 meters at its Rottenstone SW project that has catapulted the company’s market cap forward several multiples.

Looking Ahead for Fathom Nickel:

The company’s focus soon will be on further exploration and development of its properties in this unfolding prolific region. Management has been incredibly meticulous and methodical in providing and adding to the historic resources, a strategy that will not waver, only accelerate, going forward. Upcoming work will include:

• Resource definition drilling. Fathom will aim to define the extent and quality of the nickel, copper, and cobalt mineralization at Gochager, Albert, and Friesen Lake projects through continued drilling programs. This will be crucial for attracting potential investors and moving towards mine development.
• Metallurgical testing. Understanding how the minerals respond to various processing techniques is essential. Metallurgical testing will help determine the optimal methods for extracting the target metals.

Fathom Nickel’s recent exploration successes at the Gochager Lake project speak volumes about the potential for the area of Saskatchewan where it holds a dominant land position. The company’s focus on a historically known mineralized area with evidence of expansion potential and multiple mineral types (nickel, copper, cobalt) is encouraging. Investors interested in the junior mining sector and the potential for nickel exploration success should closely follow Fathom Nickel’s ongoing exploration activities and future announcements.

For more information, visit the company’s website at www.FathomNickel.com.

NOTE TO INVESTORS: The latest news and updates relating to FNICF are available in the company’s newsroom at https://ibn.fm/FNICF

• This has been the company’s most profitable quarter in the last eight years, according to CEO Rob McEwen
• Revenue was up 38%, driven by an increase in gold prices and the amount of gold equivalent ounces sold
• Infill drilling at Los Azules copper project has been completed, confirming the geological model and the high-grade zone
• New Argentinian legislation designed to facilitate foreign investment is expected to significantly improve the economics of the Los Azules project and lower risks for investors

McEwen Mining (NYSE: MUX) (TSX: MUX), an asset rich diversified gold and silver producer in the Americas with a large exposure to copper through its subsidiary McEwen Copper, released its second-quarter and half-year 2024 financial results for the period ended June 30, 2024, along with key updates regarding the current mining situation in Argentina and infill drilling results at its Los Azules project.

According to CEO and Chairman Rob McEwen during a conference call discussing the financial results, this has been the company’s most profitable quarter since 2016, with revenue growing by 38% and overall production costs expanding by 8% quarter-over-quarter. Higher revenues, driven by a 21% increase in realized gold prices and a 13% increase in gold equivalent ounces (“GEOs”) sold also drove improvements in gross profit, which reached $10.8 million in Q2, while adjusted EPITDA was $7.2 million (https://ibn.fm/RjVCr).

Production from the company’s three operating mines (Gold Bar in Nevada, Fox in Ontario, and San José in Argentina) was 35,265 GEOs in Q2, with plans remaining in effect to produce 130,000-145,000 GEOs overall for 2024.

“McEwen Copper continues to grow in value – based on the most recent injection of capital at $30 per share the implied market value is now $947 million, with MUX owning 48.3% or $457 million. That is 106% of MUX’s current fully diluted market capitalization,” McEwen added.

In addition to its silver and gold projects, McEwen Mining also owns a 48.3% interest in McEwen Copper Inc., which holds a 100% interest in the Los Azules copper project in San Juan, Argentina, and the Elder Creek exploration project in Nevada, U.S. During the conference call the company shared important updates regarding the mining situation in Argentina and the latest infill drilling results at Los Azules.

More specifically, Argentine President Javier Milei introduced new legislation encouraging large domestic and foreign investments in the country, offering significant tax and foreign exchange incentives to companies investing in key sectors of the economy, including mining. “We are excited about these changes as they open the door for many infrastructure investments in Argentina and significantly improve the economics of the Los Azules project and lower risks for investors,” the company said (https://ibn.fm/0i7Cc).

Additionally, the world’s largest mining company, BHP, and Lundin Mining recently completed a $4.4 billion joint acquisition of two copper deposits located in the same province in Argentina as McEwen Mining’s Los Azules. “We believe that this transaction is a convincing demonstration of San Juan and Argentina´s attractiveness for large‑scale mining projects and evidence of Argentina moving towards becoming a Tier 1 mining jurisdiction.”

McEwen also reported that infill drilling at Los Azules has been completed and the results are validating the geological model and the high-grade zone at the project. “During the 2023–2024 drilling season, over 70,000 meters were completed, that have strengthened the interpretation of the geological model in addition to extending the supergene enrichment zone mineralization, both at the edges and to depth. Resource drilling for the Los Azules Feasibility Study is now complete, and the study remains on track for delivery in early 2025,” the company said.

A replay of the conference call can be accessed at https://ibn.fm/f2EiB.

For more information, visit the company’s website at www.McEwenMining.com.

NOTE TO INVESTORS: The latest news and updates relating to MUX are available in the company’s newsroom at http://ibn.fm/MUX

• Torr Metals is lighting up the map by advancing three high-potential copper and gold projects in Canada, all located in prime mining jurisdictions with increasing M&A activity by major mining companies
• Each of Torr’s projects boasts key traits sought by majors: high-grades, prime location, robust infrastructure, full project ownership, and significant scalability
• The company’s assets are situated near major mining operations, including Canada’s largest open-pit copper mine at Highland Valley, within regions rich in mining history and established infrastructure
• With projects positioned in some of Canada’s most prolific mining regions, Torr Metals is well-placed to attract attention from industry giants

Unparalleled Infrastructure and Strategic Locations

Imagine your exploration project nestled among some of the biggest names in mining—Teck’s Highland Valley Mine, Newmont’s-Imperial Metals Red Chris Mine, and New Gold’s New Afton Mine, just to name a few. That’s where Torr Metals (TSX.V: TMET) finds itself with the Kolos Copper-Gold Project in British Columbia’s Quesnel Trough, a region pulsing with mining history and supported by infrastructure that keeps costs low and operations running year-round. The Kolos Project isn’t just strategically positioned; it’s a short drive away from Canada’s largest open-pit copper mine, connected by highways with easy access to the vibrant mining town of Merritt.

And it doesn’t stop there. Torr’s Filion Project in northern Ontario sits right off the Trans-Canada Highway, with rail and power infrastructure at its doorstep, making it a prime potential target for the next big gold discovery. Then there’s the Latham Project, anchored in BC’s legendary “Golden Triangle,” an area so rich in minerals that even the highways—like Highway 37 transecting the project, currently seeing a $195 million upgrade—seem to glitter with promise.

Full Control and Massive Potential Upside

Torr Metals is sitting on a portfolio of fully owned, high-stakes copper and gold exploration projects with immense untapped potential. With 100% ownership of the Kolos, Filion, and Latham projects, Torr has the freedom to explore, develop, and strike deals without the complications that come with partial ownership. This autonomy gives Torr a powerful edge, making it a highly attractive potential partner joint ventures and strategic investments.

But what truly sets Torr apart is the sheer scale of its ambitions. The Kolos Project spans a whopping 240 km2, nestled in the same geological belt as some of the biggest copper mines in the country. The Filion Project stretches across 261 km2 in an underexplored greenstone belt, ripe for high-grade orogenic gold discovery potential. And the Latham Project? It’s a mammoth 689 km2 playground with an existing copper-gold porphyry deposit at Gnat Pass, located adjacent to Highway 37 within the “Golden Triangle,” a region renowned for its world-class mineralization.

A Future Forged in Critical Minerals

As the world races towards a clean energy future, Torr Metals is poised to be a key player, exploring the critical and precious minerals that will power tomorrow. With projects that tick all the boxes — high grade, prime location, infrastructure, ownership, and scalability—Torr Metals stands out as a beacon of opportunity in the mining sector. As the company ramps up its exploration efforts, it’s clear that the future is bright and full of potential.

For more information, visit the company’s website at www.TorrMetals.com.

NOTE TO INVESTORS: The latest news and updates relating to TMET are available in the company’s newsroom at https://ibn.fm/TMET

• The “Quantum Programming Core” course experienced a 53% rise in enrollments, while total enrollments, including both the “Core” and “Foundations for Quantum Programming” courses, increased by 85%
• D-Wave provides access to its Leap(TM) quantum cloud service in 42 countries, allowing learners to utilize D-Wave software and tools including the Ocean(TM) SDK
• Nearly 90% of learners that have completed a D-Wave training course recommend it

D-Wave Quantum (NYSE: QBTS), a leader in quantum computing systems, software, and services, and the first commercial provider of quantum computers, recently announced a significant increase in enrollment for its quantum training courses. In the first half of 2024, the enrollment numbers saw double-digit growth compared to the same period in 2023 (https://ibn.fm/n5wXd).

The “Quantum Programming Core” course experienced a 53% rise in enrollments, while total enrollments, including both the “Core” and “Foundations for Quantum Programming” courses, surged by 85%. This notable growth highlights a global effort to train workers to meet the rapidly expanding demand for quantum computing expertise.

“With rapidly increasing demand for quantum-ready talent and a shortage of quantum-trained workers, we’re at a critical crossroads with quantum education,” said Victoria Goliber, D-Wave’s head of technical advising. “Our learning solutions foster an environment of experimentation and innovation that helps streamline and expedite skills training to prepare the workforce now in order to meet the growing need for quantum optimization capabilities.”

This surge in demand for quantum programming skills is driven by forecasts indicating that less than half of all anticipated quantum computing job openings will be filled by 2025, as reported by McKinsey. Supporting this prediction, a 2024 Hyperion Research survey commissioned by D-Wave revealed that businesses currently utilizing quantum computing cite the lack of in-house quantum expertise as a major challenge. Furthermore, nearly all government quantum initiatives across various countries, including Australia, Canada, the European Union, Japan, the United Kingdom, and the United States, now prioritize quantum workforce development.

To address this need, D-Wave offers accessible and thorough training solutions to prepare professionals for success in the quantum computing field. The “Foundations for Quantum Programming” course is designed to help beginners develop their math and Python skills, leading up to the more advanced “Quantum Programming Core” course. As part of its global workforce development efforts, D-Wave provides access to its Leap quantum cloud service in 42 countries, allowing learners to utilize D-Wave software and tools including the Ocean SDK. In Canada, students, staff, and researchers at post-secondary institutions can access D-Wave technology for free through the Leap service, thanks to an expanded training initiative in collaboration with Canada’s Quantum Algorithms Institute.

“In most of the data analytics teams, we don’t represent problems in a binary format, which is generally required to work with a quantum computer,” said Ziya Dalkılıç, data scientist at Ford Otosan, a joint venture between Ford Motor Company and Koç Holding, an industrial conglomerate based in Turkey. “I think it is quite important to learn how to represent those problems in the fashion that a quantum computer needs. This course has been fundamental in providing that knowledge before tackling a real-world problem.”

D-Wave’s training program emphasizes practical applications rather than theoretical concepts and physics. It demonstrates how quantum computing can address real-world problems such as workforce scheduling, logistics routing, production planning, and resource allocation. Nearly 90% of learners that have completed a D-Wave course recommend it, appreciating the well-structured, easy-to-follow materials and the practical approach tailored for individuals with minimal coding experience.

For more information, visit the company’s website at www.DWaveQuantum.com.

NOTE TO INVESTORS: The latest news and updates relating to QBTS are available in the company’s newsroom at https://ibn.fm/QBTS

Forward Looking Statements

Certain statements in this press release are forward-looking, as defined in the Private Securities Litigation Reform Act of 1995. These statements involve risks, uncertainties, and other factors that may cause actual results to differ materially from the information expressed or implied by these forward-looking statements and may not be indicative of future results. These forward-looking statements are subject to a number of risks and uncertainties, including, among others, various factors beyond management’s control, including the risks set forth under the heading “Risk Factors” discussed under the caption “Item 1A. Risk Factors” in Part I of the company’s most recent Annual Report on Form 10-K or any updates discussed under the caption “Item 1A. Risk Factors” in Part II of the company’s Quarterly Reports on Form 10-Q and in the company’s other filings with the SEC. Undue reliance should not be placed on the forward-looking statements in this press release in making an investment decision, which are based on information available to the company on the date hereof. The company undertakes no duty to update this information unless required by law.

• The company provided updates for its study programs for 2024, with a focus on its glucagon-like peptide-1 (“GLP-1”) agonist research program, targeting a significant step up in addressing worldwide diabetes and obesity, a tremendous market
• Lexaria has its Human Pilot Study #3 lined up, as well as its chronic dosing human study, both studies will begin dosing later this year

Lexaria Bioscience (NASDAQ: LEXX), a global innovator in drug delivery platforms, just released its fiscal report for the third quarter of the 2024 financial year (“Q3, 2024”). Of note was growth in cash and marketable securities from $1.5 million during the same period in the 2023 financial year to $8.5 million as of May 31, 2024. The company reduced certain R&D expenditures and experienced other savings (https://ibn.fm/HWe5d).

Most importantly, however, were the program updates for initiatives it embarked on for 2024. A highlight of its projects has been its glucagon-like peptide-1 (“GLP-1”) agonist research program. GLP-1, a class of drugs, has demonstrated an ability to significantly address diabetes and obesity. What Lexaria’s unique drug delivery platform offers is the added ability to greatly improve the otherwise poor oral bioavailability of GLP-1 drugs, making it possible for simple oral application versus traditional injection, an opportunity of huge implication in the marketplace.

Human pilot study #1, utilizing Novo Nordisk’s(R) semaglutide (Ozempic(R), Rybelsus(R)) was reported on in January 2024, and human pilot study #2, using the same drug, is expected to be reported on in August and September, 2024.

Lexaria has made notable progress, having commenced another research program, the completion of which is set for August. This program will be executed by the National Research Council of Canada (“NRC”). It will seek to evaluate the molecular properties of DehydraTECH-processed pure semaglutide using simulated gastric fluid, which mimics conditions in the human gut.

Lexaria also looks to follow through with its chronic (12-week) dosing human study set to be carried out in Australia. This study, which will involve 70-90 human study subjects with pre-diabetic and Type 2 diabetic conditions, will be run in Australia, and preparations have already begun. It will leverage the use of Rybelsus as a positive control, and then in four additional separate arms, DehydraTECH-processed 1) semaglutide, 2)CBD, 3) tirzepatide, and 4) combo CBD plus semaglutide This larger study will be registered as a Phase 1 level study and carried out into 2025.

Human Pilot Study #3 is also in the pipeline, a study that will enroll up to eight healthy human volunteers, intending to evaluate DehydraTECH’s effectiveness in combination with a dual action GLP-1 agonist and glucose-dependent insulinotropic peptide (“GIP”) drug, Eli Lilly’s(R) well-known tirzepatide. The study will aim for several endpoints, including blood sugar, pharmacokinetics, and tolerability. Already, the company has brought a contract research organization (“CRO”) to run the study and is expecting to begin dosing in September.

Lexaria is bullish about its GLP-1 studies, since revenues for this product class exceeded $31 billion, with the market projected to grow significantly in the coming years. The company continues to make progress toward this extremely high-value target.

For more information, visit the company’s website at www.LexariaBioscience.com.

NOTE TO INVESTORS: The latest news and updates relating to LEXX are available in the company’s newsroom at https://ibn.fm/LEXX

• ECGI Holdings is targeting a share of the growing luxury goods market by designing, manufacturing, and selling luxury equestrian apparel and equipment through its subsidiary Pacific Saddlery
• The company sees the utilization of smaller focused markets as a proven entrance pathway to much larger general luxury markets
• Bain & Company valued the global luxury goods market at €362 billion ($395.4 billion) in 2023 and expects this market to grow to between €540 billion ($589.8 billion) and €580 billion ($633.5 billion) by 2030
• ECGI Holdings and Pacific Saddlery are using celebrated brands like Hermès, Gucci, and Ralph Lauren as a template for what’s possible in the luxury market
• Throughout their respective histories, celebrated luxury brands have continuously incorporated equestrian elements into their designs to capitalize on the timelessness, prestige, and positive connotation attached to horses

ECGI Holdings (OTC: ECGI), a diversified holding company focused on luxury fashion, equestrian, and viticulture markets, recognizes that a marginal share of a globally large market would translate to more revenue annually than even a big share of a small market, and sees smaller focused markets as a proven entrance pathway to much larger general luxury markets.

To put the figures and logic into perspective, Bain & Company published its annual Luxury Goods Worldwide Market Study, which noted that the personal luxury goods segment of the overall luxury market recorded €362 billion ($395.4 billion) in spending in 2023. This represented a 4% increase over 2022 figures (at January 2024 exchange rates) or an 8% increase (at constant exchange rates) (https://ibn.fm/vxiS2).

Anchoring this increase was the growth in all personal luxury goods categories, including accessories, apparel, beauty, watches, and jewelry. Looking ahead, Bain & Company forecasts moderate growth in the personal luxury goods segment in 2024, ranging between 1% and 4%. Beyond 2024, the analysis report projects that the market will post annual growth rates of 5% to 7%, reaching €540 billion ($589.8 billion) to €580 billion ($633.5 billion) by 2030. (For ECGI Holdings, therefore, a marginal share of this market would translate to millions of dollars in revenue through 2030.)

With the study urging luxury brands to focus on creativity and innovation “to enhance relevance to consumers, with the ultimate goal of continuing to expand their client bases while cultivating brand lovers,” fashion houses are expected to continue incorporating timeless trends and elements that have endured seasons and events. And when it comes to timelessness, few things come close to the allure and symbolic power of the upscale equestrian market.

For ages, horses have represented royalty, nobility, and grace. Fast forward to today, high-end fashion brands like Hermès (OTC: HESAF), Ralph Lauren (NYSE: RL), and Gucci, which is part of Kering Group (OTC: PPRUF), celebrated designers like Stella McCartney, and mainstream fashion houses have incorporated equestrian aesthetics and motifs into their creations. ECGI Holdings, too, has jumped on this bandwagon through Pacific Saddlery, its subsidiary and leading manufacturer and retailer of equestrian apparel, tack, equipment, and accessories.

These brands have converted what would otherwise be considered ordinary riding attire and accessories into symbols of luxury and sophistication, targeting affluent consumers who invest in high-end products and services related to horse care and horse riding. By embracing equestrian chic, these fashion houses have continued to move the needle in the growing luxury equestrian market, a niche segment of the luxury goods and luxury markets.

Valued at tens of billions of dollars, the luxury equestrian market is segmented into two: the luxury equestrian apparel segment, which covers the design, production, and sale of high-end riding gear like helmets, boots, jackets, and breaches, and the luxury equestrian tack and equipment segment, which comprises brands that manufacture premium saddles, bridles, and tack.

For its part, Pacific Saddlery creates products for both segments. Having initially focused on the equestrian tack and equipment segment – a focus that saw it manufacture and sell bridles, reins, and martingales under its celebrated Allon brand – Pacific Saddlery is preparing to launch a new collection of equestrian apparel under this brand (https://ibn.fm/QJb9S).

Through this launch, Pacific Saddlery will follow a path trodden by Hermès before it. A French luxury design house, Hermès was established in 1837 as an artisanal workshop that primarily crafted harnesses. It then went on to introduce made-to-measure saddles, beginning in the 1880s, before introducing additional products. Today, Hermès is a celebrated brand that makes products across various métiers that contributed to consolidated revenue in the first half of 2024 of €7.5 billion ($8.19 billion) (https://ibn.fm/WZINc).

Pacific Saddlery and ECGI Holdings are nonetheless not out to replicate Hermès’ and other established luxury brands’ models exactly; rather, they wish to use such brands as an inspiration of what is possible if they adopt and maintain the required level of creativity, innovation, and strategic decision-making. This approach, ECGI Holdings hopes, will help it expand its customer base and, as a result, grow its market share in the luxury goods and luxury equestrian markets, leading to significant revenues.

For more information, visit the company’s website at www.ECGIHoldings.com.

NOTE TO INVESTORS: The latest news and updates relating to ECGI are available in the company’s newsroom at https://ibn.fm/ECGI

• Clene has conducted five Phase 2 clinical trials, three with long-term extensions, and three expanded access programs (with additional studies ongoing) to evaluate the safety and efficacy of CNM-Au8
• The global ALS treatment market is poised for growth, driven by an aging population and limited current treatment options
• CNM-Au8 works by improving cellular energy production and utilization, which is crucial for maintaining neuronal health, and is at a deficit in neurodegenerative diseases

Clene (NASDAQ: CLNN) and its wholly owned subsidiary Clene Nanomedicine Inc. is a clinical-stage biopharmaceutical company focused on improving mitochondrial health and protecting neuronal function to treat neurodegenerative diseases, including amyotrophic lateral sclerosis (“ALS”) and multiple sclerosis (“MS”). In the recent Emerging Growth Conference 73 on July 17-18, 2024, CEO Rob Etherington and CFO Morgan Brown presented new findings and information about the company and its lead drug candidate, pertinent to current and potential investors.

In the opening of the presentation, Etherington explained that mitochondria play a vital role in cellular metabolism and energy production, and that impaired mitochondrial function is a significant issue in neurodegenerative diseases. Clene’s lead agent, CNM-Au8(R), works by improving cellular energy production and utilization via the nicotinamide adenine dinucleotide (NAD+) pathway, which is crucial for maintaining neuronal health. By addressing mitochondrial dysfunction, CNM-Au8 provides neuroprotection and promotes remyelination, potentially altering the course of debilitating neurodegenerative diseases. This innovative approach aims to restore and protect neurological function (https://ibn.fm/j7gYH).

CNM-Au8 is being investigated to treat neurodegenerative diseases in clinical studies and comprehensive compassionate use programs in ALS, MS, and even one study in Parkinson’s Disease, Etherington explained.

The Clene CEO also highlighted the strong safety profile of CNM-Au8, with over 650 years of cumulative subject exposure and no serious adverse events linked to the drug. Extensive clinical trials have been conducted to evaluate its safety and efficacy. Phase 2 trials for ALS have shown improved survival rates and delayed clinical worsening. Additionally, significant improvements in biomarkers and functional outcomes were observed.

The company is now preparing for Phase 3 studies for both ALS and MS, while seeking feedback from the Food and Drug Administration on a potential pathway for accelerated approval for CNM-Au8.

The global ALS treatment market is expected to grow significantly due to the increasing prevalence of the disease among the aging population. Grand View Research reports that the market is anticipated to reach $885.5 million by 2026, but the growth may be hindered by the high costs associated with ALS treatments (https://ibn.fm/cprPz).

According to Etherington, ALS is more common than thought, and treatment options are severely limited both in the United States and worldwide, making the potential impact of CNM-Au8 even more significant. Department of Health Resources & Services data indicate that the estimated prevalence of ASL in the U.S. was 5.2 per 100,000 people in 2015.

Etherington further noted that CNM-Au8’s ability to penetrate the blood-brain barrier and its neuroprotective properties make it a promising candidate not only for ALS and MS but also for other neurodegenerative diseases.

As the company continues to make significant strides in addressing critical unmet needs in the market, its innovative approach, robust intellectual property portfolio, and promising clinical data position Clene as a leading entity in the field of neurodegenerative disease treatment.

For more information, visit the company’s website at www.Clene.com.

NOTE TO INVESTORS: The latest news and updates relating to CLNN are available in the company’s newsroom at https://ibn.fm/CLNN

• Domestic violence worldwide is fostering a concerted response by criminal justice officials and legislators upset by the deadly fallout of offenders who violate court-ordered protective measures for victims
• Tennessee recently passed a statewide law establishing specific targets for electronic monitoring of offenders via GPS and communication with victims, creating clear and timely awareness of situations in which offenders are in proximity to victims
• Electronic monitoring technology innovator SuperCom Ltd. has developed a suite of hardware, connectivity, and software components designed to target the market for monitoring domestic violence offenders and alerting their victims to dangers
• SuperCom recently reported over $11 million in new revenue for the company from European clients, placed within three months

The severe consequences of domestic violence incidents are driving the monitoring of offenders’ whereabouts via electronic GPS-enabled technologies.

Tennessee enacted a law last month described as the first in the nation to codify measures statewide requiring electronic GPS monitoring (“EM”) for people arrested for stalking, aggravated stalking or especially aggravated stalking. The law also encompasses offenses related to assault, kidnapping, or rape, targeting a specific person, and allowing victims of such crimes to be notified through a phone app when offenders, in their cases, move close to their location.

“Those critical seconds of giving a victim the ability to know that someone is outside or near them puts them in a different space and gives them more tools”, said Alex Youn, a relative of a Tennessee mother-daughter duo killed in an incident that inspired passage of the law (https://ibn.fm/hHL3G).

EM solutions developer SuperCom (NASDAQ: SPCB) is advancing its technological innovations as a means of combatting the rising incidence of domestic partner stalking and attacks, not only in the United States but around the world. “People have been trying to do electronic monitoring for over 30 years, but many of the times they ran into technological hurdles,” company President and CEO Ordan Trabelsi said during a Your Advantage Play podcast interview (https://ibn.fm/T0zX5). “With every project, we’re able to be one step ahead of the curve.”

SuperCom’s PureSecurity suite of hardware, connectivity, and software components is emerging as a powerful tool for governments and private organization clients. The company recently celebrated $11 million in new European orders within three months (https://ibn.fm/Vu6XB). SuperCom’s technology is primarily designed for offender monitoring, ensuring that individuals under legal restrictions are accurately tracked, while also being adaptable for related needs such as tracking Alzheimer’s patients prone to wandering. The company also offers identification solutions, such as electronic passports, biometric visas, driver licenses, and voter authentication capabilities. Moreover, the primary focus is on the criminal offender monitoring space. It is a niche sector with relatively few competitors, and SuperCom sees it as the sector with the greatest opportunities.

Statistics generated by the Maricopa County Attorney’s Office in Arizona indicate that, nationwide, people are physically abused by an intimate partner at a rate of 20 per minute, amounting to millions of incidents per year. The report indicates that about 100 fatalities in the state each year are due to domestic violence, including not only the partner targeted but Good Samaritan bystanders and first responders. The report also points to a 2017 study by the Centers for Disease Control and Prevention, estimating that almost 40% of people in Arizona had been subject to some form of domestic abuse (https://ibn.fm/KAqXr).

Tennessee, where the landmark EM protection bill was passed into law last month, is the seventh-most deadly state for incidents of men attacking women, according to a domestic shelter executive. Thirteen other states have also begun using GPS tracking to limit the risks associated with domestic violence offenders, revealing the growing market for products such as SuperCom’s platform (https://ibn.fm/gGYnC).

For more information, visit the company’s website at www.SuperCom.com.

NOTE TO INVESTORS: The latest news and updates relating to SPCB are available in the company’s newsroom at http://ibn.fm/SPCB